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Jurnal Ilmiah Kedokteran Wijaya Kusuma

JIKW
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Published by Universitas Wijaya Kusuma Surabaya

ISSN : 19782071 EISSN : 25805967 DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.

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Articles 390 Documents

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The giving effects of biscuits and tempeh-based flour cakes as supplemetary feeding towards improvements in body weight and height in children suffering malnutrition 2015 Oktovina Rizky; Bambang Wirjatmadi; Merryana Adriani
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 1 (2015): edisi September 2015
Publisher : Universitas Wijaya Kusuma Surabaya

Background: Nutritional problem in children is considered as a major issue and one that should receive priority in treatment is concerning to malnutrition. Malnutrition in children occurs due to insufficiency in energy and protein. Energy and protein are required in supporting rapid growth in children.Objective: to learn the giving effects of biscuits and tempeh-based flour cakes as supplementary feeding towards improvements in body weight and height of children under five suffering malnutrition in one of Public Health Center working area, northern region of Kediri Municipality.Methods: This study used a Randomized Control Triall Design, towards groups of children under five by providing tempeh-based flour cakes for supplementary feeding in the treatment group and by providing biscuits for supplementary feeding in control group. Samples were as many as 30 children under five and the data were being analyzed using peason and pre-post differences analysis was done using paired samples T-testResult: There was significant difference between body weight and body height after provision of providing biscuits and tempeh-based flour cakes for supplementary feeding with p = 0.001 (p <α) for the treatment group and p = 0.001 (p <α) for the control group.Conclution: Providing and tempeh-based flour cakes in the treatment group for 30-days gave influence on increasing body weight and height.

Puasa Selama Kebuntingan terhadap jumlah sel neuron Cereberum dan Cerebellum Rattus norvegicus Baru Lahir Ucik Nurul Hidayati; Hermanto Tri Joewono; Muhammad Miftahussurur; Agus Sulistyono; Martono Tri Utomo; Sulistiawati Sulistiawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 1 (2020): MARET 2020 available online since April 2020
Publisher : Universitas Wijaya Kusuma Surabaya

Fasting by pregnant women causes increasing neurons in the brain. An increasing number of neuron cells will speed up information processing, so it is expected to increasing intelligence. The purpose of this study was to analyze the effect of fasting during pregnancy on the number of new cells of the cerebrum neuron and the newly born Rattus norvegicus cerebellum. The research design was true experimental laboratory posttest only with control group design. Pregnant Rattus norvegicus samples consisted of 3 groups and 1 control group with a total sample of 32 divided by 4; Xo control group without fast treatment, fasting X1 group in 1st trimester (2 days), fasting X2 group in 2nd trimester (2 days), fasting group X3 at TM 3 (2 days). Data analysis using Shapiro – Wilk normality test, followed by ANOVA test and using SPSS for Windows 23 software. The results of statistical analysis showed no significant difference in the number of cerebrum neuron cells in the four groups P = 0.210 (p> 0.05) and there were significant differences in the number of cerebrum neuron cells in the four groups P = 0.032 (p <0.05). The conclusion of this study is there was no difference in the number of neuron cells in cerebrum and cerebellum of Rattus norvegicus newborn in the fasting mother 2 days during trimester I, II dan III of pregnancy. There was a difference in the number of neuron cells in the new cerebellum of Rattus norvegicus fasting for 2 days during trimester III of pregnancy, and there were differences the effect of the number of neuron cell in cerebellum of Rattus norvegicus in all groups.

Bell's Palsy Olivia Mahardani Adam
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 8, No 1 (2019): EDISI MARET 2019 (available online since April 2019)
Publisher : Universitas Wijaya Kusuma Surabaya

Bell’s palsy didefinisikan sebagai kelumpuhan saraf fasialis satu sisi, dengan penyebabnya tidak diketahui. Beberapa keadaan lain juga dapat menyebabkan kelumpuhan fasialis, misalnya tumor otak, stroke, myasthenia gravis, dan penyakit Lyme. Namun, jika tidak ada penyebab khusus yang dapat diidentifikasi, kondisi ini dikenal sebagai Bell’s palsy yang disebabkan akibat pembengkakan dan tekanan saraf pada foramen stylomastoid dan menyebabkan penghambatan atau kerusakan saraf. Seringkali mata di sisi yang terkena tidak dapat ditutup, lipatan nasolabial dan garis dahi menghilang. Kortikosteroid ditemukan untuk memperbaiki hasil ketika digunakan lebih awal, sementara obat anti-virus belum. Banyak yang menunjukkan tanda perbaikan 10 hari setelah onset, bahkan tanpa pengobatan. Artikel ini bertujuan untuk mengulas Bell’s palsy terutama patofisiologinya. Tingkat keparahannya syaraf menentukan proses penyembuhan Bell’s palsy.

Use of classification and regression tree (cart) for chronic periodontitis classification in dental hospital of Hang Tuah University Surabaya Aulia Dwi Maharani
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

Classification and Regression Tree (CART) is now commonly used as one of nonparametricclassification methods. The advantage of this method is it can effectively used on data whichhave many independent variables. It is also easy to be interoperated.The aim of this research is to classify Chronic Perodontitis in Dental Hospital of Hang TuahUniversity Surabaya using CART. The Chronic Periodontitis divided into 3 categories: mild,moderate, and heavy. Based on the analysis result, 2 factors can affected the mild type ofchronic periodontitis , 6 factors affected moderate type of chronic periodontitis and 8 factorsaffected the heavy type of chronic periodontitis.The criteria used to count the accuracy of the CART classification is 1-APER. The 1-APERscore shows a very good result which is 92,5% for data learning and 90% for data testing.

Gambaran Doppler Ultrasound dengan Diuresis dibandingkan dengan hasil renogram untuk membedakanuropati ostruktif dan non obstruktif Sianny Suryawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 3 (2011): Volume Edisi Khusus Desember 2011
Publisher : Universitas Wijaya Kusuma Surabaya

Ultrasonografi merupakan modalitas pemeriksaan awl dalam dignosis obstruksi ginjal.

Potensi Jus Buah Naga Merah (Hylocereus polyrhizus) terhadap Perbaikan Jaringan Organ Otak Tikus (Rattus norvegicus) Diabetes I Gede Gelgel Bayu Surya Putra; Dorta Simamora
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 8, No 2 (2019): EDISI SEPTEMBER 2019 (available online since Oktober 2019)
Publisher : Universitas Wijaya Kusuma Surabaya

Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to disturbances in insulin secretion, insulin action, or both. The purpose of this study was to analyze the effect of the red dragon fruit juice (Hylocereus polyrhizus) to repair brain organ histopathologic female wistar rats (Rattus norvegicus Wistar strain) with diabetes. This research is a true experiment research with randomized control - group pretest - posttest design and were conducted at the in Vivo Laboratory of Wijaya Kusuma University Surabaya. Twenty five female wistar rats were randomly divided into 5 groups, normal rats group KA (without alloxan induction), diabetic rats group KB (alloxan induction and without given any red dragon fruit juices), treatment group KC (alloxan induction + 2 gr/2,5ml of red dragon fruit juices), treatment group KD (alloxan induction + 4 gr/2,5ml of red dragon fruit juices) and treatment group KE (alloxan induction + 8 gr/2,5ml of red dragon fruit juices). The study was conducted during the period of 16 days with standard feeding adaptations for 7 days. On day 16, all the rats were terminated. Glucose meter is used to measure the levels of blood glucose in rats. Histopathologic observation of rat brain tissue using a microscope Olympus CX21 with Haematoksilin eosin (HE) staining. The results showed the best dose of red dragon fruit juices to decrease blood glucose levels compare between KB and KE with significance p-value = 0.000 (α < 0.05), the blood glucose levels decreased in diabetic rats significantly between KB and KE also decreased in rat brain tissue necrosis with p-value = 0.000 (α <0.05).

Monitoring of Patient With Diabetes Mellitus Widodo Widodo
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 2 (2014): edisi Oktober 2014
Publisher : Universitas Wijaya Kusuma Surabaya

Diabetes mellitus is a disease characterized by hyperglycemia, which is caused by impaired insulin secretion, impaired insulin action, or both. Chronic hyperglycemia will lead to dysfunction and damage to various organs, such as the eyes, kidneys, nerves, heart, and blood vessels. This paper discusses the monitoring of patients with diabetes mellitus according to the laboratory tests, to know when the results of therapy has reached the optimum point as well as the prevention of complications that can occur.

Literature Study: The Effect of Giving Chitosan Water Gel (Hydrogel) on Healing Diabetic Ulcers Based on In Vivo Studies with Animal Models Zahratul Noreisza Rakhmadi; Erina Yatmasari; Prawesty Diah Utami
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 11, No 2 (2022): SEPTEMBER 2022
Publisher : Universitas Wijaya Kusuma Surabaya

Diabetic ulcers are one of the most common chronic complications and cause infection, gangrene to leg amputation if the treatment given is not appropriate. Chitosan has anti-microbial properties that make the wound area smaller and are anti-inflammatory to reduce pain. Water gel (hydrogel), which is water, is easily absorbed by the skin and penetrates perfectly into the wound so that it provides a moist effect and prevents bacteria from entering. This study aims to determine the effect of giving chitosan water gel (hydrogel) on the healing of diabetic ulcers. This study uses a literature study method by searching for related journals using keywords, then selected based on the last 5 years and indexed in SINTA, Google Scholar or Scopus, and the final results are 13 journals. This study took place in May - November 2021. The results of this study reported that the administration of chitosan water gel (hydrogel) combined with other ingredients for healing diabetic ulcers gave the same results. The results obtained are reducing inflammation, re-epithelializing wounds, accelerating angiogenesis, accelerating the formation of collagen and granulation tissue, and accelerating wound healing. Although all studies have the same results, the healing time produced by each study is different, this is because each ingredient used has a different content. The average wound changes were seen on the 3rd, 5th, 7th day and the wound healed completely on the 14th day. This study concludes that the administration of chitosan water gel (hydrogel) affects the healing of diabetic ulcer wounds in combination with other ingredients. because the time needed to close the wound is faster.

ASPEK LABORATORIUM Acute Promyelocytic Leukemia (APL) AML-M3 Febtarini Rahmawati
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2013): Edisi Mei 2013
Publisher : Universitas Wijaya Kusuma Surabaya

Acute Promyelocytic Leukemia (APL) adalah subtipe M3 dari Acute Myelogenous Leukemia (AML), sesuai klasifikasi French-American-British (FAB). APL mempunyai beberapa varian yang bisa dibedakan dari pemeriksaan molekular dan sitogenetika. Lebih dari 95% APL hipergranular (M3 klasik), 15%-20% dari APL adalah varian mikrogranular (hipogranular, M3v) dan varian APL yang jarang (<1%) adalah basofilik dan Promyelocytic leukemia zinc finger (PLZF/M3r).Gejala klinis penderita APL yakni anemia meliputi pusing, kelelahan, sesak ketika kerja fisik, pucat. Perdarahan terjadi karena pasien dengan APL mengalami penurunan jumlah trombosit dan gangguan sistem koagulasi. Sel darah putih pada umumnya meningkat ditandai dengan gejala panas badan dan infeksi serta pembesaran limpa juga nyeri tulang akibat infiltrasi sel-sel leukemia ke periosteal.Tes skrining penderita leukemia akut adalah pemeriksaan darah rutin dan evaluasi sediaan hapusan darah tepi. Pemeriksaan penunjang diagnostik lainnya adalah hapusan dari aspirasi sumsum tulang, pengecatan sitokimia, Immunophenotyping, sitogenetika dan biologi molekular. White blood cell (WBC) > 10 X 109/L, trombositopenia < 50 X 109/L. Hapusan darah tepi pasien dengan APL didapatkan gambaran eritrosit normokromik normositik dengan poikilositosis dan kadang-kadang normoblas. Gambaran sel-sel muda didominasi oleh promielosit. Sebagian besar hipergranular, morfologi mieloblasnya dengan nukleus berlekuk dan Auer rod. Pada hapusan sumsum tulang umumnya hiperseluler dengan jumlah sel-sel muda promielosit ≥30%. Morfologi promielosit pasien dengan APL lebih besar daripada promielosit normal. Auer rods positif kadang-kadang didapatkan faggots cell. Aktivitas eritropoiesis dan trombopoiesis tertekan. Varian hipergranular APL diketahui dengan pemeriksaan sitokimia, immunophenotyping, sitogenetika dan teknologi biologi molekuler.

Pengaruh Ekstrak Anggur Laut terhadap pH Lambung dan duodenum pada Rattus norvegicus Jantan yang Diinduksi Indometasin Ardilon Raxel Faruwu; Riami Riami; Fitri Handajani
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 9, No 2 (2020): SEPTEMBER 2020
Publisher : Universitas Wijaya Kusuma Surabaya

Indomethacin is a nonsteroidal anti-inflammatory drugs (NSAIDs) that act to inhibit COX-1. The inhibition of COX-1 leads to inhibition of prostaglandin production. Prostaglandin is a regulator of gastric acid buffer secretion. Inhibition of prostaglandin decrease gastric and duodenum pH and damage the gastric and duodenum. Sea grapes (Caulerpa racemose var. cylindracea) are marcoalgae that contain flavonoids as antioxidants and anti-inflammatory. The aim of this study was to determine the effect of sea grapes on gastric and duodenum pH in rattus norvegicus induced by indomethacin. 32 male Rattus norvegicus were divided into 4 groups. Group K (-) without treatment. Group K (+) was induced by 30 mg/Kg BW indomethacin for 7 days. Group P1 was induced by 30mg/Kg BW indomethacin for 7 days followed by administration of 1g/100g BW sea grape extract for 14 days. Group P2 was induced by 30mg/Kg BW indomethacin for 7 days followed by administration of 2g/100g BW sea grape extract for 14 days. On the 29th day, rats were terminated, gastric and duodenal were isolated then the fluid pH was measured. One-way Anova test obtained p = 0,023. Post hoc test pH Gaster significantly different between group K (-) and K (+) (p= 0,005) and between group K (-) with P2 (p= 0,020). While in group K (+) with P1 and P2 there was no significant difference in pH. Post hoc test of pH duodenum showed no differences in all group. The administration of sea grape extract did not show a differences of the gastric and duodenal pH significantly between rats induced by indomethacin.

Page 28 of 39 | Total Record : 390

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