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Daya Hambat Hand Sanitizer di Masyarakat: Apakah Efektif ? Taslim, Tuty; Salim, Reny; Dewi, Irene Puspa
Jurnal Riset Kefarmasian Indonesia Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i2.250

Abstract

Hand sanitizer is one of the Household Health Supplies (PKRT) which is one of the human needs when the Covid-19 pandemic appears throughout the world. Panic at the beginning of the spread of Covid-19 has caused many people to buy and store hand sanitizers, resulting in shortages everywhere. WHO announced the composition for the manufacture of hand sanitizers. And the government allows making hand sanitizers without going through actual regulations so that hand sanitizers appear in several dosage forms such as sprays and gels suitable for antiseptic purposes. The inhibition of hand sanitizers against microbes needs to be tested considering its function as a microbial exterminator on human hands, so this research needs to be done to determine the effectiveness of hand sanitizers circulating in the community. The microbes used are Staphylococcus aureus and Escherichia coli. The sampling technique was carried out by purposive sampling and its effectiveness by using the disc diffusion method. The results obtained are that all hand sanitizers sampled have a diameter of inhibition as a strong antiseptic 10%, 50% sufficient and 40% weak.
Optimization of Ethanol-Water Solvent System for Total Flavonoid Extraction from Okara Reny Salim; Tuty Taslim; Irene Puspa Dewi; Verawaty
Indonesian Journal of Chemical Science Vol. 15 No. 2 (2026): Indonesian Journal of Chemical Science
Publisher : Prodi Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ijcs.v15i2.46170

Abstract

Okara, an agro-industrial by product of soybean processing, is a potential source of flavonoids, particularly isoflavones. However, its large scale production often exceeds current utilization, resulting in its underexploitation. This study investigates the effect of ethanol-water solvent ratios on the total flavonoid content of dried okara powder and includes physicochemical characterization of the raw material. Extraction was carried out by maceration using ethanol-water mixtures (v/v) of 1:2 and 2:1. The total flavonoid content was 676.88 ± 15.66 µg/g dry weight for the 1:2 solvent system and 137.87 ± 0.53 µg/g dry weight for the 2:1 solvent system. These findings demonstrate that increasing the proportion of water in the solvent system enhances the extraction efficiency of flavonoids from okara.