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All Journal Jurnal Agrotek UMMat Jurnal Farmasi Higea Acta Chimica Asiana Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Promotif Preventif Jurnal Ilmiah Abdi Mas TPB Unram Jurnal Farmasi dan Sains Indonesia (JFSI) INDRA: Jurnal Pengabdian kepada Masyarakat Journal of Agritechnology and Food Processing Jurnal Pepadu
Deccati, Rizqa Fersiyana
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Pembuatan Paper Kit Test Ekstrak Etanol Bunga Telang (Clitoria ternatea L.) Untuk Identifikasi Formalin Pada Makanan Suryadnyani, Ni Made Detia; Ananto, Agus Dwi; Deccati, Rizqa Fersiyana
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 2, No 2 (2021): JULI
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v2i2.5149

Abstract

ABSTRAKTemuan makanan berformalin di Indonesia khususnya provinsi NTB masih dijumpai. Analisa makanan berformalin membutuhkan biaya yang mahal sehingga tidak terjangkau untuk semua kalangan. Ekstrak etanol bunga telang (Clitoria ternatea L.) berpotensi sebagai indikator formalin pada makanan. Penelitian ini bertujuan untuk membuat paper kit test ekstrak etanol bunga telang untuk identifikasi formalin pada makanan. Teknik pembuatan paper kit test adalah dengan immobilisasi reagen dengan cara merendam paper kit test ke suatu reagen. Ekstrak etanol bunga telang dan dalam bentuk paper kit test dilakukan uji pada dua kelompok kontrol yaitu kontrol positif (sampel makanan berformalin) dan kelompok negatif (sampel makanan tanpa formalin). Hasil pengujian paper kit test dibandingkan dengan test kit formalin pasaran untuk melihat perbedaan hasil uji.  Interpetasi hasil dilihat berdasarkan perubahan warna pada ekstrak maupun paper kit test. Hasil positif ditunjukkan dengan perubahan warna dari biru gelap menjadi biru cerah. Pada penelitian ini diperoleh yaitu ekstrak etanol bunga telang mampu mendeteksi kandungan formalin pada makanan, sedangkan dalam bentuk paper kit test belum mampu mendeteksi karena tidak terabsorbsinya antosianin pada Whattman. Kata kunci : Formalin; Ekstrak bunga telang; Paper kit test.ABSTRACTFormalin’s foods in Indonesia, especially in the province of NTB are still found. Analysis of formalin’s food is expensive so it is not affordable for all people. Ethanol extract of butterfly pea (Clitoria ternatea L.) has potential as an indicator of formalin in food. The purpose of this research is to make paper kit test of butterfly pea ethanol’s extract to detect formalin in food. The technique of making a paper kit test is reagent’s immobilization by immersing the paper into a reagent. The extract and paper kit test were tested on two control groups, positive (food contains formalin) and the negative (food without formalin). The results of the paper kit test was compared with the formalin test kit on the market to see the difference in test results. The interpretation of the results was seen based on the color changes on both instrument. A positive result is indicated by a color change from dark blue to bright blue. In this study, the result shows that the ethanol extract was able to detect the formalin content in food, while the paper kit test was not able to detect because anthocyanin couldn’t absorbs in Whattman. Keywords : Formalin; ethanol extract of butterfly pea; paper kit test.  
WORKSHOP KETRAMPILAN DASAR LABORATORIUM SAINS DAN TEKNOLOGI UNTUK MENINGKATKAN DAYA SAING Ananto, Agus Dwi; Muliasari, Handa; Deccati, Rizqa Fersiyana
Jurnal Ilmiah Abdi Mas TPB Unram Vol 3, No 2 (2021): Edisi Juli 2021
Publisher : Fakultas Teknologi Pangan dan Agroindustri, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/amtpb.v3i2.73

Abstract

Rendahnya kemampuan dasar laboratorium menyebabkan seringya pengguna laboratorium melakuakn kesalahan dalam kegiatan di laboratorium. Hal ini diperparah dengan sedikitnya menu pemahaman ketrampilan laboratorium pada matakuliah dibidang sains dan teknologi. Salah satu upaya yang dapat dilakukan untuk meningkatkan kemampuan dasar laboratorium adalah dengan upaya melakukan pemahaman penggunaan bahan dan alat laboratorium. Pemahaman sasaran kegiatan tentang skill atau kemampuan dalam teknik laboratorium diharapkan menjadi lebih meningkat setelah mengikuti kegiatan ini. Kegiatan ini dilaksanakan melalui platform zoom dan live streaming youtube. Pada kegiatan ini dipaparkan teknik penggunaan, pencucian dan penyimpanan alat-alat gelas, penanganan bahan, dan penyimpanan bahan, aspek MSDS bahan dan penanganan limbah bahan kimia di laboratorium. Selain itu, pada kegiatan ini juga di demonstrasikan salah satu teknik laboratorium dalam hubungannya dengan konsep kromatografi. Hasil dari kegiatan ini diperoleh peningkatan pemahaman peserta terkait dengan kegiatan di laboratorium. Hal ini tercermin dari meningkatnya nilai peserta dalam mengerjakan soal sebelum dan sesudah mengikuti kegiatan ini. Rata-rata nilai sebelum kegiatan sebesar 89,67 meningkat menjadi 96,5 pada saat mengerjakan soal sesudah mengikuti kegiatan ini
EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN RAWAT INAP DENGAN METODE DDD (DEFINED DAILY DOSE)/ 100 PASIEN-HARI RAWAT DI RUMAH SAKIT UNIVERSITAS MATARAM TAHUN 2021 Putri, Enda Desideria; Hasina, Raisya; Andanalusia, Mahacita; Deccati, Rizqa Fersiyana; Dewi, Ni Made Amelia Ratnata
Jurnal Farmasi Higea Vol 16, No 2 (2024)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v16i2.601

Abstract

Adanya peningkatan prevalensi resistensi antibiotik di rumah sakit dapat disebabkan oleh penggunaan antibiotik yang kurang bijak dan berlebihan. Untuk mengatasi masalah ini, penting untuk menilai penggunaan antibiotik di rumah sakit. Penelitian ini bertujuan untuk mengevaluasi secara kuantitatif penggunaan antibiotik pada pasien rawat inap di Rumah Sakit Universitas Mataram. Penelitian ini menggunakan desain cross-sectional dengan pendekatan kuantitatif, dan pengumpulan data dilakukan secara retrospektif dengan memeriksa rekam medis tahun 2021. Populasi penelitian terdiri dari pasien rawat inap yang telah diberi resep antibiotik. Pemilihan pasien dilakukan dengan menggunakan teknik purposive sampling. Data penggunaan antibiotik diperoleh dari 121 rekam medis dan dianalisis secara deskriptif dengan metode ATC/DDD. Hasil penelitian menunjukkan bahwa ceftriaxone memiliki nilai kuantitas untuk dosis harian pasti (DDD) tertinggi sebesar 42,75 DDD/100 pasien-hari rawat, diikuti oleh cefixime sebesar 34,16 DDD/100 pasien-hari rawat, levofloxacin (IV) sebesar 20,93 DDD/100 pasien-hari rawat, dan azitromisin pada 15,05 DDD/100 pasien-hari rawat. Di antara seluruh antibiotik yang diperiksa pada penelitian ini, ceftriaxone memiliki nilai kuantitas DDD tertinggi per 100 hari pasien-hari rawat.
Review: analysis of optimal conditions of bovine serum albumin (BSA) protein denaturation inhibition method in anti-inflammatory activity testing of various plant leaf extracts Nirmala, Annisa Rizka; Permatasari, Lina; Muliasari, Handa; Deccati, Rizqa Fersiyana
Journal of Agritechnology and Food Processing Vol 3, No 2 (2023)
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jafp.v3i2.20953

Abstract

Inflammation is a manifestation of the immune response to eliminate antigens and a process to respond to tissue damage. There are various drugs to control and suppress inflammation, referred to as anti-inflammatory agents. One method to test anti-inflammatory activity is the inhibition of Bovine Serum Albumin (BSA) protein denaturation. This review article will discuss the stages and optimal conditions in the inhibition of BSA protein denaturation method using various leaf extract samples. Literature was gathered from several journal database websites such as PubMed, ScienceDirect, and Google Scholar with keywords "anti-inflammatory," "inhibition of BSA protein denaturation," and "leaf extract," spanning publication years from 2002 to 2023. The results of anti-inflammatory activity tests can be expressed as either percentage inhibition or IC50 values. Optimal conditions were obtained by preparing a 0.2% BSA solution with Tris Buffer Saline (TBS), maintaining a 9:1 composition ratio between the BSA solution and the sample, and heating at an optimal denaturation temperature of 70 °C. Before conducting tests using this method, it is crucial to ensure that the suspected active compounds with anti-inflammatory activity are not degraded at this heating temperature.
Uji Aktivitas Antioksidan Ekstrak Etanol dan Fraksi Etil Asetat Daun Renggak (Amomum dealbatum Roxb.) Dengan Metode ABTS Radiartini, Ni Nyoman; Andayani, Yayuk; Deccati, Rizqa Fersiyana
Jurnal Farmasi & Sains Indonesia Vol 7 No 2 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no2p143-152

Abstract

Renggak leaves (Amomum dealbatum Roxb.) contain secondary metabolites such as flavonoids, terpenoids, and tannins, which act as antioxidants. Previous research has shown that ethanol extract of renggak leaves has moderate antioxidant activity using the DPPH method. However, research on the antioxidant activity of the extract is limited, thus further investigation at the fraction level is needed. This study aims to identify the secondary metabolite content and antioxidant activity using the ABTS method (2,2-azinobis-3-ethylbenzothiazoline-6-sulfonic acid) of the ethanol extract and ethyl acetate fraction of renggak leaves. The renggak leaf samples were extracted using maceration with 96% ethanol (1:10), followed by fractionation with water, n-hexane, and ethyl acetate using a separatory funnel (1:1). Secondary metabolite screening was conducted on the ethanol extract and ethyl acetate fraction. Antioxidant activity was measured based on the reduction in absorbance at the ABTS maximum wavelength, expressed as IC50 (inhibitory concentration 50%) values, with ascorbic acid as a comparison. The secondary metabolite screening results indicated that both the ethanol extract and ethyl acetate fraction of renggak leaves contain alkaloids, flavonoids, tannins, and steroids. The antioxidant activity of the ethanol extract was very weak with an IC50 value of 236.11 ppm, whereas the antioxidant activity of the ethyl acetate fraction was strong with an IC50 value of 86,95 ppm, compared to the antioxidant activity of ascorbic acid with an IC50 value of 10,00 ppm.
Exploration of secondary metabolite profile in the n-hexane fraction of Rhizophora mucronata, Avicennia marina, and Sonneratia alba Maziya, Raehanul; Permatasari, Lina; Deccati, Rizqa Fersiyana; Muliasari, Handa; Rahman, Fania; Annas, Zulfiana Fatianingrum; Sammanta, Rahula Vijja
Acta Chimica Asiana Vol. 8 No. 1 (2025)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v8i1.231

Abstract

Indonesia is a maritime and archipelagic country with an ocean area of almost two-thirds of its total area, with a coastline stretching 99.123 km from Sabang to Merauke. According to Indonesian Law Number 1 of 2014, it is mentioned that one of the most important biological resources of the coast is mangroves. Some mangrove species commonly found on Lombok Island are Rhizophora mucronata, Sonneratia alba, and Avicennia marina. However, there has not been much exploration of the compound content in these mangroves. Therefore, this study aimed to identify the secondary metabolites of the n-hexane fraction of the three mangrove species using Gas Chromatography-Mass Spectrometry (GC-MS). The leaves of each mangrove species were extracted by sonication method using 96% ethanol solvent, followed by multistage fractionation using n-hexane and water. GC-MS analyzed the n-hexane fraction of each mangrove species. The GC-MS analysis revealed that in the n-hexane fraction of mangrove leaves Rhizophora mucronata and Avicennia marina there were 10 compounds, while Sonneratia alba obtained five compounds. The compounds with the highest intensity in the n-hexane fraction of mangrove leaves of Rhizophora mucronata, Sonneratia alba, and Avicennia marina were squalene (41.71%), ethyl oleate (87.53%), and ethyl oleate (44.02%), respectively. Squalene was reported to have antioxidant and anticancer activities. The ethyl oleate was reported to have bactericidal activity on gram-positive and negative bacteria. The three types of mangrove leaves can be an alternative source of medicine
Uji Efek Ekstrak Collagen Spons Laut (Stylissa flabeliformis) Terhadap Profil Kulit Mencit Sunarwidhi, Anggit Listyacahyani; Deccati, Rizqa Fersiyana; Maulana, Farreh Alan; Utami, Ni Wayan Putri; Dewi, Ni Made Amelia Ratnata
Jurnal Promotif Preventif Vol 7 No 4 (2024): Agustus 2024: JURNAL PROMOTIF PREVENTIF
Publisher : Fakultas Kesehatan Masyarakat Universitas Pancasakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Indonesia merupakan negara dengan biodiversitas tinggi termasuk biota lautnya. Spons laut merupakan sumber alami yang dapat ditemukan dalam jumlah melimpah di perairan Indonesia dan mengandung berbagai komponen bioaktif termasuk collagen yang bermanfaat untuk kesehatan kulit. Pada penelitian ini, dilakukan suatu studi efek ekstrak collagen dari spons laut Stylissa flabelliformis terhadap profil kulit mencit (Mus musculus L.). Spons laut tersebut diambil dari perairan Lombok Utara Indonesia kemudian ekstraksi collagen dilakukan dengan menggunakan Tris-HCl Buffer diikuti dengan pengendapan collagen menggunakan asam asetat. Selanjutnya dilakukan karakterisasi ekstrak collagen dengan menggunakan FTIR-Spectroscopy. Studi efek ekstrak collagen terhadap profil mencit dilakukan selama 14 hari. Hasil penelitian ini menunjukkan bahwa pemberian ekstrak collagen spons laut Stylissa flabelliformis secara topikal ini dapat meningkatkan kadar minyak (sebum) dan kelembapan kulit (moisture), meskipun tidak signifikan. Sedangkan elastisitas kulit dan kandungan collagen kulit tidak terpengaruh. Dapat disimpulkan bahwa penggunaan ekstrak collagen ini dapat memperbaiki profil kelembapan kulit, sehingga dapat dikembangkan sebagai pelembap alami.
Solusi sehat di lahan sempit: edukasi penanaman TOGA mandiri di perkotaan Ananto, Agus Dwi; Muliasari, Handa; Deccati, Rizqa Fersiyana
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 2 (2025): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v6i2.622

Abstract

Tanaman Obat Keluarga (TOGA) are a valuable local resource that can be cultivated as an alternative approach to maintaining family health independently. However, public knowledge and practical skills related to the types of TOGA and proper cultivation techniques remain limited. This community service program aimed to improve community awareness and skills in cultivating TOGA within household environments. The program was implemented through socialization activities using educational pamphlets, instructional videos, and interactive door-to-door discussions across three target areas: urban settlements, rural villages, and residential complexes. The results demonstrated a significant improvement in participants' knowledge of TOGA varieties. Before the program, only about 40% of participants were familiar with more than five types of TOGA, which increased to 85% after the socialization activities. Furthermore, over 75% of participants could correctly describe the basic steps of TOGA cultivation, and approximately 60% of households had already begun planting TOGA in their yards or using simple containers such as pots and polybags. Evaluation also revealed strong enthusiasm and active involvement, as evidenced by participants' engagement in discussions and their initiative to form small groups for continuous TOGA development. In conclusion, this community service activity successfully enhanced participants' knowledge, skills, and motivation to cultivate TOGA. The program is expected to contribute to long-term community self-reliance in herbal-based health maintenance and foster the establishment of sustainable TOGA communities within local neighborhoods.
EDUKASI DAN PELATIHAN PEMBUATAN NUTRASETIKAL WEDANG RONDE PADA MASYARAKAT DESA GEGERUNG LOMBOK BARAT Deccati, Rizqa Fersiyana; Muliasari, Handa; Permatasari, Lina; Saputra, Yoga Dwi
Jurnal Pepadu Vol 4 No 4 (2023): Jurnal Pepadu
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v4i4.3803

Abstract

Nutrasetikal merupakan pangan atau bagian dari pangan yang memberikan manfaat medis atau kesehatan, meliputi pencegahan dan terapi suatu penyakit. Jahe (Zingiber officinale Roscoe) merupakan salah satu tumbuhan perenial yang banyak dijumpai di Indonesia dan dapat diolah menjadi nutrasetikal yang bermanfaat bagi kesehatan seperti wedang ronde. Melalui kegiatan pengabdian kepada masyarakat ini ibu-ibu PKK Desa Gegerung, Kecamatan Lingsar, Lombok Barat, Nusa Tenggara Barat diberikan edukasi dan pelatihan pembuatan nutrasetikal wedang ronde. Tahapan pada kegiatan ini meliputi persiapan kegiatan, pelaksanaan sosialisasi, pelatihan pembuatan nutrasetikal dengan metode partisipatif dan evaluasi kegiatan melalui pemberian umpan balik oleh peserta. Melalui kegiatan ini, pengetahuan terhadap nutrasetikal meningkat dan peserta mendapatkan kemampuan di dalam pembuatan wedang ronde. Berdasarkan hasil kuesioner juga diketahui bahwa 94% peserta merasa kegiatan ini dirasa sangat baik dan sangat bermanfaat. Peserta juga merasa dapat mengaplikasikan ilmu yang didapat setelah pelatihan ini. Nutraceuticals are foods or parts of food that provide medical or health benefits, including prevention and therapy of disease. Ginger (Zingiber officinale Roscoe) is a perennial plant that is often found in Indonesia and can be processed into nutraceuticals that are beneficial for health such as wedang ronde. Through this community service activity, PKK women in Gegerung Village, Lingsar District, West Lombok, West Nusa Tenggara were given education and training in making the nutraceutical wedang ronde. The stages in this activity include activity preparation, implementation of socialization, training in making nutraceuticals using participatory methods and evaluation of activities through providing feedback by participants. Through this activity, participant’s knowledge of nutraceuticals increased and participants gained skills in making wedang ronde. Based on the results of the questionnaire, it was also known that 94% of participants felt that this activity was very good and very useful. Participants also felt they could apply the knowledge gained after this training
Determination of total flavonoid content of extract and fractions of mangrove leaves (Avicennia marina) Annas, Zulfiana Fitrianingrum; Muliasari, Handa; Deccati, Rizqa Fersiyana; Permatasari, Lina; Mukhlishah, Neneng Rachmalia Izzatul
Jurnal Agrotek Ummat Vol 10, No 3 (2023): Jurnal Agrotek Ummat
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jau.v10i3.16596

Abstract

Mangrove plants (Avicennia marina) come from the Avicenniaceae family. The leaves have antioxidant, antiviral and antibacterial activity caused by the content of secondary metabolites in mangrove leaves in the form of flavonoid compounds. Research on the total flavonoid content of 96% ethanol extract and the water, ethyl acetate, and n-hexane fractions of A. marina leaves has never been carried out. The aim of this study was to determine the total flavonoid content in extracts and fractions of A. marina mangrove leaves by UV-Vis spectrophotometry method. Extraction was carried out using 96% ethanol solvent by sonication method, then fractionation was carried out using the liquid-liquid fractionation method. The extracts and fractions obtained for their secondary metabolites were identified by test tube and thin layer chromatography and then the total flavonoid content was determined by the colorimetric method. Mangrove leaf extracts and fractions contain secondary metabolites of flavonoids, phenolics, saponins, steroids, triterpenoids, and alkaloids. The results of thin layer chromatography confirmed the results of the tube test that mangrove leaf extracts and fractions contained flavonoid compounds. Total flavonoid content in 96% ethanol extract, water fraction, ethyl acetate fraction, and n-hexane fraction of A. marina mangrove leaves were 19.37; 3.07; 11.30; and 56.62 mg quercetin equivalent/gram sample. In conclusion, the total flavonoid content of A. marina leaves was high, thus supporting its activity as an antioxidant.
Co-Authors Agus Dwi Ananto, Agus Annas, Zulfiana Fatianingrum Annas, Zulfiana Fitrianingrum Hasina, Raisya Mahacita Andanalusia Maulana, Farreh Alan Maziya, Raehanul Mukhlishah, Neneng Rachmalia Izzatul Muliasari, Handa Muliasari, Handa Ni Made Amelia Ratnata Dewi Nirmala, Annisa Rizka Permatasari, Lina Putri, Enda Desideria Radiartini, Ni Nyoman Rahman, Fania Sammanta, Rahula Vijja Saputra, Yoga Dwi Sunarwidhi, Anggit Listyacahyani Suryadnyani, Ni Made Detia Utami, Ni Wayan Putri Yayuk Andayani