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All Journal SENTRI: Jurnal Riset Ilmiah Celebes Journal of Community Services
Mulia, Reski
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Aerospace Engineering Humanities Computer Science & IT Economics, Econometrics & Finance Education Law, Crime, Criminology & Criminal Justice Social Sciences

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Penerapan Manajemen Berbasis Karakter Melalui Sosialisasi dan Pendampingan Budaya Kerja Pancawaluya untuk Meningkatkan Integritas SDM Sekolah. Mardiman, Mardiman; Taufik, Taufik; Tasa, Tyan; Firdaus, Muhamad Iqbal Ansori; Rasiwan, Iwan; Fathurrahman, Muhammad; Mulia, Reski; Nugraha, Yoga; Fachmi, Muhammad; Putra, Jeki Purnama
Celebes Journal of Community Services Vol. 5 No. 1 (2026): December - May
Publisher : STIE Amkop Makassar, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37531/celeb.v5i1.3473

Abstract

Pendidikan karakter melalui program Tatanen di Bale Atikan (TdBA) di Purwakarta telah berhasil membentuk karakter siswa, namun integritas SDM sekolah sebagai penggerak utama program masih menjadi tantangan. Pengabdian ini bertujuan meningkatkan integritas guru melalui penerapan manajemen berbasis karakter berbasis nilai Pancawaluya Welulang, Wawuh, Wani, Welas, dan Wiwaha melalui sosialisasi dan pendampingan partisipatif. Kegiatan dilaksanakan di SDN 3 Tegaldatar, Kecamatan Maniis, Kabupaten Purwakarta, pada 3-5 November 2025, dengan sasaran Tenaga Pendidik. Metode kualitatif partisipatif digunakan, meliputi observasi, diskusi kelompok terfokus, dan analisis tematik. Hasil menunjukkan peningkatan pemahaman nilai Pancawaluya dari rata-rata 36% sebelum kegiatan menjadi 90% setelah intervensi. Seluruh guru merumuskan “Deklarasi Budaya Kerja Pancawaluya” sebagai komitmen kolektif untuk transparansi, kolaborasi, dan keteladanan. Temuan membuktikan bahwa pendekatan berbasis nilai lokal yang partisipatif efektif memperkuat integritas profesional dan dapat direplikasi di sekolah TdBA lain.
Tinjauan Pustaka: Inovasi Formulasi Tablet Lepas Lambat Untuk Meningkatkan Kepatuhan Pasien Mulia, Reski; Fathurrahman, Muhammad
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 12 (2025): SENTRI : Jurnal Riset Ilmiah, Desember 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i12.5147

Abstract

Patient adherence to medication regimens is a crucial determinant of therapeutic success. Poor adherence remains one of the major causes of treatment failure, particularly in long-term therapies that require consistent and repeated drug administration. One effective pharmaceutical strategy to enhance patient compliance is the development of sustained-release drug delivery systems. These systems are designed to release active pharmaceutical ingredients gradually over an extended period, thereby maintaining therapeutic drug concentrations in the bloodstream while reducing dosing frequency. This systematic review aims to analyze recent innovations in sustained-release tablet formulations developed over the past decade and to evaluate their contribution to improving patient adherence. Literature searches were conducted across major scientific databases, including PubMed, ScienceDirect, and Google Scholar, covering publications from 2015 to 2025. The search employed the following keywords: “sustained release tablet,” “controlled release formulation,” “patient compliance,” and “pharmaceutical innovation.” A total of 32 articles met the inclusion criteria after rigorous screening and evaluation. The analysis revealed substantial advancements in formulation technology, particularly through the application of both natural and synthetic polymers such as hydroxypropyl methylcellulose (HPMC), carbopol, and chitosan. Furthermore, the integration of modern technologies—including 3D printing, matrix systems, and osmotic pump mechanisms—has significantly enhanced drug release efficiency, prolonged therapeutic duration, and minimized dosing frequency. Overall, sustained-release tablet formulations play a pivotal role in improving patient adherence, especially in chronic treatments, and continue to evolve alongside modern pharmaceutical innovations.
Sistematik Review: Jenis-jenis Gen yang Berpengaruh terhadap Penurunan Kadar Gula Darah pada Pasien Diabetes Melitus Tipe 2 Fathurrahman, Muhammad; Mulia, Reski
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 12 (2025): SENTRI : Jurnal Riset Ilmiah, Desember 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i12.5148

Abstract

Blood glucose reduction in patients with type 2 diabetes mellitus (T2DM) varies considerably among individuals, largely due to genetic factors that influence responses to antidiabetic drug therapy. This interindividual variability affects both the effectiveness and safety of commonly prescribed oral antidiabetic agents. Therefore, understanding the genetic determinants of treatment response is essential for optimizing glycemic control in patients with T2DM. This systematic review aims to identify genetic polymorphisms associated with variations in blood glucose reduction, particularly in patients receiving metformin, sulfonylureas, and other oral antidiabetic drugs. A comprehensive literature search was conducted using the PubMed, Scopus, and Google Scholar databases. A total of 880 articles were initially identified, of which 760 articles passed the preliminary screening based on title and abstract relevance. Following full-text screening using predefined inclusion and exclusion criteria, five studies were deemed eligible and included in the final analysis. The findings indicate that several genes play a major role in determining glycemic response to oral antidiabetic therapy, including SLC22A1 (OCT1), SLC22A2 (OCT2), SLC47A1 (MATE1), CYP2C9, KCNJ11, ABCC8, and TCF7L2. Genetic variations in these genes influence drug pharmacokinetics and pharmacodynamics, thereby contributing to differences in therapeutic effectiveness and glycemic outcomes among patients.
Co-Authors Firdaus, Muhamad Iqbal Ansori Jeki Purnama Putra Mardiman, Mardiman Muhammad Fachmi Muhammad Fathurrahman Nugraha, Yoga Rasiwan, Iwan Tasa, Tyan Taufik Taufik