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OPTIMASI EKSTRAK BIOAKTIF PROPOLIS MENGGUNAKAN MICROWAVE-ASSISTED EXTRACTION DENGAN RESPONSE SURFACE METHODOLOGY Marthia, Nabila; Triani, Rini; M, Nur Annisa Fitriana
Pasundan Food Technology Journal (PFTJ) Vol 12 No 3 (2025): PASUNDAN FOOD TECHNOLOGY JOURNAL
Publisher : Department of Food Technology, Universitas Pasundan, Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/pftj.v12i3.34939

Abstract

Propolis is a natural bee product rich in bioactive compounds such as flavonoids and phenols, which act as potent antioxidants and antimicrobials. This study aimed to optimize the extraction of propolis using the Microwave-Assisted Extraction (MAE) method through a Response Surface Methodology (RSM) approach and Central Composite Design (CCD). The independent variables were solvent volume (100–150 mL) and extraction time (5–8 min), while the responses measured included total flavonoids, total phenols, and antioxidant activity (IC₅₀). All responses followed a quadratic model with high coefficients of determination (R² > 0.9) and non-significant lack of fit. The optimum condition was achieved at 150 mL solvent volume and 6.5 min extraction time, with a desirability value of 0.98. Verification showed that experimental values fell within the 95% prediction interval, confirming the accuracy of the model. These results demonstrate that MAE is an efficient method for producing quality propolis extracts with strong biological potential.
Dental anxiety and its impact on oral health-related quality of life among Indonesian children aged 8–12 years: a cross-sectional study Anisyah, Ika; Oewen, Roosje R.; Triani, Rini; Sasmita, Inne S.; Andiesta, Niekla Survia
Padjadjaran Journal of Dentistry Vol 37, No 3 (2025): November 2025
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol37no3.62024

Abstract

Introduction: Dental anxiety in children is a common problem that affects their oral health-related quality of life (OHRQoL). It may persist into adulthood and become chronic. This study aimed to examine the relationship between dental anxiety and OHRQoL in children aged 8–12 years. Methods: A cross-sectional study was conducted on 199 children at Baitul Maal Islamic Elementary School, Jakarta. Dental anxiety was measured using the Children’s Fear Survey Schedule-Dental Subscale (CFSS-DS), and OHRQoL was assessed using the Child Oral Health Impact Profile-Short Form 19 (COHIP-SF19). Data were analyzed descriptively and with Pearson’s correlation analysis. Results: A total of 19.1% of children reported dental anxiety and 23.1% had poor OHRQoL. Pearson’s test revealed a significant but weak negative correlation between dental anxiety and OHRQoL (r = -0.148; p = 0.018), with R2 explaining 2.19% of the variance. Conclusion: Dental anxiety is associated with poorer OHRQoL; higher dental anxiety is associated with lower OHRQoL in children and accounts for approximately 2.19% of the variance in OHRQoL. Early interventions are essential to reduce anxiety and improve oral health outcomes.