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REVIEW JURNAL : STUDI ETNOFARMASI TERHADAP PEMANFAATAN BAWANG PUTIH (Allium sativum) SEBAGAI TERAPI HERBAL HIPERTENSI Nisful Lailatun Nadiroh; Dwi Roisiyah; Nailah Mutiara Wahid; Nungki Hatit Isafani; Jesika Diah Pitaloka; Iftitah Nakhlah Sani; Wishnu Eka Adiwinata; Muhammad Rizky Imami; Farrel Darian Hafiz Fathan; Ivan Charles S.Klau
JURNAL ETNOFARMASI Vol. 3 No. 02 (2025): JURNAL ETNOFARMASI
Publisher : Universitas Pendidikan Muhammadiyah Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36232/jurnalfarmasiunimuda.v3i02.2690

Abstract

Hypertension, or high blood pressure, is a chronic medical condition characterized by an increase in systolic blood pressure ≥140 mmHg and/or diastolic ≥90 mmHg based on two measurements at rest. In the treatment of hypertension, in addition to pharmacological treatment, complementary therapy approaches based on medicinal plants are starting to gain attention because they are considered safer. Garlic is one of the most widely studied because of its bioactive compound content which has pharmacological activity, including in lowering blood pressure and as a natural antioxidant. The review was conducted using the method of collecting several national research journals and previously published literature. The sources used in this journal review are several journals that have been accredited by SINTA and also literature from the last 5 years. The search for articles and research journals was carried out using article search engines such as PubMed, ResearchGate, Google, and Google Scholar. The journal review conducted this time aims to see and find out how much potential the garlic plant has to act as an antihypertensive. The sources used in this review are journals that have been accredited. The results of several literature studies found that there was an effect of giving garlic herbal medicine to hypertension sufferers. The conclusion is that giving garlic infusion can lower blood pressure in hypertension patients.
Artikel Review : Pengaruh Penyalutan Terhadap Karakteristik Fisikokimia Tablet Salut Gula atau Enterik Nisful Lailatun Nadiroh; Dwi Roisiyah; Salsabiila Wina Delia; Najwa Firida Rahma; Adela Gerlani Bria; Rusdiana Tri Septiarini; Jihan Fahiroh Nur Arifin; Dewi Rahmawati; Yani Ambari; Dzakiya Zhihrotul Wida
Jurnal Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2026): Mei-Agustus
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v4i1.4596

Abstract

Tablet coating is one of the pharmaceutical technologies that plays an important role in improving the physicochemical characteristics and stability of tablet preparations. This study aims to comprehensively review the effect of coating processes on the physicochemical characteristics and stability of tablets, including mechanical properties, dissolution profiles, and active substance stability during storage. The method used is a literature review of 8 scientific journals obtained from Google Scholar, PubMed, PerpusNas, and ResearchGate databases, published within the last 5–10 years. The results showed that the coating process significantly affected physicochemical characteristics including hardness, friability, disintegration time, dissolution profile, and drug release. In terms of stability, coating protected active substances from environmental influences such as humidity, oxidation, and gastric acid degradation. Among the types of coating studied, enteric coating proved to be the most effective method as it provided maximum protection for acid-sensitive drugs and specifically controlled drug release in the intestine, thereby positively impacting bioavailability and therapeutic efficacy. Sugar coating also contributed to improving physical properties and protecting tablets during storage and distribution. Therefore, selection of appropriate coating type and composition is a critical factor in producing quality, stable, and therapeutically effective tablet preparations.