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All Journal Biotropika Panrita Abdi - Jurnal Pengabdian pada Masyarakat Medica Hospitalia Indonesian Journal of Health Science Jurnal Sains Biomedis Journal of World Future Medicine, Health and Nursing
Afifa Radhina
Department Of Physiology, Faculty Of Medicine, Universitas Pembangunan Veteran Jakarta, Jakarta, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Pathogenicity and characteristics of Blastocystis subtypes Nurul Ain; Afifa Radhina; Mike Permata Sari
Indonesian Journal of Health Science Vol 6 No 4 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i4.1698

Abstract

Blastocystis sp., an intestinal protozoan widely distributed in the human gastrointestinal tract, exhibits a global presence, with prevalence varying by region and generally higher in developing countries compared to developed ones. In Indonesia, reported prevalence varies considerably by region and study population, ranging from approximately 34% to 72% in several regional studies. This protozoan is water-borne and primarily transmitted through cysts via the fecal-oral route. Factors such as poor hygiene, immigration, travel to tropical developing countries, contact with animals, and consumption of contaminated food or water elevate the risk of infection. The pathogenesis in humans remains unclear, as infections may either manifest symptoms or remain asymptomatic, partly due to diagnostic limitations and variation in virulence across subtypes. This review aims to elucidate the characteristics and pathogenicity of Blastocystis sp. subtypes, particularly ST3, which is frequently dominant in symptomatic patients, and to discuss ongoing controversies in the literature.
HISTOPATHOLOGICAL IMAGE OF THE NUMBER OF NEURONS IN THE BRAIN OF MICE (MUS MUSCULUS) INDUCED BY LEAD HEAVY METAL Herera Rahajeng; Eka Sri Haryati; Ichwan Baihaki; Niken Rahmah Ghanny; Afifa Radhina; Assyafiya Salwa; Fransiskus Samuel Renaldi
Journal of World Future Medicine, Health and Nursing Vol. 4 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/health.v4i2.3677

Abstract

Lead is a known heavy metal from human history to date for various uses, abuses and toxicities. Lead poisoning has been recognized as one of the most serious environmental health issues worldwide, especially children living in developing countries. Lead can damage or affect the organs of the body, among others, the nervous system, kidneys, reproductive system, and heart, as well as disturbances in the brain so that intellectual and mental disorders in the brain. This study aims to see the effect of lead on the number of neurons in the hippocampus in mice experimental animals. The mice used amounted to 10 tails and divided into two for the control group and the treatment group. The control group, each of which was 5 tails, was then given unbleached drinking water while the treatment group was given drinking water mixed with acetate with concentration of 1000ppm for 17 days in adlibitum. The observations were taken from each of the 5 fields of view on each preparation with a magnification of 40x. The calculation of the number of neuron cells is then analyzed descriptive statistics and different test. The result showed that control group with mean ± SD were 127,6 ± 7,9, and for treatment group that was 80,0 ± 20,9. T independent test result showed p = 0,001 (p <0,05) which means that there was a significant difference between control and treatment group. The conclusion of this research is the existence of neuron cell damage in mice that get treatment. By showing the number of neurons less than the control mice. Suggestion to develop this research hence need to continue research to find neuro protector compound specially from lead work in brain.
Co-Authors Amalia Shari Arianto, Steven Assyafiya Salwa Cityta Putri Kwarta Eka Sri Haryati Ichwan Baihaki Indriani, Narita Insani Fitrahulil Jannah Jannah, Insani Fitrahulil Muhammad Fadhil Niken Rahmah Ghanny Niken Rahmah Ghanny Nisa Kartika Komara Nurul Ain Pararawendy Indarjo Privia Muliamarshanti Rahajeng, Herera Renaldi, Fransiskus Samuel SARI, MIKE PERMATA Shari, Amalia Steven Arianto