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Jurnal Ilmiah Kedokteran Wijaya Kusuma
Published by Universitas Wijaya Kusuma Surabaya
ISSN : 19782071     EISSN : 25805967     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health
Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published twice a year. The articles will be published in JIKW only manuscript that has never be published or published in other journal. Writers who will publish the article please follow the JIKW guidelines. The entire management process both admission and review the article is done by online.
Arjuna Subject : -
Articles 390 Documents
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HEREDITAS DAN GENETIKA DALAM PRESTASI OLAHRAGA DITINJAU DARI PERSPEKTIF PERKEMBANGAN MANUSIA Rohman, Ujang
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 2, No 1 (2013): Edisi Mei 2013
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Manusia adalah makhluk hidup yang selalu mengalami perubahan dari waktu ke waktu. Bermula dari proses pembuahan yang terjadi dalam bentuk menyatunya sperma sang ayah dengan sel telur ibu, terbentuklah serangkaian organisme yang kemudian tumbuh menjadi janin. Dari proses inilah yang akan menentukan menjadi manusia yang akan menjalani hidup dengan proses gerak yang terus-menerus dan berkelanjutan. Bagaimanakah peran hereditas dan genetika dalam menghasilkan manusia yang unggul (berprestasi) dalam bidang olahraga perspektif ilmu perkembangan manusia ? Hereditas dan genetika belum dapat mempengaruhi prestasi olahraga, faktor lingkungan yang mempengaruhi prestasi olahraga. Faktor genetika dapat mempengaruhi jenis olahraga yang ditekuni (Gen tanpa faktor varian R577X plasma ACTN3 untuk olahraga sprint/power, dan Varian R577X pada plasma ACTN3 untuk olahraga ketahanan/endurance)
Uji Widal (Widal Test) Sudibya, Akhmad
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Widal Test is one of the application of diagnostic immunology in the diagnosis of typhoid fever. Widal Test must be taught at the school of medicine although some physicians opines that this test is quite obsolete. In real life there are stillmany physicians in developing countries who consider this test as very instrumental in the diagnosis of typhoid fever.
HYMENOLEPIASIS NANA Palgunadi, Bagus Uda
Jurnal Ilmiah Kedokteran Wijaya Kusuma 2009: edisi khusus Desember 2009
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Hymenolepiasis nana is a zoonosis disease caused by infection in adult stage or larvae stage of dwarf tapeworm Hymenolepis nana , that has primarily become a parasite for humans. Human is a main infection source for other human being, even though mouse and mice can also be the infection source of this disease. In its life cycle, Hymenolepis nana doesnt need any intermediate host. The infection doesnt affect on intestinal mucosa , but it may lead to the desquamasi of epithel cell and necrosis in which the parasite attached, causing enteritis in certain severe infection cases. This disease is diagnosed by finding typical type of egg inside the patients feces. Praziquantel is a drug of choice against hymenolepiasis nana. To repress and avoid the infection, we must rise the sanitary awareness in our surroundings at the individual level and for children. Medication treatment for the infected patients is also need to prevent further contamination, and eradication of hospes recervoar as its source of infection, such as mouse and other rodents animals, is recommended as well.
THE POTENCY OF Candida albicans PROTEIN EXTRACT AS BIORESEPTOR ON IMMUNOCENCOR TO DIAGNOSE CANDIDIASIS Masfufatun, Masfufatun; Sudibya, Akhmad; Kumala, Nur
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 2 (2014): edisi Oktober 2014
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

So far, diagnosing on candidiasis has still been limited in standard blood culture. The traditional method of this microbiology culture is less sensitive, many patients with candidasis infection have negative blood culture, and need a long time. This case encourage many researchers to use another alternative methode to diagnose. The purpose of this research is to examine the potency of Candida albicans protein extract as bioreseptor on immunocencor to  detect  Candida albicans and its biofilm in the blood of candidiasis patients. The research method which is used is descriptive with the following steps : (1) isolating enzim from the liquid of digestive gland of snail (Achatina fulica); (2) extraction of protein candida albicans  through  enzimatis and mechanic methods and (3) Analyzing the protein extract as bioreseptor through immunodot assay.The research result shows that the snail enzyme has the protein content 1.35 mg/ml and the specific activity 1.96 unit/mg. This snail enzyme can hydrolyze  the cell wall of Candidia albicans  and, with the help oh sonication, produce extract of planktonic extracel protein (PEP) and biofilm (PEB), extract of planktonic intracell protein (PIP), and biofilm (PIB), with each protein content 1.44; 1.29; 1.29 and 1.21 mg/ml. The characeristic of biofilm intracell protein (PIB) is antigenic on antibody anti-candida (positive control) with giving red spot on immunodot assay. Immunodot assay can distinguish negative control serum (health man) and positive Candidiasis control by using antigen 1 ng/nl and 50nl serum.
The Effect of Anti Masquito Electric Gas that Consist Allethrin That Influence The Weight and Colour of Rats Liver nurmawanti, nurmawanti; Soekanto, Ayly
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 6, No 2 (2017): EDISI SEPTEMBER 2017
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

The aim of this research is to know the influence of anti mosquito electric gas that consisted Allethrin to the weight and colour of the rats liver. This research used an experimental method with the post test only  control group design.  The subject of this research is male rats weight of 150 grams each and total there was 24 rats that were divided to 4 groups. The first one, the  control groups (PO) was not given any of the gas, the second one, group 1 (P1) was given the gas for 4 hours everday, the third one, group  2 (P2), was given for 6 hours and last, group 3  (P3) was given 8 hours everyday. After later, on  30 Th day, the rats were terminated and being put in a surgery to remove their liver. This data was analyzed using SPPS for windows version 16. To see the differences in weight between the groups, it was analyzed using anova, and  to obtain the discoloration of the rats liver was analyzed using Kruskal Wallis Test. From the statistic tests, it show that there is significant difference in weight and color of liver in the group that α ≤ 0,05. According Anova Test, it shows that there is a significant difference α = 0,034 and from Kruskal Wallis test α = 0,013. In the conclusion anti mosquito electric gas that consist Allethrin affects the weight and the color of rats liver.
DESCRIPTION OF OSTEOPOROSIS RISK BASED NUTRITION STATUS IN ELDERLY AND CALCIUM INTAKE IN PUSKESMAS SIDOSERMO SURABAYA 2015 Prabawani, Yuni
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 4, No 2 (2015): Edisi Desember 2015
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Background. The number of elderly in Indonesia in 2011 about 24 million people, or nearly 10% of the population. Experts projected that by 2020, life expectancy was 71.7 years with the elderly into estimates of the number of elderly 28.8 million people (11.34%). An increase in the number of elderly will cause problems in the elderly, especially the problem of degenerative diseases, one of them is osteoporosis. Prevalence rate of osteoporosis is higher so the need for vigilance. Causes Osteoporosis is multifactoral, such as unhealthy lifestyle and not exercising regularly, as well as the prevention of osteoporosis knowledge is lacking. The occurrence of Osteoporosis caused by lack consumption of calcium in Indonesian society. The purpose of this research was to describe the risk of osteoporosis by nutritional status and calcium intake in the elderly in health centers Sidosermo Surabaya 2015. Methodology This study is a descriptive study with cross sectional approach. A total of 28 elderly people (samples) with a total sampling method. Body weight was measured by digital scale, height was measured by microtoise staturemeter, Osteoporosis was assessed through the measurement of bone density by using Hologic Sahara Densitometry Quantitative Ultrasound (QUS) in the calcaneus bone, which is classified into three is normal, mild risk and high risk. Results: A total of 7 people (25%) had osteoporosis, 21 people had osteopenia (75%). Twelve have a normal body mass index, and 16 had abnormal body mass index. Calcium intake in 8 people (28,6%) had enough calcium intake and 20 people (71,4 %) had low calcium intake.Conclusion: The incidence of osteoporosis in the Health Center Sidosermo Surabaya occurred in elderly with abnormal BMI and inadequate calcium intake.
REACTION BIOMARKER MONOCLONAL FRAGMENTATION OF COLLAGEN TYPE IV WITH BLOOD SERUM ACUTE MYOCARDIAL INFARCTION PATIENT RELATED INFECTION Muliartha, Ketut
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 1, No 1 (2012): Edisi Juli 2012
Publisher : Universitas Wijaya Kusuma Surabaya

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Penelitian ini bertujuan untuk mendeteksi penyakit jantung akut myocardial infark dengan menggunakan biomarker antibodi monoclonal fragmentasi kolagen tipe IV. Rupture plak aterosklerosis adalah terjadi karena degradasi kolagen tipe IV. Perviromonas gingivalis adalah salah satu faktor resiko yang terpenting untuk terjadinya akut myocard infark (AMI). Rancangan penelitian ini adalah ekperimental invitro dengan deksriptif cross sectional. Sampel penelitian adalah empat orang sehat (n=4) serta 12 penderita AMI (n=12). Untuk melihat ekpresi enzim MMP-9 dan fragmentasi kolagen tipe IV, kami menggunakan teknik western bloting. Untuk mengisolasi sel limfosit, kami mengimunisasi mencit dengan antigen fragmentasi kolagen tipe IV disertai dengan adjuvant. Selanjutnya dilakukan fusi antara sel limfosit dengan sel myeloma sehingga terbentuk hibridoma dan diuji dengan western bloting serta ELISA teknik. Kemudian dilakukan seleksi klon. Selanjutnya dilakukan insersi pada intra peritoneal sehingga terbentuk ascites. Hasil penelitian ini menunjukkan bahwa MMP-9 muncul pada 92 kDa dan fragmentasi kolagen tipe IV dengan band 60 – 80 kDa. Untuk menguji reaksi monoklonal antibodi fragmentasi kolagen tipe IV dilakukan uji 12 sampel penderita AMI. Hasilnya semua sampel AMI positif. Kesimpulan menunjukkan bahwa biomarker monoklonal antibodi fragmentasi kolagen tipe IV ternyata bereaksi positif pada penderita AMI.
THE ROLE OF FUMES EXPOSURE FROM ELECTRIC MOSQUITO REPELLENT CONTAINED ALLETHRIN AGAINST WEIGHT AND COLOUR OF THE RAT’S LUNGS Hayu, Tri Pangesti; Soekanto, Ayly
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 5, No 1 (2016): Edisi Maret 2016
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Lungs as place where the gases exchange inside the body is related to enviroment sorrounding. Usage of electric mosquito repellent that contained allethrin on certain period can inflict lung’s abnormalities.The aim to this research is to find the effect of fumes exposure from the electric mosquito repellent that contained allethrin to weight and colour of rat’s lungs. The research was experimental laboratory. 24 male rats strain Wistar that devided into 4 groups, which were group 1 control (P0) without exposure, group 2 (P1) exposed 4 hours a day, group 3 (P2) exposed 6 hours a day and group 4 (P3) exposed 8 hours a day. In 30 th day, the rats terminated in the order to taken their lungs organ by operation. The purpose of taken the lungs was analyzed lung’s weight and alteration of its colour. The acquired data process by Anova test for weight analysis, and Kruskal Wallis test for colour change analysis, respectively with significant value (α < 0,05). The result of anova test is (α = 0.004) and kruskal wallis test is (α = 0,001), that to mean there are significan differentiation in group. Conclusion of this research : there was an effects of fumes exposure of electric mosquito repellent that contain allethrin against the weight and colour of the rat’s lungs. That effect on the lungs occour because collaps of the alveolus or lungs.
EFFECT OF INTAKING HIGH-FAT DIET ON WHITE RAT’S (Rattus norvegicus) BLOOD LIPID PROFILE Harsa, Made Subawa
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 1 (2014): Edisi Maret 2014
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Obesity and metabolic syndrom are characterized by dislipidemia. One of methods that is performed to increase body fat contents is by intaking of high-fat diet. The purpose of this study was to demonstrate the effect of a dietary intake of high-fat on the lipid profile (total cholesterol, HDL, LDL, and triacylglycerol) in white rat (Rattus norvegicus). This research was tested on 30 white rats that were divided into 2 randomized groups, and were treated for 4 weeks. Group 1 (K1) : was treated with standard diet, (K2) : with standard and high-fat diet. The results showed that intaking high-fat diet increases the total cholesterol content, triacylglycerol, LDL cholesterol, and decreases HDL cholesterol content.
Prednisone USE IN PATIENTS WITH ASTHMA BRONKHIALE linked IgE AND IgG LEVELS PATIENTS Tjandra, Lusiani
Jurnal Ilmiah Kedokteran Wijaya Kusuma 2009: edisi khusus Desember 2009
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Background: There’s been reported that the use of prednisone increase the occurrence of disease caused by viruses. And so, this study was done to find out the IgG and IgE status in asthmatic bronchial patients who used prednisone.Methods: The immunodiagnostic test applied was the precipitation test.Results: Showed that the average of IgG in asthmatic bronchial patients who used prednisone is 1332,09 mg/dl, less than the average IgG in patients who did not use prednisone. The average of IgE in asthmatic bronchial patients who used prednisone is 4224,0.10-5mg/dl, less than the average of IgE in patients who did not use prednisone. The use of prednisone as a therapy for asthma bronchiale does lower the rate of IgG but that rate is still within the range of normal IgG rate in human body (639 – 1349 mg/dl).Conclusions: So, the use of prednisone can’t make human suffers from diseases cause by viruses just because the use of prednison as a therapy in asthma bronchiale.

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