Jurnal Ilmiah Kedokteran Wijaya Kusuma
Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.
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390 Documents
<![CDATA[Pengaruh Ekstrak Undur-undur (Myrmeleon sp) terhadap Glukosa Darah dan Hematokrit pada Tikus Diabetes ]]>
<![CDATA[Djap Hadi susanto]]>;
<![CDATA[Ronald Winardi Kartika]]>;
<![CDATA[Pamela Hendra Heng]]>;
<![CDATA[Adit Widodo Santoso]]>;
<![CDATA[Maria VB Lopulalan]]>;
<![CDATA[Angelina Wijaya]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 2 (2020): SEPTEMBER 2020 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v9i2.863
<![CDATA[Diabetes Mellitus (DM) is one of the major health problems in the world and Indonesia. The prevalence is more increasing and also shows the trend of events is shifting to young age. Diabetes mellitus treatment requires high costs and also a lifetime. Most of the people of Indonesia still use traditional methods of treatment, especially herbs from various biological substances that are available in the environment. Undur-undur (myrmeleon sp.) is believed to have the effect of anti-hyperglycemia, and also anti-viscosity. The aim of this study was to determine anti-hyperglycemia and anti-viscosity of myrmeleon sp. extract in diabetic rats. The design of study is randomized experiment. Diabetic rats were induced by streptozocin 100mg/ kg BW intraperitoneal. Fifty rats were divided into 2 groups administered by Myrmeleon sp. extract dose 0,01ml/ 200 gram BW (100%) and 0,005ml/ 200 gram BW (50%). Myrmeleon sp. shows the effect of anti-hyperglycemic and anti-viscosity in diabetic rats. There was a difference between 50% and 100% doses. The effect of anti-hyperglycemia and anti-viscosity occurs after the second day. Conclusion: the extract of myrmeleon sp. could be considered as one of the traditional treatments of diabetic patients.]]>
<![CDATA[SJOGREN'S SYNDROME ]]>
<![CDATA[Febtarini Rahmawati]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v1i1.50
<![CDATA[Sjogren's syndrome merupakan salah satu jenis penyakit auto imun non spesifik organ yang sering terjadi secara bersamaan dengan penyakit auto imun lainnya. Sebagian besar diderita oleh wanita usia diatas 40 tahun, dengan gejala kelenjar air liur dan air mata kering. Pemeriksaan laboratorium penyaring penyakit auto imun adalah ANA (anti nuklir antibodi) test. Bila pemeriksaan ANA (anti nuklir antibodi) positif, dilanjutkan pemeriksaan konfirmasi auto antibodi imunoblotting, untuk mengetahui konsentrasi band antibodi anti-SSA/antibodi terhadap sjogren's syndrome antigen A (Ro) atau antibodi anti-SSB/antibodi terhadap sjogren's syndrome antigen B (La) yang positif.]]>
<![CDATA[ASPECT NEUROLOGICAL ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD) ]]>
<![CDATA[Agung Budi Setyawan]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2010): Edisi Januari 2010 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v2i1.78
<![CDATA[Until now there is no theory that says the exact cause of ADHD, but some theories say there are various contributing factors, including: genetic, minimal brain damage, neurobilogi, neurokimiawi, psychosocial, food, et cetera. In the last decade considerable amount of research that proves that neurological factors have a role and a significant influence on the development of ADHD. That's why understanding the neurological aspect of ADHD is needed to be done as early handling and seholistik possible so that it can reduce the negative impacts that can occur both in children with ADHD, parents, schools, and communities. ]]>
<![CDATA[HUBUNGAN ANTARA KELEBIHAN BERAT BADAN DENGAN KEKUATAN TULANG PEREMPUAN LANSIA ]]>
<![CDATA[Denina Kusumaningayu Puspitarini]]>;
<![CDATA[Basuki Supartono]]>;
<![CDATA[Yuli Suciati]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 10, No 2 (2021): SEPTEMBER 2021 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v10i2.1197
<![CDATA[Osteoporosis merupakan salah satu penyakit degeneratif yang banyak terjadi pada perempuan lansia. Terdapat beberapa faktor risiko diantaranya adalah usia dan indeks massa tubuh. Berat badan berlebih pada lansia dapat mempengaruhi kekuatan tulang yang mungkin memberikan efek protektif, sehingga penelitian ini bertujuan untuk mengetahui hubungan antara kelebihan berat badan (overweight dan obesitas) dengan kekuatan tulang perempuan lansia. Penelitian ini merupakan observasional analitik dengan desain potong lintang dan pendekatan korelasi. Dengan teknik acak sederhana, sejumlah 104 perempuan lansia dihitung indeks massa tubuh menggunakan timbangan dan staturameter serta diukur kekuatan tulangnya menggunakan BMD (Bone Mineral Densitometry) jinjing sebagai deteksi dini osteoporosis, yang dilakukan di Rumah Sakit Umum Al-Fauzan, Kota Jakarta Timur, pada bulan Oktober 2019. Hasil penelitian didapatkan subjek overweight sebanyak 77 orang (74%) dan obesitas 27 orang (26%). Dari subjek overweight terdapat 68 orang (88,3%) menderita osteoporosis, dan 9 orang (11,7%) menderita osteopenia. Dari subjek obesitas 22 orang (81,5%) menderita osteoporosis dan 5 orang (18,5%) menderita osteopenia. Berdasarkan uji Chi-Square dari kedua varibel, dapat disimpulkan bahwa penelitian ini tidak menunjukkan hubungan yang bermakna antara kelebihan berat badan dengan kekuatan tulang perempuan lansia, p= 0.512 (derajat kemaknaan < 0.05). Kelebihan berat badan seperti overweight ataupun obesitas mungkin tidak dianggap sebagai faktor pelindung terhadap osteoporosis pada perempuan lanjut usia.]]>
<![CDATA[EFFECT OF SEED EXTRACT JUWET (Eugenia JAMBOLANA) DECREASE OF BLOOD GLUCOSE CONCENTRATION IN MICE BALB / c MALE THAT INDUCIBLE STREPTOZOTOCIN ]]>
<![CDATA[Inawati Inawati]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2010): Edisi Januari 2010 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v2i1.81
<![CDATA[Acording to the data in the journal of Diabetes Care 2004, DM patient in Indonesia in 2000 reach 8,4 million people. And ranked 4th after India, Cina and USA. Population will increase more than two times in 2030, reach 21,3 million people. This study was to prove effect of extract juwet seed in blood glucose level in mice after induction of Streptozotocin (STZ). This was experimental study using white male BALB/c strain mice, 10 weeks old with bodyweight of 25-35 grams. Group 1 was received no STZ and extract juwet seed sacrified in 3th day. Group 2 was received STZ but no extract juwet seed , sacrified in 3th day. Group 3 was received STZ but no extract juwet seed, sacrified in 18 th day. Group 4 was received STZ and received extract juwet seed. Group 5 was received no STZ and extract juwet seed, sacrified in18th day. Fasting blood glucose and 2 hours after given oral glucose was examined in 3th day and in 18th day. There was significant difference between group those received STZ and received no extract juwet seed and those that received STZ but received no extract juwet seed in the result of Anova analyzed for fasting blood glucose level (p<0,05) and Anova analyzed showed significant difference (p<0,05) between blood glucose level 2 hours after given glucose who received STZ but received no extract juwet seed and those who received STZ and received extract juwet seed. The conclusion of this experiment was the level of fasting blood glucose and level blood glucose 2 hour s after given glucose of mice who received STZ and received no extract juwet seed less than in mice who received STZ and received extract juwet seed. ]]>
<![CDATA[Deskripsi Belajar Anatomi Tingkat Kesulitan pada Sistem Online dan Offline Mahasiswa Fakultas Kedokteran, Wijaya Kusuma Surabaya ]]>
<![CDATA[Rieke Aurellia]]>;
<![CDATA[Ayly Soekanto]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 1 (2022): MARET 2022 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v11i1.1715
<![CDATA[Anatomy is a basic science that is learned in medical education as a basis related to clinical skills in the skills to become a doctor. The Covid-19 outbreak has changed the entire education system. The Covid-19 pandemic has changed the shape of the education model at universities until the Faculty of Medicine is closed. The COVID-19 pandemic has changed the pattern of the learning system, from which the offline model was changed to online. This learning pattern forces students to usually participate in online activities. Bring up the pattern of levels that appear in the two models of this learning system. The cross sectional method and observational research were then analyzed and the descriptions were observed. simple random sampling method was used in this study. The purpose of this research is to understand descriptive anatomy learning, seen from the level that appears in students' difficulties, obtained from 20 questionnaires consisting of 7 categories, namely: understanding, effectiveness, good communication, learning hours, clear material, easily accessible lectures. There were no students who took part in the remedial course (RC). From the results of filling out the questionnaire and processing the data, it can be concluded that there is no picture of the difficulties between the two learning systems, namely online and face-to-face.]]>
<![CDATA[Peranan Stres Oksidatif pada Proses Penyembuhan Luka ]]>
<![CDATA[Handy Arief]]>;
<![CDATA[M Aris Widodo]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 5, No 2 (2016): Edisi September 2016 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v5i2.338
<![CDATA[Wound healing is a complex dynamic process characterized by a series of events that occur in almost all type of tissue damage. In the early phase of the inflammatory response, neutrophils and macrophages enters into the injured tissue and the cells produce reactive oxygen species that can give a beneficial or detrimental effects. Oxidative stress is a condition occurs that shows imbalance between prooxidant or free radical and antioxidant that have a function to maintain the condition of the tissue damage that occurs. So Oxidative stress occurs when the production of Reactive Oxygen Species occurring is higher than the antioxidants existing as an intrinsic defense. Reactive Oxygen Species and Reactive Nitrogen Species are important components in the healing process of wounds and is necessary to be in the state of homeostasis to prevent oksidatif stress. The major components of ROS are superoxide (O2•), hydroxyl radical (OH•) and hydrogen peroxide (H2O2), which includes RNS are nitric oxide (NO•), nitrous oxide (NO2•), nitroxyl anion (HNO) and peroxynitrite (ONOO-) which could be form by the reaction between superoxide and nitric oxide. The existence of excessive O2 amount in the wound and the presence of excess NO can increase the incidence of oxidative stress that interfere with wound healing process. Oxidative stress plays a role in the inflammatory phase, proliferation and remodeling phase by increasing angiogenesis and affect other cells including endothelial cells in secreting NO. So the strategy in controlling oxidative stress is by increasing antioxidant level which is a scavenger to free radical excessive superoxide formation so preventing interference with the wound healing process. ]]>
<![CDATA[PENATALAKSANAAN PADA DIABETIC PERIPHERAL NEUROPATHIC PAIN (DPNP) ]]>
<![CDATA[Herni Suprapti]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma No 1 (2011): Edisi Juli 2011 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v0i1.2144
<![CDATA[Penyebab diabetic peripheral neuropathic pain (DPNP) masih belum diketahui, dan nyeri yang dirasakandapat sangat hebat sehingga mengganggu aktivitas. DPNP tidak dapat disembuhkan, tetapi untukmemperbaiki kualitas hidup, perlu diberikan terapi untuk mengontrol nyeri, yaitu dengan memberikanobat topikal, obat oral, serta tindakan non-farmakologi lain (akupunktur dan transcutaneous nervestimulation). Diabetic peripheral neuropathic pain (DPNP) mengenai sekitar 10% sampai 20% dari 20 juta pendudukAmerika yang menderita diabetes mellitus (DM) (1,2).]]>
<![CDATA[Water Clover Extract in Liprotein Lipase enzyme Activity of The Rats with High Cholesterol Diet ]]>
<![CDATA[Dewinta Hayudanti]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 7, No 2 (2018): Edisi September 2018 ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v7i2.429
<![CDATA[Hypertriglyceridemia or high blood triglyceride levels is one of the lipid fraction disorders associated with an increased risk of cardiovascular disease. Flavonoids has an important role as cardioprotection by lowering triglyceride levels. The flavonoids in water clover contain 10,71 mg of extract. This research aims to prove that flavonoids can increase Lipoprotein Lipase enzymes activity. True experimental study used design pre-post test control group design in rats. The sample was selected based on by completed randomized design sampling to be devided into five groups, the control positive (n=5) were only given normal diet, control negative (n=5) were only given high cholesterol diet and treatment groups with three doses (n=15) were given cholesterol diet during the 7 days and water clover extract that intervention during the 14 days. The results of this research can increase activity of Lipoprotein Lipase enzymes as an influence of water clover extract based on Paired T-Test, before and after treatment there was a significant different (p<0.05). Activity of Lipoprotein Lipase enzymes in the negative control group and third treatment showed a significant difference (p.< 0.05) based on MANOVA (Multivariate Analyses of Variance). Conclusions of this research is water clover extract affecting increase Lipoprotein Lipase enzymes activity significantly.]]>
<![CDATA[Relationship between Education, Sex, and Age with Refractive Errors at DR. Wahidin Soedirohusodo General Hospital ]]>
<![CDATA[Kadek Dwipa Dyatmika]]>;
<![CDATA[Nurmawanti Nurmawanti]]>;
<![CDATA[Rini Kusumawar Dhany]]>
<![CDATA[ Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 8, No 1 (2019): EDISI MARET 2019 (available online since April 2019) ]]>
Publisher : <![CDATA[Universitas Wijaya Kusuma Surabaya ]]>
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DOI: 10.30742/jikw.v8i1.479
<![CDATA[The prevalence of refractive error and its relationship with education, age and sex at DR. Wahidin Soedirohusodo general hospital have not been comprehensively assessed. The aim of this study was to examined the distribution and risk factor of refractive errors at DR. Wahidin Soedirohusodo general hospital. Methods of this study used population based cross-sectional study. Respondents were interviewed and underwent standardised clinical eye examinations. Refractive error was determined by an automatic refraction device. Refractive errors are myopia, hyperopia and astigmatism. Myopia and hyperopia were defined as spherical equivalent of -0.50/+0.50 diopter (D) or worse, respectively; astigmatism was defined as cylindrical error >0.50 D. Total of 1760 patients with refractive error from January 2016 to January 2018 with 700 or 39,8% males and 1060 or 60.2% females. Based on the cross-tabulation output, it is known that the respondents with the most elementary level of education experienced mild hypermetropy (10.2%), the junior high school education experienced mild myopia (6.8%), high school and bachelor education experienced mild myopia (8%). Age 6-15 years experienced the most myopia compositus astigmatism (5.7%), 16-25 years mild myopia (10.2%), 26-35 years mild myopia (4.5%), 36-45 years mild myopia (10.2%), 46-55 years mild hypermetropia (10.2%) and 56-65 years mild hypermetropia (5.7%). Kruskal Wallis test it is known that the sig value obtained = 0,000 indicates that there are differences in refractive abnormalities based on education and age. Chi square sig value obtained is 0.021, indicating that there is a relationship between sex and refractive errors. Multivariate analysis revealed female subjects inhibited the risk of mild myopic by 0.157 times the male subjects and simple myopia astigmatism by 0.082 times the male subjects. The relationship of myopia, astigmatism and hypermetropia with age and education is not significant. The risk factor of mild myopia and simple myopia astigmatism decrease in female than male. These findings may help clinicians to better understand the patterns of refractive error and planning for preschool vision-screening programs.]]>
