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Pengaruh Pemberian Ekstrak Daun Sirsak (Annona Muricata L.) Terhadap Fungsi Pankreas Dan Gambaran Histopatologi Pankreas Tikus Putih Galur Wistar Jantan yang Mengalami Diabetes Melitus Nazar, Hasrul; Loren, Jeff; Siregar, Lisdawaty
JURNAL PENELITIAN PENDIDIKAN, PSIKOLOGI DAN KESEHATAN (J-P3K) Vol 6, No 2 (2025): J-P3K
Publisher : Yayasan Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-p3k.v6i2.759

Penelitian ini bertujuan untuk menyelidiki pengaruh pemberian ekstrak daun sirsak (Annona muricata L.) terhadap fungsi pankreas dan gambaran histopatologi pankreas pada tikus putih galur Wistar jantan yang menderita diabetes melitus. Diabetes diinduksi dengan pemberian alloksan, dan tikus dibagi menjadi beberapa kelompok: kelompok kontrol, kelompok diabetes, dan kelompok perlakuan yang menerima dosis ekstrak daun sirsak yang berbeda. Fungsi pankreas dievaluasi melalui pengukuran kadar glukosa darah, dan pemeriksaan histopatologi pankreas dilakukan menggunakan pewarnaan hematoksilin dan eosin. Hasil penelitian menunjukkan bahwa pemberian ekstrak daun sirsak secara signifikan menurunkan kadar glukosa darah dan memperbaiki gambaran histopatologi pankreas, yang menunjukkan adanya efek protektif terhadap fungsi pankreas pada tikus diabetes. Hal ini menunjukkan bahwa ekstrak daun sirsak berpotensi memiliki manfaat terapeutik dalam pengelolaan diabetes melitus.

Analysis of factors influencing re-visit intention of diabetes mellitus patients at dr. Pirngadi General Hospital Loren, Jeff; Zannah, Rafika; Hutauruk, Magdalena Julianni; Kuswani, Lili; Delfian, Taufik; Haryadi, Haryadi; Lumban Tobing, Andrico Napolin; Sopacua, Erwin; Arviandi, Rizki; Cisca, Anita Merry; Nadapdap, Faskanita Maristella; Putra, Kriswandy
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7444

Diabetes mellitus is a non-communicable disease that requires a long treatment so that patients have to take medication or visit the hospital more often, interest in repeat visits is a behavior that appears in response to objects that indicate a customer's desire to make a repeat purchase. The aim of the study was to find out whether the factors that determine interest in returning to diabetes mellitus patients at Pirngadi Hospital in Medan City in 2023. The research method uses a correlative descriptive design with a cross-sectional approach. The results showed that most of the respondents were male, namely 23 (51.1%), the education level of respondents who were high and medium had the same proportion, namely 18 (40%), the employment status of respondents was 30 (66.7%) working. Quality of service as many as 33 (73.3%) and as many as 28 (62.2%) families get high support. The results of the statistical chi-square test found that there was no significant relationship between gender and intention to revisit (p=0.155), there was no relationship between education and intention to revisit (p=0.371), there was no relationship between work and intention to revisit (p=0.828), there is a relationship between quality of service and interest in repeat visits (p=0.000). There is no relationship between family support and interest in repeat visits (p=0.000). This research is expected to be an evaluation material in improving health services related to the determinants of interest in repeat visits of patients with diabetes mellitus.

Histopathological characteristics of soft tissue tumors at Madani General Hospital Nasution, Prenan Dito Perdana; Lina, Juliana; Wardhani, Fiska Maya; Loren, Jeff; Muchtar, Muhammad Arafat; Iskandar, Ari Rahman
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5677

Benign tumors were more common than malignant tumors, with a ratio of 1:100. However, in 2019, approximately 13,000 cases of malignant tumors were reported in the United States. Based on data from Cancer Referral Hospitals in Indonesia, soft tissue sarcomas were among the ten most common cancers in 2013, with approximately 75% of cases occurring in the extremity region. This study aimed to describe the histopathological examination results of patients with soft tissue tumors at the Madani General Hospital, Medan City. This study used a retrospective descriptive design by collecting data from the medical records of patients who underwent histopathological examination at the Anatomical Pathology Laboratory of Madani General Hospital (period 2018-2022). Data were analyzed based on the distribution of cases according to age, sex, and tumor type. The results showed that soft tissue tumors were most prevalent in the 41-50 age group with 30 patients (20.3%), the majority were female with 85 patients (57.4%), and based on histopathological diagnosis, lipoma was the most common type of tumor found in 70 patients (47.3%). All cases studied were benign tumors, with a total of 148 patients (100%).

Analysis of factors influencing re-visit intention of diabetes mellitus patients at dr. Pirngadi General Hospital Loren, Jeff; Zannah, Rafika; Hutauruk, Magdalena Julianni; Kuswani, Lili; Delfian, Taufik; Haryadi, Haryadi; Lumban Tobing, Andrico Napolin; Sopacua, Erwin; Arviandi, Rizki; Cisca, Anita Merry; Nadapdap, Faskanita Maristella; Putra, Kriswandy
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7444

Diabetes mellitus is a non-communicable disease that requires a long treatment so that patients have to take medication or visit the hospital more often, interest in repeat visits is a behavior that appears in response to objects that indicate a customer's desire to make a repeat purchase. The aim of the study was to find out whether the factors that determine interest in returning to diabetes mellitus patients at Pirngadi Hospital in Medan City in 2023. The research method uses a correlative descriptive design with a cross-sectional approach. The results showed that most of the respondents were male, namely 23 (51.1%), the education level of respondents who were high and medium had the same proportion, namely 18 (40%), the employment status of respondents was 30 (66.7%) working. Quality of service as many as 33 (73.3%) and as many as 28 (62.2%) families get high support. The results of the statistical chi-square test found that there was no significant relationship between gender and intention to revisit (p=0.155), there was no relationship between education and intention to revisit (p=0.371), there was no relationship between work and intention to revisit (p=0.828), there is a relationship between quality of service and interest in repeat visits (p=0.000). There is no relationship between family support and interest in repeat visits (p=0.000). This research is expected to be an evaluation material in improving health services related to the determinants of interest in repeat visits of patients with diabetes mellitus.

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