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All Journal Lumbung Farmasi : Jurnal Ilmu Kefarmasian JES-TM Social and Community Service
Awilda, Pertiwi
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Decision Sciences, Operations Research & Management Education Engineering Health Professions Medicine & Pharmacology Other

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Uji Aktivitas Antipembekuan Darah dan Docking dari Daun Kaki Unta (Waltheria indica L.) Awilda, Pertiwi; Bawaihi, Bawaihi; Jiddan, Muhammad Jayyid; Mildawati, Ratna; Hadi, Samsul
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 2 (2025): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i2.31402

Abstract

Di Indonesia, prevalensi penyakit jantung koroner (PJK) adalah 1,5% di semua kelompok umur, sehingga masih menjadi masalah serius. Jika berbicara tentang penyakit kardiovaskular, PJK berada di urutan teratas. Tujuan dari penelitian ini adalah uji aktivitas W. indica berkaitan dengan kemampuan sebagai antikoagulan. Darah tikus digunakan untuk teknik pengujian in vitro, sedangkan waktu pendarahan tikus diukur untuk pengujian in vivo, dengan menggunakan perangkat lunak PLANT dalam docking, penelitian insilico digunakan untuk mengidentifikasi senyawa dari W. indica yang mungkin memiliki sifat antikoagulan, Discovery Studio kemudian digunakan untuk mengidentifikasi residu yang terlibat dalam interaksi dan skor doking digunakan dalam analisis data. Hasil uji in vitro untuk ekstrak etanol menunjukkan adanya koagulasi pada menit ke-30, fraksi n-heksana pada menit ke-10, fraksi etil asetat dan n-butanol pada menit ke-60, dan pada uji in vivo pendarahan hingga 349 ± 23 detik untuk dosis 100 mg/kg BB, 425 ± 27 detik untuk dosis 200 mg/kg BB, dan 546 ± 34 detik untuk dosis 300 mg/kg BB, hal ini lebih baik dari pada kontrol, dan dengan docking mengungkapkan bahwa senyawa yang berpotensi dalam  pengujian ini adalah quercetin. Kesimpulannnya  W. indica  berpotensi sebagai antipembekuan  darah
Education on live pharmacy plants and the use of small land in Sungai Musang Village Awilda, Pertiwi; Chairul; Nurwahida; Nurrahmah, Sheila; Rizwarini, Siti Rahma; Bawaihi
Journal of Social and Community Service Vol. 2 No. 2 (2023): July 2023
Publisher : Faculty of Engineering University of Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jestmc.v2i2.161

Abstract

Knowledge about the use of yard land for live pharmacy plants or family medicinal plants (toga) is not yet well understood by the people of Sungai Musang village, which is shown by the yard land around people's houses which has not been planted with live pharmacy plants.  The aim of this service is to provide education to the public regarding live pharmacy plants and to be able to utilize the narrow land around the house to plant live pharmacy plants. The method given is a lecture about the meaning of a living pharmacy, types of plants, the benefits of a living pharmacy, and how to process medicinal plants. Followed by questions and answers and distributing leaflets to participants. Another activity is to provide an example of making a living pharmacy for a narrow area from wooden shelves and mini pots. Participants were very enthusiastic about taking part in this activity, most of the participants gained knowledge about living pharmacies and their uses and were expected to be motivated to make their own in their own yards.
Education on the Utilization of Broccoli (Brassica oleracea L. Var italica) as a Preventive Measure for Myopia at SMA Negeri 2 Banjarmasin Awilda, Pertiwi; Chairul; Nurwahida; Nurrahmah, Sheila; Rahima, Siti; Kartini
Journal of Social and Community Service Vol. 1 No. 3 (2022): July 2022
Publisher : Faculty of Engineering University of Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jestmc.v1i3.190

Abstract

Myopia is a growing public health issue worldwide, including in Indonesia. Preventive measures include educating the public about the importance of nutrition for eye health. This community service program was conducted at SMA Negeri 2 Banjarmasin in April 2022, aiming to educate students about the benefits of broccoli (Brassica oleracea L. var italica) as an essential nutritional source for preventing myopia. Broccoli is rich in vitamin C, lutein, zeaxanthin, and beta-carotene, which are known to benefit eye health. The program utilized methods such as pre-tests, interactive educational sessions, broccoli preparation demonstrations, and post-tests to evaluate knowledge improvement. Results showed a significant increase in students' understanding of broccoli's benefits for eye health, with average pre-test scores of 56.7 rising to 85.4 in the post-test.
Co-Authors Bawaihi Bawaihi Bawaihi Chairul Jiddan, Muhammad Jayyid KARTINI Mildawati, Ratna Nurrahmah, Sheila Nurwahida Rahima, Siti Rizwarini, Siti Rahma Samsul Hadi