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POTENSI SENYAWA BIOAKTIF DARI EUCHEUMA COTTONII TERHADAP GEN NS5 DAN ENVELOPE (E) VIRUS DENGUE SERTA TARGET ACHE DAN OBP PADA AEDES AEGYPTI: TINJAUAN MINI Vincentia Ade Rizky; Maria Selviana Joni; Umi Latifah; Ni’mah Hidayatul Laili; Eka Nurul H.P.S; Avinda Sari Kanthi Rahayu; Rachmat Saleh; Nasrullah Tamrin; Awaluddin; Adipura Atmadja Egok; Tri Astuti Sugiyatmi
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 4 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Desember 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i4.2015

Dengue fever remains a major global health concern, especially in tropical regions, due to increasing insecticide resistance and the absence of specific antiviral treatments. Marine-derived natural products, such as those from Eucheuma cottonii, offer promising alternatives. This mini-review aims to evaluate the potential of E. cottonii bioactive compounds targeting molecular markers of Aedes aegypti mosquitoes and the Dengue virus (DENV). A review of 30 relevant national and international articles published between 2015 and 2025 was conducted, focusing on the larvicidal and antiviral activities of E. cottonii. E. cottonii contains flavonoids, alkaloids, terpenoids, and sulfated polysaccharides. These compounds inhibit AChE and OBP enzymes in mosquito larvae and target the NS5 and Envelope (E) proteins of DENV. The antiviral effects are also enhanced by its antioxidant and immunomodulatory activities. Eucheuma cottonii has a significant potential as a multifunctional natural resource for sustainable strategies in dengue control.

Penerapan Perilaku Hidup Bersih dan Sehat pada Karyawan Embung Persemaian di Kota Tarakan Maria Selviana Joni; Vincentia Ade Rizky; Umi Latifah; Tri Astuti Sugiyatmi
Jurnal Kabar Masyarakat Vol. 4 No. 2 (2026): Mei: JURNAL KABAR MASYARAKAT
Publisher : Institut Teknologi dan Bisnis Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54066/jkb.v4i2.3804

Clean and Healthy Living Behavior (PHBS) is a promotive and preventive effort that aims to improve the degree of public health through behavior change. Nursery reservoir employees have a high risk of exposure to the work environment in the form of dirty water, biological waste, and pathogenic microorganisms. This community service activity was carried out to increase the knowledge and practice of PHBS among employees of the nursery reservoir in Juata Tarakan based on national PHBS indicators. The implementation method includes counseling, demonstration, and evaluation using pre-test and post-test. The results showed a significant increase in employee knowledge, with an average pre-test score of 58.7 increasing to 78.3 in the post-test. The statistical test resulted in a value of p = 0.000 (p < 0.05), which confirms the effectiveness of PHBS educational interventions in improving workers' health knowledge and behavior. These findings provide practical implications that counseling-based education and demonstrations can be an effective strategy in encouraging the implementation of PHBS in risky work environments. Thus, this activity is expected to be able to support the creation of a healthier work environment, increase productivity, and become a model for community-based occupational health interventions.

Potensi Larvasida Tanaman Endemik Kalimantan terhadap Aedes aegypti: Tinjauan Evidensi Ilmiah dan Prioritas Kandidat Riset Vincentia Ade Rizky; Maria Selviana Joni; Umi Latifah; Tri Astuti Sugiyatmi
JURNAL RISET RUMPUN MATEMATIKA DAN ILMU PENGETAHUAN ALAM Vol. 5 No. 1 (2026): April : JURRIMIPA: Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrimipa.v5i1.9131

Dengue remains a major vector-borne disease worldwide, and the increasing resistance of Aedes aegypti to synthetic insecticides has encouraged the exploration of environmentally friendly botanical larvicides. This study aimed to systematically evaluate scientific evidence regarding the larvicidal potential of endemic Kalimantan plants against Aedes aegypti and to identify priority candidates for future research. A systematic literature review was conducted following the PRISMA 2020 guidelines. Literature searches were performed across Scopus, PubMed, ScienceDirect, SpringerLink, Web of Science, MDPI, Wiley Online Library, Garuda, SINTA, and Google Scholar for studies published between January 2016 and January 2026. A total of 925 records were identified, and after duplicate removal, screening, and eligibility assessment, 88 studies were included in the final synthesis. The results showed that botanical larvicides rich in alkaloids, flavonoids, terpenoids, phenolics, limonoids, and sulfur compounds demonstrated significant larvicidal activity against Aedes aegypti. However, no direct larvicidal studies were identified for endemic Kalimantan species, including Fibraurea tinctoria, Arcangelisia flava, Dacrydium beccarii, Agathis borneensis, and Scorodocarpus borneensis. These findings highlight substantial evidence gaps and indicate that Kalimantan biodiversity represents a promising source of novel larvicidal agents for sustainable dengue vector control.

Pendampingan Pengelolaan Sampah Berbasis Komunitas Menuju Ecohealthy Campus dan Desa Wisata Sehat Tri Astuti Sugiyatmi; Rachmat Saleh; Nasrullah Tamrin; Eka Nurul Hidayah Puspa Seruni; Awaluddin Awaluddin; Adipura Atmadja Egok; Vincentia Ade Rizky; Avinda Sari Kanthi Rahayu; Maria Selviana Joni; Umi Latifah; Ni'mah Hidayatul Laili
Jurnal Medika: Medika Vol. 5 No. 1 (2026)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/m5mtm120

Permasalahan pengelolaan sampah yang belum optimal masih menjadi isu utama di kawasan pesisir Kota Tarakan, khususnya di Kelurahan Pantai Amal yang berfungsi sebagai kawasan wisata sekaligus lokasi Kampus Universitas Borneo Tarakan. Wilayah ini juga merupakan sentra budidaya rumput laut, di mana penggunaan botol plastik sebagai pelampung berkontribusi terhadap timbulan sampah pesisir yang berdampak pada kesehatan lingkungan. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan, kesadaran, dan komitmen sosial petugas kebersihan Universitas Borneo Tarakan serta anggota Kelompok Swadaya Masyarakat (KSM) Tempat Pengolahan Sampah (TPS) 3R (Reduce, Reuse, Recycle) Amal Jaya dalam pengelolaan sampah berbasis prinsip 3R dan kesehatan lingkungan. Metode yang digunakan adalah pendampingan komunitas melalui penyuluhan interaktif, diskusi, pemberian media edukasi, serta demonstrasi pembuatan komposter metode Takakura. Evaluasi dilakukan secara deskriptif menggunakan pre-test dan post-test serta observasi partisipasi peserta. Kegiatan dilaksanakan dalam dua tahap pada 30 September dan 7 Oktober 2025. Hasil kegiatan menunjukkan tingkat pengetahuan peserta berada pada kategori tinggi, disertai peningkatan pemahaman dan keterlibatan aktif. Kegiatan ini menghasilkan komitmen kolektif untuk melanjutkan pendampingan KSM TPS 3R guna mendukung terwujudnya Ecohealthy Campus dan Desa Wisata Sehat Pantai Amal.

PEMANFAATAN EKSTRAK GETAH DAN KULIT BUAH MUDA TARAP (ARTOCARPUS ODORATISSIMUS) SEBAGAI LARVASIDA NABATI Umi Latifah; Vincentia Ade Rizkya; Maria Selviana Joni; Nasrullah Tamrin; Tri Astuti Sugiyatmi
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 7 (2026): SINERGI : Jurnal Riset Ilmiah, Juli 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i7.2786

Dengue hemorrhagic fever (DHF) remains a major public health problem in Indonesia, highlighting the need for effective and environmentally friendly vector control strategies. Botanical larvicides derived from local plants offer a promising alternative to synthetic insecticides. This study evaluated the larvicidal activity of young tarap (Artocarpus odoratissimus) fruit sap and peel extracts against mosquito larvae. Six treatment groups were used: negative control, positive control, peel filtrate, sap filtrate, peel powder, and peel sediment, with 25 larvae per group and three replicates. Larval mortality was recorded after 24 and 48 hours. The positive control caused 100% mortality at both observation times. Among the botanical treatments, peel filtrate showed 95% mortality at 24 hours and 100% at 48 hours, while peel powder and peel sediment achieved 99–100% mortality after 48 hours. Sap filtrate produced lower but substantial mortality (89% at 48 hours). These findings indicate that young tarap fruit peel exhibits strong larvicidal activity and has considerable potential for development as an eco-friendly botanical larvicide for dengue vector control.

PENYUSUNAN REKOMENDASI KESEHATAN LINGKUNGAN WILAYAH PESISIR BERBASIS DATA SEKUNDER Maria Selviana Joni; Vincentia Ade Rizky; Umi Latifah
MAJU : Indonesian Journal of Community Empowerment Vol. 3 No. 1 (2026): MAJU : Indonesian Journal of Community Empowerment, January 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/maju.v3i1.2276

Coastal areas are vulnerable to environmental health problems, particularly those related to sanitation, clean water access, and domestic waste management. Poor environmental conditions contribute to the increased risk of environment-based diseases such as diarrhea and skin infections. This community service activity aimed to develop environmental health recommendations for coastal areas based on secondary data analysis. The method used was descriptive analysis of secondary data obtained from health profiles, statistical reports, and regional development planning documents. The analysis showed gaps between existing environmental health conditions and ideal health standards. Based on these findings, environmental health intervention recommendations focusing on disease prevention, health education, and strengthening primary health services were formulated. These recommendations are expected to support stakeholders in planning sustainable environmental health programs in coastal areas.

Penerapan Perilaku Hidup Bersih dan Sehat pada Karyawan Embung Persemaian di Kota Tarakan Maria Selviana Joni; Vincentia Ade Rizky; Umi Latifah; Tri Astuti Sugiyatmi
Jurnal Kabar Masyarakat Vol. 4 No. 2 (2026): Mei: JURNAL KABAR MASYARAKAT
Publisher : Institut Teknologi dan Bisnis Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54066/jkb.v4i2.3804

Clean and Healthy Living Behavior (PHBS) is a promotive and preventive effort that aims to improve the degree of public health through behavior change. Nursery reservoir employees have a high risk of exposure to the work environment in the form of dirty water, biological waste, and pathogenic microorganisms. This community service activity was carried out to increase the knowledge and practice of PHBS among employees of the nursery reservoir in Juata Tarakan based on national PHBS indicators. The implementation method includes counseling, demonstration, and evaluation using pre-test and post-test. The results showed a significant increase in employee knowledge, with an average pre-test score of 58.7 increasing to 78.3 in the post-test. The statistical test resulted in a value of p = 0.000 (p < 0.05), which confirms the effectiveness of PHBS educational interventions in improving workers' health knowledge and behavior. These findings provide practical implications that counseling-based education and demonstrations can be an effective strategy in encouraging the implementation of PHBS in risky work environments. Thus, this activity is expected to be able to support the creation of a healthier work environment, increase productivity, and become a model for community-based occupational health interventions.

Analisis Epidemiologi Spasio-Temporal Infeksi Dengue Tahun 2016–2025 di Tarakan Tri Astuti Sugiyatmi; Vincentia Ade Rizky; Maria Selviana Joni; Rachmat Saleh; Umi Latifah
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 3 (2026): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i3.6688

Dengue Hemorrhagic Fever (DHF) remains a serious public health problem in Tarakan City, Indonesia, with case numbers fluctuating annually. This study aimed to analyze trends in DHF incidence and map the spatial distribution of cases and the Larval-Free Index (LFI) in Tarakan City from 2016 to 2025. A descriptive observational study with a retrospective approach was conducted using secondary data obtained from the Tarakan City Health Department. The variables analyzed included the number of DHF cases, incidence rate (IR), case fatality rate (CFR), endemicity status of subdistricts, and the 2025 LFI. Descriptive analysis and Geographic Information System (GIS)-based spatial mapping were performed. The results showed fluctuating trends in DHF incidence throughout the study period. In 2025, 90 cases were reported, with an IR of 35.2 per 100,000 population and a CFR of 1.11%. Most cases occurred in endemic areas. Spatial analysis revealed an uneven distribution of cases, with some urban villages showing lower LFI values but higher dengue incidence. These findings indicate that GIS-based mapping can support the identification of priority areas for surveillance, vector control, and sustainable larval source reduction programs.

Efektivitas E-Modul Berbasis Video Terhadap Peningkatan Keterampilan Klinis Mahasiswa Pada Pembelajaran Skill Laboratory Ni'mah Hidayatul Laili; Avinda Sari Kanthi Rahayu; Eka Nurul HPS; Vincentia Ade Rizky; Maria Selviana Joni; Umi Latifah; Rachmat Saleh; Awaluddin Awaluddin; Nasrullah Tamrin; Adipura Atmadja Egok; Tri Astuti Sugiyatmi
Science: Indonesian Journal of Science Vol. 2 No. 5 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/sciencejurnalkesehatanmasyarakatdanteknologiterapan.v2i5.403

Pembelajaran keterampilan klinis pada mahasiswa kedokteran merupakan komponen penting dalam membentuk kompetensi profesional yang terstandar. Proses pembelajaran di skill laboratory sering menghadapi kendala, seperti keterbatasan waktu praktik, variasi kemampuan mahasiswa, serta kurangnya media pembelajaran yang dapat diakses secara fleksibel. . Pembelajaran keterampilan klinis di skill laboratory membutuhkan media yang efektif untuk menunjang peningkatan kemampuan mahasiswa. Penelitian ini bertujuan untuk menganalisis efektivitas e-modul berbasis video terhadap peningkatan keterampilan klinis mahasiswa. Metode penelitian menggunakan desain kuasi-eksperimen dengan pendekatan one group pre-test dan post-test design melalui kuesioner yang diberikan sebelum dan sesudah penggunaan e-modul pada mahasiswa. Data dianalisis secara deskriptif dengan membandingkan hasil sebelum dan setelah intervensi. Hasil menunjukkan adanya peningkatan pemahaman materi, keterampilan prosedural, serta kepercayaan diri mahasiswa dalam melakukan tindakan klinis. Sebagian besar responden juga memberikan penilaian positif terhadap kemudahan penggunaan, kejelasan materi, dan fleksibilitas akses e-modul berbasis video. Kesimpulan penelitian ini adalah e-modul berbasis video efektif dalam meningkatkan keterampilan klinis mahasiswa dan layak digunakan sebagai media pembelajaran pendukung pada kegiatan skill laboratory.

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