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All Journal Jurnal Keperawatan Jiwa (JKJ): Persatuan Perawat Nasional Indonesia Indonesian Journal of Pharmaceutical Science and Technology JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Katalisator JURNAL KESEHATAN PERINTIS Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Jurnal Riset Kefarmasian Indonesia JAFP (Jurnal Akademi Farmasi Prayoga) Lamahu: Jurnal Pengabdian Masyarakat Terintegrasi Dharma Pengabdian Perguruan Tinggi (DEPATI) Jurnal Pengabdian kepada Masyarakat (ABDIKEMAS) Jurnal Katalisator Jurnal Kesehatan Farmasi Indonesian Journal of Chemical Science
Salim, Reny
Akademi Farmasi Prayoga
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PHYTOCHEMICALS & ANTIOXIDANT ACTIVITY OF ANDALIMAN SEEDS AND FLESH Salim, Reny
Indonesian Journal of Chemical Science Vol. 13 No. 1 (2024)
Publisher : Prodi Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Andaliman fruit is one kind of spice that has antioxidant benefits. Secondary antioxidants are needed by the human body to combat internal and external free radicals. Effort can be made to eliminate these free radicals by eating foods that have active compounds with adequate antioxidant activity. The study aims to identify the group of secondary metabolite compounds and the antioxidant activity of fruit flesh and seeds. The extraction method used is maceration using a 70% ethanol-acidified solvent. The phytochemical screening method is a color reaction. The method of antioxidant activity is DPPH. Result of the phytochemical screening of simplisia and extract of fruit (seeds and flesh) show the presence of alkaloids, flavonoids, terpenoids, and tannins. The results of the phytochemical screening of seed simplisia revealed the presence of alkaloids, terpenoids, and tannins. The antioxidant activity of seed and flesh extracts falls into the strong category with IC50 values of (56,80 and 52,32) ppm. It has been suggested that the maceration method using the acidified solvent affects the antioxidant activity of seeds and flesh of the andaliman fruit.
Aktivitas Antihiperkolesterol Infusa Daun Mangga Harum Manis (Mangifera indica L.) Dewi, Irene Puspa; Elvi Zai, Fransiska; Salim, Reny; Taslim, Tuty; Verawaty, Verawaty
JURNAL KESEHATAN PERINTIS Vol. 12 No. 2 (2025): Jurnal Kesehatan Perintis
Publisher : LPPM UNIVERSITAS PERINTIS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33653/f64mwk34

Abstract

Daun mangga mengandung senyawa flavonoid, saponin, glikosida, tannin, dan fenolik yang berpotensi dimanfaatkan sebagai agen antikolesterol. Penyiapan daun mangga dalam bentuk infusa dapat dengan mudah dilakukan masyarakat. Penelitian ini ditujukan untuk mengkaji aktivitas antihiperkolesterol infusa daun mangga harum manis. Mencit yang dijadikan model pada pengujian ini diinduksi dengan kuning telur puyuh selama 14 hari hingga mencit mengalami hiperkolesterol. Mencit kemudian diberikan perlakuan sesuai dengan kelompok perlakuan masing-masing dengan memberikan infusa daun mangga haru manus konsentrasi 10%, 20% dan 30% selama 14 hari dan dilakukan pengukuran kadar kolesterol darah mencit dengan alat pengujian kolesterol digital. Kadar kolesterol mencit yang diberikan infusa daun mangga harum manis 10%, 20%, dan 30% berturut-turut turun sebesar 19,81%, 29,70% dan 29,48%. Secara statistik peningkatan konsentrasi infusa daun mangga harum manis tidak meningkatkan aktivitas penurunan kadar kolesterol darah mencit secara signifikan. Aktivitas penurunan kadar kolesterol darah mencit kelompok infusa daun mangga 10%, 20% dan 30% tidak berbeda secara signifikan dengan kelompok pembanding yang diberikan Simvastatin. Infusa daun mangga harum manis memberikan aktivitas antikolesterol pada mencit yang diinduksi diet hiperkolesterol.
Co-Authors Eliyarti Eliyarti Elvi Zai, Fransiska Fita Selonni Fita Selonni Intan Sri Rahayu Irene Puspa Dewi Irene Puspa Dewi Irene Puspa Dewi Irene Puspa Dewi, Irene Puspa Manurung, Tumpal Selonni, Fita Suryani Suryani Talitha Rhinarda Tumpal Manurung Tuty Taslim Tuty Taslim Tuty Taslim Verawaty Verawaty Verawaty Verawaty Verawaty, Verawaty Winda Maiza