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All Journal Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Pena Medika : Jurnal Kesehatan Journal of Pharmaceutical and Health Research Jurnal Buana Farma Journal of Social Responsibility Projects by Higher Education Forum Kolaborasi Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Pharmacy Genius Journal of Pharmaceutical and Sciences.
Kurniasih, Khamdiyah Indah
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Efektivitas Leaflet dalam Meningkatkan Pengetahuan Hipertensi pada Lansia di Desa Gandatapa Kusuma, Ikhwan Yuda; Nawangsari, Desi; Prabandari, Rani; Kurniasih, Khamdiyah Indah; Fauziah, Fauziah; Abely, Nastasya Anis; Safitri, Cindy Ade
Kolaborasi: Jurnal Pengabdian Masyarakat Vol 4 No 5 (2024): Kolaborasi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/kolaborasi.v4i5.437

Abstract

Introduction:  Hypertension is a significant global health issue that often presents without symptoms, leaving many individuals unaware of their condition. Effective management and prevention of hypertension require increased awareness and education, particularly among the elderly population, who are at higher risk. Objective: This study aims to evaluate the effectiveness of health counseling using leaflets in improving hypertension knowledge among the elderly at Integrated service post (Posyandu) community association (RW) 4 Gandatapa. Method: This descriptive quantitative study employed a pre-post design. Health counseling was conducted using leaflets at  Integrated service post  (Posyandu) community association (RW) 4 Gandatapa on July 16, 2024, involving 44 elderly participants aged 65-70 years. Knowledge levels were assessed using pre-test and post-test questionnaires. The intervention included distributing leaflets and conducting a discussion session to reinforce the information provided. Result:The study observed a significant increase in participants' knowledge about hypertension, with average knowledge scores rising from 43% in the pre-test to 63% in the post-test. Conclusion: The findings suggest that health counseling using leaflets is an effective method for improving hypertension knowledge among the elderly. However, to optimize the impact, future interventions should consider additional support methods, especially for those with limited literacy or visual impairments.
Analisis Pengaruh Vaksin Covid-19 Terhadap Nilai HbA1c Pasien DM Tipe-2 Di Puskesmas: Studi Retrospektive Setyaningsih, Intan Wiji; Kurniasih, Khamdiyah Indah; Setianingsih, Siti
Journal of Pharmaceutical and Health Research Vol 5 No 3 (2024): October 2024
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v5i3.5666

Abstract

Coronavirus Disease 2019 (Covid-19) is a dangerous type of infection that causes death and is at risk in DM patients, so the selection of vaccines is very selective, especially moderna or pfizer vaccines that will know the increase in blood glucose. The purpose of this study was to determine the description and relationship of HbA1c values in type 2 DM patients after the 2nd dose of moderna or pfizer Covid-19 vaccine at Mrebet Health Center. The method used was analytical research with a retrospective observational approach conducted by conducting interviews with DM patients in the form of compliance with drug use, remaining drug use in 1 month, and sugar diet. Measurement of HbA1c values obtained from 3 months before and 3 months after the 2nd dose of moderna or pfizer vaccine. The results of the study obtained 32 DM prolanis patients, where the most patients were aged 45 - 65 years as many as 28 (87.5%), and female gender 27 (84.4%). The type of vaccine obtained was 25 (78.1%) moderna vaccine and 7 (21.9%) pfizer vaccine. The average pre-vaccine and post-vaccine HbA1c values increased by 0.3% from 8.0% to 8.3% and a standard deviation of 0.10. Based on the analysis, the p-value of 0.000 <0.050 was obtained, so statistically there was a slight increase with almost the same value between HbA1c values in type 2 DM patients after the Covid-19 moderna vaccine or the 2nd dose of pfizer. Conclusion There is an increase between pre-vaccine and post-vaccine HbA1c values and there is a relationship between HbA1c values in patients with type 2 DM after the Covid-19 moderna or pfizer 2nd dose vaccine.
EVALUASI PENGGUNAAN OBAT PADA PASIEN DISPEPSIA DI RUMAH SAKIT SWASTA DI PURWOKERTO Ardhana, I Putu Primanda Dodi; Kurniasih, Khamdiyah Indah; Fauziah
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 9 No 2 (2024): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v9i2.8149

Abstract

Dyspepsia is a gastrointestinal disorder that affects the stomach. In the event that the pharmaceutical agents employed for the treatment of dyspepsia are not selected in a rational manner, there is a potential for therapeutic failure, the emergence of more serious health complications, the manifestation of adverse drug reactions, and the unnecessary utilization of pharmaceuticals. The objective of this study was to assess the rationality of drug use for dyspepsia patients at a hospital in Purwokerto, specifically focusing on the appropriateness of the selected drug, dosage, and indication. This research is descriptive and employs a retrospective approach. A total sampling technique was employed, yielding a total sample of 71 medical records from the period between January and February 2024. The data collection was conducted in April 2024. The instruments utilized in this study were observation sheets and medical records. The results of this study indicate that the use of drugs for dyspepsia patients at a private hospital in Purwokerto is, in fact, rational. Specifically, the drugs used were deemed to be the appropriate medication 98.6% of the time, the dosage was deemed to be appropriate 100% of the time, and the indication for use was deemed to be appropriate 100% of the time. Therefore, it can be concluded that the use of drugs in dyspepsia patients in private hospitals in Purwokerto is, in fact, rational.
Pelatihan Pembuatan Lilin Aromaterapi Antinyamuk Pada Anggota Fatayat Nu Ranting Purwosari Nawangsari, Desy; Kurniasih, Khamdiyah Indah; Prabandari, Rani; Fitri, Ely Nurul
Kolaborasi: Jurnal Pengabdian Masyarakat Vol 5 No 2 (2025): Kolaborasi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/kolaborasi.v5i2.484

Abstract

Introduction: Used cooking oil is oil that has been used repeatedly up to 3-4 times frying. The negative impact of used cooking oil if thrown away will become waste and damage the surrounding environment. One of the products of used cooking oil processing is aromatherapy candles and soap. Various forms of aromatherapy have sprung up such as essential oils, candles, incense, soaps and massage oils. People only use candles as a source of lighting when there is no electricity source. The function of candles is not only a lighting aid but is widely used as a room decorator and as a room fragrance, in this case what is commonly used is aromatherapy candles. Objective: The objectives of this activity are (1) Minimizing the disposal of used cooking oil (2) Changing the lifestyle of the community to process used cooking oil waste based on zero waste industry (3) Reducing the disposal of used cooking oil in any place can reduce the risk of groundwater pollution (4) Creating anti-mosquito aromatherapy candle products that have economic value. Method: The method of implementing the activity was carried out by providing material on the utilization of used cooking oil and training in making aromatherapy candle products for mosquitoes. Result: The outputs of this activity are increased knowledge related to products and the risk of contamination to the environment, increased knowledge and skills of partners in making aromatherapy candles. Conclusion: The training on making mosquito-repellent aromatherapy candles from used cooking oil successfully improved participants' knowledge and skills. It supports waste reduction and economic empowerment. Despite challenges in raw material consistency, the program holds potential for sustainability and commercialization.
Analisa Fitokimia dan Aktivitas Antioksidan Sirup Herbal Ekstrak Buah Labu (Curcubita Moschata) dan Rimpang Kunyit (Curcuma Domestica) dengan Metode DPPH Kurniasih, Khamdiyah Indah; Fauziah, Fauziah; Misworo, Misworo; Prismadito, Hansen
Journal of Pharmaceutical and Health Research Vol 6 No 1 (2025): February 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i1.6189

Abstract

Pumpkin is one of the natural ingredients with antioxidant properties, and it helps reduce symptoms of diabetes, hypertension, tumors, cholesterol, antibacterial, anthelmintic, and anti-inflammatory effects. The polyphenol and flavonoid contents in pumpkin are 97.4 mgGAE/gram and 28.6 mgQE/gram, respectively, with high antioxidant activity against DPPH radicals at 0.065 ± 0.010 mol TE/gram. Turmeric rhizome is also a plant with high antioxidant activity. Turmeric rhizome contains curcumin as the main active compound, with a content of 7.798%. The ethanol extract of turmeric rhizome exhibits antioxidant activity with an IC50 value of 41.95 µg/mL (DPPH). Studies on the composition and benefits of pumpkin and turmeric rhizome have been conducted. However, so far, there has been no standardization of the simplicia and extracts of these two plants from Central Java. The herbal syrup combining pumpkin and turmeric extracts is an herbal product that has not been scientifically proven regarding its metabolite compounds and antioxidant activity, which play a role in addressing various degenerative diseases. Therefore, standardization of the simplicia and verification of the phytochemical metabolites and antioxidant content are necessary. This study was conducted by comparing the IC50 values of three syrup formulas: turmeric rhizome syrup (F1), pumpkin syrup (F2), and a mixture of pumpkin and turmeric rhizome syrup (F3). The results showed that Formula 1 (F1) had the lowest IC50 value of 17.366 µg/mL, indicating the highest antioxidant potential, followed by F3 with an IC50 of 47.862 µg/mL, and F2 with the lowest antioxidant activity, with an IC50 value of 288.545 µg/mL.
Tingkat Penggunaan Antibiotik dan Pola Peresepannya Pada Infeksi Saluran Pernapasan (ICD-10: J00-J99) di Indonesia Selama Pandemi COVID-19 Misworo, Misworo; Kusuma, Ikhwan Yuda; Kurniasih, Khamdiyah Indah; Nurkholis, Fiqih; Fauziah , Fauziah
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.849

Abstract

Introduction: Respiratory tract infections (RTIs) contribute substantially to global antibiotic consumption, raising concerns about antimicrobial resistance (AMR). This study aimed to analyze antibiotic prescribing patterns for respiratory disorders in an Indonesian teaching hospital during the COVID-19 pandemic. Methods: This retrospective, cross-sectional study examined systemic antibiotic prescriptions based on the Anatomical Therapeutic Classification (ATC: J01) for respiratory diseases (ICD-10: J00-J99) at Cilacap Government Teaching Hospital between January and December 2021. Data were extracted from electronic medical records (e-MR), including patient demographics (i.e. age and sex), ICD codes and name of antibiotics. We analyzed WHO AWaRe classifications, administration routes, and seasonal patterns based on patient’s entry and antibiotic use. Results: The study included 2,395 patients with antibiotic prescriptions for respiratory disorders. The Watch group antibiotics accounted for 85.6% of prescriptions, with the highest use among adults (86.2%). Parenteral administration (71.5%) was more common than oral administration (28.5%). Pneumonia (38.2%) and chronic obstructive pulmonary disease (27%) were the most common indications. Antibiotic use peaked in December (n=529) and was lowest in July (n=84). Ceftriaxone (n=838), azithromycin (n=270), cefixime (n=262), levofloxacin (n=216), and meropenem (n=56) were among the top prescribed antibiotics. Conclusion: The study highlights the predominant use of broad-spectrum and parenteral antibiotics for respiratory disorders, raising concerns about AMR. Factors such as seasonality, disease patterns, and diagnostic challenges may have influenced prescribing practices. Implementing antimicrobial stewardship programs, promoting evidence-based guidelines, and addressing modifiable risk factors are crucial to combat AMR and optimize patient outcomes during and beyond the COVID-19 pandemic.
Pelatihan Pemanfaatan Limbah Minyak Jelantah Menjadi Lilin Aromaterapi Di Desa Windujaya Kurniasih, Khamdiyah Indah; Samodra, Galih; Setianingsih, Siti; Nurkholis, Fiqih; Hakim, Lukman
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 4, No 1 (2025)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v4i1.31247

Abstract

Minyak jelantah adalah minyak yang telah digunakan secara berulang-ulang hingga 3-4 kali penggorengan. Dampak negative dari minyak goreng bekas jika dibuang begitu sajatanpapengolahanakanmenjadilimbahdanakanmerusaklingkungansekitar.Salahsatubentuk  produk hasil pengolahan minyak goreng bekas adalah lilin aromaterapi. Sasaranmitra  pengabdian ini adalah masyarakat ekonomi non produktif di desaWindujaya yang bekerja bekerja sebagai Ibu Rumah Tangga dan tidak memiliki penghasilan. UrgensiPemberdayaan Masyarakat Pemula ini meningkatkan keterampilan Kelompok Kader DesaWindujaya dalam Pelatihan Pembuatan lilin aromaterapi yang berbahan dasar limbah minyak jelantah. Tujuan kegiatan ini yaitu, meminimalisasipembuangan minyak jelantah, berubahnya pola hidup masyarakat untuk mengolah limbahminyak jelantah berbasis zero waste industry, berkurangnya pembuangan minyak jelantahdisembarang tempat dapat mengurangi resiko pencemaran air tanah, dan erciptanya produklilinaromaterapidansabunbernilaiekonomis. Kegiatan ini telah terlaksana pada tanggal 18 agustus 2024 dengan peserta ibu rumah tangga yang ada di Desa Winduajaya, Banyumas. Metode Kegiatan ini menggunakan metode difusi ilmu pengetahuan dan teknologi (ipteks) dengan tahapan berupa tahapan persiapan dan koordinasi terkait dengan pengetahuan Masyarakat terhadap lombah minyak jelantah ,Pemberdayaan Masyarakat, monitoring dan evaluasi serta sasaran pelatihan.  Hasil pengabdian didapat bahwa terdapat peningkatan pengetahuan terkait pemanfaatan limbah minyak jelantah dalam bentuk lilin aromaterapi.
Pelatihan Pembuatan Serbuk Poliherbal Kombinasi Rimpang Jahe, Kunyit Dan Serai Di Desa Windujaya Fauziah, Fauziah; Rahmawati, Nur; Kurniasih, Khamdiyah Indah
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 4, No 2 (2025)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/phar.soc.v4i2.31264

Abstract

Masyarakat Desa Windujaya masih banyak yang belum mengetahui tentang manfaat poliherbal dan minimnya pengetahuan tentang pengolahan tanaman obat tradisional. Tanaman seperti jahe, kunyit, temulawak, dan serai telah lama dikenal memiliki berbagai manfaat kesehatan, seperti meningkatkan daya tahan tubuh, melancarkan pencernaan, dan meredakan peradangan. Pelatihan pembuatan minuman herbal fungsional yang dilaksanakan di Desa Windujaya,  bertujuan untuk memberdayakan masyarakat, khususnya ibu-ibu PKK, dengan meningkatkan kreativitas mereka dalam mengolah tanaman herbal lokal menjadi produk bernilai jual. Pelatihan ini juga bertujuan untuk membuka peluang usaha baru yang dapat mendukung ekonomi keluarga dan memperkenalkan produk kesehatan alami kepada masyarakat luas. Metode yang diterapkan dalam pelatihan ini mencakup dua komponen utama, yaitu edukasi dan praktik langsung. Pada tahap edukasi, peserta diberi pengetahuan tentang manfaat berbagai tanaman herbal yang digunakan dalam pembuatan minuman, serta cara pengolahannya yang tepat untuk menjaga kandungan nutrisinya. Tahap praktik melibatkan pengolahan tanaman herbal menjadi minuman instan yang dapat diseduh untuk menghasilkan minuman fungsional yang tidak hanya sehat, tetapi juga mudah diproduksi dan dikonsumsi. Hasil dari pelatihan ini menunjukkan peningkatan yang signifikan dalam keterampilan peserta, yang dapat dilihat dari antusiasme tinggi ibu-ibu PKK dalam mengikuti seluruh rangkaian pelatihan. Mereka juga menunjukkan pemahaman yang lebih baik mengenai manfaat kesehatan dari setiap tanaman yang digunakan. Program ini menghasilkan produk poliherbal dari kombinasi rimpang jahe, kunyit, dan serai yang diformulasikan untuk manfaat kesehatan alami. Program ini juga memberi kesempatan bagi masyarakat desa untuk mengenal lebih dalam mengenai produk kesehatan alami, yang dapat menjadi alternatif yang lebih sehat dibandingkan dengan produk-produk olahan lainnya yang banyak beredar di pasaran. Walaupun pelatihan ini sudah memberikan keterampilan dasar dalam pembuatan produk, pengetahuan tentang cara memasarkan produk, memperkenalkan produk ke pasar yang lebih luas, serta mengelola usaha kecil sangat penting untuk memastikan keberhasilan jangka panjang. Oleh karena itu, pelatihan lanjutan mengenai strategi pemasaran dan manajemen usaha sangat dibutuhkan untuk meningkatkan potensi usaha ini dan mencapai hasil yang maksimal.
Evaluasi Fisik Facial Wash Ekstrak Daun Sirsak (Annona Muricata L.) Berbasis Gelling Agent Ulinnuha, Alvin; Fauziah, Fauziah; Kurniasih, Khamdiyah Indah; Nawangsari, Desy; Prabandari, Rani
Pharmacogenius Journal Vol 3 No 3 (2024): Pharmacy Genius
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/pharmgen.v3i03.396

Abstract

Pendahuluan: Perbedaan jenis Gelling Agent dapat memengaruhi sifat fisik dari sediaan dikarenakan perbedaan sifat fisika kimianya. Konsentrasi Gelling Agent yang tidak sesuai standar seperti pemakaian dengan konsentrasi tinggi atau bobot molekul besar dapat menghasilkan sediaan gel yang sulit dikeluarkan pada kemasan. Tujuan: Tujuan penelitian ini adalah untuk mengetahui sifat fisik, iritasi primer, dan hedonik sediaan gel Facial Wash ekstrak daun sirsak dengan variasi Gelling Agent Na-CMC, HPMC, Carbopol 940. Metode: Metode pada penelitian ini menggunakan metode eksperimental laboratorium dengan 3 formula dimana formula 1 menggunakan basis Na-CMC, formula 2 menggunakan basis HPMC, dan formula 3 menggunakaan basis Carbopol 940. Hasil: Hasil uji sifat fisik sediaan menunjukkan semua formula memenuhi rentang persyaratan sifat fisik gel yang baik. Hasil uji iritasi diketahui bahwa semua formula tidak menimbulkan edema dan eritema pada hewan uji dan mendapatkan skor indeks iritasi primer sebesar 0,0. Hasil uji hedonik didapatkan hasil formula 3 menempati ranking pertama paling disukai kemudian formula 1 pada ranking 2 dan formula 2 pada ranking terakhir. Hasil pengujian statistik sifat fisik semua parameter menunjukan signifikansi < 0,05 yang artinya terdapat perbedaan signifikan antara F1, F2, F3 kecuali parameter tinggi busa dan persen daya busa menunjukan tidak ada perbedaan sinifikan antara F1, F2, F3 dengan signifikansi > 0,05. Kesimpulan: Kesimpulan pada penelitian ini adalah semua formula memiliki sifat fisik yang baik, tidak menimbulkan iritasi dan memiliki hasil kesukaan yang berbeda beda.
FORMULASI SEDIAAN ORALLY DISINTEGRATING TABLET (ODT) ASPIRIN DENGAN SODIUM STARCH GLYCOLATE SEBAGAI SUPERDISINTEGRANT Putri, Arine Astika; Nawangsari, Desy; Kurniasih, Khamdiyah Indah
Pena Medika : Jurnal Kesehatan Vol. 14 No. 1 (2024): PENA MEDIKA: JURNAL KESEHATAN
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/pmjk.v14i1.3713

Abstract

Aspirin adalah NSAID salisilat yang digunakan sebagaiagen antiplatelet dalam pengobatan stroke. Kematianakibat stroke dalam waktu 5 tahun, lebih dari separuhpasien stroke berusia dangt; Seorang berusia 45 tahunyang meninggal. Banyak pasien lanjut usia yang tidak maumenerima/mengonsumsi tablet karena takut tersedak ataukesulitan menelan. Tablet yang hancur secara oral (ODT) adalah sediaan yang lebih cepat hancur, hancur dalamwaktu kurang dari 60 detik bila dimasukkan ke dalammulut, dan tidak memerlukan tambahan air untuk ditelan. Tujuan penelitian ini adalah untuk mengetahui pengaruhkonsentrasi bahan penghancur sodium starch glycolateterhadap sifat fisik dan kelarutan formulasi aspirin orally disintegrating tablet (ODT) serta mengetahui konsentrasibahan penghancur sodium starch glycolate. zat dalamformulasi aspirin orally disintegrating tablet (ODT) yang sesuai dengan sifat fisik. Tablet Aspirin ODT diproduksidalam empat formulasi dengan konsentrasi sodium starch glycolate 0%, 10%, 15% dan 20%. Evaluasi tablet ODT meliputi keseragaman bobot, keseragaman ukuran, kekerasan, kerapuhan, waktu larut tablet dan uji stabilitas. Data yang dihasilkan kemudian dianalisis menggunakanANOVA satu arah. Hasil penelitian menunjukkan bahwasifat fisik tablet F1, F2, F3 dan F4 meliputi uji keseragaman massa tablet yang menunjukkan hasilANOVA sebesar 0,000 kurang dari 0,05 yaitu selisih uji keseragaman ukuran diameter. . hasilnya 0,056 lebih dari0,05 jadi tidak ada bedanya dan hasilnya kental Selisih0,086 lebih dari 0,05 hasil uji kekerasan 0,000 kurang dari0,05 jadi ada beda hasil uji kerapuhan 0,125 lebih dari0,05 maka terdapat perbedaan, dan hasil uji waktu larut0,03 kurang dari 0,05 maka terdapat perbedaan. Uji disolusi menghasilkan F1 10,1%, F2 10,06%, F3 9,12% dan F4 9,3%. Pada uji kestabilan kimia uji disolusi, hasilpersentase disolusi mengalami perubahan kestabilan harike 14, F1 9,3%, F2 5,8%, F3 12,6% dan F4 12,6%, kestabilan 28 hari F1 10,6%, F2 8,88%, F3 8,9% . dan 8,9%. Mengenai kestabilan fisik, pengujian keseragamanberat tablet, keseragaman ukuran, kekerasan tablet, kerapuhan tablet dan waktu larut stabil tablet diperolehkarena uji stabilitas 0, 14 dan 28 memberikan hasil yang sama. Kata kunci: aspirin, sodium starch glycolate, orally disintegrating tablet
Co-Authors Abely, Nastasya Anis Ardhana, I Putu Primanda Dodi Fauziah Fauziah , Fauziah Fauziah Fauziah Fitri, Ely Nurul Ikhwan Yuda Kusuma Kirana, Ade Lukman Hakim Melani, Reina Misworo, Misworo nawangsari, desi Nawangsari, Desy Nur Rahmawati Nurkholis, Fiqih Prabandari, Rani Prismadito, Hansen Putri, Arine Astika Ratna, Uki Septi Safitri, Cindy Ade Samodra, Galih Setyaningsih, Intan Wiji Siti Setianingsih Ulinnuha, Alvin