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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Anatomica (Anatomica Medical Journal) JURNAL IBNU SINA BIOMEDIKA Buletin Farmatera JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK JURNAL ILMIAH KOHESI Jurnal Implementa Husada Jurnal Pandu Husada The Journal General Health and Pharmaceutical Sciences Research
Ilham Hariaji
Universitas Muhammadiyah Sumatera Utara
Religion Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Jus Buah Pare Efektif Menurunkan Kadar LDL Pada Tikus Galur Wistar Yang Diinduksi Pakan Tinggi Lemak Fitriani, Mutiara; Hariaji, Ilham
JURNAL PANDU HUSADA Vol 4, No 3 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v4i3.16562

Abstract

Abstrak: Dislipidemia merupakan ketidakseimbangan lipid dan merupakan salah satu faktor resiko dari penyakit. Dimana penyakit kardiovaskular menjadi salah satu penyebab utama kematian. Buah pare dikenal sebagai obat herbal yang memiliki kandungan bahan aktif untuk menurunkan kadar lipid dalam darah seperti flavonoid. Penelitian ini bertujuan untuk mengetahui potensi jus buah pare (Momordica charantia L.) dalam menurunkan kadar LDL pada tikus galur wistar yang diinduksi pakan tinggi lemak. Desain penelitian True Experiment dengan rancangan pretest – posttest with control group design dengan menggunakan 24 ekor tikus galur wistar yang diberi pakan tinggi lemak dan dibagi menjadi 4 kelompok yaitu kontrol negatif, kontrol positif, kelompok 1 (jus buah pare 1,8 mL) dan kelompok 2 (Jus buah pare 2,7 mL). Analisis data yang digunakan adalah uji Wilcoxon dan Uji T Berpasangan. Kadar LDL ditemukan bermakna turun pada pemberian jus buah pare 1,8 mL (p0,027) dan pemberian jus buah pare 2,7 mL (p0,028). Dapat disimpulkan jus buah pare (Momordica charantia L.) efektif dalam menurunkan kadar LDL pada tikus galur Wistar yang diinduksi pakan tinggi lemak.
Edukasi Banjir Dan Penyakit Pasca Banjir Pada Masyarakat Kelurahan Jati Nasution, Muhammad Rizki Ramadhan Bagaskara; Manurung, Muhammad Akbar; Shalin, Fonda Azarine; Murtanto, Dita Fazhari; Saidatul, Emma Dalen; Linda, Putri Cici; Hariaji, Ilham
JURNAL PANDU HUSADA Vol 4, No 3 (2023)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v4i3.16729

Abstract

Abstrak: Banjir terjadi karena volume air yang mengalir pada suatu sungai atau saluran drainase melebihi atau di atas kapasitas pengalirannya. Bencana alam seperti banjir dapat mengakibatkan berbagai masalah yang besar terutama persoalan kesehatan. Banjir dapat mengancam jiwa manusia dimulai dari penyakit hingga kematian jika tidak ditangani secara serius. Kegiatan ini bertujuan untuk mengedukasi Kesehatan tentang penyakit pasca banjir dengan menggunakan metode presentasi untuk meningkatkan pengetahuan masyarakat di kelurahan jati. Pengabdian ini dilaksanakan di kantor Kelurahan Jati, Kecamatan Medan Maimun pada agustus 2023. Kegiatan ini bertujuan untuk memberikan pengetahuan dan informasi kepada masyarakat dan meningkatnya kesadaran masyarakat untuk dalam upaya pencegahan penyakit pasca banjir, dan tercapainya pola hidup bersih dan sehat. Kesimpulan kegiatan pengabdian ini yaitu adanya peningkatan pengetahuan masyarakat setelah dilakukan pendidikan kesehatan mengenai masalah banjir, penyebab banjir, dampak banjir, pencegahan banjir, dan penyakit pasca banjir dan upaya pencegahan penyakit pasca terjadinya banjir.
Clinical Experiences: Edukasi Pengenalan Penyakit Diabetes Melitus Tipe 2 Di Lingkungan 6, Teladan Barat Zahran, Fadly; Gurusinga, Nabira Maharani; Putri, Rania Gusmi; Fauzio, Revo; Frisilia Saputri, Anggi Yulisna; Hariaji, Ilham
JURNAL PANDU HUSADA Vol 5, No 1 (2024)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v5i1.18982

Abstract

Abstrak : Jumlah penderita penyakit diabetes melitus di Indonesia terus mengalami peningkatan, sehingga dibutuhkan edukasi agar dapat menekan angka morbiditas dan mortalitas. Penelitian ini bertujuan untuk mendeskripsikan tentang masalah kesehatan keluarga di lingkungan 6, Teladan Barat. Observasi masalah kesehatan ini berkaitan tentang penyakit diabetes melitus tipe 2. Metode yang penelitian yang digunakan dalam penelitian ini menggunakan metode observasi (pengamatan), penggunaan kuesioner dan pendekatan terhadap keluarga secara langsung. Data penelitian ini adalah hasil observasi dan hasil pendekatan yang dilakukan ke keluarga terkait masalah kesehatan. Penganalisisan data dilakukan dengan pengumpulan data yang kemudian dilakukan pemilahan data serta mengklasifikasi data yang akhirnya menyajikan hasil dari observasi. Dari penyuluhan yang dilakukan didapatkan peningkatan tingkat pengetahuan
Clinical Experiences: Bahaya Obesitas Dan Cara Pencegahannya Lingkungan Jl. Tapian Nauli No 37a Kel.Teladan Barat Prayoga, Muhammad Iqbal; Bakhreni, Neyla Fitri; Shafira, Adinda; Jannah, Rhadatul; Nabila, Windy; Hariaji, Ilham
JURNAL PANDU HUSADA Vol 5, No 1 (2024)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v5i1.19007

Abstract

Abstrak: Obesitas merupakan salah satu masalah kesehatan yang sering muncul di tengah masyarakat, hal ini dapat terjadi karena pola makan dan menu makan yang salah. Penelitian ini bertujuan untuk mendeskripsikan tentang masalah kesehatan keluarga terutama dalam mencegah terjadinya obesitas dan penanganannya di lingkungan JL.Tapian Nauli NO37A Kel.Teladan Barat. Observasi masalah kesehatan ini berkaitan tentang bahaya obesitas. Penelitian dilakukan dengan metode observasi (pengamatan) .Penganalisaan data dilakukan dengan pengumpulan data yang kemudian dilakukan pemilahan data serta mengklasifikasi data yang akhirnya menyajikan hasil dari observasi. Kesimpulan keluarga binaan sudah mengetahui dan paham  tentang bahaya dan cara penjegahan obesitas sebelum diberikan edukasi  sudah banyak.
Application of Autologous Mesenchymal Stem Cells in Various Diseases: A Systematic Review hariaji, ilham
Buletin Farmatera Vol 7, No 2 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v7i2.9650

Abstract

Abstract:The use of mesenchymal stem cells (MSCs) to cure various diseases has become more widespread. Various clinical trials have been reported, both at level 1 and level 4. This systematic literature study aims to find out what diseases have been treated with autologous mesenchymal stem cells.This study is a systematic literature study by conducting literature searches in national and international journals in the last five years using the Google Scholar application using a systematic study method with the help of prism diagrams and classification tables to facilitate search.From the search results, 24 papers were obtained that were included in the inclusion criteria. The results of this study found that the use of MSCs as an alternative in the treatment of diseases has been very much carried out in clinical trials, where most of the results of these studies show a good level of safety, and can provide improvements histologically and physiologically, although in some diseases further research must be carried out to obtain consistent results.Keywords: Mesenchymal Stem Cells, MSCs, Autologous
Potensi Jus Buah Pare (Momordica Charantia L.) dalam Menurunkan Kadar Trigliserida pada Tikus Galur Wistar yang Diinduksi Diet Tinggi Lemak Rindi Ariska Silalahi; Ilham Hariaji
The Journal General Health and Pharmaceutical Sciences Research Vol. 2 No. 4 (2024): December : The Journal General Health and Pharmaceutical Sciences Research
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/tjghpsr.v2i4.476

Abstract

Hypercholesterolemia is one of the main factors that contribute to the development of life-threatening cardiovascular diseases. Bitter melon (Momordica charantia L.) is known to contain antioxidant compounds that have the potential to reduce cholesterol and triglyceride levels, making it an alternative natural treatment for hyperlipidemia. This study aims to evaluate the effectiveness of bitter melon juice in reducing triglyceride levels in Wistar rats induced by high-fat feed. This study used a true experimental design with a pretest-posttest with control group design. A total of 24 Wistar rats were induced with high-fat feed and divided into four groups: negative control, positive control, treatment group 1 (given bitter melon juice 1.8 mL), and treatment group 2 (given bitter melon juice 2.7 mL). Data analysis was performed using paired t test... A significant decrease in triglyceride levels was found in the groups given bitter melon juice 1.8 mL (p < 0.003) and 2.7 mL (p < 0.001) compared to the control group. Higher doses showed greater effectiveness in reducing triglyceride levels... Bitter melon (Momordica charantia L.) juice was shown to be effective in reducing triglyceride levels in Wistar rats induced by high-fat diet. These findings support the potential of bitter melon as a natural intervention to manage hyperlipidemia..
Prevalence of Allergies Due to Paracetamol Use in Children: A Literature Study Hariaji, Ilham
Buletin Farmatera Vol 9, No 3 (2024)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v9i3.23436

Abstract

Abstract: Paracetamol is an antipyretic and analgesic drug that is often used to relieve fever and pain in children. Although considered safe, the use of paracetamol in children can cause allergic reactions. This study aims to assess the prevalence of allergies due to the use of paracetamol in children. This Literature Review identifies and analyzes articles published in the last five years, using databases such as PubMed, Scopus, and Google Scholar. The included studies were studies with cohort, cross-sectional, and case-control designs that assessed the association between paracetamol use and allergic reactions in children. Of the 23 articles that met the inclusion criteria, it was found that the prevalence of allergies due to paracetamol use in children varied between 0.1% and 6.5%. Some of the factors that play a role in increasing the risk of allergies are the history of allergies in the family and the influence of environmental factors. In addition, frequently reported types of allergies include urticaria, eczema, and anaphylactic reactions. The results of this review suggest that although the prevalence of paracetamol allergy in children is relatively low, special attention is still needed, especially in children with a history of allergies or certain medical conditions. Proper management and further understanding of the pathogenesis of paracetamol allergy in children need to be done. Allergies due to paracetamol use in children, although rare, should remain a medical concern. Further research is needed to identify clearer risk factors and to develop guidelines for the use of paracetamol in children who have allergic predispositions.
Effectiveness of Metformin in Management Latest Type 2 Diabetes Mellitus : A Literature Study Hariaji, Ilham
Buletin Farmatera Vol 10, No 2 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i2.26247

Abstract

Abstract: Diabetes mellitus type 2 (DMT2) is a chronic metabolic disease whose prevalence is increasing globally. Metformin remains a first-line therapy due to its effectiveness in lowering blood glucose and its good safety profile. This literature review analyzed 25 publications from the journal Scopus Q1 (2021–2025) that evaluated the effectiveness of metformin in monotherapy and combination therapy. The studies analyzed included randomized controlled clinical trials, meta-analyses, and cohort studies. Metformin showed an average HbA1c decrease of 1.0–1.5%. Combination with SGLT2 inhibitors and GLP-1 receptor agonists improves glycemic control and lowers cardiovascular risk. Anti-inflammatory and endothelial protective effects have also been reported. Metformin remains relevant as the primary therapy, but its effectiveness increases when combined with new agents and adapted to the characteristics of the patient. Metformin is effective in the management of current DMT2, especially in combination therapy and personalization approaches.
Co-Authors Adinda Shafira ALZA HAMONANGAN PASARIBU Ance Roslina Anggi Yulisna Frisilia Saputri ARIL RIZALDI ASMAUL HABIBI AYUDYA, RINDA Bakhreni, Neyla Fitri ELMAN BOY Fadly Zahran Fani Ade Irma Fauzio, Revo Filza Amalia Putri FIRSTY DWI HIDAYATI SIRAIT Fitriani, Mutiara Frisilia Saputri, Anggi Yulisna Gurusinga, Nabira Maharani Humairah Medina Liza Lubis Jannah, Rhadatul KHAIRATUN NISA Linda, Putri Cici LUKMAN HAKIM ROMA MORA SIREGAR M. BIOMED Manurung, Muhammad Akbar MERY MARLINA HSB Muhammad Fadhly Zahran Muhammad Iqbal Prayoga Murtanto, Dita Fazhari Nabila, Windy Nabira Maharani Gurusinga Namora Harahap, Asra Dewita Nasution, Muhammad Rizki Ramadhan Bagaskara Neyla Fitri Bakhreni Prayoga, Muhammad Iqbal Putri, Rania Gusmi Rafika Baradarkhasan Zega Rania Gusmi Putri Revo Fauzio Rhadatul Jannah Rindi Ariska Silalahi Rizky Kurniawan Saidatul, Emma Dalen Sari Juliana Ariska Shafira, Adinda Shalin, Fonda Azarine SILALAHI, RINDI ARISKA SUKMA DWI KARTIKA Tambunan, Laila Nazmi Tosy Arna Dalimunthe Windy Nabila Yenita Yenita Zahran, Fadly