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Risk Factor in Senile Xerosis Mujahid, Sabila Izzatina Azmy
PROMOTOR Vol. 8 No. 2 (2025): APRIL
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v8i2.1142

Abstract

Aging is a progressive process that affects the functionality and maximum capacity of all organs, including the skin. In the elderly population (age >65), skin aging leads to conditions like xerosis senilis, pruritus senilis, and senile comedones, which are commonly observed. Xerosis senilis, or dry skin, results from impaired skin barrier function, increased transepidermal water loss, reduced skin hydration, and decreased lipid components such as ceramides, cholesterol, and free fatty acids in the stratum corneum. These factors make the skin more susceptible to infections, ulcerations, and chronic wounds. This condition manifests as dry, fissured, and rough skin, particularly on the extremities, and can progress to inflammation or infections, impacting quality of life through discomfort, stress, and daily activity interference. Xerosis affects approximately 50% of the elderly, with global prevalence ranging from 29.5% to 85%, correlating with increased age. While the exact risk factors for xerosis senilis remain unclear, genetic, environmental, and comorbid conditions such as hypertension, renal impairment, and diabetes mellitus are implicated. This review examines these risk factors and their mechanisms in contributing to xerosis senilis in the elderly population.
Comprehensive Analysis of Abortion: Risk Factors, and Management in Reproductive Health Musyarof, Disa Fadil; Zahira, Lu’lu Al Fatina; Rifa’i, Ahmad Nur; Iqlima, Aisya Yafis; Aziri, Zirly Vera; Putra, Anak Agung Gede Agung Difa Agusta Pramana; Mujahid, Sabila Izzatina Azmy; Zulkarnaen, Decky Aditya
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7915

Abstract

Abortion is defined as the process of expelling the products of conception before the fetus is fit to survive. The fetus is said to be viable or able to survive when it reaches 20 weeks of pregnancy or weighs 500 grams. The purpose of this article is to provide a comprehensive understanding of abortion, including definition, epidemiology, etiology, risk factors, classification, and management of abortion. The method used is a literature review that includes various academic sources and the latest research related to abortion. Based on the type of occurrence, abortion is divided into two, namely spontaneous abortion and intentional abortion.. Based on the type of event, abortion is divided into two, namely spontaneous abortion and intentional abortion. Intentional abortion is divided into abortion provokatus medicinalis or abortion carried out with medical indications and abortion provokatus criminalis, namely abortion without a valid medical reason. Meanwhile, based on the clinical picture, abortion is divided into several types, namely imminens abortion, incipient abortion, incomplete abortion, complete abortion, missed abortion, and septic abortion. The various types of abortion have their own management.
Gingerol: Anti-inflammatory Compound in Ginger (Zingiber officinale) as Potential Drug Ingredient for Rheumatoid Arthritis Azmi, Naurah Arika; Arsy, Lazuardi; Faqih, Fauzan; Lukman, Dian Azizah; Fariztia, Alifia Intan; Haq, Andi Muhammad Al Fatih; Mujahid, Sabila Izzatina Azmy
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7948

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the joints, with a global prevalence of approximately 0.5-1% of the adult population. Conventional RA treatments often have side effects, prompting the exploration of alternative options. This study aims to explore and review the potential of gingerol, an anti-inflammatory compound found in ginger (Zingiber officinale), as a treatment for RA. The method used was a literature review of 39 relevant articles. The results indicate that gingerol exhibits anti-inflammatory activity by inhibiting pro-inflammatory cytokines and modulating inflammatory pathways. In conclusion, gingerol from ginger shows significant potential as an alternative treatment for RA, although further research is needed to overcome challenges in the extraction process and product development.