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All Journal Jurnal Biologi Tropis JURNAL FLOBAMORATA MENGABDI International Journal of Health Science Indonesian Journal of Global Health Research
Syahrir Syahrir
Universitas Nusa Cendana
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Public Health Social Sciences

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Secondary Metabolite Identification and Antibacterial Activity of Ethanol Extract of Coconut Husk (Cocos nucifera L.) Against Escherichia coli ATCC 25922 Bernadeta Videlsia Ikun; Syahrir Syahrir; Nimas Prita Rahajeningtyas Kusuma Wardani; Muhajirin Dean
International Journal Of Health Science Vol. 6 No. 1 (2026): March: International Journal of Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v6i1.6838

Abstract

Secondary metabolites are bioactive compounds commonly found in plants and have potential as natural antibacterial agents. Coconut coir (Cocos nucifera Linnaeus), an abundant agricultural by-product, is known to contain various secondary metabolites such as flavonoids, tannins, terpenoids, and phenolic compounds, which have been reported to possess antibacterial properties. Escherichia coli is a pathogenic bacterium that frequently causes human infections and has shown increasing resistance to several antibiotics, highlighting the need for alternative antibacterial sources. Inconsistencies in previous studies regarding the antibacterial activity of coconut coir against E. coli indicate the necessity for further investigation. This study aimed to identify the secondary metabolite content and evaluate the antibacterial activity of ethanol extract of coconut coir against Escherichia coli ATCC 25922. This study was an in vitro laboratory experimental study with a descriptive–experimental approach. Identification of secondary metabolites was conducted qualitatively using phytochemical screening of the ethanol extract of coconut coir. Antibacterial activity was assessed using the disc diffusion method with a post-test only control group design against Escherichia coli ATCC 25922. The phytochemical screening results demonstrated that the ethanol extract of coconut coir contained flavonoids, tannins, terpenoids, and polyphenols. However, the antibacterial activity test showed no inhibition zones at all tested concentrations of the ethanol extract against Escherichia coli ATCC 25922. These findings indicate that although the ethanol extract of coconut coir contains several secondary metabolites, it does not exhibit antibacterial activity against Escherichia coli ATCC 25922 when tested using the disc diffusion method.
Peningkatan Pengetahuan dan Keterampilan Tenaga Kependidikan Melalui Pelatihan Bantuan Hidup Dasar di Program Studi Pendidikan Dokter FKKH Universitas Nusa Cendana Nimas Prita Rahajeningtyas Kusuma Wardani; Deif Tunggal; Syahrir Syahrir; Insani Fitrahulil Jannah; Audrey Gracelia Riwu; Maria Laurenci Fany Permata Kale; Nurul Fatmawati Pua Upa; Cahyani Purnasari; Mathias Nathaniel Kolobani
Jurnal Flobamorata Mengabdi Vol. 3 No. 1 (2025): JURNAL FLOBAMORATA MENGABDI
Publisher : Program Studi Pendidikan Guru Sekolah Dasar, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Muhammadiyah Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51494/jfm.v3i1.2433

Abstract

Abstrak: Henti jantung merupakan kasus kegawatdaruratan medis dimana jantung berhenti berfungsi secara medadak sehingga menimbulkan gangguan hemodinamik tubuh hingga dapat menimbulkan kematian jika tidak ditangani segera. Tindakan bantuan hidup dasar (BHD) merupakan serangkaian tindakan pertolongan pertama yang dapat dilakukan untuk memulihkan fungsi pernapasan dan sirkulasi pada seseorang yang mengalami henti jantung. Pelatihan BHD pada tenaga kependidikan yang merupakan kelompok non-medis di lingkungan program studi Pendidikan dokter FKKH Universitas Nusa Cendana bertujuan untuk meningkatkan kapabilitas pegawai dalam melakukan pertolongan pertama serta meningkatkan kesiapsiagaan pegawai dalam kondisi kegawatdaruratan kejadian henti jantung terutama di lingkungan kerja. Metode yang digunakan adalah pelatihan kepada 20 tenaga kependidikan dengan menggabungkan teori, diskusi interaktif, serta praktik simulasi. Hasil dari pelatihan didapatkan peningkatan pengetahuan diukur dari nilai post-test yang jauh lebih baik dibandingkan nilai pre-test. Selain itu, didapatkan peningkatan keterampilan dan kepercayaan diri dari peserta dalam melakukan tindakan BHD pada kasus henti jantung. Kesimpulannya, kegiatan pelatihan BHD bagi tenaga kependidikan di lingkungan program studi Pendidikan Dokter, FKKH Universitas Nusa Cendana terbukti efektif dalam meningkatkan pengetahuan dan keterampilan peserta pelatihan.
Nurses' Experiences in Providing Palliative Care to Stroke Patients Yohanis Jowa Dairu; Maria Syelvrida Tumina; Syahrir Syahrir
Indonesian Journal of Global Health Research Vol. 7 No. 6 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i6.133

Abstract

Stroke is one of the main diseases that causes long-term disability and increases the need for palliative care. Nurses play a central role in providing palliative nursing care, especially in improving the quality of life of patients experiencing physical, psychological, social, and spiritual disorders. Exploring the experiences of nurses providing palliative care to stroke patients in the Garuda Ward of S.K. Lerik Regional General Hospital in Kupang City. This study used a qualitative method with a phenomenological approach. Data were obtained through in-depth interviews, using purposive sampling technique with 10 nurses as participants. The participant was selected based on inclusion criteria as follow: nurses who have experiences in palliative nursing care for stroke patients. We identified five main themes as follow: (1) Nurses have a good understanding of palliative care, (2) Patience and empathy as the main keys for nurses, (3) Professional responsibility and initiative of nurses, (4) Collaboration and initiatives in providing palliative care, (5 The need for palliative care competency development. Nevertheless, nurses demonstrated strong commitment and high empathy in providing holistic support for stroke patients.
Association of Patient Characteristics and Polypharmacy with the Potential for Drug Interactions among Hypertensive Patients at Bakunase Community Health Center Agatha Febryani Charmy Tanggung; Magdarita Riwu; Cahyani Purnasari; Syahrir Syahrir
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): Juli - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12884

Abstract

Chronic hypertension frequently has comorbidities, necessitating the use of several drugs (polypharmacy), which raises the possibility of drug interactions. This study aimed to determine the prevalence of polypharmacy, potential drug interactions, and the association between patient characteristics, polypharmacy, and potential drug interactions among hypertensive patients at Bakunase Primary Health Center. 572 hypertensive patients' medical data from January to December 2025 were used in this analytical observational study, which used a retrospective cross-sectional approach. Drugs.com® and Medscape® were used to identify potential drug interactions, and the Chi-square test was used to evaluate the results. According to the findings, 32.3% of patients had polypharmacy and 63.7% of patients had possible drug interactions. While polypharmacy was substantially linked to possible drug interactions (p = 0.001), age was significantly linked to both polypharmacy and potential drug interactions (p = 0.003). We conclude that among hypertension patients, age and polypharmacy are strongly linked to a higher likelihood of possible medication interactions.  
Co-Authors Agatha Febryani Charmy Tanggung Audrey Gracelia Riwu Bernadeta Videlsia Ikun Cahyani Purnasari Deif Tunggal Insani Fitrahulil Jannah Magdarita Riwu Maria Laurenci Fany Permata Kale Maria Syelvrida Tumina Mathias Nathaniel Kolobani Nimas Prita Rahajeningtyas Kusuma Wardani Nurul Fatmawati Pua Upa Yohanis Jowa Dairu