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All Journal Journal of Noncommunicable Diseases Prevention and Control Jurnal Medika: Medika Jurnal Sains, Teknologi dan Kesehatan Science: Indonesian Journal of Science
Adipura Atmadja Egok
Universitas Borneo Tarakan
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Engineering Health Professions Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health

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POTENSI SENYAWA BIOAKTIF DARI EUCHEUMA COTTONII TERHADAP GEN NS5 DAN ENVELOPE (E) VIRUS DENGUE SERTA TARGET ACHE DAN OBP PADA AEDES AEGYPTI: TINJAUAN MINI Vincentia Ade Rizky; Maria Selviana Joni; Umi Latifah; Ni’mah Hidayatul Laili; Eka Nurul H.P.S; Avinda Sari Kanthi Rahayu; Rachmat Saleh; Nasrullah Tamrin; Awaluddin; Adipura Atmadja Egok; Tri Astuti Sugiyatmi
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 4 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Desember 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i4.2015

Abstract

Dengue fever remains a major global health concern, especially in tropical regions, due to increasing insecticide resistance and the absence of specific antiviral treatments. Marine-derived natural products, such as those from Eucheuma cottonii, offer promising alternatives. This mini-review aims to evaluate the potential of E. cottonii bioactive compounds targeting molecular markers of Aedes aegypti mosquitoes and the Dengue virus (DENV). A review of 30 relevant national and international articles published between 2015 and 2025 was conducted, focusing on the larvicidal and antiviral activities of E. cottonii. E. cottonii contains flavonoids, alkaloids, terpenoids, and sulfated polysaccharides. These compounds inhibit AChE and OBP enzymes in mosquito larvae and target the NS5 and Envelope (E) proteins of DENV. The antiviral effects are also enhanced by its antioxidant and immunomodulatory activities. Eucheuma cottonii has a significant potential as a multifunctional natural resource for sustainable strategies in dengue control.
Pendampingan Pengelolaan Sampah Berbasis Komunitas Menuju Ecohealthy Campus dan Desa Wisata Sehat Sugiyatmi, Tri Astuti; Saleh, Rachmat; Tamrin, Nasrullah; Seruni, Eka Nurul Hidayah Puspa; Awaluddin, Awaluddin; Egok, Adipura Atmadja; Rizky, Vincentia Ade; Rahayu, Avinda Sari Kanthi; Joni, Maria Selviana; Latifah, Umi; Laili, Ni'mah Hidayatul
Jurnal Medika: Medika Vol. 5 No. 1 (2026)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/m5mtm120

Abstract

Permasalahan pengelolaan sampah yang belum optimal masih menjadi isu utama di kawasan pesisir Kota Tarakan, khususnya di Kelurahan Pantai Amal yang berfungsi sebagai kawasan wisata sekaligus lokasi Kampus Universitas Borneo Tarakan. Wilayah ini juga merupakan sentra budidaya rumput laut, di mana penggunaan botol plastik sebagai pelampung berkontribusi terhadap timbulan sampah pesisir yang berdampak pada kesehatan lingkungan. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan, kesadaran, dan komitmen sosial petugas kebersihan Universitas Borneo Tarakan serta anggota Kelompok Swadaya Masyarakat (KSM) Tempat Pengolahan Sampah (TPS) 3R (Reduce, Reuse, Recycle) Amal Jaya dalam pengelolaan sampah berbasis prinsip 3R dan kesehatan lingkungan. Metode yang digunakan adalah pendampingan komunitas melalui penyuluhan interaktif, diskusi, pemberian media edukasi, serta demonstrasi pembuatan komposter metode Takakura. Evaluasi dilakukan secara deskriptif menggunakan pre-test dan post-test serta observasi partisipasi peserta. Kegiatan dilaksanakan dalam dua tahap pada 30 September dan 7 Oktober 2025. Hasil kegiatan menunjukkan tingkat pengetahuan peserta berada pada kategori tinggi, disertai peningkatan pemahaman dan keterlibatan aktif. Kegiatan ini menghasilkan komitmen kolektif untuk melanjutkan pendampingan KSM TPS 3R guna mendukung terwujudnya Ecohealthy Campus dan Desa Wisata Sehat Pantai Amal.
The Relationship Between Uric Acid Levels and Hypertension in Prolanis Patients at the Singandaru Public Health Center, Serang City Al Fina Nurhidayah; Syarah Anliza; Adipura Atmadja Egok; Dewi Maria Yuliani; Liu Zhi hong
Journal of Noncommunicable Diseases Prevention and Control Vol. 3 No. 1 (2025): Journal of Noncommunicable Diseases Prevention and Control
Publisher : Hypertension Prevention and Control Research Center, The Polytechnic of Health of Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61843/jondpac.v3i1.997

Abstract

Abstract Hypertension is a chronic disease with a continuously increasing prevalence in Indonesia, including in Serang City. One of the contributing risk factors for hypertension is high uric acid levels (hyperuricemia). An imbalance in the production and excretion of uric acid can lead to its accumulation in the blood, which in turn triggers an increase in blood pressure. The Prolanis (Chronic Disease Management Program) at Public Health Centers aims to manage chronic illnesses like hypertension in a more integrated manner. This study aimed to determine the relationship between uric acid levels and the incidence of hypertension in Prolanis patients at the Singandaru Public Health Center, Serang City. This was an analytical study with a cross-sectional design. The study population consisted of 92 Prolanis patients, from which a sample of 50 patients was taken. The results of the bivariate analysis of the two variables using the Chi-Square Test yielded a p-value of 0.000 (p < 0.05), which indicates a significant relationship between uric acid levels and hypertension in Prolanis patients. Thus, it can be concluded that there is a significant relationship between uric acid levels and hypertension in Prolanis patients at the Singandaru Public Health Center, Serang City.
Overview of Total Cholesterol Levels in Prolanis Hypertensive Patients at the Kelapa Dua Community Health Center Endah Cahya Nisa Anastasya; Syarah Anliza; Adipura atmadja Egok; Citra Trisna; Basil Okeahiam
Journal of Noncommunicable Diseases Prevention and Control Vol. 3 No. 2 (2025): Journal of Noncommunicable Diseases Prevention and Control
Publisher : Hypertension Prevention and Control Research Center, The Polytechnic of Health of Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61843/jondpac.v3i2.1000

Abstract

Hypertension is one of the non-communicable diseases whose prevalence continues to increase each year and contributes substantially to the risk of cardiovascular disease, especially when accompanied by high total cholesterol levels. This study aimed to describe total cholesterol levels among hypertensive patients participating in the Chronic Disease Management Program (Prolanis) at the Kelapa Dua Community Health Center, Tangerang Regency. This study used a descriptive design with a cross-sectional approach, and the sample consisted of 25 hypertensive Prolanis patients at the Kelapa Dua Community Health Center. Total cholesterol was examined using the CHOD-PAP method. The results showed that borderline-high total cholesterol levels by age were most common in the middle-aged group (45-59 years), with 7 respondents (64%), while 4 respondents (80%) had high cholesterol levels. Based on sex, high total cholesterol levels were found in 10 female respondents (91%) and 1 male respondent (9%). Based on the classification of total cholesterol levels by hypertension category, high total cholesterol was most frequently found in grade 1 hypertension, with 5 respondents (63%), while borderline-high cholesterol was found in 3 respondents (33%).
Efektivitas E-Modul Berbasis Video Terhadap Peningkatan Keterampilan Klinis Mahasiswa Pada Pembelajaran Skill Laboratory Laili, Ni'mah Hidayatul; Rahayu, Avinda Sari Kanthi; HPS, Eka Nurul; Rizky, Vincentia Ade; Joni, Maria Selviana; Latifah, Umi; Saleh, Rachmat; Awaluddin, Awaluddin; Tamrin, Nasrullah; Egok, Adipura Atmadja; Sugiyatmi, Tri Astuti
Science: Indonesian Journal of Science Vol. 2 No. 5 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/sciencejurnalkesehatanmasyarakatdanteknologiterapan.v2i5.403

Abstract

Pembelajaran keterampilan klinis pada mahasiswa kedokteran merupakan komponen penting dalam membentuk kompetensi profesional yang terstandar. Proses pembelajaran di skill laboratory sering menghadapi kendala, seperti keterbatasan waktu praktik, variasi kemampuan mahasiswa, serta kurangnya media pembelajaran yang dapat diakses secara fleksibel. . Pembelajaran keterampilan klinis di skill laboratory membutuhkan media yang efektif untuk menunjang peningkatan kemampuan mahasiswa. Penelitian ini bertujuan untuk menganalisis efektivitas e-modul berbasis video terhadap peningkatan keterampilan klinis mahasiswa. Metode penelitian menggunakan desain kuasi-eksperimen dengan pendekatan one group pre-test dan post-test design melalui kuesioner yang diberikan sebelum dan sesudah penggunaan e-modul pada mahasiswa. Data dianalisis secara deskriptif dengan membandingkan hasil sebelum dan setelah intervensi. Hasil menunjukkan adanya peningkatan pemahaman materi, keterampilan prosedural, serta kepercayaan diri mahasiswa dalam melakukan tindakan klinis. Sebagian besar responden juga memberikan penilaian positif terhadap kemudahan penggunaan, kejelasan materi, dan fleksibilitas akses e-modul berbasis video. Kesimpulan penelitian ini adalah e-modul berbasis video efektif dalam meningkatkan keterampilan klinis mahasiswa dan layak digunakan sebagai media pembelajaran pendukung pada kegiatan skill laboratory.
Co-Authors Al Fina Nurhidayah Avinda Sari Kanthi Rahayu Awaluddin Awaluddin Awaluddin Basil Okeahiam Citra Trisna Dewi Maria Yuliani Eka Nurul H.P.S Eka Nurul Hidayah Puspa Seruni Endah Cahya Nisa Anastasya HPS, Eka Nurul Laili, Ni'mah Hidayatul Liu Zhi hong Maria Selviana Joni Nasrullah Tamrin Rachmat Saleh Saleh, Rachmat Sugiyatmi, Tri Astuti Syarah Anliza Tri Astuti Sugiyatmi Umi Latifah Umi Latifah Vincentia Ade Rizky