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All Journal JURNAL FARMASIMED (JFM) Jurnal Farmasi Indonesia
Eva Nurinda
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Medicine & Pharmacology

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FORMULASI DAN UJI IRITASI SEDIAAN MASKER PEEL OFF GEL KOMBINASI EKSTRAK ETANOL BUNGA TELANG (Clitoria ternatea L.) DAN KUNYIT PUTIH (Curcuma zedoaria) Putri, Safira Amalia; Annisa Fatmawati; Eva Nurinda; Didik Yuni Prasetya
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 17 No 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i2.328

Abstract

Butterfly pea flower (Clitoria ternatea L.) and white turmeric (Curcuma zedoaria) have antioxidant activity and can be combined to make a peel off gel mask. To ensure the quality and safety of the peel off gel mask, it is necessary to evaluate its physical properties and test for irritation. The manufacturing process involves extracting butterfly pea flower and white turmeric using a maceration method using 70% ethanol solvent. The resulting extract was tested for phytochemistry to identify alkaloids, saponins, flavonoids and tannins. The preparation was formulated with variations in extract concentrations: FI (1:3), FII (2:2) and FIII (3:1). Evaluation of physical properties includes organoleptic tests, pH, spreadability, homogeneity, stickiness, drying time and viscosity. Irritation tests were carried out on New Zealand rabbits. The result indicated that the peel off gel mask with various extract concentrations met most of the physical property evaluation requirements even though the pH test did not meet the standards. The EEBT and EEKP combination peel off gel mask did not cause irritation in New Zealand rabbits during 72 hours of observation.
The Role of Medication Adherence Companions on the Pharmacotherapy Outcomes of Hypertensive Patients at Bambanglipuro Community Health Center Aprianto A, Diki; Eva Nurinda; Ari Susiana Wulandari; Ade Puspitasari; Ifa Aris Suminingtyas
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/7r11af50

Abstract

Hypertension is a prevalent chronic condition in primary health care, particularly among geriatric patients requiring long-term therapy. Despite the availability of antihypertensive medications, achieving target blood pressure remains challenging and is often associated with poor medication adherence. Medication Adherence Companions (PMO) may improve adherence and enhance therapeutic outcomes. This study aimed to analyze the role of PMO in the pharmacotherapy outcomes of hypertensive patients at the Bambanglipuro Community Health Center. This analytic observational study with a cross-sectional design involved 101 geriatric patients diagnosed with hypertension. Data were collected using structured questionnaires covering patient characteristics, presence of PMO, medication adherence, and blood pressure control status. Data were analyzed descriptively and using multivariate logistic regression with a significance level of p < 0.05. The results showed that 64.4% of patients had a PMO, and 54.5% demonstrated high adherence. Patients with high adherence were more likely to achieve controlled blood pressure. Multivariate analysis revealed that the presence of PMO significantly increased the likelihood of controlled blood pressure (AOR = 2.77; 95% CI: 1.29–5.95; p = 0.009). Combination therapy was also significantly associated with blood pressure control (AOR = 2.25; p = 0.047). These findings suggest that Medication Adherence Companions can support successful hypertension pharmacotherapy among geriatric patients in primary health care settings.
Co-Authors Ade Puspitasari Annisa Fatmawati Aprianto A, Diki Ari Susiana Wulandari Didik Yuni Prasetya Ifa Aris Suminingtyas Putri, Safira Amalia