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All Journal Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Buletin Konseling Inovatif
Rivera, Alice Tonido
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Social Sciences Other

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Profile of flavonoid bioactive compounds in moringa leaves (Moringa oleifera) as phytoestrogens Primiani, Cicilia Novi; Pujiati , Pujiati; Prayitno, Trio Ageng; Setiawan, Mohammad Arfi; Rivera, Alice Tonido
Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Vol. 10 No. 01 (2025): Edubiotik : Jurnal Pendidikan, Biologi dan Terapan
Publisher : Biology Education Department, Universitas Insan Budi Utomo, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33503/ebio.v10i01.1446

Abstract

Moringa oleifera with the local name moringa, is widely used for health, as a medicinal plant. However, its potential as a natural estrogenic is not yet known. The study aimed to analyse and identify flavonoid compounds of moringa leaves and to analyse the estrogenic potential of moringa leaves on 17β-estradiol levels of female rats. Research with an experimental approach includes: 1) Metabolite profiling of moringa leaf extract using 95% methanol solvent, with stages including extract dilution, protein precipitation, and extract purification with SPE. Extract purification using solid phase extraction using C18 Sep-Pak; 2) Induction to 4-5 months female Wistar rats, 240 - 280 g, 24 heads, grouped into 3 treatment groups, namely control (P0), administration of 17β-estradiol (P1) and administration of 1.5 ml moringa leaf feeling water (P2), treatment for 25 days. Data collection techniques include LCMS chromatogram data and data on 17β-estradiol levels taken from rat tail veins. Descriptive data analysis techniques include: 1) Chromatogram result data of flavonoid compound groups and 2) Data on 17β-estradiol levels using ELIZA on day 26. The conclusion of the results showed that the flavonoid compounds of moringa leaves were 29 compounds, including isoflavone and coumestan groups. Giving moringa leaf juice can increase 17β-estradiol levels in rats by 524.346 mg/dl.
Hallo Kons: Web-Based Guidance and Counseling Services to Improve University Students’ Well-being Christiana, Ratih; Wardani, Silvia Yula; Suharni, Suharni; Mahmudi, Ibnu; Aji, Afara Dinan Sa'id Restu; Rahmawati, Shinta; Dwi, Puspita; Rivera, Alice Tonido
Buletin Konseling Inovatif Vol. 5, No. 2
Publisher : citeus

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Abstract

This study aims to develop 'Hallo Kons' which is an innovation of website-based guidance and counseling services to improve the well-being of students at Universitas PGRI Madiun (UNIPMA), which include four areas of guidance and counseling services, namely: personal, social, learning and career. The method in this study is research and development (R&D). The subjects of the study were website experts, UNIPMA counselors and students of UNIPMA. The data analysis used was qualitative and quantitative, with data collection techniques using assessment sheets filled out by 4 experts: consisting of 2 website experts and 2 experts in the field of guidance and counseling, which showed the results of expert validation tests with an average value of 62.5 (good category), guidance and counseling experts with an average value of 61.5 (good category), then for the practical test carried out by 2 counselors with assessment indicators: (1) understanding, (2) Implementation, (3) Ease, then for small group trials on student user of Hallo Kons, a sig. value was obtained. (2-tailed) of 0.000 and it can be concluded that Hallo Kons is effective in improving the psychological well-being of students at Universitas PGRI Madiun (UNIPMA).
Co-Authors Aji, Afara Dinan Sa'id Restu Cicilia Novi Primiani Dwi, Puspita Ibnu Mahmudi, Ibnu Mohammad Arfi Setiawan Pujiati , Pujiati Rahmawati, Shinta Ratih Christiana, Ratih Silvia Yula Wardani, Silvia Yula Suharni Suharni Trio Ageng Prayitno, Trio Ageng