Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal Medula Universa Medicina Jurnal Aisyah : Jurnal Ilmu Kesehatan
Herliyana, Lina
Unknown Affiliation
Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Analysis of Respondent Characteristics Regarding The Severity of Community-acquired Pneumonia Patients at Dr. H. Abdul Moeloek Hospital, Lampung. Sanjaya, Rizki Putra; Herdato, M. Junus Didiek; Ajipurnomo, Adhari; Herliyana, Lina; Dilangga, Pad; Soeprihatini, Retno Ariza; Lyanda, Apri; Hendarto, Gatot Sudiro; Sinaga, Fransisca Tarida Yuniar; Kusumajati, Pusparini
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 10, No 1 (2025): March
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v10i1.3096

Abstract

Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide, particularly among the elderly and immunocompromised patients. Various factors, including age, gender, bacterial pattern, comorbidities, and Pneumonia Severity Index (PSI) score, influence CAP severity. Understanding these characteristics is crucial for optimizing treatment strategies and predicting clinical outcomes. This descriptive-analytical cross-sectional study was conducted at Dr. H. Abdul Moeloek Hospital, Lampung, from December 2022 to January 2023. A total of 102 CAP patients were analyzed based on their age, gender, bacterial pattern, comorbidities, and PSI score. Data were processed using IBM SPSS 21.0, with Pearson correlation applied to assess relationships between variables. A statistically significant correlation was found between age and PSI score (p = 0.018), with a low-strength positive correlation (R = 0.234). This suggests that as age increases, CAP severity also increases (p = 0.011). However, no significant correlations were found between PSI score and gender, bacterial pattern, or diabetes mellitus. This study confirms that age is a significant factor influencing CAP severity, emphasizing the need for early screening and intervention in elderly patients. Although gender, bacterial pattern, and diabetes mellitus were not significantly correlated with CAP severity. 
Profile of multidrug-resistant bacteria causing urinary tract infections in inpatients and outpatients in Jakarta and Tangerang Rosana, Yeva; Herliyana, Lina; Krisandi, Grady; Anggraini Suwarsono, Erike
Universa Medicina Vol. 42 No. 3 (2023)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2023.v42.303-313

Abstract

Background Urinary tract infections (UTIs) caused by bacteria occupy the second highest rank of common infectious diseases in the world. Empirical use of antibiotics may give rise to multidrug-resistant (MDR) bacteria because of irrational prescription. Choice of antibiotics to treat UTIs is limited because of MDR bacteria. Thus, this study was conducted to investigate the bacterial antibiotic susceptibility patterns in inpatients and outpatients in Jakarta and Tangerang. Methods Bacterial isolates were obtained from midstream urine specimens from 43 inpatients and 43 outpatients with UTIs in Jakarta and Tangerang. Bacteria were isolated on blood and MacConkey agar media using colony count method. Isolate identification and their susceptibility patterns were performed using VITEK2 compact system according to manufacturers’ instructions. Data were analyzed using Chi-square test. Results A total of 89 bacterial isolates consisting of 15 bacterial species were successfully isolated from 86 specimens. Gram-negative bacteria were the most common etiology of UTIs in inpatients and outpatients. MDR bacteria were found in 52 of the 89 isolates. ESBL-producing E. coli was the most common MDR bacteria. ESBL-producing E. coli and other MDR bacteria showed good susceptibility to ertapenem, meropenem, amikacin, and tigecycline. There were no significant differences regarding the MDR bacterial count in inpatients and outpatients (p=0.521). Conclusion E. coli was found to be the most common MDR bacteria causing UTIs in inpatients and outpatients in Jakarta and Tangerang. Higher resistance to many antibiotics was found in MDR bacterial isolates in inpatients compared to outpatients. MDR bacteria in outpatient UTIs were highly resistant to commonly used antibiotics.
Anak dengan Tuberkulosis (TB) Paru Kasus Baru Terkonfirmasi Bakteriologis dengan Riwayat Human Immunodeficiency Virus (HIV) yang Menjalani Pengobatan Antiretroviral (ARV) Soemarwoto, Retno Ariza S; Afryan, I Made; Nareswari, Shinta; Sinaga, Fransisca; Saputra, Oktadoni; Herliyana, Lina; Hidayat, Hidayat
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1423

Abstract

Tuberculosis (TB) in children with Human Immunodeficiency Virus (HIV) is a complex clinical challenge due to the synergistic interaction between these two diseases, which mutually worsen the patient's clinical condition. HIV decreases immunity, thus increasing the risk of TB infection, while TB accelerates HIV progressivity. TB-HIV co-infection is a major cause of morbidity and mortality, especially in children with undetected M. Tuberculosis infection. By 2022, an estimated 710,000 HIV patients will develop TB, of which 187,000 will die. This article aims to provide an update on the management of pulmonary TB in children with HIV who are routinely on antiretroviral (ARV) treatment. The discussion covers the definition, epidemiology, etiology, disease progression, pathogenesis, diagnosis, supporting investigations, and management of TB-HIV. The diagnosis of TB in children with HIV is often difficult due to non-specific clinical manifestations and limitations of diagnostic tests. Therefore, early detection through comprehensive testing is essential. TB-HIV management requires a multidisciplinary approach, including appropriate TB treatment and integrated ARV administration. Intensive monitoring is also required to prevent complications, such as drug resistance or adverse effects of therapy. In conclusion, this article emphasizes the importance of a holistic approach in evaluating and managing pulmonary TB in children with HIV, including interprofessional collaboration, family education, and preventive efforts to improve patients' quality of life and reduce mortality.
Co-Authors Afryan, I Made Ajipurnomo, Adhari Anggraini Suwarsono, Erike Apri Lyanda Dilangga, Pad Gatot Sudiro Hendarto, Gatot Sudiro Herdato, M. Junus Didiek Hidayat Hidayat Krisandi, Grady Kusumajati, Pusparini Oktadoni Saputra, Oktadoni Rizki Putra Sanjaya Shinta Nareswari, Shinta Sinaga, Fransisca Sinaga, Fransisca Tarida Yuniar Soemarwoto, Retno Ariza S Soeprihatini, Retno Ariza Yeva Rosana