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All Journal INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Media Farmasi Indonesia Miracle Get Journal
Ade Puspitasari
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Formulation and SPF Evaluation of a Lip Oil Serum Combining Ethanol Extract of Butterfly Pea Flower and Lavender Oil Nurus Shobah Salsabila; Annisa Fatmawati; Sundari Desi Nuryanti; Emelda; Ade Puspitasari; Latifa Amalia
Media Farmasi Indonesia Vol. 20 No. 2 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i2.341

Abstract

Exposure to ultraviolet (UV) radiation due to ozone layer depletion increases the risk of skin damage, particularly on the lips, which are more vulnerable due to their lack of melanin and sebaceous glands. This study aimed to formulate and evaluate the Sun Protection Factor (SPF) of a lip oil serum containing ethanol extract of butterfly pea flower (Clitoria ternatea L.) and lavender oil (Lavandula angustifolia). The formulation was prepared in a single base with four variants: a control (F0) and three active concentrations (F1, F2, F3). Physical evaluations included organoleptic tests, homogeneity, pH, spreadability, adhesion, and viscosity. The SPF values were assessed in vitro using UV-Vis spectrophotometry. All formulations demonstrated acceptable physical stability with pH values between 6.7–7.33, spreadability ranging from 6.85–7.34 cm, adhesion from 3.51–5.07 seconds, and viscosity from 777.6–839 cPS. The SPF increased proportionally with lavender oil concentration (F1 = 3.70, F2 = 4.09, F3 = 4.25), showing a strong positive correlation (r = 0.969). These findings suggest that the combined use of butterfly pea extract and lavender oil may offer mild UV protection and desirable physical properties, making it a promising candidate for natural, herbal-based lip care products.
Overview of Return Times for Inpatient Medical Records at Andalas University Hospital Rahmadhani; Oktamianiza; Ade Puspitasari
Miracle Journal Get Press Vol 1 No 2 (2024): May, 2024
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/mgj.v1i2.30

Abstract

One supporting element for medical record processing is the prompt return of files belonging to patients who have concluded their inpatient healthcare services. The established standard for the return of these medical records is within a maximum of 48 hours. This research aims to ascertain the timeframe the return of hospitalized patient records at Andalas University Hospital in Padang. The investigation employed a quantitative approach utilizing descriptive methods. The research took place in the storage room at Andalas University Hospital, Padang. The investigation took place starting from May to September 2023. The population of this study was 302 files with a sample of 75 medical record files with data collection time from 20 to 25 September 2023. The research applied the Simple Random Sampling technique. Data gathering involved observation and data processing techniques including editing, coding, processing, and cleaning. The analysis focused on univariate analysis. Results from Andalas University Hospital revealed that 31 files (41.3%) returned accurate medical records, while 44 files (58.7%) were found to have incorrect medical records returned. This indicates that many medical record files were returned after the stipulated timeframe of >48 hours. As a conclusion from the study, it's imperative for the head of the medical records room to assess and supervise the return process of inpatient medical record files. By doing so, this issue can be mitigated and delays in Submitting the medical records of a hospitalized patient anew files can be minimized.
Tren Global Penelitian Toll-like receptor 4 pada Penyakit Kardiovaskular: Analisis Bibliometrik 2017-2025 Danang Amukti; Daru Estiningsih; Tetie Herlina; Nurul Kusumawardani; Ade Puspitasari; Latifa Amalia; Ifa Aris Suminingtyas; Eva Nurinda; Sundari Desi Nuryanti; Ari Susiana Wulandari; Ria Indah Pratami
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 9 No. 1 (2025)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v9i1.5989

Abstract

Toll-like receptor 4 (TLR4) memiliki peran penting dalam patogenesis penyakit kardiovaskular (PKV) melalui mediasi respons inflamasi. Meskipun peran molekul ini semakin dikenal, belum ada kajian bibliometrik komprehensif yang mengulas tren global publikasi terkait TLR4 dalam konteks PKV secara sistematis. Tujuan penelitian ini bertujuan untuk menganalisis dinamika publikasi ilmiah global tentang TLR4 pada PKV dalam kurun waktu 2017–2025 menggunakan pendekatan bibliometrik. Data dikumpulkan dari database Scopus dengan kata kunci “Toll-like receptor 4” dan “cardiovascular”, difilter berdasarkan judul, abstrak, dan kata kunci, serta dibatasi pada dokumen berbahasa Inggris. Sebanyak 1.939 dokumen dianalisis menggunakan perangkat lunak Bibliometrix (R) dan VOSviewer untuk mengevaluasi tren publikasi, produktivitas penulis, kontribusi negara dan institusi, pemetaan kata kunci, dan artikel yang paling berpengaruh. Tiongkok mendominasi jumlah publikasi (592 dokumen), sementara Amerika Serikat mencatat pengaruh ilmiah tertinggi melalui kolaborasi internasional dan jumlah sitasi. Penulis paling produktif adalah Li Y dan Wang Y, sedangkan institusi teratas adalah Mashhad University dan Capital Medical University. Peta kata kunci menunjukkan empat klaster utama: inflamasi-imunitas, stres oksidatif-apoptosis, metabolisme, dan model hewan. Artikel paling disitasi berasal dari jurnal bereputasi tinggi seperti Signal Transduction and Targeted Therapy dan Nature Reviews Rheumatology. TLR4 merupakan target utama dalam penelitian multidisipliner dan translasi pada penyakit kardiovaskular. Hasil studi ini dapat menjadi acuan penting untuk perumusan strategi riset lanjutan dan kolaborasi global yang lebih terarah.
Analisis Adverse Drug Reaction (ADR) Pengobatan Diabetes Melitus Nefropati Terhadap Clinical Outcome di RSUD Panembahan Senopati Bantul Nurhasanah Nurhasanah; Eva Nurinda; Sofyan Indrayana; Diki Aprianto A; Adhi Gunawan; Ari Susiana Wulandari; Muhimmatul Khoiriyah; Wahyu Yuliana Solikhah; Sundari Desi; Ade Puspitasari
INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Vol. 9 No. 2 (2025)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/inpharnmed.v9i2.6630

Abstract

Diabetes Melitus (DM) adalah suatu penyakit kronis atau gangguan metabolisme kronis multifaktorial, ditandai dengan tingginya kadar gula darah terkait gangguan metabolisme karbohidrat, lipid, protein akibat malfungsi insulin. Komplikasi yang ditimbulkan dari Diabetes Melitus akan menyebabkan pasien sebanyak 20% hingga 40% mengalami nefropati diabetik atau gagal ginjal stadium akhir. Dalam mengatasi konsekuensi akibat nefropati, maka obat merupakan pilihan yang diambil. Dari obat yang diberikan mempunyai efek obat berbeda setiap pasien, karena setiap obat memiliki mekanisme kerja dan tempat kerja yang berbeda yang akhirnya menyebabkan perubahan respon obat dan munculnya ADR. Tujuan penelitian adalah mengetahui pengaruh Adverse Drug Reaction (ADR) pada diabetes melitus nefropati terhadap outcome klinik di RSUD Panembahan Senopati Bantul. Desain penelitian berupa penelitian non eksperimental dengan menggunakan teknik retrospektif yaitu pengamatan kasus dari rekam medis pasien. Metode pengambilan sampel ini menggunakan purposive sampling. Hasil penelitian juga menunjukan bahwa tidak ada hubungan antara ADR dengan clinical outcome berdasarkan nilai GDS pada pasien DM nefropati di RSUD Panembahan Senopati Bantul di hari pertama dan ketiga yang di tunjukan oleh nilai p value 0,621 dan 0,728 (p>0,05). Mayoritas responden mengalami ADR dari pengobatan yaitu sebanyak 37 responden (58,7%), sedangkan 26 responden (41,3%) lainnya tidak mengalami ADR dari pengobatan
Co-Authors Adhi Gunawan Annisa Fatmawati Ari Susiana Wulandari Danang Amukti Daru Estiningsih Diki Aprianto A Emelda Eva Nurinda Eva Nurinda Ifa Aris Suminingtyas Indrayana, Sofyan Kusumawardani, Nurul Latifa Amalia Muhimmatul Khoiriyah Nurhasanah Nurhasanah Nurus Shobah Salsabila Nuryanti, Sundari Desi Oktamianiza Rahmadhani Ria Indah Pratami Sundari Desi Tetie Herlina Wahyu Yuliana Solikhah