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Hepatic Cirrhosis: A Literature Review Dewi, Komang Puspa; Abida, Aisya Nur; Aswandani, Alifa; Anggraeni, Baiq Annisa Ulfi; Shofa, Dhiya Atsila; Aunurrahman, Muhammad Rezky Audia; Husna, Najla Firyal
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7801

Abstract

Hepatic cirrhosis is a chronic liver disease characterized by fibrosis and regeneration of nodules in the liver, which if it occurs for a long time, hepatocyte cells will be damaged so that they cannot function again, potentially threatening life. The prevalence of incidence and mortality depends on the progression of hepatic cirrhosis, which is influenced by the patient's etiology and treatment. The purpose of writing this article is to provide new insight into the importance of understanding the risk factor and causes of hepatic cirrhosis. This study uses a literature review approach by collecting data from online databases including Google Scholar, ProQuest, MDPI, and PubMed to search for articles discussing “Hepatic Cirrhosis”. Early detection based on clinical manifestations and appropriate treatment can reduce mortality and prevent complications that may worsen the patients condition.
Deep Vein Thrombosis (DVT): A Literature Review Kamila, Alya Syafa; Ginuluh, Gintis Dhimar; Syakir, Syahda Aqila; Abida, Aisya Nur; Balqis, Ananda Amirah; Karlina, Fairuz; Murniatin, Rinesita; Farras, Afif; Raihan, Al Fikar; Putra, Rian Akka Jaya; Arsyatt, Maz Isa Ansyori
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8008

Abstract

Deep Vein Thromboembolism (DVT) occurs due to the formation of blood clots in the veins, characterized by the formation of thrombi along with an inflammatory response in the inner walls of the veins. DVT most commonly occurs in the deep veins of the lower extremities but can also occur, albeit less frequently, in other areas such as the arms or other forms of superficial thrombosis. This article aims to review the epidemiology, clinical presentation, diagnosis, pathophysiology, and management of deep vein thrombosis. The literature review was conducted by searching for relevant articles on deep vein thrombosis published in the past fifteen years. Literature searches were performed using Google Scholar, PubMed, and NCBI databases. The findings highlight the clinical manifestations of DVT and its potential to cause serious complications, particularly post-thrombotic syndrome. Post-thrombotic syndrome is a debilitating condition that can significantly impair patients' quality of life. Management of DVT involves both pharmacological and non-pharmacological treatments. Understanding the mechanisms of deep vein thrombosis and its management is crucial in minimizing the complications associated with this condition.
Factors Affecting the Quality of Life of Children with Thalassemia: Literature Review Abida, Aisya Nur
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8143

Abstract

The chronic condition known as thalassaemia is a hereditary ailment that results in the loss or decreased synthesis of one or more globin chains in erythrocytes. Ineffective erythropoiesis, early erythrocyte breakdown, and anaemia are all possible outcomes of thalassaemia. In Indonesia, it is estimated that between 3-10% of people have β thalassaemia, whereas between 2.6-11% have α thalassaemia. Approximately 2,500 newborns are thought to be born with β-thalassemia major each year. The purpose of this study is to identify the variables that affect the quality of life for kids with thalassaemia so that the right kind of medication can be developed to lessen this issue. This study used the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) technique to conduct a literature review. The PubMed and ScienceDirect databases were used to conduct online searches for the literature. Three articles in all were chosen for examination based on search results that satisfied the inclusion requirements. The study findings from the three analysed publications indicate that the primary factor influencing a child's declining quality of life is school function. Children's age, the kind of iron chelation treatment, the frequency of transfusions, the number of family members with thalassaemia, and haematopoietic stem cell transplant operations are all factors that affect the quality of life of patients with thalassaemia. Based on the factors that influence the quality of life of children with thalassemia, the role of parents supported by the government and community is needed in the treatment of children with thalassemia.