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Mekanisme Escherichia coli dalam Patogenesis Infeksi Saluran Kemih: Literature Review Nursifa, Anis Fauziah; Hafiz, Mochammad Ikhbar; Amalia, Najwa Syifa; Maulidina, Nayla Fasya; Choironissa, Nazwa Shifa; Salma, Nisrina Nabila; Putri, Rd. Natasya Aurellia; Ringo, Regita Ayu Revalina Siringo; Puspita, Reva Sri; Rosdiani, Rosdiani; Sopiah, Popi
Jurnal Penelitian Inovatif Vol 5 No 2 (2025): JUPIN Mei 2025
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jupin.1480

Abstract

Infeksi Saluran Kemih (ISK) merupakan salah satu infeksi bakteri yang paling umum terjadi dan dapat menyebabkan komplikasi serius apabila tidak ditangani secara tepat. Escherichia coli, khususnya Uropathogenic Escherichia coli (UPEC), merupakan patogen utama penyebab ISK dengan berbagai mekanisme patogenik. Studi ini bertujuan untuk meninjau secara sistematis mekanisme patogenesis E. coli dalam menyebabkan ISK. Metode yang digunakan adalah scoping review terhadap literatur yang dipublikasikan antara tahun 2016 hingga 2025, dengan sumber data dari Google Scholar, ScienceDirect, dan Semantic Scholar. Seleksi dilakukan berdasarkan kriteria PICO: Population (penderita ISK), Intervention (Escherichia coli), Comparison (tidak ada), Outcome (mekanisme patogenesis). Sebanyak tujuh artikel yang relevan berhasil diseleksi dan dianalisis. Hasil kajian menunjukkan bahwa UPEC merupakan penyebab dominan ISK, dengan kemampuan adhesi melalui pili sebagai faktor virulensi utama yang memungkinkan bakteri melekat pada sel epitel saluran kemih. Mekanisme patogenesis melibatkan proses kolonisasi, adhesi, invasi, replikasi, serta aktivasi respons imun dan inflamasi. Kajian ini memberikan kontribusi penting dalam memahami strategi patogenik E. coli, yang dapat mendukung pengembangan pendekatan diagnostik dan terapeutik yang lebih efektif dalam pengelolaan ISK.
PROSES KEPERAWATAN: TAHAP INTERVENSI DALAM UPAYA PENCEGAHAN KOMPLIKASI PADA PASIEN HIPERTENSI Nurfadhilah, Naila; Salma, Nisrina Nabila; Maliha, Alya Rafeyfa; Rifqi, Tiara; Puspita, Reva Sri; Ridwan, Heri
JURNAL KESEHATAN INDRA HUSADA Vol 13 No 1 (2025): Juni 2025
Publisher : SEKOLAH TINGGI ILMU KESEHATAN INDRAMAYU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36973/jkih.v13i1.733

Abstract

Hypertension is a chronic non-communicable disease with an increasing global and national prevalence. It is often referred to as a silent killer because it typically shows no symptoms until complications arise. Preventing complications in hypertensive patients can be achieved through nursing interventions that are not only procedural but also foster awareness, motivation, and active patient involvement. However, the effectiveness of such interventions in changing patient behavior remains relatively low. This study aims to examine the nursing intervention process as an effort to prevent complications in patients with hypertension. This research used a literature review design with data collected from Google Scholar, PubMed, and Semantic Scholar. The keywords used were “Hypertension,” “Complication prevention,” and “Nursing intervention.” Article selection was guided by the PRISMA framework and included articles written in English or Indonesian, relevant to the topic, full-text, open-access, and published within the last five years. The findings identified five main categories of nursing interventions: education and lifestyle modification, physical activity, non-pharmacological relaxation therapy, complementary therapies such as herbal remedies and acupuncture, and regular monitoring and evaluation. Comprehensive and integrated interventions have been shown to improve patient knowledge, adherence, and quality of life, while also reducing the risk of complications. Conclusion: Holistic nursing interventions play a critical role in preventing hypertension-related complications. Nurses hold a strategic position in designing and implementing effective interventions to improve patient health outcomes.