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Journal : Proceeding of International Conference Health, Science And Technology (ICOHETECH)

Safety of Rivaroxaban For Prophylaxis Vein Thrombosis Post Total Hip and Knee Replacement Luthfiyanti, Niken; Jayak Pratama, Kharisma; Noviana, Noviana
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2024: Proceeding of the 5th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v5i1.4193

Abstract

Orthopaedic surgery such as surgery on the pelvis and knee bones has a high risk of developing Deep Vein Thromoembolism (DVT), especially in patients with hypercoagulability. Venous thromboembolism is the main cause of morbidity and mortality in orthopedic patients that can be prevented using thromboprophylaxis, but on the other hand is related to the risk of bleeding side effects. The study aimed to evaluate the safety of oral Rivaroxaban prophylaxis in patients after Total Hip and Knee Replacement. This research applied cross sectional technique. Retrospective data were taken from the medical records of Dr. Moewardi Surakarta, period January 2023- July 2024. The data taken are secondary data from the patient's medical record by recording clinical symptoms that appear. Rivaroxaban safety evaluation includes the incidence rate of bleeding as well as the factors that influence the occurrence of bleeding. A total of 38 patients met the inclusion criteria of the study. Bleeding occurred in 4 cases (10.5%). Factors that affect the incidence of bleeding renal failure (p = 0.001). Monitoring of Rivaroxaban side effects is indispensable. Pharmaceuticals can play an important role in monitoring and preventing the occurrence of bleeding by paying attention to risk factors, especially kidney failure.
FORMULATION AND ACTIVITY TESTS OF ANTI-ACNE TONER ESSENTIAL OIL OF RED BETEL LEAF (Piper crocatum) Riska Permata, Bangkit; Jayak Pratama, Kharisma; Nurul Kotimah, Mei Ika
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2023: Proceeding of the 4th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v4i1.3409

Abstract

Red betel leaf (Piper crocatum) is a plant that can be used as an antibacterial. Red betel leaves contain flavonoids, alkaloids, tannins, and essential oils which are thought to be used as antimicrobials. The purpose of this study was to determine the antibacterial activity of red betel leaf (Piper crocatum) essential oil facial toner as an anti-acne toner against Propionibacterium acnes bacteria. Red betel leaf is distilled to obtain essential oil, then tested for organoleptic, specific gravity, pH, viscosity, solubility in alcohol. Making facial toner preparations using concentrations of 10%, 20% and 30%. The results of the formula were then subjected to physical quality tests including organoleptic tests, pH tests, viscosity, anti-irritation tests, hedonic tests and activity tests against Propionibacterium acnes bacteria. Toner preparation activity test results obtained concentrations of 10% 9.2 mm, 20% 11.26 mm, 30% 13.46 mm. Red betel leaf essential oil toner can inhibit the growth of Propionibacterium acnes bacteria with the highest concentration of 30% obtained inhibition of 13.46 mm in the strong category.
Safety of Rivaroxaban For Prophylaxis Vein Thrombosis Post Total Hip and Knee Replacement Luthfiyanti, Niken; Jayak Pratama, Kharisma; Noviana, Noviana
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2024: Proceeding of the 5th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v5i1.4193

Abstract

Orthopaedic surgery such as surgery on the pelvis and knee bones has a high risk of developing Deep Vein Thromoembolism (DVT), especially in patients with hypercoagulability. Venous thromboembolism is the main cause of morbidity and mortality in orthopedic patients that can be prevented using thromboprophylaxis, but on the other hand is related to the risk of bleeding side effects. The study aimed to evaluate the safety of oral Rivaroxaban prophylaxis in patients after Total Hip and Knee Replacement. This research applied cross sectional technique. Retrospective data were taken from the medical records of Dr. Moewardi Surakarta, period January 2023- July 2024. The data taken are secondary data from the patient's medical record by recording clinical symptoms that appear. Rivaroxaban safety evaluation includes the incidence rate of bleeding as well as the factors that influence the occurrence of bleeding. A total of 38 patients met the inclusion criteria of the study. Bleeding occurred in 4 cases (10.5%). Factors that affect the incidence of bleeding renal failure (p = 0.001). Monitoring of Rivaroxaban side effects is indispensable. Pharmaceuticals can play an important role in monitoring and preventing the occurrence of bleeding by paying attention to risk factors, especially kidney failure.