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All Journal Sciences of Pharmacy PANDAWA : Jurnal Pengabdian kepada Masyarakat
Guanse, Yovi
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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EDUKASI LIPID PADA SISWA SEKOLAH DASAR: PENINGKATAN PEMAHAMAN MELALUI PENGABDIAN MASYARAKAT Handoyo, Theodorus Rexa; Reihana, Elza; Guanse, Yovi; Purwati, Purwati; Hasbullah, Zahra Rahmawati; Opur, Hamka George Marly Hairil; Hanim, Abra Uzri; Supit, Tesalonica Maria
PANDAWA : Jurnal Pengabdian kepada Masyarakat Vol 4, No 1 (2025): PANDAWA: JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : UNIVERSITAS 17 AGUSTUS 1945 JAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/pandawa.v4i1.8481

Abstract

Lipid atau lemak adalah zat gizi makro yang memiliki peran penting dalam tubuh manusia, tidak hanya sebagai sumber energi yang tinggi tetapi juga dalam melarutkan vitamin dan menyediakan asam lemak esensial. Namun, pemahaman anak-anak, khususnya siswa sekolah dasar, mengenai fungsi lipid masih terbatas dan seringkali menggeneralisasi semua lemak sebagai berbahaya tanpa membedakan antara lemak sehat dan jahat. Penelitian ini dilakukan di SDN Sunter Jaya 03, Jakarta Utara, dengan sasaran 60 siswa kelas 4 berusia 9–10 tahun, bertujuan meningkatkan pengetahuan mereka tentang lipid melalui penyuluhan edukatif yang melibatkan presentasi multimedia, diskusi interaktif, dan kuis partisipatif. Hasil uji pre-test dan post-test menunjukkan peningkatan signifikan pada kategori nilai tinggi (90–100) dari 53,45% menjadi 75,86%, sementara kategori menengah menurun dari 37,93% menjadi 12,07%. Partisipasi aktif selama sesi edukasi melebihi 75%, menunjukkan metode interaktif sangat efektif dalam meningkatkan pemahaman siswa tentang lipid. Temuan ini mendukung pentingnya edukasi dini dalam membentuk pola makan seimbang serta mencegah obesitas pada anak.
Effect of Tween 80 and Span 80 Surfactants Systems on the Malus domestica Emulsions for Anti-Cutibacterium acnes Handoyo, Theodorus Rexa; Resmi, Juniar Kalpika; Hutabarat, Rahmi; Guanse, Yovi
Sciences of Pharmacy Volume 5 Issue 1
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0501526

Abstract

Red apple (Malus domestica) extract, rich in hydrophobic quercetin, was formulated into oil-in-water (O/W) emulsion using a 22 factorial design to evaluate Tween 80 (8-10 g) and Span 80 (2-4 g) concentrations, targeting pH (4.5-6.0), transmittance (90-100%), and viscosity (10-2000 cPs). Design-Expert® 13 analysis identified formulations F1, FA, and FAB within acceptable physical property ranges, with all red apple emulsions exhibiting O/W type, skin-compatible pH (5.20-5.48), high transmittance, and suitable viscosity. Freeze-thaw cycling (3 cycles, -15/25°C) and centrifugation showed physical stability with non-significant changes for F1 (p > 0.05). The agar well diffusion assay was performed on F1 (n = 3), which exhibited optimal physical parameters and met stability criteria, revealing Cutibacterium acnes inhibition zones up to 22.7 ± 0.577 mm. Thus, F1 emerges as a promising nanoemulsion candidate demonstrating antibacterial activity against acne-causing bacteria.
Effects of Xanthan, CMC-Na, and Avicel RC-591 on Sucralfate Suspension Characteristics and Physical Stability Hutabarat, Rahmi; Guanse, Yovi; Resmi, Juniar Kalpika; Handoyo, Theodorus Rexa
Sciences of Pharmacy Volume 5 Issue 3 (2026)
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0503650

Abstract

Sucralfate is a medicine for peptic ulcers that is practically insoluble in water and might to be developed into a suspension. The choice of suspending agents is essential for formula development. This study aimed to determine the physical characteristics and physical stability of xanthan gum, CMC-Na, and Avicel RC-591 in a sucralfate suspension by conducting a characterization and stability study and analyzing the formulations. Suspensions were prepared with 0.3% w/v xanthan gum (XG), 1% w/v CMC-Na (SCMC), and 1% w/v Avicel RC-591 (ARC) and then evaluated for physical appearance, pH, density, viscosity, sedimentation, and redispersibility in a six-month stability study conducted under various storage conditions. The pH results ranged between 5.113 ± 0.001 and 4.622 ± 0.033 (p > 0.05). The density of the SCMC formula (1.1459 ± 0.0003) is greater than the density of the ARC formula (1.1396 ± 0.0002) and XG (1.1162 ± 0.0002), but statistically, the three formulas are not significantly different (p > 0.05). The viscosity of XG is greater than SCMC and ARC. The formulas indicated that XG had greater sedimentation than SCMC and ARC (p > 0.05). The redispersibility of all formulations is ARC > SCMC > XG. In conclusion, ARC and SCMC exhibit acceptable suspension characteristics and robust physical stability. Conversely, formulations utilizing XG fail to meet the required quality standards for sucralfate suspensions regarding redispersibility.
Co-Authors Elza Reihana Hanim, Abra Uzri Hasbullah, Zahra Rahmawati Opur, Hamka George Marly Hairil Purwati Purwati Rahmi Hutabarat Resmi, Juniar Kalpika Supit, Tesalonica Maria Theodorus Rexa Handoyo