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Uji Efek Ekstrak Collagen Spons Laut (Stylissa flabeliformis) Terhadap Profil Kulit Mencit Sunarwidhi, Anggit Listyacahyani; Deccati, Rizqa Fersiyana; Maulana, Farreh Alan; Utami, Ni Wayan Putri; Dewi, Ni Made Amelia Ratnata
Jurnal Promotif Preventif Vol 7 No 4 (2024): Agustus 2024: JURNAL PROMOTIF PREVENTIF
Publisher : Fakultas Kesehatan Masyarakat Universitas Pancasakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Indonesia merupakan negara dengan biodiversitas tinggi termasuk biota lautnya. Spons laut merupakan sumber alami yang dapat ditemukan dalam jumlah melimpah di perairan Indonesia dan mengandung berbagai komponen bioaktif termasuk collagen yang bermanfaat untuk kesehatan kulit. Pada penelitian ini, dilakukan suatu studi efek ekstrak collagen dari spons laut Stylissa flabelliformis terhadap profil kulit mencit (Mus musculus L.). Spons laut tersebut diambil dari perairan Lombok Utara Indonesia kemudian ekstraksi collagen dilakukan dengan menggunakan Tris-HCl Buffer diikuti dengan pengendapan collagen menggunakan asam asetat. Selanjutnya dilakukan karakterisasi ekstrak collagen dengan menggunakan FTIR-Spectroscopy. Studi efek ekstrak collagen terhadap profil mencit dilakukan selama 14 hari. Hasil penelitian ini menunjukkan bahwa pemberian ekstrak collagen spons laut Stylissa flabelliformis secara topikal ini dapat meningkatkan kadar minyak (sebum) dan kelembapan kulit (moisture), meskipun tidak signifikan. Sedangkan elastisitas kulit dan kandungan collagen kulit tidak terpengaruh. Dapat disimpulkan bahwa penggunaan ekstrak collagen ini dapat memperbaiki profil kelembapan kulit, sehingga dapat dikembangkan sebagai pelembap alami.
Metabolite Profile of Marine Sponge (Stylissa sp.) Lipid Extract and Its Effect on Bacterial Skin Infection Maulana, Farreh Alan; Utami, Ni Wayan Putri; Handayani, Ervina; Kabir, Mila Mayanti; Inggit, Baiq Putri Maharani Bine; Pangestu, Kukuh Waseso Jati; Deccati, Rizqa Fersiayana; Dewi, Ni Made Amelia Ratnata; Sunarwidhi, Anggit Listyacahyani
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7848

Abstract

UV radiation from sunlight can induce the formation of free radicals, which can disrupt cellular homeostasis or DNA by triggering inflammatory signal transduction. The occurrence of inflammation in the skin can be aggravated by the presence of the bacterium Staphylococcus aureus. Previous studies have shown that the marine sponge Stylissa sp. contains an abundance of fatty acids and lipids compared to other species. Although Stylissa sp. has great potential for health applications, research on the bioactivity of lipid and fatty acid compounds from this sponge remains limited. Therefore, this study aims to explore the lipid content of Stylissa sp. as an alternative source of antibacterial agents against pathogens responsible for photoaging. The metabolite profiling of the extract was conducted using GC-MS, while the antibacterial activity was performed using the Kirby-Bauer method. Based on GC-MS profiling results, six compounds were identified in the lipid extract of Stylissa sp. namely palmitic acid, butyl glycol acetate, n-eicosylcyclohexane, isopropyl laurate, oleic acid, and 1-tetradecanol. Antibacterial evaluation of Stylissa sp. lipid extract at concentrations of 25%, 75%, and 100% showed antibacterial activity against Staphylococcus aureus, with inhibition zone diameters of 1.83, 2.17, and 2.92 mm, respectively. The results in this study have shown that the lipid extract of Stylissa sp. contains lipid compounds with potential anti-bacterial activity towards S. aureus. Future research to isolate unsaturated fatty acid compounds from the lipid extract of Stylissa sp. to achieve higher antibacterial activity is recommended.
SOSIALISASI WAWASAN KESEHATAN DASAR PADA SISWA SD MELALUI PROGRAM KULIAH KERJA NYATA INTERNASIONAL (KKN UNIVERISTAS MATARAM-FUKUSHIMA MEDICAL UNIVERSITY JEPANG) DI DESA PUYUNG KABUPATEN LOMBOK TENGAH Haqiqi, Nirwana; Qoriasmadillah, Wanda; Fitriani, Fitriani; Utami, Ni Wayan Putri; Ichfa, Muh Syach Maulad; Arrazy, Muadz; Tate, Kazuma; Shinozuka, Miho; Ikunaga, Arisa; Miyake, Masao; Hazama, Akihiro; Prasedya, Eka Sunarwidhi
Jurnal Abdi Insani Vol 11 No 2 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i2.1471

Abstract

Rapid population growth has caused Indonesia to experience various population problems. One of the problems that often occurs at this time is health problems. West Nusa Tenggara (NTB) is a province that has the highest percentage of child morbidity in Indonesia at 21.30%. Puyung Village is a village in Jonggat Sub-district that has the largest population of 13,648 people. Based on this number, Puyung Village has diverse population problems, namely health problems in children. Through socialization and education activities carried out by KKN International students, it is hoped that it will become a forum for increasing the level of knowledge about basic health and can form good relationships between the parties involved. The intended targets in this activity are elementary school students at SD-IT Yayasan GMC and SDN 1 Puyung. The subject matter provided is the introduction of the body's organ structure, the dangers of smoking, nutritional balance and clean and healthy living behavior (PHBS). The socialization and education activities regarding health insights for elementary school students in Puyung Village were classified as successful. The parameters of success in this activity can be seen and measured based on student responses to the material provided. The questions asked by students were quite diverse and the ability of students to answer questions given by students before and after the activity increased. In addition, students who take part in this program receive the material with a happy feeling because the provision of material is done in a fun way through playing and learning using learning models that have interesting shapes, colors and mechanisms. This activity was successfully carried out because the objectives were achieved well. Thus students can apply what they have learned in their lives.
PENYULUHAN PENANAMAN DAN PEMANFAATAN TANAMAN OBAT KELUARGA (TOGA) SEBAGAI JAMU TRADISIONAL MASYARAKAT DESA SENGKOL Ichfa, Muhammad Syach Maulad; Maulana, Farreh Alan; Utami, Ni Wayan Putri; Handayani, Ervina; Fitriani, Fitriani; Hikmaturrohmi, Hikmaturrohmi; Haqiqi, Nirwana; Saraswati, Putu Bella Aprillia; Nurhidayati, Siti Zainiah; Qoriasmadillah, Wanda; Arrazy, Mu'adz; Ramadhan, Moch. Fitrah; Prasedya, Eka Sunarwidhi
Jurnal Abdi Insani Vol 11 No 2 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i2.1472

Abstract

Indonesia is a country rich in natural resources with 30,000 species of plants that have the potential as medicines from a total of 40,000 plant species in the world. Most Indonesians have home yards, but still few are managed productively by planting TOGA. The large area, the large number of hamlets, and the dense population cause various problems in Sengkol Village, one of which is the lack of understanding about the importance of planting and utilizing TOGA. Therefore, it is necessary to conduct counseling on the importance of planting TOGA in the yard and demonstration of the use of TOGA into traditional herbal medicine as an alternative treatment with low costs and low side effects. Counseling and demonstrations in this activity are carried out by lecture and discussion methods, as well as product demonstrations. The lecture method is carried out when delivering counseling materials, the discussion method is carried out during the question and answer session, and the product demonstration method is carried out when demonstrating the making of herbal medicine from TOGA. The location of TOGA planting was carried out on an empty land in the yard of one of the residents of Pampang Lauk Hamlet with a land size of 6x6 m2. TOGA that is planted has properties that are adapted to diseases that commonly occur in the community, namely yellow turmeric, white turmeric, ginger, ginger, galangal, kencur, katuk, virgin palm, lemongrass, betel. Making a green house was carried out for one week involving youth and villagers using bamboo and paranets. Counseling participants were dominated by men (66.6%), adolescents (57.57%), and students (42.42%). The material presentation, discussion, and demonstration sessions went smoothly and the community was very enthusiastic about participating in the activity. Based on the counseling that has been carried out, the urgency of planting TOGA in the yard and the use of TOGA as an alternative treatment is well conveyed.