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Perjalanan Dakwah Rasulullah SAW dari Makkah ke Madinah Sintia Yulianti; Jeski Maulana; Widia Wiska; Ega Nasyifa; Wismanto Wismanto; Fitria Mayasari
Reflection : Islamic Education Journal Vol. 2 No. 1 (2025): Reflection : Islamic Education Journal
Publisher : Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/reflection.v2i1.377

Prophet Muhammad SAW, was a religious leader and state leader who had a commendable personality. He is the best role model (uswatun hasanah) for Muslims throughout the Islamic world. Through the Islamiyah da'wah organization, the Prophet was able to change the course of history and greatly influence the development of Islamic broadcasting from the jahiliyah (pre-Islamic) era to the era of Islamic civilization. The mission of Rasulullah SAW during the Mecca to Medina period was aimed at forming a pluralistic Muslim personality (in Mecca) as an absolute element of building an Islamic government in Medina where the community of Medina residents was plural. Pluralism in Medina was reflected in the existence of differences in religion, ethnicity and class and to create tolerance between each other through the Islamic da'wah organization. The Prophet's success in building a government was marked by the creation of the Medina charter as a law that regulated the plural community of Medina residents. This was despite his efforts in fighting for and preaching Islam, so that he was known as a highly respected Messenger and received sympathy from Muslims in Mecca - Medina at that time and the Islamic world in general. This study aims to reveal the events of the Prophet Muhammad's migration, the factors that caused it, its impacts, and the lessons that contributed to the formation of Islamic society. The research method used in this research is the method This descriptive study uses literature as a data collection tool. The analysis used is data reduction, data presentation, and drawing conclusions. The results of this research show; (1) That in the da'wah journey there are strategies so that the da'wah conveyed can be accepted, (2) the importance of knowing the important elements in da'wah activities to describe the journey of the Prophet's da'wah according to Islamic history (Mecca - Medina period).

Konsep Keadilan dan Perdamaian Dalam Islam Adityo Dapi Pratama; M. Thoriqul Haq; Fadil Zalfa Firmansyah; Wafi Hidayat; Wismanto Wismanto; Fitria Mayasari
Reflection : Islamic Education Journal Vol. 2 No. 1 (2025): Reflection : Islamic Education Journal
Publisher : Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/reflection.v2i1.378

The concepts of justice and peace in Islam are fundamental elements that underlie the social, political and moral structure in Islamic society. Justice (al-'Adl) in Islam includes not only legal or distributive justice, but also social and spiritual justice which demands a balance between individual rights and collective interests. This research aims to provide a deeper understanding of the importance of these two concepts in creating a harmonious and civilized society, as well as how Muslims can contribute to creating a better world. This research is descriptive-analytic in nature, namely describing and analyzing in depth how Islam views justice and peace based on available sources. Following are the research steps: Determine the main research theme (justice and peace), collect data sources, read and analyze relevant texts, identify Islamic principles related to justice and peace. These principles of justice are strengthened by the teachings of the Koran and Sunnah which emphasize the importance of equal treatment, eliminating injustice and fulfilling human rights. Peace (as-Salam) in Islam is not only interpreted as the absence of conflict, but as a state of harmony rooted in justice and a sense of social responsibility. This research can provide deeper insight into the concept of justice in Islam. Islam teaches that justice is not only applied in the context of human relationships with God, but also in relationships between humans. This research can examine how these principles of justice can be applied in various contexts of daily life, including government, economics and social relations.

Beyond Co-Expression: Unraveling the Complex Relationship Between PD-L1 and Tumor-Infiltrating Lymphocytes in Basal Cell Carcinoma Subtypes Fitria Mayasari; Kenty Wantri Anita; Diah Prabawati Retnani; Rachmad Sarwo Bekti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 8 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i8.1354

Background: Basal cell carcinoma (BCC) is the most prevalent non-melanoma skin cancer, characterized by high recurrence rates. Immunotherapy, particularly targeting the Programmed Death-1 (PD-1)/Programmed Death-Ligand 1 (PD-L1) axis, offers a promising therapeutic avenue. The interplay between PD-L1 expression on tumor and immune cells and the nature of Tumor-Infiltrating Lymphocytes (TILs) is crucial for immune response, yet their relationship in BCC, especially across diverse histological subtypes, remains incompletely understood. This study aimed to investigate the correlation between PD-L1 expression and TILs density in various BCC subtypes, seeking to elucidate the complexities of their interaction within the tumor microenvironment. Methods: This analytical observational study utilized a cross-sectional design, analyzing 20 archived paraffin-embedded BCC tissue samples from Dr. Saiful Anwar Regional General Hospital Malang. PD-L1 expression was assessed by immunohistochemistry using the 22c3 clone and evaluated via the Combined Positive Score (CPS). TILs were semi-quantitatively assessed as percentage infiltration and categorized into low, moderate, and high grades. Histological subtypes of BCC were documented. Spearman correlation was used to analyze the relationship between PD-L1 expression and TILs. Results: Of the 20 BCC cases, 55% exhibited PD-L1 positivity (CPS ≥ 1). TILs infiltration was predominantly moderate (70%), with 25% high and 5% low. The cohort included nodular (40%), infiltrating (35%), and basosquamous (25%) as the main subtypes, with specific variants also analyzed. Basosquamous BCC consistently showed positive PD-L1 expression (100% of its cases positive), while nodular and infiltrating subtypes displayed varied PD-L1 expression. TILs distribution also varied across subtypes, with nodular BCC exhibiting the full range from low to high TILs. Overall, no significant correlation was observed between PD-L1 expression and TILs density (Spearman's r = -0.077, p = 0.747). Conclusion: This study confirms PD-L1 expression and TILs presence in BCC but reveals no direct linear correlation between them across the cohort, even when considering broad subtypes. Basosquamous BCC consistently expressed PD-L1. The lack of overall correlation suggests a complex, potentially subtype-specific interplay within the BCC tumor microenvironment, warranting further investigation into functional TILs subsets and other immune modulators.

Beyond Co-Expression: Unraveling the Complex Relationship Between PD-L1 and Tumor-Infiltrating Lymphocytes in Basal Cell Carcinoma Subtypes Fitria Mayasari; Kenty Wantri Anita; Diah Prabawati Retnani; Rachmad Sarwo Bekti
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 8 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i8.1354

Background: Basal cell carcinoma (BCC) is the most prevalent non-melanoma skin cancer, characterized by high recurrence rates. Immunotherapy, particularly targeting the Programmed Death-1 (PD-1)/Programmed Death-Ligand 1 (PD-L1) axis, offers a promising therapeutic avenue. The interplay between PD-L1 expression on tumor and immune cells and the nature of Tumor-Infiltrating Lymphocytes (TILs) is crucial for immune response, yet their relationship in BCC, especially across diverse histological subtypes, remains incompletely understood. This study aimed to investigate the correlation between PD-L1 expression and TILs density in various BCC subtypes, seeking to elucidate the complexities of their interaction within the tumor microenvironment. Methods: This analytical observational study utilized a cross-sectional design, analyzing 20 archived paraffin-embedded BCC tissue samples from Dr. Saiful Anwar Regional General Hospital Malang. PD-L1 expression was assessed by immunohistochemistry using the 22c3 clone and evaluated via the Combined Positive Score (CPS). TILs were semi-quantitatively assessed as percentage infiltration and categorized into low, moderate, and high grades. Histological subtypes of BCC were documented. Spearman correlation was used to analyze the relationship between PD-L1 expression and TILs. Results: Of the 20 BCC cases, 55% exhibited PD-L1 positivity (CPS ≥ 1). TILs infiltration was predominantly moderate (70%), with 25% high and 5% low. The cohort included nodular (40%), infiltrating (35%), and basosquamous (25%) as the main subtypes, with specific variants also analyzed. Basosquamous BCC consistently showed positive PD-L1 expression (100% of its cases positive), while nodular and infiltrating subtypes displayed varied PD-L1 expression. TILs distribution also varied across subtypes, with nodular BCC exhibiting the full range from low to high TILs. Overall, no significant correlation was observed between PD-L1 expression and TILs density (Spearman's r = -0.077, p = 0.747). Conclusion: This study confirms PD-L1 expression and TILs presence in BCC but reveals no direct linear correlation between them across the cohort, even when considering broad subtypes. Basosquamous BCC consistently expressed PD-L1. The lack of overall correlation suggests a complex, potentially subtype-specific interplay within the BCC tumor microenvironment, warranting further investigation into functional TILs subsets and other immune modulators.

Fear of Missing Out (FOMO) and Scarcity Strategies: A Qualitative Exploration of Consumer Communication with Flash Sales on E-Commerce Platforms Fitria Mayasari; Nurrahmi; Salsabila, Fahmi
Jogjakarta Communication Conference (JCC) Vol. 3 No. 1 (2025): The 6th Jogjakarta Communication Conference (JCC)
Publisher : Jogjakarta Communication Conference (JCC)

Show Abstract | Download Original | Original Source | Check in Google Scholar

This research investigates the impact of the psychological concept of Fear of Missing Out (FOMO) and scarceness marketing strategies on consumer interactions and behaviors during ecommerce flash sales. A qualitative approach was selected to delve into emotions, experiences, and cognitive aspects of decision-making through in-depth interviews with active online shoppers. Results show that FOMO is linked to an increase in feelings of volatility and escalation, which encourages greater and more rapid emotion-laden purchasing behavior that is not thoroughly reasoned out. Countdown clocks and limits on available stock are scarcity strategies that increase the intensity of value placed on the items which make them more desirable and exclusive. Furthermore, the study revolves around consumers’ perception of flash sales—extensively shared on social media and other peer networks—illustrating that their personal and social narratives often fuel a collective feeling of urgency. This underscores powerful intersectional dynamics of modern corporate marketing strategies and consumer behavior vis-a-vis the approaches that need to be adopted, especially from an ethical standpoint, in e-commerce business systems.

Manusia Dalam Islam: Antara Akal, Ruh dan Nafsu Rica Khairunisa; M.Rizki Mayollie; Carenina Br.Siagian; Dzaky Fadhlu Rahman; Fitria Mayasari; Wismanto Wismanto
Karakter : Jurnal Riset Ilmu Pendidikan Islam Vol. 2 No. 1 (2025): Februari : Karakter : Jurnal Riset Ilmu Pendidikan Islam
Publisher : Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/karakter.v2i1.363

This article discusses the role of reason, spirit and passion in human life according to Islamic teachings, and how these three elements interact with each other to achieve a balanced life. The purpose of this research is to understand how Islam teaches the management of reason, spirit and passion as fundamental elements in human life, so that true happiness in this world and the hereafter can be achieved. The method used in this research is literature review and text analysis of the main sources of Islam, such as the Qur'an and Hadith, as well as the opinions of relevant scholars and experts. The results of this study show that Islam emphasizes the importance of maintaining harmony between reason, spirit, and lust through worship, introspection, and self-control. The intellect functions as a tool for wise thinking and decision-making, helping humans understand religious teachings and controlling passions. The spirit as the spiritual essence connects humans with God, providing the impetus to do good and achieve spiritual happiness. Meanwhile, lust, which includes worldly urges, must be controlled so as not to lead humans to pleasures that violate sharia. The study concludes that the balance between these three elements leads to a meaningful life that is in line with the purpose of creation as servants of Allah.

Menelusuri Hukum Islam: Peran Al Qur’an Dalam Pembentukan Norma Hukum Rafha Adha Abiyutama; Arif Septian Marta; Rafif Weno Putra; Muhammad Haikal; Robby Ichsan; Fitria Mayasari; Wismanto Wismanto
Karakter : Jurnal Riset Ilmu Pendidikan Islam Vol. 2 No. 1 (2025): Februari : Karakter : Jurnal Riset Ilmu Pendidikan Islam
Publisher : Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/karakter.v2i1.366

Law that is just and in line with social values adopted by society. This role is increasingly relevant in facing modern challenges, where understanding and application of the teachings of the Qur'an have an important role in the formation of legal norms in Muslim society. As a holy book, the Qur'an provides moral and ethical guidelines that form the basis for the Islamic legal system. Through its various verses, the Qur'an establishes the principles of justice, goodness, and social responsibility that influence individual behavior and interactions between members of society. The purpose of this study is to explore the values of Islamic law related to the role of the Qur'an in the formation of legal norms. The method used in this study is a qualitative method, by making books, magazines, articles and journals related to the research theme to collect data, then codify it, and then describe it in this article. The results of this study indicate that the application of Islamic law is largely determined by the Qur'an and Sunnah. Laws taken from sources other than the Qur'an and Sunnah will not last long, because the law is made by humans. So that potentially whoever is in power is the one who determines the law. In addition, the Qur'an also provides concrete rules regarding aspects of life, such as marriage, inheritance, and crime, which are then interpreted and applied in the context of sharia law. Thus, the Qur'an not only functions as a spiritual source, but also as a basis for the formation of norms that need to be adjusted to social dynamics and developing legal needs.

Aqidah dan Etika: Membangun Moralitas di Tengah Perubahan Sosial Nashirah Dwi Arini Faiza; Tia Angrelia; Siti Nuriyah Ahmad; Risya Purnama Sari; Fitria Mayasari; Wismanto Wismanto
Karakter : Jurnal Riset Ilmu Pendidikan Islam Vol. 2 No. 1 (2025): Februari : Karakter : Jurnal Riset Ilmu Pendidikan Islam
Publisher : Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/karakter.v2i1.368

The background of this study is the increasingly rapid social, cultural, and technological changes that have an impact on the dynamics of morality in society. In the midst of these changes, aqidah (belief) and ethics become important foundations in building solid morality. However, the main challenge faced is how to maintain the relevance of the teachings of aqidah and ethics in the context of modern life that continues to develop. This study aims to analyze the role of aqidah and ethics in shaping individual and collective morality amidst changing times. The main objective is to understand how religious beliefs and ethical principles can be applied effectively in maintaining moral integrity amidst the rapid flow of global change. The method used in this study is a qualitative method with analysis carried out by looking at the relationship between the values of aqidah, ethics, and morality in everyday life. The results of the study show that aqidah and ethics have an important role in shaping resilient morality amidst change. A deep understanding of aqidah and the application of ethical principles have proven to be a foundation for society to maintain positive moral values. However, the results also show that adaptation and renewal in the approach to teaching aqidah and ethics are needed to be more relevant and accepted by the younger generation living in the digital era.

Membedah Syirik : Bahaya Tersembunyi Yang Mengancam Umat Manusia Arimbi Pramesty; Audyni Khalisyah; Delima Delima; Farah Madina; Fitria Mayasari; Wismanto Wismanto
Karakter : Jurnal Riset Ilmu Pendidikan Islam Vol. 2 No. 1 (2025): Februari : Karakter : Jurnal Riset Ilmu Pendidikan Islam
Publisher : Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/karakter.v2i1.369

Shirk, the sin of associating partners with Allah, poses a significant threat to the foundation of faith among Muslims. In the Qur'an, shirk is described as the greatest sin that will not be forgiven except through sincere repentance. This article aims to explore the concept of shirk, define its various forms, and provide examples of major (akbar) and minor (ashgar) shirk. Using a qualitative approach, this research analyzes Islamic literature and Qur'anic verses to examine the impact of shirk on the spiritual and moral lives of Muslims. The findings indicate that shirk can damage an individual's relationship with Allah and threaten moral integrity. In modern contexts, shirk may also manifest in subtle forms, such as materialism. Education on Tawhid, emphasizing the oneness of Allah, is crucial in preventing shirk. This study seeks to raise awareness about the dangers of shirk and the importance of maintaining pure faith. With a better understanding of shirk, it is hoped that individuals can avoid such practices and align their lives with Islamic teachings.

Media Literacy and Digital Privacy Management among Indonesian University Students on Social Media Nazhifah; Aidil Haris; Fitria Mayasari; Dony Rano Virdaus; Andhita Risko Faristiana
INJECT (Interdisciplinary Journal of Communication) Vol. 11 No. 1 (2026)
Publisher : FAKULTAS DAKWAH UIN SALATIGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18326/inject.v11i1.6013

This study aims to determine how proficient students at the University of Muhammadiyah Riau are in using technology and managing the privacy of their communication on social media, considering online crimes and potential misuse of personal data. Using a descriptive purposive sampling technique. The results show that students possess good digital literacy in maintaining communication privacy and security on social media. They demonstrate awareness of digital, ethical, security, and cultural components that support responsible digital behavior, indicating that these literacy dimensions are effectively implemented in managing students’ privacy and digital footprint.

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