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All Journal Journal of Islamic Medicine Jurnal Pengabdian Teknologi Tepat Guna Jurnal Medicare
Sandhori, Fajar Jamaluddin
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Religion Computer Science & IT Engineering Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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Aktivitas Anti Trombotik dari Genus Curcuma : Kajian Sistematik Sandhori, Fajar Jamaluddin; Kusumawati, Idha; Samirah, Samirah; Rullyansyah, Subhan; Ramadhani, Firmansyah Ardian; Prasetyawan, Hanif Rifqi; Warsito, Mega Ferdina
Journal of Islamic Medicine Vol 8, No 2 (2024): JOURNAL OF ISLAMIC MEDICINE EDISI SEPTEMBER 2024
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v8i2.25929

Abstract

Background : The Curcuma genus has various pharmacological activities, one of these is antithrombotic activity by preventing thrombus formation. Some of its chemical contents are also known to inhibit thrombus formation including curcumin, bisdemethoxycurcumin, ar-turmerone, and xanthorrizhol compounds. Antithrombotic drugs are used for the prevention and treatment of thrombosis whose mechanisms are divided into anticoagulants, thrombolytics, and antiplatelets. Objective: This review article discusses the potential of Curcuma genus as antithrombotic, including anticoagulant, antiplatelet, and thrombolytic, Methods: This study was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method using four databases : PubMed, ScienceDirect, Scopus, and Google Scholar from July to December 2023. The inclusion criteria used were articles on antithrombotic activity, including anticoagulants, antiplatelets, and thrombolytics from the genus Curcuma. Results: The number of articles obtained from four databases was 3413 articles. Furthermore, based on the results of filtering duplicate articles from all databases, 2771 articles were selected and then continued with screening based on inclusion and exclusion criteria until 15 articles were selected as material for systematic review. Conclusion: Curcuma species that have potential as antithrombotic are Curcuma longa, Curcuma zedoaria Rosc., Curcuma amada, Curcuma caesia, Curcuma aeruginosa, Curcuma latifolia, Curcuma aromatica Salisb, Curcuma wenyujin, and Curcuma xanthorrhiza
SKRINING FITOKIMIA DAUN TEH HIJAU (CAMELLIA SINENSIS L.) DAN BIJI LADA HITAM (PIPER NIGRUM L.) Sandhori, Fajar Jamaluddin; Hanif Rifqi Prasetyawan; Farida Istiqamah; Ilham Robbynoor Sulistiyono; Rizkiyatul Hasanah
Jurnal Medicare Vol. 4 No. 3: JULY 2025
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v4i3.233

Abstract

Plants are the main source of secondary metabolites that have important biological potential. This study aims to screen the phytochemicals of green tea leaves and black pepper to identify the classes of active compounds contained within them. Extraction was performed using the maceration method with 96% ethanol over three days, followed by qualitative phytochemical testing (alkaloids, flavonoids, saponins, tannins, triterpenoids, steroids, polyphenols, and anthraquinones). Green tea leaves contain alkaloids, triterpenoids, flavonoids, polyphenols, and anthraquinones. Black pepper contains alkaloids, saponins, triterpenoids, steroids, and flavonoids, but does not contain polyphenols, tannins, or anthraquinones. The differences in the composition of active compounds indicate distinct therapeutic potentials in the two plants and support their use as natural medicinal ingredients.
Training on Hand Soap Formulation Using Caesalpinia sappan (Sappanwood) Ambarwati, Nadya; Indriani , Novamei; Vibrianita Nidom, reviany; Marfuatin Nur, Fikria; Jamaluddin Sandhori, Fajar; Purbosari, ira; Rahayu, asti; Wido Mukti, asri; Pramushinta, iak; Rifqi Prasetyawan, Hanif; rismawati
JURNAL PENGABDIAN TEKNOLOGI TEPAT GUNA Vol 6 No 3 (2025): Teknologi Tepat Guna (TTG)
Publisher : Universitas Sahid Surakarta

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Abstract

: This community service aims to increase the capacity of community skills in utilizing local biological resources, especially secang wood (Caesalpinia sappan L.), as an active ingredient in making natural-based handsoap with bioactive compounds such as brazilin, tannins, and flavonoids that have antibacterial, antioxidant, and anti-inflammatory properties, as environmentally friendly hygiene products. The training will be carried out through a theoretical and practical approach, which includes the introduction of the chemical characteristics of sappang wood, active ingredient extraction techniques, natural soap formulation, production process, and equipped with basic materials for product packaging and marketing strategies, especially in the context of micro business development and promotion through digital media. From the results of the community service program about education on Handsoap Making Training Using Secang Wood, it can increase the insight and knowledge of the residents of RT Wage Sidoarjo and can improve the community's economy.
Training on Hand Soap Formulation Using Caesalpinia sappan (Sappanwood) Ambarwati, Nadya; Indriani , Novamei; Vibrianita Nidom, reviany; Marfuatin Nur, Fikria; Jamaluddin Sandhori, Fajar; Purbosari, ira; Rahayu, asti; Wido Mukti, asri; Pramushinta, iak; Rifqi Prasetyawan, Hanif; rismawati
JURNAL PENGABDIAN TEKNOLOGI TEPAT GUNA Vol 6 No 3 (2025): Teknologi Tepat Guna (TTG)
Publisher : Universitas Sahid Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47942/jpttg.v6i3.2155

Abstract

: This community service aims to increase the capacity of community skills in utilizing local biological resources, especially secang wood (Caesalpinia sappan L.), as an active ingredient in making natural-based handsoap with bioactive compounds such as brazilin, tannins, and flavonoids that have antibacterial, antioxidant, and anti-inflammatory properties, as environmentally friendly hygiene products. The training will be carried out through a theoretical and practical approach, which includes the introduction of the chemical characteristics of sappang wood, active ingredient extraction techniques, natural soap formulation, production process, and equipped with basic materials for product packaging and marketing strategies, especially in the context of micro business development and promotion through digital media. From the results of the community service program about education on Handsoap Making Training Using Secang Wood, it can increase the insight and knowledge of the residents of RT Wage Sidoarjo and can improve the community's economy.
Co-Authors Farida Istiqamah Fikria Marfuatin Nur Firmansyah Ardian Ramadhani Idha Kusumawati Ilham Robbynoor Sulistiyono Indriani , Novamei Nadya Ambarwati Pramushinta, IAK Prasetyawan, Hanif Rifqi Purbosari, Ira Rahayu, Asti Rismawati Rizkiyatul Hasanah Samirah Samirah, Samirah Subhan Rullyansyah Vibrianita Nidom, reviany Warsito, Mega Ferdina Wido Mukti, Asri