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Mitigating Anxiety Symptoms: Potential of Phenol Compounds in Organic Red Ginger from Simalungun Regency Dania, Ira Aini; Novziransyah, Nanda; Pangestuti, Dewi; Akbar, Surya; Sari Ayu, Mayang; Lubis, Adi Raja Brando; Ayu, Mayang Sari; Saputra, Donalry Agus
Indonesian Food Science and Technology Journal Vol. 8 No. 2 (2025): Volume 8 Number 2, July 2025 |IFSTJ|
Publisher : Department of Technology of Agricultural product (THP) Jambi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/ifstj.v8i2.34374

Abstract

Abstract— According to WHO (World Health Organization), anxiety disorders affected 266 million people globally in 2019, or 5.3% of the population. As the second most common mental disorder after depression, anxiety impacts 284 million people and significantly contributes to the disease burden worldwide. Meanwhile, regional prevalence rates are 19.2%, 16.2%, 9.0%, and 11.8% in North America, Europe, Africa, and Southeast Asia, with particularly 57.5% and 68.8% rates among pregnant women in Bali (2020) and Semarang (2023), respectively. In this context, ginger (Zingiber officinale), traditionally used for various ailments, contains phenol such as shogaol, zingerone, gingerol, and 6-shogaol, which have antioxidant and anti-inflammatory properties for reducing anxiety. Therefore, this research aims to analyze the phenol contents of ginger using UV-Vis spectrophotometry in the Faculty of Pharmacy, University of North Sumatra. The results show that there is a strong correlation of 0.9794 between gallic acid and phenol content. Additionally, phenol levels are reported with different extraction methods including 43.2653 mgGAE/g (4.326%) with water, 62.7680 mgGAE/g (6.27%) with 70% ethanol, and 129.7456 mgGAE/g (12.97%) with 96% ethanol. The highest phenol content in organic red ginger using 96% ethanol suggests the potential to reduce anxiety by counteracting free radicals.
ADDRESSING HYPERTENSION IS CRUCIAL TO MITIGATING COGNITIVE DECLINE AND IMPROVING PATIENTS' QUALITY OF LIFE Pangestuti, Dewi; Lubis, Adhayani; Lubis, Adi Raja Brando; Mukminin, Amirul; Dania, Ira Aini; Saputra, Donalry Agus; Sajow, Stenly Hely
Jurnal Ilmiah Ilmu Terapan Universitas Jambi Vol. 9 No. 1 (2025): Volume 9, Nomor 1, March 2025
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jiituj.v9i1.34442

Abstract

Hypertension, a condition characterized by persistent elevated blood pressure, often places individuals at risk of developing complications that can adversely impact their quality of life. One notable complication associated with hypertension is cognitive dysfunction. A study published in the Journal of Alzheimer's Disease (2020) demonstrated that individuals with long-standing hypertension exhibited an elevated risk of developing cognitive impairment and Alzheimer's disease. Preliminary research suggests that approximately 12.5 percent of hypertensive deaths may be attributable to underlying factors. Aims: This study aims to examine the cognitive deficits in patients with hypertension and summarise research on the relationship between hypertension and cognitive impairment. This analytical research study with a cross-sectional design, total sample of 84 individuals who suffer from hypertension, the ages of 60 and 79 years old. The sample selected using purposive sampling, instruments used in this study were medical record and Mini Mental State Examination (MMSE) questionnaire. The data was analyzed univariate and bivariate with the Chi Square statistical test. The MMSE cognitive function test revealed that out of 84 individuals with hypertension, 67.85% had normal cognitive function, while 32.14%) moderate cognitive impairment. The sample for the research consisted of 40 male individuals (47.61%) and 44 female individuals (52.38%). Hypertension can affect a person's cognitive function which has an impact on quality of life.