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The effect of addition protein, phosphatidylcholine, phosphatidylserine, and inulin on GFAP levels of acute ischemic stroke patients at Dr. Kariadi Hospital, Semarang Wahyuningrum, Diah Retno; Retnaningsih, Retnaningsih; Kartasurya, Martha Irene
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 9, No 2 (2021): Juni
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.9.2.184-197

Abstract

Background: The occurrence of ischemia causes a loss of energy to switch to anaerobic processes resulting in acidosis due to reduced Adenosina Triphosphate (ATP). This condition makes neuron cells apoptotic. Apoptotic of several biochemical substrates in the brain, such as Glial Fibrillary Acidic Protein (GFAP) exit into the circulatory system which is associated with dysbiosis through immunological pathways.Objectives: To determine the effect of giving enteral formula containing protein, phosphatidylcholine, phosphatidylserine, and inulin on GFAP levels in patients with acute ischemic stroke Dr. Kariadi Hospital.Materials and Methods: This study was done in a single-blind RCT. Eighteen ischemic stroke patients were randomly divided into intervention (9 subjects) and control groups (9 subjects). The intervention group received 69 g of the powdered enteral formula three times a day for seven days. The formula contained protein (15 g), phosphatidylcholine (128 mg),  phosphatidylserine (32 mg), and inulin (3 g). The subject who had diabetes mellitus received for 14 days at a dose of 34.5 g per day (7.5 g protein with additions 64mg phosphatidylcholine, 16mg phosphatidylserine, 1.5 g inulin). The control group received the standard enteral formula from the hospital, which contains (11.8 g protein without additions protein, phosphatidylcholine, phosphatidylserine, and inulin). GFAP levels by ELISA method (Enzyme-linked immunosorbent Assay) at pre and post-intervention.Results: There was a trend of decreasing GFAP levels before and after in the intervention group towards a better direction from 8.37±4.25 to 8.30±4.9 compared with the control group which experienced an increasing trend from 5.4±1.8 to 7.5±4. There was no significant difference in GFAP levels after intervention between groups (p = 0.7).Conclusions: The addition of protein, phosphatidylcholine, phosphatidylserine, and inulin had no significant effect on GFAP levels.
The Effect of Nutrition Education Using Leaflet Media on Knowledge of Meal Planning in Type II Diabetes Mellitus Outpatients at the Pasundan Health Center in Samarinda Devina Nur Astiza; Joko Cahyono; Diah Retno Wahyuningrum
Formosa Journal of Science and Technology Vol. 2 No. 7 (2023): July, 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v2i7.5262

Abstract

Diabetes mellitus is a degenerative disease that cannot be fully cured, but can be managed and controlled by the sufferer. The knowledge of a person with diabetes mellitus is greatly influenced by the information obtained, informative and interesting educational media is a very strong supporting factor in increasing knowledge quickly. The purpose of this study was to determine the effect of nutrition education using leaflet media on knowledge in type II diabetes mellitus outpatients at the Pasundan Health Center in Samarinda. The pre-experimental research design used the One Group Pretest-Postest design with 40 respondents using a purposive sampling technique. Data analysis used the Wilcoxon test with a value of p=0.000. The results showed that there was a difference in the average value of knowledge before and after being given nutrition education using leaflet media. So that there is an influence of nutrition education using leaflet media on the knowledge of type II diabetes mellitus outpatients.
STUDI PERBANDINGAN HATI AYAM, KALAKAI (STENOCHLAENA PALUTRIS) DAN TEPUNG KEDELAI HITAM (GLYCINE SOJA) TERHADAP ZAT GIZI PROTEIN DAN LEMAK SERTA DAYA TERIMA MUTU PATTY BURGER NON MEAT Mutiara Azzahra Asrivananda; Rinten Anjang Sari; Diah Retno Wahyuningrum
Jurnal Kesehatan Tambusai Vol. 4 No. 4 (2023): DESEMBER 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v4i4.19413

Abstract

Perkembangan industri makanan terus berkembang karena semakin banyaknya konsumen yang sadar akan pentingnya gaya hidup sehat dan berkelanjutan. Produk makanan non meat menjadi salah satu bagian dari perkembangan industri makanan yang menciptakan makanan sehat dan bergizi. Penelitian ini bertujuan untuk mengetahui hasil perbandingan hati ayam, kalakai dan tepung kedelai hitam terhadap zat gizi protein dan lemak serta daya terima mutu patty burger non meat. Penelitian ini adalah penelitian eksperimental dengan rancangan acak lengkap pada 5 perlakuan dan 3 pengulangan. Pengujian kadar protein menggunakan metode Kjedahl, kadar lemak menggunakan metode Soxhlet, dan uji daya terima menggunakan responden 25 panelis tidak terlatih. Analisis kuantitatif menggunakan SPSS 20 uji ANOVA taraf 5% dilanjutkan dengan uji BNT dan uji Kruskall Wallis dilanjutkan dengan uji Mann Whitney. Hasil uji kandungan protein patty burger non meat adalah 17,24% - 19,23%, kadar lemak 12,28% - 15,44%. Hasil perlakuan terbaik yaitu formulasi 2 dengan proporsi hati ayam 70%, kalakai 15%, dan tepung kedelai hitam 15%. Patty burger non meat mengalami peningkatan kadar protein dan kadar lemak seiring dengan proporsi tepung kedelai hitam dan kalakai yang meningkat meskipun proporsi hati ayam menurun. Proporsi hati ayam, kalakai, dan tepung kedelai hitam dengan kesenjangan tinggi memberikan perbedaan terhadap warna, rasa, dan tekstur patty.  
The Effectiveness of Nutrition Education about Stunting Using Video Media on The Knowledge and Attitudes of Mothers of Toddlers Naomi Burah; Sepsina Reski; Diah Retno Wahyunigrum; Joko Cahyono
Journal of Health and Nutrition Research Vol. 3 No. 1 (2024)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v3i1.202

Abstract

Stunting is still a global health emergency, threatening children's health and productivity in the future. Stunting in children begins in the family environment. Mothers contribute fully to optimal child growth and development. This study aims to determine the effectiveness of nutrition education about stunting using video media on the knowledge and attitudes of mothers under five. A quasi-experimental study with a pre-post test approach with a control group design was conducted in February – April 2023 at the Teluk Lingga Sangatta Health Center, East Kutai, East Kalimantan. A total of 36 samples were involved in this study by purposive sampling by taking into account inclusion and exclusion criteria. Data were analysed using paired t-tests and independent t-tests. There were differences in knowledge before and after being given nutrition education videos with a value of p-0.000 and differences in attitudes before and after being given nutrition education videos with a value of p-0.000. There are differences in knowledge before and after nutrition education with leaflet p-0.000. There are differences in the attitude of mothers of toddlers before and after nutrition education with leaflet p-0.000. Nutrition education videos are more effective in increasing knowledge compared to the p-0.000 leaflet. Nutrition education videos are more effective in improving attitudes compared to leaflet p-0.001. Nutrition education videos about stunting are more effective in increasing knowledge and attitudes about stunting.
PENGARUH EDUKASI GIZI MENGGUNAKAN MEDIA SCRAPBOOK TERHADAP PENGETAHUAN PERENCANAAN MAKANAN DAN TINGKAT KONSUMSI IBU HAMIL ANEMIA DI WILAYAH KERJA PUSKESMAS HARAPAN BARU: PENGARUH EDUKASI GIZI MENGGUNAKAN MEDIA SCRAPBOOK TERHADAP PENGETAHUAN PERENCANAAN MAKANAN DAN TINGKAT KONSUMSI IBU HAMIL ANEMIA DI WILAYAH KERJA PUSKESMAS HARAPAN BARU Hana Nur'faizah; Joko Cahyono; Diah Retno Wahyuningrum
HSG (Health Science Growth) Journal Vol 8 No 01 (2023): Health Science Growth (HSG) Journal
Publisher : Fakultas Ilmu Kesehatan Unsika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/hsg.v8i01.9716

Abstract

Anemia in pregnant women can occur due to a doubling of iron requirements due to increased blood volume and fetal growth. Providing nutrition education is an alternative that can provide basic knowledge needs for pregnant women and is more effective by using scrapbook media. The purpose of this study was to determine the effect of nutrition education using scrapbook media on food planning knowledge and consumption levels of anemic pregnant women in the Harapan Baru Health Center working area. Pre-experiment research with One Group Pretest-Posttest design. The sampling technique used purposive sampling consisting of 18 respondents. Data collection using questionnaires and 24-hour food recall interviews for 3 non-consecutive days. Univariate analysis technique with descriptive and bivariate analysis with Wilcoxon test. The results showed that there was an effect of nutrition education using Scrapbook media on the food planning knowledge of anemic pregnant women (p = 0.000) and there was no effect of nutrition education using Scrapbook media on the consumption levels of anemic pregnant women energy, protein, fat, carbohydrates respectively (p = 0.131; p = 0.257; p = 0.114; p = 0.59). Conclusion: There is an effect of nutrition education using scrapbook media on the food planning knowledge of anemic pregnant women and there is no effect of nutrition education using scrapbook media on the consumption level of anemic pregnant women in the Harapan Baru Health Center working area.
Hubungan Tingkat Kepuasan Penyajian dan Pelayanan Makanan Terhadap Sisa Makanan Pasien Rawat Inap Marina Marina; Farida Nailufar; Diah Retno Wahyunigrum
Jurnal Gizi Kerja dan Produktivitas Vol 5, No 1 (2024): May
Publisher : Fakultas Kedokteran Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/jgkp.v5i1.25136

Abstract

Tujuan penelitian yaitu untuk menganalisis hubungan tingkat kepuasan penyajian dan pelayanan makanan terhadap sisa makanan pasien rawat inap di RS Pratama Gerbang Sehat Mahulu Kabupaten Mahakam Ulu. Jenis penelitian adalah observasional analitik dengan menggunakan pendekatan Cross Sectional. Populasi dalam penelitian adalah seluruh pasien perempuan dewasa, laki-laki dewasa dan Kebidanan rawat inap di RS Gerbang Sehat Mahulu dengan jumlah rata-rata pasien 60 orang (pasien dewasa) perbulan. Variabel independen yaitu kepuasan penyajian dan pelayanan makanan, sedangkan variabel dependen adalah sisa makanan pasien dengan menggunakan metode taksiran visual comstock. Analisis data yaitu menggunakan SPSS dan uji statistik Che-Square dengan tingkat signifikansi p < 0.05. Hasil penelitian yaitu tingkat kepuasan penyajian makanan yaitu tidak ada hubungan antara ketepatan waktu pemberian makanan dengan nilai p = 0,428, variasi menu dengan nilai p = 0,742, tekstur makanan dengan nilai p = 0,428 dan cara penyajian makanan dengan nilai p = 0,428 terhadap sisa makanan pasien. Terdapat hubungan antara rasa makanan dengan sisa makanan pasien dengan nilai p = 0,031. Tingkat kepuasan pelayanan makanan yaitu tidak ada hubungan antara sikap petugas penyajian makanan dengan nilai p = 0,575 dan peralatan saji makanan dengan nilai p = 0,914 terhadap sisa makanan pasien. kesimpulan yaitu tingkat kepuasan penyajian makanan pasien rawat inap di rumah sakit hanya dipengaruhi oleh rasa makanan. Pasien yang merasa puas dengan rasa makanan cenderung menyisakan makanan lebih sedikit. Sementara itu, tingkat kepuasan pelayanan makanan pasien rawat inap di rumah sakit tidak dipengaruhi oleh ketepatan waktu pemberian makanan, variasi menu, tekstur makanan, cara penyajian makanan, sikap petugas penyajian makanan, dan peralatan saji makanan
Analisis perbedaan indeks glikemik dan beban glikemik pada berbagai jenis minuman kekinian: Peningkatan risiko metabolik Aisyah Luthfia Agung; Elvi Susanti; Diah Retno Wahyuningrum; Joko Cahyono
Jurnal SAGO Gizi dan Kesehatan Vol 6, No 1 (2025): April
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v6i1.2163

Abstract

Background: Indonesia ranks third highest in consumption of contemporary drinks in Southeast Asia. It contains high sugar levels and if consumed excessively can significantly increase blood glucose. Glycemic Index (GI) and Glycemic Load (GL) are ways to determine the rising of blood sugar levels.Objectives: To determine the differences in glycemic index and glycemic load of various contemporary drinks.Methods: The type and design of the study used was quasi-experimental with non-equivalent control group design. Quasi-experimental is an experimental study consisting of a treatment group and a control group. Respondents were divided into 4 groups (control, boba, thai tea, and coffee latte) and consisted of 8 people in each group. Blood glucose examination was carried out through the capillary at minutes 0, 30, 60, 90, and 120 to assess the blood glucose response. Data were analyzed using the One Way Anova test and the Post Hoc Tukey follow-up test.Results: GI boba, thai tea, and coffee latte were respectively (62,20%; 69,,13%; 99,97%) and GL respectively (27,36%; 30,62%; 44,77%). Boba and Thai tea are classified as medium IG with high BG, while coffee latte is classified as high IG with high BG. A significant difference was shown between the IG of coffee latte and the control (0,008) and the BG of the three contemporary drinks with the control (0,000). Conclusion: There is no difference in meaning between GI and GL of the three types of contemporary drinks. It is recommended that contemporary drinks are not consumed every day.
COMPARISON OF THE EFFECTIVENESS OF FERMENTED TIWAI ONIONS AND LANANG ONIONS ON CHOLESTEROL LEVELS IN SPRAGUE DAWLEY HYPERCHOLESTEROLEMIA RATS Utami, Kurniati Dwi; Wahyuningrum, Diah Retno; Naimatur, Rizqi
Jurnal Kesehatan Tambusai Vol. 6 No. 2 (2025): JUNI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i2.43733

Abstract

This study was a pure experimental study using a control group. The experimental animals used were two-month-old Sprague Dawley rats. The four groups of rats were given a high-cholesterol diet with the addition of egg yolk to the feed for two weeks. After the rats experienced hypercholesterolemia, the rats were divided into four groups. The first group was the control group given distilled water. The second group was given simvastatin at a dose of 15 mg/kgBW. The third group was given fermented shallots at a dose of 200 mg/kgBW, and the fourth group was given fermented shallots at a dose of 200 mg/kgBW. Each group consisted of five rats. The results of the ANOVA test showed a significant difference in cholesterol levels between groups with a p value = 0.00. The Tukey HSD further test showed a difference in mean HDL between the control group and the group given simvastatin. However, no significant difference was found in cholesterol levels between the groups given fermented shallots and fermented shallots. The groups given fermented shallots and lanang shallots had lower mean cholesterol compared to the control and simvastatin groups. The conclusion of this study is that the administration of fermented tiwai and lanang onions both showed effectiveness in lowering blood cholesterol levels in rats with hypercholesterolemia, as effective as simvastatin. This finding shows the potential of fermented onions as an alternative herbal therapy in managing high cholesterol.
The Relationship Between Sodium, Potassium Intake and Nutritional Status with Blood Pressure in Hypertension Sufferers in the Loa Janan Community Health Center Working Area Aulia, Desy; Saraheni; Wahyuningrum, Diah Retno
Indonesian Journal of Advanced Research Vol. 2 No. 10 (2023): October 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijar.v2i10.6203

Abstract

Riskesdas data 2018 shows that the prevalence of hypertension in the elderly population >18 years in Indonesia based on national measurements is 34.11%. The aim of the research was to determine the relationship between sodium, potassium intake and nutritional status with blood pressure in hypertension sufferers in the Loa Janan Community Health Center working area. The research method was cross sectional with accidental sampling technique consisting of 45 respondents. Data collection technique using 24 hour food recall interviews for 2 days. Chi square test data analysis technique. The results of the chi square test showed that there was a significant relationship between sodium intake and blood pressure (p=0.000), there was no significant relationship between potassium intake and blood pressure (p=0.509) and there was a significant relationship between nutritional status and blood pressure (p =0.007). Conclusion: There is a significant relationship between sodium intake and blood pressure, and there is no significant relationship between potassium intake and blood pressure and there is a significant relationship between nutritional status and blood pressure in the Loa Janan Community Health Center working area.
Kualitas Lingkungan Fisik Rumah Kasus Malaria Berbasis Pendekatan Spasial Hidayati, Fitni; Ayunda, Kalasta; Wahyuningrum, Diah Retno; Rahmadini, Fathia
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 16, No 3 (2025): Juli-September 2025
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf16301

Abstract

Kaligesing is a malaria-endemic area in Purworejo Regency that has experienced a significant increase in cases in the past two years. The quality of the home environment is suspected to be a significant factor influencing the spread of this disease. This study aimed to spatially map the physical environmental quality of homes in the Kaligesing area and identify villages with the highest environmental risk levels for the potential spread of malaria. This study used an observational approach with data collection through field surveys of 10 houses in each village. House coordinates were taken using a Garmin Map 78S GPS, then analyzed spatially using ArcMap 10.3 software. Environmental parameters observed included the physical condition of buildings that have the potential to become habitats for Anopheles vectors. The results showed variations in environmental quality risk levels between villages. Several villages showed a high accumulation of physical environmental risks, particularly in the parameters of ventilation without wire mesh, the presence of bushes around houses, and the condition of non-permanent house walls. Villages with the highest risk were identified through the integration of attribute and spatial data. Sudorogo Village was identified as a village with high-risk environmental quality, which is in line with the highest number of malaria cases in the region. It was concluded that spatial mapping provides accurate visualization for identifying priority villages in malaria control efforts.Keywords: spatial mapping; environmental quality; malaria; geographic information systems ABSTRAK Kaligesing merupakan wilayah endemis malaria di Kabupaten Purworejo yang mengalami peningkatan kasus signifikan dalam dua tahun terakhir. Kualitas lingkungan rumah diduga menjadi salah satu faktor penting yang mempengaruhi penyebaran penyakit ini. Penelitian ini bertujuan untuk memetakan kualitas lingkungan fisik rumah secara spasial di wilayah Kaligesing serta mengidentifikasi desa dengan tingkat risiko lingkungan tertinggi terhadap potensi penyebaran malaria. Penelitian ini menggunakan pendekatan observasional dengan pengambilan data melalui survei lapangan pada 10 rumah pada masing-masing desa. Titik koordinat rumah diambil menggunakan GPS Garmin Map 78S, kemudian dianalisis secara spasial menggunakan perangkat lunak ArcMap 10.3. Parameter lingkungan yang diamati meliputi kondisi fisik bangunan yang berpotensi menjadi habitat vektor Anopheles. Hasil penelitian menunjukkan adanya variasi tingkat risiko kualitas lingkungan antar desa. Beberapa desa menunjukkan akumulasi risiko lingkungan fisik yang tinggi, terutama pada parameter ventilasi tanpa kawat kasa, keberadaan semak-semak di sekitar rumah, dan kondisi dinding rumah yang tidak permanen. Desa dengan risiko tertinggi teridentifikasi melalui integrasi data atribut dan spasial. Desa Sudorogo teridentifikasi sebagai desa dengan kualitas lingkungan berisiko tinggi, yang sejalan dengan jumlah kasus malaria tertinggi di wilayah tersebut. Disimpulkan bahwa Pemetaan spasial memberikan visualisasi yang akurat untuk mengidentifikasi desa prioritas dalam upaya pengendalian malaria.Kata kunci: pemetaan spasial; kualitas lingkungan; malaria; sistem informasi geografis