Claim Missing Document
Check
Articles

Found 22 Documents
Search

Aktivitas Antihiperkolesterol Infusa Daun Mangga Harum Manis (Mangifera indica L.) Dewi, Irene Puspa; Elvi Zai, Fransiska; Salim, Reny; Taslim, Tuty; Verawaty, Verawaty
JURNAL KESEHATAN PERINTIS Vol. 12 No. 2 (2025): Jurnal Kesehatan Perintis
Publisher : LPPM UNIVERSITAS PERINTIS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33653/f64mwk34

Abstract

Daun mangga mengandung senyawa flavonoid, saponin, glikosida, tannin, dan fenolik yang berpotensi dimanfaatkan sebagai agen antikolesterol. Penyiapan daun mangga dalam bentuk infusa dapat dengan mudah dilakukan masyarakat. Penelitian ini ditujukan untuk mengkaji aktivitas antihiperkolesterol infusa daun mangga harum manis. Mencit yang dijadikan model pada pengujian ini diinduksi dengan kuning telur puyuh selama 14 hari hingga mencit mengalami hiperkolesterol. Mencit kemudian diberikan perlakuan sesuai dengan kelompok perlakuan masing-masing dengan memberikan infusa daun mangga haru manus konsentrasi 10%, 20% dan 30% selama 14 hari dan dilakukan pengukuran kadar kolesterol darah mencit dengan alat pengujian kolesterol digital. Kadar kolesterol mencit yang diberikan infusa daun mangga harum manis 10%, 20%, dan 30% berturut-turut turun sebesar 19,81%, 29,70% dan 29,48%. Secara statistik peningkatan konsentrasi infusa daun mangga harum manis tidak meningkatkan aktivitas penurunan kadar kolesterol darah mencit secara signifikan. Aktivitas penurunan kadar kolesterol darah mencit kelompok infusa daun mangga 10%, 20% dan 30% tidak berbeda secara signifikan dengan kelompok pembanding yang diberikan Simvastatin. Infusa daun mangga harum manis memberikan aktivitas antikolesterol pada mencit yang diinduksi diet hiperkolesterol.
Daya Hambat Hand Sanitizer di Masyarakat: Apakah Efektif ? Taslim, Tuty; Salim, Reny; Dewi, Irene Puspa
Jurnal Riset Kefarmasian Indonesia Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i2.250

Abstract

Hand sanitizer is one of the Household Health Supplies (PKRT) which is one of the human needs when the Covid-19 pandemic appears throughout the world. Panic at the beginning of the spread of Covid-19 has caused many people to buy and store hand sanitizers, resulting in shortages everywhere. WHO announced the composition for the manufacture of hand sanitizers. And the government allows making hand sanitizers without going through actual regulations so that hand sanitizers appear in several dosage forms such as sprays and gels suitable for antiseptic purposes. The inhibition of hand sanitizers against microbes needs to be tested considering its function as a microbial exterminator on human hands, so this research needs to be done to determine the effectiveness of hand sanitizers circulating in the community. The microbes used are Staphylococcus aureus and Escherichia coli. The sampling technique was carried out by purposive sampling and its effectiveness by using the disc diffusion method. The results obtained are that all hand sanitizers sampled have a diameter of inhibition as a strong antiseptic 10%, 50% sufficient and 40% weak.