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All Journal Argipa (Arsip gizi dan Pangan) Journal SAGO Gizi dan Kesehatan
Ndopo, Fernando Diaz
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Asam amino rantai cabang terhadap status gizi, dan perubahan metabolik pada penyakit hati: Sebuah tinjauan sistematis Wityadarda, Carissa; Immanuella, Ester Hanantika; Ndopo, Fernando Diaz; Ester, Teresa; Siregar, Sarah Damayanti; Berliana, Yuli
Jurnal SAGO Gizi dan Kesehatan Vol 6, No 3 (2025): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v6i3.2407

Abstract

Background: Liver diseases such as non-alcoholic fatty liver disease (NAFLD) and cirrhosis are influenced by factors like viral infections, alcohol, immune dysfunction, genetic predisposition, and metabolic factors. Branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—are vital for protein metabolism and liver function. The role of BCAAs in liver disease and metabolic changes requires further study.Objectives:  To evaluate the role of BCAAs in nutritional status and metabolic changes in liver disease through a systematic review.Methods: A systematic review was conducted following the PRISMA protocol. Literature was searched on Google Scholar for publications from 2019 to 2024. Studies were selected based on inclusion and exclusion criteria. Descriptive analysis summarized the findings, and statistical tests evaluated the relationship between BCAA consumption or supplementation and liver disease progression.Results: Eight studies met the inclusion criteria. High BCAA consumption was associated with an increased risk of NAFLD (OR = 1,32, p < 0,001). In contrast, BCAA supplementation improved MELD and CP scores in cirrhotic patients. Elevated BCAA levels were also linked to a higher risk of type 2 diabetes (OR = 1,60, 95% CI = 1,14-2,23, p = 0,006).Conclusions: BCAA supplementation may help slow cirrhosis progression and improve sarcopenia and liver function. However, its use should be tailored to avoid adverse effects. More research is needed to explore long-term effects on liver disease.
Pengaruh webinar series “SIPEDE“ strategi intervensi gizi penyakit degeneratif terhadap pemahaman peserta: Studi pre-test dan post-test WEBINAR SERIES “SIPEDE“ STRATEGI INTERVENSI GIZI PENYAKIT DEGENERATIF TERHADAP PEMAHAMAN PESERTA: STUDI PRE-TEST DAN POST- TEST Wityadarda, Carissa; Saputra, Mochamad Novian; Nurfadhilah, Andisa Alfani; Tirza Damar Ratri; Aditiyan, Nasya Salsabila; Ndopo, Fernando Diaz; Nurfadhilla, Nabilla Bilqi; Rahardianti, Syifha Nur Sallyima; Hardjanti, Maura; Parulian, Adi Anggoro; Victoria, Bernadette
ARGIPA (Arsip Gizi dan Pangan) Vol 10 No 2 (2025)
Publisher : UHAMKA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/argipa.v10i2.19327

Abstract

Lifestyle decisions, human behavior, and knowledge of dietary selections contribute to degenerative diseases. Indonesia has difficulty with nutrition literacy; this nutrition education needs to be more thorough. One way to do this is to use internet media, like webinars, to teach in a non-linear way. The objective of this study was to assess the impact of the “SIPEDE” webinar on participants’ comprehension of nutritional intervention techniques in the management of degenerative disease. A pre-experimental survey of 729 participants was administered prior to and after the intervention. We used pre-test and post-test questionnaires to collect data. These surveys asked about knowledge of degenerative disease, risk factors, and nutritional intervention options. A paired t-test was used to look at scores before and after the intervention. The results demonstrated a knowledge score enhancement of roughly 23,32% in the post-test, rising from 65,71 in the pre-test to 82,01 in the post-test (p<0,05). In other words, the webinar helped people learn more about nutrition and degenerative diseases, which makes it a good way to teach people about nutrition that can be used by many people in the community.
Co-Authors Adi Anggoro Parulian Aditiyan, Nasya Salsabila Berliana, Yuli Ester, Teresa Hardjanti, Maura Immanuella, Ester Hanantika Nurfadhilah, Andisa Alfani Nurfadhilla, Nabilla Bilqi Rahardianti, Syifha Nur Sallyima Saputra, Mochamad Novian Siregar, Sarah Damayanti Tirza Damar Ratri Victoria, Bernadette Wityadarda, Carissa