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Ulya, Tuhfatul
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PERBANDINGAN AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOL DAUN DAN BUAH JUWET (SYZYGIUM CUMINI (L.) SKEEL) PADA MENCIT HIPERURISEMIA Ulya, Tuhfatul; Rohmatillah, Siti; Muslichah, Siti; Ningsih, Indah Yulia
Jurnal Kefarmasian Akfarindo Vol 8 No 1 (2023)
Publisher : Akademi Farmasi Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37089/jofar.v8i1.202

Abstract

Penelitian ini bertujuan untuk mengetahui perbandingan aktivitas daun dan buah juwet (Syzygium cumini) sebagai agen antihiperurisemia pada mencit jantan hiperurisemia. Dua puluh tujuh mencit jantan dibagi menjadi sembilan kelompok yaitu KN sebagai kontrol negatif; K(-) sebagai kontrol negatif (diberi CMC Na 1%); K(+) sebagai kontrol positif (diberi allopurinol 10 mg/kg BB); P1, P2 dan P3 (setiap kelompok diberi ekstrak etanol 70% daun juwet dosis 140, 280, and 420 mg/kg BB). P4, P5 dan P6 (setiap kelompok diberi ekstrak etanol 70% buah juwet dosis 140, 280, and 420 mg/kg BB). Ekstrak diberikan pada mencit selama lima hari. Induksi hiperurisemia menggunakan melinjo 10% dari pakan standar mencit selama tujuh hari. Kaium oksonat 250 mg/kg BB diberikan dua jam sebelum pengambilan sampel darah. Kadar asam urat diukur menggunakan reagen DHBSA. Data yang didapat dianalisis menggunakan ANOVA satu arah dilanjutkan dengan uji LSD. Hasil yang didapat menunjukkan ekstrak etanol 70% daun dan buah juwet mampu menurunkan kadar asam urat pada mencit. Senyawa yang diduga sebagai antihiperurisemia adalah flavonoid, antosianin, asam fenolat, alkaloid, tanin dan terpenoid
Empowering public health awareness through dissemination of traditional medicine products Hardani, H.; Suhada, Adriyan; Ulya, Tuhfatul; Pertiwi, Ajeng Dian; Widyan, Rosnalia; Ratulangi, Wulan Ratia; Ammaranond, Palanee
Journal of Community Service and Empowerment Vol. 5 No. 1 (2024): April
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/jcse.v5i1.31929

Abstract

Traditional medicines have been an integral part of the cultural heritage and health systems of various societies around the world. To promote the use of traditional medicine and understand it more deeply, the dissemination of traditional medicine products is a crucial step. The purpose of this service is to explore the importance of the dissemination of traditional medicinal products and their benefits to the community.  The main target of this activity were people who have a history of chronic disease. In addition, public awareness to obtain information related to traditional medicine products was still lacking. The method of implementing this service activity was carried out by providing direct education related to traditional medicine to the community. As a result of the service, 19 traditional medicine products were disseminated and increased public awareness about traditional medicine. This result implies that the use of traditional medicine should be widely encouraged to a larger community.
SOSIALISASI PROSEDUR PEMERIKSAAN LABORATORIUM DAN TERAPI ANTIBIOTIK PADA PENYAKIT TUBERCULOSIS Mentari, Ika Nurfajri; Ustiawaty, Jumari; Aini, Aini; Idawati, Sri; Pertiwi, Ajeng Dian; Ulya, Tuhfatul; Hijriani, Baiq Isti
Jurnal Pengabdian Masyarakat Sehati Vol. 3 No. 1 (2024): Juni
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33651/jpms.v3i1.676

Abstract

Tuberkulosis (TBC) merupakan penyakit menular yang masih menjadi masalah kesehatan masyarakat utama di dunia, termasuk di Indonesia. Pengendalian TBC memerlukan pendekatan terpadu, meliputi diagnosis yang akurat melalui pemeriksaan laboratorium dan penanganan yang tepat dengan terapi antibiotik. Oleh karena itu, pemahaman yang baik tentang prosedur pemeriksaan laboratorium dan penggunaan antibiotik yang tepat sangat penting bagi tenaga kesehatan dan masyarakat. Kegiatan sosialisasi ini dilakukan di Udayana dalam rangka car free day dengan tujuan untuk meningkatkan pengetahuan dan keterampilan terkait prosedur pemeriksaan laboratorium TBC, seperti tes mikroskopis, tes cepat molekuler, dan tes biakan, serta prinsip-prinsip penggunaan antibiotik sesuai pedoman nasional dan rekomendasi terkini. Melalui penyampaian materi dan diskusi peserta akan memperoleh pemahaman yang mendalam tentang langkah-langkah pemeriksaan laboratorium yang benar, interpretasi hasil, dan cara pemberian terapi antibiotik yang optimal pada kasus TBC. Sosialisasi ini diharapkan dapat meningkatkan kualitas diagnosis dan tatalaksana TBC, serta mendukung upaya pengendalian penyakit ini di masyarakat.
Pharmacist Goes to School: Promoting DAGUSIBU As A Pharmaceutical Education Tool for Adolescents Saputra, Yoga Dwi; Ulya, Tuhfatul; Hasina, Raisya; Aini, Siti Rahmatul; Puspitasari, Candra Eka; Andanalusia, Mahacita; Lisnasari, Baiq Risky Wahyu; Hamdin, Candra Dwipayana
Jurnal Gema Ngabdi Vol. 6 No. 3 (2024): JURNAL GEMA NGABDI
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jgn.v6i3.522

Abstract

Drug misuse is an urgent public health issue, often arising from a lack of knowledge about proper medication use. Research shows that over half of the medications worldwide are used irrationally. The DAGUSIBU program (Dapatkan, Gunakan, Simpan, Buang or known as Get, Use, Store, Dispose) was developed as a solution to address this issue by providing education on proper medication management. This community service activity was organized by the Pharmacy Study Program and the Pharmacy Professional Education Program (PSPPA), Faculty of Medicine and Health Sciences (FKIK), Universitas Mataram, on August 9, 2024, at Kesuma Catholic High School in Mataram. The primary goal of this activity was to teach students the correct ways to obtain, use, store, and dispose of medications, as well as to introduce the pharmacist profession and the Pharmacy program at UNRAM to high school students. The activity included interactive presentations on DAGUSIBU, an introduction to the pharmacist profession, and a quiz competition as an evaluation method. The quiz encouraged active student participation, with prizes to boost motivation. Despite challenges such as varying levels of student comprehension and time constraints, the activity successfully improved students’ understanding of rational drug use and introduced career opportunities in pharmacy. Overall, this activity proved effective in raising student awareness and knowledge, positively impacting their health literacy.
EDUKASI PENCEGAHAN DAN PENANGANAN DIARE BAGI ANAK DI PANTI ASUHAN AL-IKHLAS AMPENAN Ulya, Tuhfatul; Budastra, Wayan Cintya Ganes; Hasina, Raisya; Safitri, Afifa Dian
Jurnal Abdi Insani Vol 12 No 6 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i6.2591

Abstract

Diarrhea is a common illness among children and remains a leading cause of death in children under five globally, including in Indonesia. The high incidence of diarrhea in children is often due to a lack of knowledge about its prevention and treatment. This activity aimed to increase the awareness of children at Al-Ikhlas Orphanage, Ampenan regarding the recognition, prevention, management, and dangers of diarrhea through a health promotion program. The method included a pre-test, interactive health education using posters, and a post-test. A total of 39 children participated in the activity. The average pre-test score was 63.5, which decreased to 61 in the post-test. This decline may be due to unfamiliar medical terms used during the session. However, the activity succeeded in raising basic awareness among the children about maintaining hygiene to prevent diarrhea. Simple and interactive health education should be further developed to improve children's understanding in orphanage environments.
Antioxidant Activity of Ethanol Extract Combination of Cavendis Banana Peel (Musa acuminata) and Kepok Banana Peel (Musa paradisiaca) Using the DPPH Method Suhada, Adriyan; Ulya, Tuhfatul; Fardani, Roushandy Asri; Pertiwi, Ajeng Dian; Halid, Idham; Pauzan, Pauzan; Ratulangi, Wulan Ratia; Indriani, Nurul; Ariwidiani, Ni Nyoman; Widyan, Rosnalia; Utami, Evi Fatmi; Novianty, Wanda
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol 13, No 3: July 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v13i3.15782

Abstract

Banana peels are often considered waste despite being rich in bioactive compounds with potential as natural antioxidants. This study aimed to evaluate the antioxidant activity of an ethanol extract combination of Cavendis banana peel (Musa acuminata) and Kepok banana peel (Musa paradisiaca) using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The extraction process was conducted using 96% ethanol maceration, yielding an extraction efficiency of 9.13%. Phytochemical screening revealed the presence of flavonoids, tannins, saponins, and steroids/terpenoids in the extract. Antioxidant activity was assessed through the DPPH method, resulting in an IC50 value of 6.47 ppm and an AAI value of 5.40, classified as very strong antioxidants. These results are comparable to the positive control (Vitamin C), which had an IC50 value of 6.29 ppm and an AAI value of 5.56. The findings suggest that the ethanol extract combination of Cavendis and Kepok banana peels has significant potential as a natural antioxidant source applicable in the food, pharmaceutical, and cosmetic industries. Recommendations for future research include optimization of extraction methods, isolation of key active compounds, in vivo testing, and functional product formulation development to maximize the extract's potential.
Physical Stability Evaluation of Topical Formulation Containing Turmeric (Curcuma longa L.) Leaf Extract as a Potential Natural Repellent Ulya, Tuhfatul; Ratnasari, Titin; Purmafitriah, En; Sasvania, Anisa
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9341

Abstract

Turmeric (Curcuma longa L.) leaves, rich in bioactive compounds like tannins, terpenoids, and essential oils, have potential as a mosquito repellent for preventing vector-borne diseases such as dengue, filariasis, and malaria. This study aimed to evaluate the physical stability of repellent lotion formulations containing ethanol extract of turmeric leaves. The research was experimental in nature. Two formulations were prepared using extract concentrations of 10% (F1) and 20% (F2). The turmeric leaves were extracted using the maceration method with 96% ethanol, yielding 4.069%. The physical stability of the repellent lotion was tested using the freeze-thaw method over 12 days, evaluating organoleptic properties, homogeneity, pH, adhesion, and spreadability. Organoleptic testing showed color differences between the formulas. After stability testing, the consistency of the lotions became slightly thinner. Both formulations exhibited good homogeneity. The pH values were within the safe range for skin application. Changes in adhesion and spreadability were influenced by the testing process. In conclusion, the repellent lotion formulations containing turmeric leaf ethanol extract demonstrated good physical stability and met required quality standards.
EDUKASI DAN DEMONSTRASI PEMANFAATAN TANAMAN KATANG-KATANG (IPOMOEA PES- CAPRAE) DALAM PENGOBATAN TRADISIONAL DI DUSUN MUARA PUTAT, DESA PEMENANG TIMUR, LOMBOK UTARA Hasina, Raisya; Aini, Siti Rahmatul; Hamdin, Candra Dwipayana; Ulya, Tuhfatul; Ananta, Muhammad Naufal Farras; Alamanda, Baiq Irzana Putri; Putri, Dheden Nurhani Bija; Yazid Maula
Jurnal Abdi Insani Vol 12 No 7 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i7.2704

Abstract

Ipomoea pes-caprae (katang-katang) adalah tanaman liar pesisir yang tersebar luas di wilayah tropis dan subtropis serta mampu beradaptasi di lingkungan berkadar garam tinggi. Perannya penting dalam ekosistem pantai, seperti mencegah erosi dan mendukung restorasi vegetasi. Daunnya umum digunakan secara tradisional untuk pengobatan gangguan pencernaan dan penyakit kulit. Di Dusun Muara Putat, Lombok Utara, tanaman ini belum dimanfaatkan secara optimal meski potensinya besar secara ekologis, terapeutik, dan ekonomis. Kegiatan ini bertujuan untuk meningkatkan wawasan dan keterampilan warga Dusun Muara Putat, Kabupaten Lombok Utara, dalam memanfaatkan katang-katang sebagai alternatif pengobatan tradisional. Pendekatan yang digunakan mencakup penyuluhan berupa sosialisasi dan praktik langsung. Kegiatan ini menggabungkan pendekatan sosialisasi dan praktik langsung, diawali dengan pre-test untuk mengukur pengetahuan awal peserta. Materi mencakup identifikasi morfologi tanaman katang-katang, kandungan bioaktif, manfaat farmakologis, dan teknik pengolahan sederhana. Peserta dilatih secara langsung, lalu dievaluasi melalui post-test untuk mengukur peningkatan pemahaman. Hasil menunjukkan peningkatan pengetahuan peserta, dengan rata-rata nilai pre-test sebesar 60 yang meningkat menjadi 80 pada post-test. Selain itu, peserta juga menunjukkan kemampuan praktik dalam mengolah tanaman untuk pengobatan rumah tangga. Penyuluhan melalui metode sosialisasi dan demonstrasi langsung dengan pendekatan partisipatif ini terbukti efektif dalam meningkatkan pengetahuan masyarakat Dusun Muara Putat tentang pengobatan tradisional, khususnya dalam pemanfaatan tanaman katang-katang (Ipomoea pes-caprae). Kesimpulannya, penyuluhan partisipatif di Dusun Muara Putat efektif meningkatkan pemahaman dan keterampilan masyarakat dalam pemanfaatan katang-katang sebagai obat tradisional.  
Antioxidant Activity of Ethanol Extract Combination of Cavendis Banana Peel (Musa acuminata) and Kepok Banana Peel (Musa paradisiaca) Using the DPPH Method Suhada, Adriyan; Ulya, Tuhfatul; Fardani, Roushandy Asri; Pertiwi, Ajeng Dian; Halid, Idham; Pauzan, Pauzan; Ratulangi, Wulan Ratia; Indriani, Nurul; Ariwidiani, Ni Nyoman; Widyan, Rosnalia; Utami, Evi Fatmi; Novianty, Wanda
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol. 13 No. 3: July 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v13i3.15782

Abstract

Banana peels, often considered agricultural waste, are rich in bioactive compounds with significant antioxidant potential. This study evaluates the antioxidant activity of a combined ethanol extract from Cavendis (Musa acuminata) and Kepok (Musa paradisiaca) banana peels using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The extraction was performed via maceration with 96% ethanol, yielding 9.13%. Phytochemical analysis identified key compounds including flavonoids, tannins, saponins, and steroids/terpenoids, which are known to exhibit antioxidant properties. The extract demonstrated strong radical scavenging activity with an IC50 of 6.47 ppm and an Antioxidant Activity Index (AAI) of 5.40, comparable to Vitamin C (IC50 = 6.29 ppm; AAI = 5.56). These results indicate a synergistic effect from combining the two banana peel varieties, enhancing antioxidant efficacy beyond that reported for individual peels. This study supports the potential use of Cavendis and Kepok banana peel extracts as sustainable natural antioxidants for application in food preservation, nutraceuticals, and cosmetics. Future work should focus on optimizing extraction methods, detailed phytochemical profiling, stability assessment, and in vivo validation to advance product development and maximize health benefits.
Literature Review: Exploration of Bioactive Components of Avicennia marina and Its Biological Activities Budastra, Cintya; Ulya, Tuhfatul; Maulidya, Selvira Anandia Intan; Purnomo, Indra; Lisnasari, Baiq Risky Wahyu; Permatasari, Lina
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7987

Abstract

Indonesia, as a maritime nation, possesses numerous mangrove ecosystems that have significant potential for exploring their benefits. One species of mangrove that has attracted attention is Avicennia marina, which contains various bioactive compounds. This article aims to provide a comprehensive review of the bioactive components of the Avicennia marina plant and its biological activities, particularly its therapeutic potential and benefits in the pharmaceutical field. We conducted a literature search to find relevant articles in the PubMed, Scopus, and Google Scholar databases using the keywords: plant identification + Avicennia marina; compound identification + Avicennia marina; biological activity + Avicennia marina. The bioactive content from the leaves, fruits, stems, and roots of Avicennia marina has been shown to exhibit antioxidant, antimicrobial, anticancer, and anti-inflammatory effects. This effect is strongly correlated to the presence of active metabolites of triterpenes, terpene alcohols, diterpenes, tannins, dodecanoic acid, octadecanoic acid, phenolic compound, flavonoid, squalene, and phytol. This indicates that Avicennia marina is a promising natural source for further research in the development of a new drug. Our finding further the notion of Avicennia marina as a potential medicinal plant.
Co-Authors Adriyan Suhada Aini, Aini Aini, Siti Rahmatul Ajeng Dian Pertiwi, Ajeng Dian Alamanda, Baiq Irzana Putri Ammaranond, Palanee Ananta, Muhammad Naufal Farras BaiqIsti Hijriani Budastra, Cintya Budastra, Wayan Cintya Ganes Candra Eka Puspitasari Fardani, Roushandy Asri Hamdin, Candra Dwipayana Hardani, H Hasina, Raisya Idham Halid Lisnasari, Baiq Risky Wahyu Mahacita Andanalusia Maulidya, Selvira Anandia Intan Mentari, Ika Nurfajri Ni Nyoman Ariwidiani Novianty, Wanda Nurul Indriani Pauzan Pauzan, Pauzan Permatasari, Lina Purmafitriah, En Purnomo, Indra Putri, Dheden Nurhani Bija Ratnasari, Titin Ratulangi, Wulan Ratia Rohmatillah, Siti Rosnalia Widyan Safitri, Afifa Dian Saputra, Yoga Dwi Sasvania, Anisa Sri Idawati ustiawaty, jumari Utami, Evi Fatmi Yazid Maula Yuni, Rohma