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HIPOTIROIDSME : ETIOLOGI, FAKTOR RISIKO DAN TATALAKSANA KOMPREHENSIF Salsabilah, Maida Sania; Iqlima, Aisya Yafis; Harliza, Baiq Fanindya; Lukman, Dian Azizah; Azmi, Naurah Arika; Fariztia, Alifia Intan; Rahman, Moch. Aulia; Islamy, Habiel; Humam, Anang Muh. Nufal; Akbar, Nugraha Malik; Rahmat, Basuki
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.36775

Abstract

Hipotiroidisme adalah keadaan dimana kelenjar tiroid tidak mampu memproduksi hormon tiroid yang dibutuhkan oleh tubuh. Gejala hipotiroidisme dapat ringan dan sering kali tidak disadari oleh penderitanya. Gejala paling umum dari hipotiroidisme adalah kelelahan, kelesuan, intoleransi dingin dan kenaikan berat badan.  Metode yang digunakan dalam penulisan tinjauan pustaka ini adalah studi literatur dari berbagai referensi. Pencarian literatur ini menggunakan basis data online yaitu, PubMed, Google Scholar, ProQuest dan Mendeley Search. Hipotiroidisme merupakan salah satu penyakit paling umum di seluruh dunia. Diperkirakan sekitar 5% dari populasi yang mengalami hipotiroidisme prevalensi lebih tinggi pada wanita dibandingkan dengan laki-laki dan prevalensi lebih rendah ditemukan pada populasi berusia dibawah 22 tahun. Hipotiroidisme dapat dikalsifikasikan menjadi 3 yaitu, hipotiroidisme primer, hipotiroidisme sentral dan hipotiroidisme perifer. Penyebab paling umum dari hipotiroidme adalah kekurangan yodium. Pemeriksaan yang dapat dilakukan untuk hipotiroidisme adalah dengan menghitung skor berdasarkan skala Billewicz dan Zulewski dan diperlukan juga pemeriksaan laboratorium seperti pemeriksaan TPO Ab untuk kecurigaan tiroiditis autoimun. Terapi yang digunakan dalam tatalaksana hipotiroidisme adalah livotiroksin yang menjadi standar baku emas, selain terapi farmokologi terdapat terapi non farmakologi seperti membatasi konsumsi gula, konsumsi zinc, konsumsi selenium, konsumsi vitamin B12, diet bebas gluten dan tidur yang cukup. Hipotiroidisme berat yang tidak diobati dan berlangsung lama akan menimbulkan komplikasi berupa miksedema.
Skin Manifestation of Crohn's Disease Rahman, Moch. Aulia; Islamy, Muhammad Habiel; Harliza, Baiq Fanindya; Iqlima, Aisya Yafis; Lukman, Dian Azizah; Azmi, Naurah Arika; Fariztia, Alifia Intan; Humam, Anang Muh. Naufal; Salsabila, Maida Sania; Akbar, Nugraha Malik; Alaydrus, M. Mukaddam
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7790

Abstract

Skin Manifestation of Internal Disease is a condition that refers to changes or abnormalities in the skin that are related to or caused by systemic diseases or disorders of other internal organs of the body. Sweet's Syndrome as one of the skin manifestations that can occur in patients with Crohn's Disease. The purpose of this article is to determine the definition, etiology, epidemiology, pathophysiology, clinical manifestations, epidemiology and management of skin manifestations of Crohn's disease. The method used is a literature review of articles related to Skin Manifestation of Crohn's disease, which processes information and data from various related articles to obtain conclusions. Articles used related to this study were obtained through searches in databases such as PubMed, Google Scholar, and Sciencedirect. The publication year limit used in this article is at least 10 years. Sweet's Syndrome or known as Acute Febrile Neutrophilic Dermatosis (AFND) is a prototype of neutrophilic dermatosis disease characterized by acute onset neutrophilic dermal lesions, leukocytosis, and pyrexia. Based on its etiology, sweet syndrome is grouped into 3 subtypes: Classic Sweet's Syndrome (Idiopathic Sweet's Syndrome), Drug Induced Sweet's Syndrome, Malignancy-Associated Sweet's Syndrome. Therefore, it is important for clinicians to recognize Sweet's syndrome as one of the skin manifestations in CD patients so that appropriate treatment can be given.
Aspiration Pneumonia: Patophysiology, Diagnosis and Treatment Kirana, Devi Chandra; Fathana, Prima Belia; Ristia, Ovia Intan; Mario, Andina Nabilah; Lukman, Dian Azizah; Abdiman, I Made Tobias; Putra, Made Raditya Arhya; Salsabila, Maida Sania
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7897

Abstract

Aspiration pneumonia is one of the diseases that is often hidden and under-recognized. This disease contributes to a higher mortality rate compared to other types of pneumonia. This study aims to analyze the pathophysiology, diagnosis and management of aspiration pneumonia. The method used is a literature study by searching for literature published in PubMed, ScienceDirect, and Researchgate with the keywords "aspiration pneumonia", "aspiration pneumonia pathophysiology", "aspiration pneumonia diagnosis and treatment". Aspiration pneumonia can occur due to micro mechanisms or macro mechanisms. Micro mechanisms are mechanisms that cannot be observed while macro mechanisms often occur due to impaired swallowing. Aspiration experienced by pneumonia patients causes inflammation and disruption of the epithelium. The diagnosis of aspiration pneumonia can be established based on clinical symptoms and supporting examinations such as radiology and laboratory examinations. Management that can be carried out on aspiration pneumonia can be done with pharmacological and non-pharmacological management.
Gingerol: Anti-inflammatory Compound in Ginger (Zingiber officinale) as Potential Drug Ingredient for Rheumatoid Arthritis Azmi, Naurah Arika; Arsy, Lazuardi; Faqih, Fauzan; Lukman, Dian Azizah; Fariztia, Alifia Intan; Haq, Andi Muhammad Al Fatih; Mujahid, Sabila Izzatina Azmy
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7948

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the joints, with a global prevalence of approximately 0.5-1% of the adult population. Conventional RA treatments often have side effects, prompting the exploration of alternative options. This study aims to explore and review the potential of gingerol, an anti-inflammatory compound found in ginger (Zingiber officinale), as a treatment for RA. The method used was a literature review of 39 relevant articles. The results indicate that gingerol exhibits anti-inflammatory activity by inhibiting pro-inflammatory cytokines and modulating inflammatory pathways. In conclusion, gingerol from ginger shows significant potential as an alternative treatment for RA, although further research is needed to overcome challenges in the extraction process and product development.