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All Journal Lumbung Farmasi : Jurnal Ilmu Kefarmasian PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Lentera Innovative: Journal Of Social Science Research Business and Economic Publication Journal of Social Science and Multidisciplinary Analysis Gotong Royong Interaksi : Jurnal Pengabdian Kepada Masyarakat International Journal of Contemporary Sciences (IJCS) Journal of Community Service for Health Multicore International Journal of Multidisciplinary (MIJM) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service
Mildawati, Ratna
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Asistensi Penyusunan Naskah Proposal Penelitian Dan Pengabdian Masyarakat Dengan Metode Lgd (Leaderless Group Discussion) Di Universtias Kadiri Prasetyawan, Fendy; Saristiana, Yuneka; Dhafin, Anis Akhwan; Mildawati, Ratna; Muslikh, Faisal Akhmal; Ariawan, Wahyu
Gotong Royong Vol. 1 No. 1 (2024)
Publisher : CV. Akira Java Bulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63935/gr.v1i1.16

Abstract

The assistance program for drafting research and community service proposals using the Leaderless Group Discussion (LGD) method at Universitas Kadiri aims to enhance the capacity of lecturers and students in producing high-quality and relevant proposals. The LGD method allows each participant to actively engage in discussions without a dominant leader, fostering involvement and constructive collaboration. The program includes preparation, workshop implementation, proposal evaluation, and follow-up stages. Results indicate significant improvements in problem formulation clarity, methodological accuracy, and proposal consistency. Additionally, active participant involvement and the development of collaborative skills were achieved, strengthening an inclusive discussion culture within the academic environment. Evaluations show that the LGD method effectively enhances academic and professional quality, despite challenges in ensuring deep understanding of topics and methodologies. With support from the Universitas Kadiri's Center for Educational Development and Quality Assurance (LP3M) team, this program successfully met its objectives and provides a strong foundation for similar future activities. The outcomes of this program are expected to contribute to improving the quality of innovative and impactful research and community service.
The Effect Of Giving Educative Videos About Diabetic Foot Gymnastics On The Implementation Of Foot Exercises In Patients With Type 2 Diabetes Mellitus At Chania Care Center Kediri District Juwariyah, Titik; Winarni, Jajuk; Lailaturohmah, Lailaturohmah; Mildawati, Ratna
Innovative: Journal Of Social Science Research Vol. 1 No. 1 (2021): Innovative: Journal of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

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Abstract

Diabetes mellitus is a chronic disease that requires long-term treatment. In diabetes mellitus patients, physical exercise is often neglected, one of which is due to lack of knowledge. This research aims to determine the effect of educational videos about diabetic foot exercises on implementing foot exercises in type 2 diabetes mellitus patients at the Chania Care Center, Kediri Regency. The research design used a quasi-experimental design with a one-group pretest-posttest approach. The population in this study was 30 respondents. A total sample of 30 respondents was taken using the total sampling technique. The instrument used the observation sheet. Nominal data scale. The analysis test uses the Mc Nemar test. In this research, before giving the educational video, almost all of them did not do leg exercises, namely 23 respondents (76.7%), after giving the educational video, almost all of them did foot exercises, 26 respondents (86.7%). The results of the Mc Nemar Test analysis showed an effect of providing educational videos about diabetic foot exercises on implementing foot exercises in type 2 diabetes mellitus patients at the Chania care center in Kediri district (p-value = 0.001 < α=0.05). A person's knowledge can increase after being given education or health education. Educational methods with videos about diabetes foot exercises can increase DM patients' knowledge of doing foot exercises to improve peripheral blood circulation to the feet.
Edukasi Menjaga Pola Hidup Sehat Tentang Penyakit Diabetes Melitus dan Hipertensi Pada Era COVID-19 Di Car Free Day Kota Kediri Prasetyawan, Fendy; Karingga, Devangga Darma Karingga; Saristiana, Yuneka; Mildawati, Ratna; Astutik, Widhi
Interaksi : Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 1 (2024): Interaksi - Juni
Publisher : PT. Faaslib Serambi Media

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Abstract

Implementasi edukasi pola hidup sehat terkait diabetes melitus dan hipertensi selama pandemi COVID-19 melibatkan persiapan, pelaksanaan, dukungan, dan kolaborasi. Materi edukasi komprehensif disampaikan melalui sesi tatap muka dan virtual serta media sosial. Evaluasi menunjukkan peningkatan signifikan dalam pengetahuan, sikap, dan perilaku kesehatan peserta. Program ini mendorong adopsi pola makan seimbang, aktivitas fisik rutin, dan manajemen stres efektif. Kolaborasi dengan organisasi kesehatan dan komunitas lokal memperluas jangkauan program. Meskipun dihadapi tantangan seperti pembatasan sosial dan akses terbatas, solusi adaptif telah diterapkan untuk memastikan kelangsungan program. Evaluasi kontinu dan adaptasi strategi mendukung upaya program dalam mencapai perubahan positif dalam kesehatan masyarakat.
ANALISIS KRONOFARMAKOLOGI PENGGUNAAN PARACETAMOL PADA PASIEN COVID-19 DI RSUD DR. SOEDOMO TRENGGALEK Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Mildawati, Ratna; Oktadiana, Isma; Arifin, Chandra; Rofiq, Abd; Febriana, Laela; Besan, Emma jayanti; Fadel, Muhammad Nurul
Journal of Social Science and Multidisciplinary Analysis Vol. 1 No. 1 (2024): Journal of Social Science and Multidisciplinary Analysis (Jossama), February 20
Publisher : Noble Cendekia Indonesia

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Abstract

The global COVID-19 pandemic has presented complex challenges to global health. Dr. Soedomo Regional General Hospital in Trenggalek has actively engaged in managing COVID-19 patients. This study aims to analyze the chronopharmacology of paracetamol usage in COVID-19 patients at the hospital, focusing on the body's biological response to the drug at various time points within the 24-hour cycle. In the treatment of COVID-19, the use of paracetamol has become a primary strategy for addressing symptoms such as fever. However, it is crucial to understand how the timing of paracetamol administration can influence the body's response to the treatment. A chronopharmacological study involving 100 patients analyzed body temperature before and after therapy at three different times: 08:00 AM, 04:00 PM, and 10:00 PM. The results revealed a significant decrease in body temperature after therapy, particularly at 04:00 PM. These findings support the concept of "the right time, the right dose" in clinical practice. Analysis of the body's circadian rhythm emphasizes the need to consider the timing of drug administration to achieve optimal outcomes. Despite the limited sample size, this research provides a foundation for the development of more precise practical guidelines for administering paracetamol to COVID-19 patients.
UPAYA PENINGKATAN PENGETAHUAN TENTANG PENGGUNAAN OBAT YANG BENAR MELALUI EDUKASI DAGUSIBU OBAT PADA KADER POSYANDU Mildawati, Ratna; Prasetyo Nugroho , Bandhi; Hamida Oktavia , Laura
Jurnal LENTERA Vol. 5 No. 1 (2025): Jurnal LENTERA
Publisher : Stikes Yarsi Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/lentera.v5i1.430

Abstract

Each medication has beneficial effects on the body but also carries harmful side effects. Currently, Indonesian society is becoming increasingly accustomed to the use of various types of medications for purposes such as treating illnesses, managing conditions, or as supplements to support daily activities. Therefore, knowledge about medications is essential for the community to ensure their proper and effective use. The DAGUSIBU program was initiated to enhance public understanding of the wise use and management of medications. Its goal is to increase public awareness and comprehension of proper and accurate medication management and monitoring. The methods employed include lectures using educational leaflets and PowerPoint presentations, discussions, and Q&A sessions. The educational outcomes show a significant improvement: prior to the educational intervention, only 27.3% of respondents had good knowledge. Following the intervention, this figure increased to 90%, representing a 60% improvement. This demonstrates that the activity successfully enhanced public understanding of rational medication use. Posyandu cadres can actively contribute to delivering DAGUSIBU-related education to the community.
THE POTENTIAL ACTIVITY OF ASIATICOSIDE FROM AKAR MANIS (Glycyrrhiza glabra) AS HYPOLIPEMIC Prasetyawan, Fendy; Saristiana, Yuneka; Salmasfattah, Novyananda; Mildawati, Ratna; Mayasari, Shinta
PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS Vol. 3 No. 4 (2024): OCTOBER
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55047/comorbid.v3i4.1608

Abstract

Asiaticoside, a bioactive compound derived from Glycyrrhiza glabra (licorice root), has garnered attention for its potential as a hypolipemic agent. This study explores the lipid-lowering effects of asiaticoside, focusing on its mechanism of action and pharmacological properties. In silico analysis showed a high activation probability (pa=0.934) for asiaticoside, indicating its strong potential to interact with targets involved in lipid metabolism, such as PPAR-α, and reduce blood lipid levels. Additionally, its low inhibition probability (pi=0.003) suggests minimal risk for non-specific biological interference, making it a promising candidate for therapeutic use with a favorable safety profile. Asiaticoside’s antioxidant and anti-inflammatory properties further enhance its potential for cardiovascular protection by reducing oxidative stress, a key factor in atherosclerosis. While preliminary in silico results are promising, further in vitro and in vivo studies are required to confirm its efficacy, safety, and pharmacokinetics. Overall, asiaticoside represents a promising natural agent for managing hyperlipidemia and related metabolic disorders, offering an alternative to conventional synthetic therapies.
Uji Aktivitas Antipembekuan Darah dan Docking dari Daun Kaki Unta (Waltheria indica L.) Awilda, Pertiwi; Bawaihi, Bawaihi; Jiddan, Muhammad Jayyid; Mildawati, Ratna; Hadi, Samsul
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 2 (2025): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i2.31402

Abstract

Di Indonesia, prevalensi penyakit jantung koroner (PJK) adalah 1,5% di semua kelompok umur, sehingga masih menjadi masalah serius. Jika berbicara tentang penyakit kardiovaskular, PJK berada di urutan teratas. Tujuan dari penelitian ini adalah uji aktivitas W. indica berkaitan dengan kemampuan sebagai antikoagulan. Darah tikus digunakan untuk teknik pengujian in vitro, sedangkan waktu pendarahan tikus diukur untuk pengujian in vivo, dengan menggunakan perangkat lunak PLANT dalam docking, penelitian insilico digunakan untuk mengidentifikasi senyawa dari W. indica yang mungkin memiliki sifat antikoagulan, Discovery Studio kemudian digunakan untuk mengidentifikasi residu yang terlibat dalam interaksi dan skor doking digunakan dalam analisis data. Hasil uji in vitro untuk ekstrak etanol menunjukkan adanya koagulasi pada menit ke-30, fraksi n-heksana pada menit ke-10, fraksi etil asetat dan n-butanol pada menit ke-60, dan pada uji in vivo pendarahan hingga 349 ± 23 detik untuk dosis 100 mg/kg BB, 425 ± 27 detik untuk dosis 200 mg/kg BB, dan 546 ± 34 detik untuk dosis 300 mg/kg BB, hal ini lebih baik dari pada kontrol, dan dengan docking mengungkapkan bahwa senyawa yang berpotensi dalam  pengujian ini adalah quercetin. Kesimpulannnya  W. indica  berpotensi sebagai antipembekuan  darah
Analisis Cost-Benefit Terapi Simvastatin dengan Atorvastatin pada Pasien Dislipidemia di Apotek 71 Kota Kediri dengan Pendekatan Human Capital Method Prasetyawan, Fendy; Saristiana, Yuneka; Mildawati, Ratna; Fadel, Muhammad Nurul; Besan, Emma Jayanti; Astutik, Widhi; Arifin, Chandra; Rofiq, Abd; Rhomah, Eka Hayati
Business and Economic Publication Vol. 3 No. 2 (2025): Business and Economic Publication
Publisher : Fakultas Ekonomi Universitas KH. A. Wahab Hasbullah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32764/bep.v3i2.1571

Abstract

This study aims to analyze the cost-benefit of simvastatin therapy compared to atorvastatin in dyslipidemia patients at Apotek 71 Kediri City using the Human Capital Method. Using a cross-sectional study design, this study analyzed 60 patients (30 simvastatin users, 30 atorvastatin users). Productivity loss data was collected through a patient self-report questionnaire and valued monetarily using the assumption of a uniform daily wage. Results showed that direct costs of simvastatin were lower (IDR 75,000/month) than atorvastatin (IDR 210,000/month), but lost productivity in the simvastatin group was higher (IDR 384,000) than atorvastatin (IDR 180,000). The Net Benefit value of simvastatin therapy was -Rp 39,000 with a Benefit Cost Ratio (BCR) of 0.91, while atorvastatin produced a Net Benefit of +Rp 210,000 with a BCR of 1.54. The difference in Net Benefit was statistically significant based on an independent t-test (p=0.002). Thus, atorvastatin is more economically efficient than simvastatin because it provides higher productivity benefits despite higher direct costs.
Interactive Discussion Related to the Preparation of Pharmacy Professional Work Practice at the Health Center and Health Office Saristiana, Yuneka; Prasetyawan, Fendy; Mildawati, Ratna; Marhenta, Yogi Bhakti; Kadir, Mujtahid Bin Abd; Arifin, Chandra; Rofiq, Abd; Astutik, Widhi; Rohmah, Eka Hayati
Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) Vol. 1 No. 1 (2025): Maret
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/mjpmm.v1.i1.3

Abstract

The Professional Pharmacy Practice Experience (PKPA) at Community Health Centers and Health Offices plays a crucial role in developing the professional competence of pharmacy students before they enter the actual workforce. To facilitate this preparation, an interactive discussion activity has been conducted as a means of training and collective reflection among students, supervising lecturers, and resource persons from the Health Office and community health centers. This discussion aims to enhance students' understanding of the roles and responsibilities of pharmacists within primary healthcare facilities (FKTP), while also identifying the challenges and solutions involved in the implementation of PKPA. The execution of the discussion demonstrated a high level of enthusiasm among students in exploring both the technical and non-technical aspects of the pharmacy profession, including the integration of clinical and managerial roles. The evaluation of the questionnaire reveals that over 85% of participants believe this activity significantly aids in preparing them to confront the PKPA with greater confidence. Group discussions highlight the significance of interpersonal communication skills, professional ethics, and teamwork collaboration as essential factors for the success of practice. A representative from the Health Department assessed that this activity is effective in aligning the perspectives between educational institutions and practical venues, thereby fostering ongoing synergy.
Community Empowerment Through Increasing Knowledge About the Truth of the Drug NZT-48 as a Neurotrophic in Increasing Brain Potential: Pengabdian Masyarakat Melalui Peningkatan Pengetahuan Tentang Kebenaran Obat NZT-48 sebagai Neurotropik dalam Meningkatkan Potensi Otak Saristiana, Yuneka; Prasetyawan, Fendy; Mildawati, Ratna; Arifin, Chandra; Rofiq, Abd; Astutik, Widhi
Journal of Social and Community Service Vol. 3 No. 3 (2024): November 2024
Publisher : Faculty of Engineering University of Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jestmc.v3i3.196

Abstract

The community service aimed to bridge the gap between scientific knowledge and public perception regarding nootropics. Through a comprehensive approach involving meticulous planning, community engagement, educational activities, expert consultations, feedback collection, and evaluation, the program sought to increase awareness and understanding of cognitive enhancement substances among participants. Real-life case studies and guest lectures by renowned experts enriched the learning experience, addressing scientific, ethical, and social perspectives. The proactive involvement of community leaders and an effective awareness campaign ensured high participation and relevance. It underscored the importance of a multidisciplinary approach in addressing complex topics and highlighted the value of engaging communities in meaningful discussions about health and well-being. The program not only educated the community about the realities and myths surrounding NZT-48 and other nootropics but also promoted critical thinking and informed decision- making. By empowering the community with accurate information and fostering a culture of informed skepticism, the program contributed to the betterment of community health and well-being, setting a precedent for future public health education initiatives.
Co-Authors Anis Akhwan Dhafin Ardianto, Nanda Astutik, Widhi Awilda, Pertiwi Bawaihi Bawaihi Besan, Emma Jayanti Candra Arifin, Candra Chandra Arifin Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Hakim, Adiyansyah Lukman Hamida Oktavia , Laura Jiddan, Muhammad Jayyid Kadir, Mujtahid Bin Abd Karingga, Devangga Darma Khumaeni, Eko Hidayaturrohman Kristjono, Ary Lailaturohmah, Lailaturohmah M. Wahyu Ariawan Marhenta, Yogi Bhakti Muhammad Nurul Fadel Ning Arti Wulandari, Ning Arti Oktadiana, Isma Prasetyo Nugroho , Bandhi Prasetyo Nugroho, Bandhi Putri, Elsa Mahardika Raharjo, Susilo Margining Rhomah, Eka Hayati Rofiq, Abd Rohmah, Eka Hayati Romadhon, Wimar Anugrah Salmasfattah, Novyananda Samsul Hadi Shinta Mayasari Titik Juwariyah Winarni, Jajuk Yuneka Saristiana