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Studi Kualitatif : Analisis Faktor-Faktor yang Mempengaruhi Pengobatan Pasien TB di Puskesmas Sentosa Baru Veronika Bertua Simanjuntak; Erida Novriani; Razoki Razoki
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4751

Abstract

Tuberculosis (TB) is a global health problem, with Indonesia having the second highest number of cases in the world. Although morbidity and mortality rates from TB are still high, the disease is curable with proper treatment. The success of TB therapy can be influenced by various factors such as patient compliance, knowledge about TB, patient motivation, family support, education level, socioeconomic conditions, access to health facilities, the role of health workers, drug side effects, and comorbidities. This study aims to analyze the factors that influence the successful treatment of TB patients at Puskesmas Sentosa Baru. This study used a qualitative method with a cross-sectional descriptive approach, this study involved 15 TB patients who were interviewed in depth until the data reached the point of saturation, as well as observation and documentation. From the results of the research conducted, it was found that the factors that influence the success of patient treatment at Sentosa Baru Health Center are the level of patient compliance, level of knowledge, and patient motivation. Patients who have a better understanding of the disease tend to be more disciplined in undergoing therapy, while family support is a strong driver in improving patient adherence to treatment. Therefore, increased education, monitoring of adherence, and more intensive social support are needed so that patients can complete treatment optimally and break the chain of TB transmission.
Uji Efektivitas Ekstrak Etanol Daun Jarak Pagar (Jatropha curcas L.) dalam Menurunkan Kadar Gula Darah pada Mencit (Mus musculus) yang Diinduksi Glukosa Monohidrat Nadira Aisyah Lubis; Erida Novriani; Finna Piska
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 2 (2026): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i2.6414

Abstract

Diabetes mellitus is a chronic metabolic disorder with an increasing global prevalence, emphasizing the need for safe, effective, and affordable alternative therapies. This study aimed to evaluate the antidiabetic potential of ethanol extract from physic nut leaves (Jatropha curcas L.) in reducing blood glucose levels in glucose monohydrate–induced mice (Mus musculus). An experimental design was applied using 25 male mice divided into five groups: a negative control group receiving Na-CMC, a positive control group treated with glibenclamide (5 mg), and three treatment groups administered ethanol extract doses of 21.8 mg/25 g body weight, 43.7 mg/25 g body weight, and 65.6 mg/25 g body weight. Blood glucose levels were measured to assess the hypoglycemic effect of each treatment. The results showed that the ethanol extract of Jatropha curcas leaves significantly reduced blood glucose levels compared to the control groups (p < 0.05). The highest dose, 65.6 mg/25 g body weight, demonstrated the greatest reduction in blood glucose levels. These findings suggest that ethanol extract of physic nut leaves has promising potential as a natural antidiabetic agent and may serve as an alternative therapeutic option for diabetes management.
Identifikasi Drug Related Problems Potensial Kategori Interaksi Obat pada Pasien Hipertensi di RSU Royal Prima Medan Erida Novriani; Sintia Juniartha Purba; Vera Estefania Kaban
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 2 (2026): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i2.6448

Abstract

Hypertension is a disease whose prevalence continues to increase from year to year, and the success of its therapy is largely determined by the appropriateness of drug selection and use. Treatment failure may occur when the chosen and administered medications do not match the patient’s condition, particularly when accompanied by drug-related problems (DRPs). Poorly controlled hypertension can lead to complications such as heart disease, kidney failure, and stroke. This study aims to identify DRPs among hypertensive patients with or without comorbidities, assessed in terms of the use of medications without indications, indications without medications, excessive dosage, insufficient dosage, and drug interactions. This research is a descriptive, non-experimental study employing a cross-sectional design with retrospective data collection among hypertensive patients with or without comorbidities at RSU Royal Prima Medan during the January–June 2025 period. The sample was selected using purposive sampling based on the inclusion criteria, resulting in a total of 135 patients.
Uji Aktivitas Ekstrak Bunga Mawar (Rosa Damascena) sebagai Antibakteri terhadap Propionibactrium Acnes Penyebab Jerawat Cindy Olivia Panggabean; Erida Novriani; Razoki Lubis
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.7642

Abstract

Jerawat vulgaris adalah kondisi yang menyebabkan peradangan pada kulit. Salah satu bakteri penyebab jerawat adalah Propionibacterium acnes, yang memiliki protein yang mampu mendegradasi jaringan kulit dan memicu peradangan. Ekstrak bunga mawar (Rosa damascena) mengandung metabolit sekunder yang berfungsi sebagai agen antibakteri, seperti tanin, geraniol, nerol, sitronelol, dan flavonoid. Tujuan penelitian ini adalah untuk menentukan aktivitas penghambatan antibakteri ekstrak bunga mawar (Rosa damascena) terhadap pertumbuhan Propionibacterium acnes, salah satu bakteri penyebab jerawat. Metode yang digunakan dalam penelitian ini melibatkan pembuatan ekstrak bunga mawar (Rosa damascena) dalam beberapa variasi konsentrasi, yaitu 30%, 20%, dan 10%, dan pengujian terhadap pertumbuhan Propionibacterium acnes. Hasil penelitian menunjukkan bahwa zona penghambatan yang dihasilkan pada konsentrasi 20% dan 30% dikategorikan sangat kuat, sedangkan zona penghambatan pada konsentrasi 10% dikategorikan kuat. Efektivitas antibakteri ekstrak bunga mawar (Rosa damascena) ini diyakini disebabkan oleh adanya senyawa metabolit sekunder seperti flavonoid, tanin, dan saponin. Kesimpulannya, ekstrak bunga mawar (Rosa damascena) menunjukkan aktivitas antibakteri, khususnya dalam menghambat pertumbuhan bakteri penyebab jerawat, yaitu Propionibacterium acnes, dengan efek penghambatan maksimal yang diamati pada konsentrasi 30%.