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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) JURNAL FARMASIMED (JFM) REMIK : Riset dan E-Jurnal Manajemen Informatika Komputer Community Development Journal: Jurnal Pengabdian Masyarakat Indian Journal of Forensic Medicine & Toxicology SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Journal of Agropharmacy
Kusumaningrum , Yunita Dyah
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Public Health Social Sciences

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Journal : JURNAL FARMASIMED (JFM)

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Evaluation of Pioglitazone Vildagliptin Combination on Lipid Profiles for Outpatients with Type II Diabetes Mellitus Kusumaningrum, Yunita Dyah; Firandi, Adelia; Hasmono, Didik; Aryani, Dhita; Wardhani, Firdha Aprillia
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2645

Abstract

Pioglitazone and vildagliptin combination is one of the recommended alternatives as antidiabetic therapy to achieve the therapeutic target. This combination with complementary mechanisms of action can improve lipid profiles. This study aims to evaluate lipid profile achievement for outpatients with Type II DM on administering pioglitazone/vildagliptin combination therapy. Methods of the study were an observational prospective study in outpatients with Type II DM who use pioglitazone/vildagliptin combination at RS. Bhayangkara Surabaya during November 2021 – April 2022. Patients were included if aged between 18-80 y.o, used this combination ? 3 months before the study, HbA1C >7%, and were voluntarily involved by signing the informed consent. Laboratory examination of HbA1c, HDL-C, and triglycerides was done initially when patients were voluntarily involved as baseline data and after 3 months as post-data. The final sample in this study consisted of 25 patients who met the inclusion and exclusion criteria. The results of the study show mean value of HDL-C significantly increases from baseline to endpoint (p < 0.05). At the end of 3 months, the lipid profile of HDL-C and triglyceride increases by 30% and 4%, respectively, in patients who achieve the target compared to baseline conditions. The combination therapy of pioglitazone and vildagliptin improved lipid profile control in patients with type 2 diabetes mellitus after 3 months of treatment.
Knowledge and Attitudes of Indigenous Papuan Communities Toward HIV/AIDS in Nabire District Rachmawati, Ema; Kusumaningrum, Yunita Dyah; Machlaurin, Afifah; Firandi, Adelia; Damayanti, Putri Elsa
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/2cfpmp04

Abstract

Human Immunodeficiency Virus (HIV) is a virus that attacks white blood cells and gradually weakens the immune system. Without appropriate treatment, HIV infection can progress to Acquired Immunodeficiency Syndrome (AIDS), a late stage marked by severe immune impairment. Papua is one of the provinces with the highest HIV/AIDS prevalence in Indonesia which indicating the importance of understanding community knowledge and attitudes as key elements in prevention and control efforts. This study aimed to describe the level of knowledge and attitudes toward HIV/AIDS among Indigenous Papuan communities in Nabire District. This study employed a descriptive cross-sectional design. Data were collected using a questionnaire that had been tested for validity and reliability, consisting of 23 knowledge items and 11 attitude items. A total of 300 respondents who met the inclusion criteria were included in the analysis. The findings showed that respondents’ knowledge was categorized as high (28%), moderate (32%), and low (39.67%). With regard to attitudes toward HIV/AIDS, 13% of respondents demonstrated good attitudes, 42.67% had moderate attitudes, and 43.67% showed poor attitudes. It can be concluded that the average level of knowledge among indigenous Papuan communities remains low, accompanied by less favorable attitudes toward HIV/AIDS. These findings indicate the need to strengthen more intensive, targeted, and socio-culturally appropriate educational programs to improve knowledge and promote more positive attitudes toward HIV/AIDS particularly in Nabire District.
Co-Authors Adelia Firandi Afandi, Khoirunnisa Aryani, Dhita Aryani, Dhita Evi Atmoko, Rizky Damayanti, Putri Elsa Dewi Wara Shinta Diana Holidah Didik Hasmono Ema Rachmawati Firandi, Adelia Ika Norcahyanti Kartiko, Erik Yohan M. Habibullah Arief Machlaurin, Afifah Mareta Rindang Andarsari Ramadhani, Nuril Izzati Farihatur Rosy Nurlita, Hapsari RR. Ella Evrita Hestiandari Sinta Rachmawati Susilo, Dwi Hari Syafika, Devina Sarah Wardhani, Firdha Wardhani, Firdha Aprillia