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All Journal Argipa (Arsip gizi dan Pangan) Journal SAGO Gizi dan Kesehatan
Immanuella, Ester Hanantika
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Telaah pustaka kebiasaan makan di Benua Asia termasuk Indonesia: Implikasi terhadap status gizi, epigenetik dan kesehatan Wityadarda, Carissa; Amanda, Nadia; Immanuella, Ester Hanantika; Nurfadhilah, Andisa Alfani; Anita, Meliana Tri; Rahardianti, Syifha Nur Sallyima; Febrianti, Tamara Denisa; Siregar, Sarah Damayanti; Kinasih, Teresa Ester Sekar; Morin, Abigael Lauce; Dewi, M Falah Putra; Berliana , Yuli
ARGIPA (Arsip Gizi dan Pangan) Vol 10 No 1 (2025)
Publisher : UHAMKA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/argipa.v10i1.18295

Abstract

Dietary habits in Asia, including Indonesia, are shaped by culture, tradition, and the ongoing influence of modernization. Modernization has led to a shift from traditional diets toward the consumption of processed foods high in calories, fats, and sugars, increasing the risk of degenerative diseases such as obesity, diabetes, and cardiovascular disorders. These dietary changes also affect nutritional status and can influence gene expression through epigenetic mechanisms and genetic variation among individuals. This  tudy aims to examine dietary patterns in Asian populations and their implications for nutritional status and health through the lens of epigenetics, nutrigenomics, and nutrigenetics. This study employed a narrative literature review using a qualitative-descriptive approach. Scientific articles were gathered through Google Scholar in October 2024 using a combination of English and Indonesian keywords such as “eating habits in Asia”, “Asian dietary pattern”, “Indonesian food culture”, “epigenetics and nutrition”, “nutrigenomics in Asia”, and “nutrigenetics population”. The process involved four systematic steps: article identification, selection based on inclusion and exclusion criteria, data extraction, and thematic analysis based on geographic regions. The results show that culture and modernization significantly influence dietary patterns in Asia. Additionally, bioactive compounds found in traditional Asian foods have the potential to modulate gene expression, and genetic variations among populations may lead to different responses to the same dietary intake. This review highlights the importance of culturally tailored nutrition education and the need for population-based nutrigenetic research.
Asam amino rantai cabang terhadap status gizi, dan perubahan metabolik pada penyakit hati: Sebuah tinjauan sistematis Wityadarda, Carissa; Immanuella, Ester Hanantika; Ndopo, Fernando Diaz; Ester, Teresa; Siregar, Sarah Damayanti; Berliana, Yuli
Jurnal SAGO Gizi dan Kesehatan Vol 6, No 3 (2025): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v6i3.2407

Abstract

Background: Liver diseases such as non-alcoholic fatty liver disease (NAFLD) and cirrhosis are influenced by factors like viral infections, alcohol, immune dysfunction, genetic predisposition, and metabolic factors. Branched-chain amino acids (BCAAs)—leucine, isoleucine, and valine—are vital for protein metabolism and liver function. The role of BCAAs in liver disease and metabolic changes requires further study.Objectives:  To evaluate the role of BCAAs in nutritional status and metabolic changes in liver disease through a systematic review.Methods: A systematic review was conducted following the PRISMA protocol. Literature was searched on Google Scholar for publications from 2019 to 2024. Studies were selected based on inclusion and exclusion criteria. Descriptive analysis summarized the findings, and statistical tests evaluated the relationship between BCAA consumption or supplementation and liver disease progression.Results: Eight studies met the inclusion criteria. High BCAA consumption was associated with an increased risk of NAFLD (OR = 1,32, p < 0,001). In contrast, BCAA supplementation improved MELD and CP scores in cirrhotic patients. Elevated BCAA levels were also linked to a higher risk of type 2 diabetes (OR = 1,60, 95% CI = 1,14-2,23, p = 0,006).Conclusions: BCAA supplementation may help slow cirrhosis progression and improve sarcopenia and liver function. However, its use should be tailored to avoid adverse effects. More research is needed to explore long-term effects on liver disease.
Co-Authors Amanda, Nadia Anita, Meliana Tri Berliana , Yuli Berliana, Yuli Dewi, M Falah Putra Ester, Teresa Febrianti, Tamara Denisa Hardjanti, Maura Kinasih, Teresa Ester Sekar Morin, Abigael Lauce Ndopo, Fernando Diaz Nurfadhilah, Andisa Alfani Nurfadhilla, Nabilla Bilqi Rahardianti, Syifha Nur Sallyima Siregar, Sarah Damayanti Victoria, Bernadette Wityadarda, Carissa Yura Witsqa Firmansyah