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All Journal Jurnal Biologi Tropis Jurnal Riset Kefarmasian Indonesia
Sari, Tri Purma
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Review Article: Analysis of Drug-Related Problems (DRPs) in Diarrheal Disease Therapy Putranto, Diouf Maulana Dwi; Pebrianti, Dea Riski; Zaneta, Nabila Destia; Ulya, Tuhfatul; Hasina, Raisya; Sari, Tri Purma
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10968

Abstract

Diarrhea is one of the most common diseases in children and has the potential to cause various complications if not treated properly. Inappropriate treatment can trigger Drug Related Problems (DRPs) that affect the effectiveness of therapy. To identify and analyze the types of Drug Related Problems (DRPs) and recommended interventions in the treatment of diarrhea to support safe, effective, and rational drug use. A literature review was conducted by searching the PubMed and Google Scholar databases. A total of 10 articles that met the inclusion criteria were analyzed. The most common types of DRPs found were indications without therapy (7-45%), inappropriate dosing (both underdose 8-27% and overdose 7-35%), therapy without indication (10-85%), and drug interactions (12-56%). The main problems lie in the inaccuracy of clinical evaluation and irrational drug administration. DRPs in the treatment of childhood diarrhea are still common and have an impact on patient outcomes. Optimizing the role of pharmacists through medication reviews, dose adjustments, monitoring potential drug interactions, and educating health workers are key strategies for minimizing DRPs and improving treatment success.
POLA PENGGUNAAN DAN ANALISIS EFEKTIVITAS BIAYA OBAT ANTINYERI PADA PASIEN DIABETIK NEUROPATI DI RUMAH SAKIT ISLAM SULTAN AGUNG SEMARANG Sari, Tri Purma; Perwitasari, Dyah Aryani; Supadmi, Woro
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 3 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i3.390

Abstract

Diabetic neuropathy is gathering symptom clinic which influence system nerves, well single or combination and could happen in a manner suddenly, no detected, with symptom clinic and no specific signs but dangerous. Incidence diabetic neuropathy happen between 60% to 70% on type I and type II DM patients. Methods of data collection carried out prospectively. Data were obtained from outpatient data with a diagnosis of diabetic neuropathy who met the inclusion criteria and received analgetics from September to December 2020. Then a cost-effectiveness analysis was performed by calculating the ACER (Average Cost-Effectiveness Ratio) and ICER (Incremental Cost-Effectiveness Ratio) values. The results showed that the most commonly used analgetics was gabapentin at 65.96%, either alone or in combination with an effectiveness percentage of 83.87%. The use of analgetics with the lowest cost is a single Paracetamol of IDR 73,770. The lowest ACER values were shown in the use of the single analgetics Paracetamol and the combination of Amitriptyline-Paracetamol, namely 737.70 and 805.30.
Co-Authors Dyah Aryani Perwitasari Hasina, Raisya Pebrianti, Dea Riski Putranto, Diouf Maulana Dwi Ulya, Tuhfatul Woro Supadmi Zaneta, Nabila Destia