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Sunny Wangko
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INDONESIA
e-CliniC
ISSN : 23375949     EISSN : -     DOI : -
Core Subject : Health,
Jurnal e-CliniC (eCl) diterbitkan oleh Perhimpunan Ahli Anatomi Indonesia bekerja sama dengan Fakultas Kedokteran Universitas Sam Ratulangi Manado. Jurnal ini diterbitkan 3 (tiga) kali setahun (Maret, Juli, dan November). Sejak tahun 2016 Jurnal e-CliniC diterbitkan 2 (dua) kali setahun (Juni dan Desember). Jurnal e-CliniC memuat artikel penelitian, telaah ilmiah, dan laporan kasus di bidang ilmu kedokteran klinik.
Articles 1,074 Documents
Manfaat Proloterapi pada Osteoartritis Lutut Deeng, Gracia V. Y.; Sekeon, Sekplin A. S.; Warouw, Finny
e-CliniC Vol 9, No 1 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i1.32479

Abstract

Abstract: Osteoarthritis (OA) is calcification of the joint associated with severe painful sensation caused by joint instability. This joint instability is affected by destruction of cartilage that protects the bones. Osteoarthritis can be caused by various factors such as age, genetic as well as vigorous exercise or activity. As the cartilage destruction progresses, the unprotected bone will rub on the other bone in the joint which can lead to osteoarthritis. Management of OA consists of a variety of treatments, such as pharmacological, non-pharmacological, non-pharmacotherapy, and surgery treatments. Due to the development of science and technology, various modalities have emerged that can support the treatment of OA inter alia prolotherapy. Prolotherapy or regenerative injection could influence the recovery of the destructed area directly and relief the painful sensation through the actions of inflammatory cells, macrophages, immune cells, and cytokines, therefore, the improvement of the destructed areas could occur faster. It was reported that knee osteoarthritis could be treated with prolotherapy successfully. In conclusion, since prolotherapy influences the body to repair the destructed areas, hence it could be used as the new osteoarthritis treatment, especially knee osteoarthritis.Keywords: prolotherapy, knee osteoarthritis, chronic pain Abstrak: Osteoartritis (OA) merupakan pengapuran sendi yang disertai nyeri hebat, disebabkan oleh karena adanya ketidakstabilan sendi yang dipengaruhi oleh rusaknya tulang rawan yang berperan untuk melindungi tulang. Osteoartritis dapat disebabkan oleh berbagai faktor seperti usia, jenis kelamin, genetik, aktivitas maupun olahraga berat. Saat tulang rawan rusak, maka tulang yang tidak dilindungi dapat saling bersinggungan di sendi sehingga sendi hancur dan berujung pada OA. Pengobatan untuk OA terdiri dari beragam pengobatan baik farmakologi, non-farmakologi, non-farmakoterapi, maupun tindakan operasi. Seiring berjalannya perkembangan ilmu pengetahuan dan teknologi, maka muncul berbagai modalitas yang dapat menunjang pengobatan OA, antara lain proloterapi. Proloterapi atau injeksi regeneratif memengaruhi dan memberi dampak penyembuhan secara langsung pada area yang mengalami cedera maupun nyeri melalui kerja sel-sel radang, makrofag, sel-sel imun, dan sitokin sehingga dapat bekerja lebih cepat untuk perbaikan daerah yang cedera. Telah dilaporkan hasil bermakna dalam peng-gunaan proloterapi pada osteoartritis lutut. Simpulan penelitian ini ialah proloterapi merangsang tubuh untuk memperbaiki daerah yang cedera sehingga merupakan solusi terbaik yang dibutuhkan dalam pengobatan OA dewasa ini terutama pada OA lutut.Kata kunci: proloterapi, osteoartritis lutut, nyeri kronik
Profil Penderita Morbus Hansen (MH) di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado Periode Januari – Desember 2013 Desrina, Andiswati; Kapantow, Grace M.; Kandou, Renate T.
e-CliniC Vol 8, No 2 (2020): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v8i2.30132

Abstract

Abstract: Morbus Hansen (MH) is still a public, social, and rehabilitation problems due to the physical disability resulted from delayed or inadequate treatment. This study was aimed to obtain the profile of MH patients at the Dermatovenerology clinic, Prof. Dr. R. D. Kandou Hospital Manado in the period of January to December 2013. This was a descriptive and retrospective study. The results showed that there were 98 MH patients consisting of 69 males (70.4%) and 29 females (29,6%). The majority of patients were 25-44 years old (47.0%) with multibacillary type (93.9%). Most patients did not show lepra reaction (67.3%); erythema nodosum leprosum (ENL) reaction was found in 29.6% of patients, and reversal reaction in 3.1% of patients. As many of 29.6% had been treated with multidrug therapy (MDT), and 10.2% did not, meanwhile, 60,2% of patients did not have any data of treatment. In conclusion, the majority of MH patients at the Dermatovenerology clinic, Prof. Dr. R. D. Kandou Hospital Manado in the period of January to December 2013 were males, aged 25-44 years, had multibacillary type with ENL reaction, and had been treated with MDT.Keywords: Morbus Hansen profile Abstrak: Morbus Hansen (MH) masih merupakan masalah kesehatan, sosial, dan rehabilitasi oleh karena kecacatan fisik yang terjadi akibat pengobatan yang terlambat atau tidak memadai. Penelitian ini bertujuan untuk mengetahui profil penderita MH di Poliklinik Kulit dan Kelamin RSUP Prof. R. D Kandou Manado periode Januari-Desember 2013. Jenis penelitian ialah deskrip-tif retrospektif. Hasil penelitian mendapatkan 98 penderita MH (6,72%) dari total 1457 pasien, terdiri dari 69 laki-laki (70,4%) dan 29 perempuan (29,6%). Mayoritas penderita berada pada rentang usia 25-44 tahun (47,0%) dengan tipe MH multibasiler (93,9%). Pada sebagian besar pen-derita tidak didapatkan reaksi lepra (67,3%); reaksi erythema nodosum leprosum (ENL) didapatkan pada 29,6% penderita dan reaksi reversal pada 3,1% penderita. Mengenai riwayat pengobatan, sebesar 29,6% telah mendapat pengobatan multidrug therapy (MDT) sebelumnya dan 10,2% belum pernah mendapatkan pengobatan MDT, namun sebesar 60,2% penderita tidak memiliki data pengobatan. Simpulan penelitian ini ialah mayoritas penderita MH di Poliklinik Kulit dan Kelamin RSUP Prof. R. D Kandou Manado periode Januari-Desember 2013 berjenis kelamin laki-laki, usia 25-44 tahun, tipe MH multibasiler, dengan reaksi ENL, dan pernah mendapat pengobatan MDT.Kata kunci: profil Morbus Hansen
Faktor Risiko yang Berhubungan dengan Kejadian Kelainan Bawaan pada Neonatus Matthew, Febriano; Wilar, Rocky; Umboh, Adrian
e-CliniC Vol 9, No 1 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i1.32306

Abstract

Abstract Congenital abnormalities are one of the main causes of infant mortality worldwide. Their symptoms vary from mild to severe. This study was aimed to determine the risk factors associated with the incidence of congenital abnormalities. This was a literature review study. The results obtained 10 articles that discussed about the risk factors of congenital abnormalities. The incidence of congenital abnormalities was more common in males. The most common factor was the maternal age of 20+ years Especially in Indonesia, there was no significant data about the risk factors related to the incidence of congenital abnormalities, however, two journals from Indonesia showed an increased incidence of congenital abnormalities in women infected during pregnancy. In addition, there were other risk factors found only in one to two journals, such as exposure to cigarettes, consumption of drugs or narcotics, and family history of previous congenital disorders. The review also covered several congenital disorders classified in organ systems dominated by the cardiovascular system. In conclusion, the risk factors associated with congenital abnormalities are maternal age, multiparity, history of abortion, congenital abnormalities in previous pregnancies, gestational diabetes, exposure to cigarette smoke, consumption of alcohol, consumption of drugs, not taking folic acid, family history of congenital abnormalities, consanguinity, and low socioeconomic statusKeywords: risk factor, birth defect, congenital anomalies, neonates                                                                         Abstrak Kelainan kongenital merupakan salah satu penyebab utama kematian bayi di dunia dengan gejala bervariasi dari ringan hingga berat. Penelitian ini bertujuan untuk mengetahui faktor risiko yang berhubungan dengan kejadian kelainan kongenital. Jenis penelitian ialah literature review. Hasil penelitian mendapatkan 10 artikel mengenai faktor risiko kejadian kelainan kongenital. Kejadian kelainan kongenital lebih sering terjadi pada jenis kelamin laki-laki. Faktor risiko yang paling sering ialah usia ibu saat hamil mulai 20 tahun hingga lebih. Khusus di Indonesia belum ada data bermakna yang menunjukkan faktor risiko yang berhubungan dengan kejadian kelainan kongenital, namun dua artikel dari Indonesia menunjukkan peningkatan kejadian kelainan kongenital pada ibu yang terinfeksi saat hamil. Faktor risiko lainnya yang hanya didapatkan pada satu hingga dua jurnal saja seperti, paparan rokok, konsumsi obat maupun narkoba, serta riwayat keluarga yang pernah mengalami kejadian kelainan bawaan sebelumnya. Hasil kajian juga mendapatkan beberapa diagnosis penyakit kelaianan kongenital yang di golongkan dalam sistem organ, didominasi oleh sistem kardiovaskular. Simpulan penelitian ini ialah faktor risiko yang berhubungan dengan kelainan kongenital ialah usia ibu, multiparitas, riwayat abortus, kelainan ba kongenital waan pada kehamilan sebelumnya, diabetes gestasional, paparan asap rokok, konsumsi alkohol, konsumsi obat-obatan, tidak mengonsumsi asam folat, riwayat keluarga mengalami kelainan kongenital, adanya hubungan darah antara ayah dan ibu, dan status sosioekonomi rendahKata kunci: faktor resiko, kelainan kongenital, neonatus
Faktor Risiko Tuberkulosis pada Anak Wijaya, Muhammad S. D.; Mantik, Max F. J.; Rampengan, Novie H.
e-CliniC Vol 9, No 1 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i1.32117

Abstract

Abstract: Tuberculosis (TB) is still one of the biggest health problems worldwide due to high morbidity and mortality rates. Moreover, Indonesia has the third largest TB cases in the world after India and China. This study was aimed to evaluate the risk factors of TB in children. This was a literature review study using three databases, namely Google Scholar, ClinicalKey, and PubMed. The results showed that after being selected by inclusion and exclusion criteria, there were 10 literatures in this study consisting of 2 case control studies, 4 cross sectional studies, 1 difference test, 1 meta-analysis, 1 case report, and 1 cohort study. The 10 literatures reviewed factors or characteristics of age, sex, history of BCG immunization, malnutrition, history of contact with person suffering from TB, exposure to cigarette smoke, occupant density, and poverty. Risk factors obtained from the review were young age (0-5 years), male sex, malnutrition, history of contact, and poverty. The other risk factors specifically history of BCG immunization, exposure to cigarette smoke, and occupant density were still contradicting among literatures. In conclusion, the most dominant risk factor of TB in children is history of contact with person suffering from TB. Keywords: risk factors, tuberculosis, children.  Abstrak: Penyakit tuberkulosis (TB) masih menjadi salah satu masalah kesehatan terbesar di dunia dikarenakan angka morbiditas dan mortalitas yang tinggi. selain itu Indonesia merupakan negara dengan kasus TB terbesar ketiga di dunia setelah India dan Tiongkok. Penelitian ini bertujuan untuk mengevaluasi faktor risiko tuberkulosis pada anak. Jenis penelitian ialah literature review dengan menggunakan tiga database, yakni Google Scholar, ClinicalKey, dan PubMed. Hasil penelitian mendapatkan bahwa diseleksi dengan kriteria inklusi dan eksklusi, didapatkan 10 literatur yang terdiri dari 2 case control study, 4 cross sectional study, 1 uji beda, 1 meta-analysis, 1 case report, dan 1 cohort study. Sepuluh literatur ini mengulas tentang pengaruh faktor atau karakteristik terhadap TB ada anak, yaitu: usia, jenis kelamin, riwayat imunisasi BCG, malnutrisi, riwayat kontak dengan pengidap TB, asap rokok, kepadatan hunian, dan kemiskinan. Faktor-faktor risiko yang diperoleh ialah usia muda (0-5 tahun), jenis kelamin laki-laki, malnutrisi, riwayat kontak, dan kemiskinan dapat memengaruhi kejadian TB pada anak. Faktor-faktor risiko lainnya yakni riwayat imunisasi BCG, paparan asap rokok, dan kepadatan hunian masih kontradiktif antar literatur. Simpulan penelitian ini ialah faktor risiko yang paling dominan menyebabkan penyakit TB pada anak ialah riwayat kontak.Kata kunci: faktor risiko, tuberculosis pada anak
Nilotinib as the First Line Therapy in Managing Chronic Myelogenous Leukemia Setyawan, Yuswanto
e-CliniC Vol 9, No 2 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i2.32699

Abstract

Abstrak: Leukemia mieloid kronis (chronic myeloid leukemia/CML) adalah penyakit klonal dari sel induk hematopoietik, secara sitogenetik ditandai dengan adanya kromosom Philadelphia (t[9,22][q34;q11]), yang merupakan fusi BCR-ABL1 onkogen. Nilotinib, generasi kedua inhibitor kinase tirosin, merupakan turunan aminopirimidin yang menghambat aktivitas kinase tirosin protein BCR-ABL. Dengan aktivitas penghambatan yang 10-60 kali lebih besar daripada imatinib, pada terapi lini pertama standar untuk CML, nilotinib efektif untuk CML fase kronik dan akselerasi yang resisten terhadap imatinib, namun terapi kombinasi nilotinib dengan agen lainnya masih diperlukan untuk pasien dengan CML krisis blas. Nilotinib aktif terhadap beberapa mutan BCR-ABL yang resisten terhadap imatinib, kecuali mutan T315I. Mutasi spesifik E255K/V, Y253H/F, F359C/V, dan L248V umumnya kurang sensitif terhadap nilotinib. Sebagai terapi lini pertama pada pasien CML fase kronik dengan Ph+ yang baru terdiagnosis, nilotinib menunjukkan CCyR dan MMR yang lebih tinggi serta pengembangan menjadi fase akselerasi/krisis blas serta resiko kematian yang lebih rendah, bila dibandingkan dengan imatinib. Simpulan penelitian ini ialah nilotinib lebih unggul dibandingkan dengan imatinib sebagai terapi lini pertama pada pasien CML fase kronik dengan Ph+ yang baru terdiagnosis,Kata kunci: chronic myeloid leukemia (CML), nilotinib, imatinib, terapi lini pertama  Abstract: Chronic myeloid leukemia (CML) is a clonal disease of the hematopoietic stem cells, cytogenetically characterized by Philadelphia chromosome (t[9,22][q34;q11]) leading to the fusion of BCR-ABL1 oncogene. Nilotinib, the second-generation tyrosine kinase inhibitor (TKI), is an aminopyrimidine derivative that inhibits the tyrosine kinase activity of the chimeric protein BCR-ABL. Its inhibitory activity is 10-60 times that of imatinib, therefore, as the standard first-line therapy for CML, nilotinib is effective in the case of CML-CP and CML-AP with imatinib resistant or intolerant. Albeit, novel approaches with nilotinib-based combinations are required for patients in CML-BP. Nilotinib is active against several imatinib-resistant BCR-ABL mutants with the exception of T315I. Specific mutations that are less sensitive to nilotinib include E255K/V, Y253H/F, F359C/V, and L248V. As the first-line therapy of patients with newly diagnosed Ph+ CML-CP, nilotinib has higher rates of CCyR and MMR, lower rates of progression to AP or BC, and lower risk of CML related death when compared with imatinib. In conclusion, nilotinib is superior to imatinib as the the first-line therapeutic option in newly diagnosed Ph+ CML-CP patients.Keywords: chronic myeloid leukemia (CML), nilotinib, imatinib, first line therapy
Gambaran Premenstrual Syndrome pada Remaja Periode Akhir di Fakultas Kedokteran Universitas Sam Ratulangi Lumingkewas, Charisma; Suparman, Eddy; Mongan, Suzanna P.
e-CliniC Vol 9, No 1 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.9.1.2021.31855

Abstract

Abstract: Premenstrual syndrome (PMS) is the most common untreated disorder and a public health problem among women of reproductive age, which adversely affects mental well-being, quality of life, and academic achievement. This study was aimed to determine the premenstrual syndrome signs and symptoms most experienced by late adolescents. This was a descriptive and survey study using questionnaire distributed through google form to 142 female students from first and third semester of Faculty of Medicine Sam Ratulangi University academic year 2020/2021. The results showed that the most common type of PMS symptoms was psychological symptoms found in 136 respondents (95.8%); the most common behavioral symptom was fatigue in 93 respondents (65.5%), the most common physical symptom was acne in 122 respondents (85.9%); and the most psychological symptom was mood swing in 125 respondents (88%). In conclusion, the most common premenstrual syndrome symptom found in late adolescent at the Faculty of Medicine Sam Ratulangi University according to the type of symptom was psychological symptom.Keywords: premenstrual syndrome, adolescent Abstrak: Premenstrual syndrome (PMS) merupakan kelainan umum yang tidak diobati dan masalah kesehatan masyarakat di kalangan wanita usia reproduksi, yang berdampak buruk pada kesejahteraan mental, kualitas hidup dan prestasi akademik. Penelitian ini bertujuan untuk mengetahui tanda dan gejala PMS yang paling banyak dialami remaja periode akhir. Penelitian ini menggunakan metode survei deskriptif dengan alat kuesioner yang dibagikan melalui google form pada 142 mahasiswi semester 1 dan 3 Fakultas Kedokteran Universitas Sam Ratulangi tahun ajaran 2020/2021. Hasil penelitian mendapatkan jenis gejala PMS yang paling banyak dialami ialah gejala psikologis pada 136 responden (95,8%), gejala perilaku yang paling banyak dialami ialah kelelahan pada 93 responden (65,5%), gejala fisik yang paling banyak dialami ialah muncul jerawat pada 122 responden (85,9), dan gejala psikologis yang paling banyak dialami ialah mood swing pada 125 responden (88%). Simpulan penelitian ini ialah gambaran PMS pada remaja periode akhir di Fakultas Kedokteran Universitas Sam Ratulangi yang paling banyak dialami menurut jenis gejala ialah gejala psikologis.Kata kunci: premenstrual syndrome, remaja 
Terapi Reperfusi pada Infark Miokard dengan ST-Elevasi Bambari, Hana A; Panda, Agnes L; Joseph, Victor F.F.
e-CliniC Vol 9, No 2 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v9i2.32850

Abstract

Abstract: Myocardial infarction is classified into ST-segment elevation myocardial infarction (STEMI) and Non-ST-segment elevation myocardial infarction (NSTEMI). STEMI patient is considered for a reperfusion therapy, consisting of percutaneous coronary intervention (PCI), fibrinolytic therapy, and coronary artery bypass grafting (CABG). This study was aimed to determine the effectiveness of reperfusion therapy in STEMI patients. This was a literature review study. The results described the effectiveness of reperfusion therapy in terms of the time action, as follows: effective PCI if <120 minutes, fibrinolytic therapy <90 minutes, and CABG within four to 30 days after angiography. In case of revascularization with PCI there was a decrease in mortality and complications of reinfarction, major bleeding, and stroke. There was a reduction in complications of cardiogenic shock with fibrinolytic therapy when given within the first 60 minutes of symptom onset. Fibrin-spesific fibrinolytics (accelerated infusion alteplase, tenecplase, and reteplase) were the most effective regimen associated with reduced mortality. CABG procedure is recommended in coronary anatomical conditions that was not suitable for PCI and several other indications; although the complications were high but the survival of 30 days and one year was very good. In conclusion, PCI is the first line choice and effective if performed less than the first 120 minutes. Fibrinolytics are effective if they are administered during the first 60 minutes in case the PCI is not performed. Moreover, CABG is recommended in anatomical coronary condition that is not suitable for PCI and other indications.Keywords: reperfusion therapy, acute myocardial infarction, STEMI  Abstrak: Infark miokard diklasifikasikan atas ST-segment elevation myocardial infarction (STEMI) dan Non-ST-segment elevation myocardial infarction (NSTEMI). Pada pasien STEMI diper-timbangkan untuk dilakukan terapi reperfusi yang terdiri dari percutaneous coronary intervention (PCI), terapi fibribolitik, dan coronary artery bypass grafting (CABG). Penelitian ini bertujuan untuk mengetahui efektivitas terapi reperfusi pada pasien STEMI. Jenis penelitian ialah literature review. Hasil penelitian ini menjelaskan efektivitas terapi reperfusi ditinjau dari waktu tindakan. Tindakan PCI efektif dilakukan <120 menit, terapi fibrinolitik <90 menit, dan CABG dalam empat hingga 30 hari setelah angiografi. Pada kasus revaskularisasi dengan tindakan PCI terdapat penurunan mortalitas dan komplikasi reinfark, perdarahan mayor, dan stroke. Terdapat penurunan komplikasi syok kardiogenik pada terapi fibrinolitik bila diberikan dalam 60 menit pertama setelah onset gejala. Fibrin-spesific fibrinolytics (accelerated infusion alteplase, tenecplase, dan reteplase) merupakan regimen yang paling efektif dikaitkan dengan penurunan mortalitas. Tindakan CABG direko-mendasikan pada kondisi anatomi koroner yang tidak sesuai untuk PCI dan beberapa indikasi lain; meskipun komplikasi tinggi namun kelangsungan hidup 30 hari dan satu tahun sangat baik. Simpulan penelitian ini ialah tindakan PCI merupakan pilihan lini pertama dan efektif diberikan dalam waktu <120 menit. Fibrinolitik efektif diberikan dalam 60 menit pertama bila PCI tidak dapat dilakukan sedangkan tindakan CABG direkomendasikan pada kondisi anatomi koroner yang tidak sesuai untuk PCI dan beberapa indikasi lain.Kata kunci: terapi reperfusi, infark miokard akut, STEMI
Hubungan Pola Konsumsi Minuman Berkafein dengan Fungsi Kognitif pada Lansia di GKJ Gondokusuman Yogyakarta Putra, Dewa K.; Samodra, Yoseph L.; Nugroho, Daniel C. A.
e-CliniC Vol 8, No 2 (2020): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.8.2.2020.31432

Abstract

Abstract: Elderly population which continues to increase in number every year causes various social, economic, and health problems inter alia cognitive dysfunction. One of the efforts that can prevent and slow down the decline in cognitive function is consuming caffeinated beverages. This study was aimed to evaluate the relationship between the pattern of caffeinated beverage consumption and cognitive function among the elderly at GKJ Gondokusuman in Yogyakarta. This was an analytical observational study with a cross-sectional design. We used the modified Food Frequency Questionnaire (FFQ) to measure the consumption patterns of caffeinated beverage meanwhile the cognitive function was measured by using the Mini Mental State Examination (MMSE) and the Clock Drawing Test (CDT). Sample size was determined by using the total sampling method. There were 54 samples of elderly population. Data were analyzed by using the Spearman correlation test which obtained (p=0.023; r=-0.309) for the relationship between caffeinated beverage consumption pattern and cognitive function measured with the MMSE, and (p=0.075; r=0.244) for the relationship between caffeinated beverage consumption pattern and cognitive function measured with the the CDT. In conclusion, there was a significant relationship between caffeinated beverage consumption pattern and cognitive function measured with the MMSE, however, there was no significant relationship between caffeinated beverage consumption pattern and cognitive function measured with the the CDT.Keywords: caffeinated beverage consumption patterns, cognitive function, elderlyAbstrak: Populasi lanjut usia (lansia) yang terus mengalami peningkatan setiap tahunnya menimbulkan berbagai masalah sosial, ekonomi, dan kesehatan, antara lain gangguan fungsi kognitif. Salah satu upaya untuk mencegah dan memperlambat penurunan fungsi kognitif ialah dengan minuman yang mengandung kafein. Penelitian ini bertujuan untuk mengetahui adanya hubungan pola konsumsi minuman berkafein dengan fungsi kognitif lansia di GKJ Gondo-kusuman. Jenis penellitian ialah observasional analitik dan desain potong lintang. Pola konsumsi minuman berkafein diukur dengan Food Frequency Questionnaire (FFQ) yang telah dimodifikasi, sedangkan fungsi kognitif diukur dengan Mini Mental (MMSE) dan Clock Drawing Test (CDT). Penghitungan besar sampel dengan metode total sampling mendapatkan 54 sampel dari populasi, yaitu lansia di GKJ Gondokusuman. Hasil analisis data menggunakan uji Spearman terhadap hubungan antara pola konsumsi minuman berkafein dengan fungsi kognitif yang diukur dengan MMSE mendapatkan (p=0,023; r=-0,309) sedangkan dengan fungsi kognitif yang diukur dengan kuisioner CDT mendapatkan (p=0,075; r 0,244). Simpulan penelitian ini ialah terdapat hubungan bermakna antara pola konsumsi minuman berkafein dengan fungsi kognitif lansia yang dinilai menggunakan MMSE, namun tidak terdapat hubungan bermakna dengan fungsi kognitif lansia yang dinilai menggunakan CDT.Kata kunci: pola konsumsi minuman berkafein, fungsi kognitif, lansia
Penanganan Stroke Iskemik Akut di Masa Pandemi COVID-19 Lengkong, Erlika; Warouw, Finny; Kembuan, Mieke A. H. N.
e-CliniC Vol 9, No 1 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.9.1.2021.32421

Abstract

Abstract: When the pandemic corona virus disease (COVID-19) occurs, emergency services and hospitals are finally disrupted. One of the medical emergencies which can cause death and disability as well as other problems if being ignored, especially in productive age patients is stroke. This study was aimed to obtain the management of ischemic stroke during COVID-19 pandemic. This was a literature review study using three databases, namely Clinical Key, PubMed and Google Scholar. The keywords used in data search were acute AND stroke AND pandemic. The results showed that the treatment of acute ischemic stroke during COVID-19 pandemic consisted of three stages, namely pre-hospitalization (public education, contacting medical assistance, use of personal protective equipment, pre-notification), hospitalization (emergency room, imaging room, neuroradiology unit, ICU and IMCU), and post hospitalali-zation (integrated team approach). In conclusion, the management of acute ischemic stroke during COVID-19 pandemic begins before the medical personnel take action until the action is carried out. The main things in the management of acute ischemic stroke during COVID-19 pandemic are handling fast and precisely, using adequate personal protective equipment (PPE), and using communication tools or long-distance medical care (telemedicine).Keywords: acute ischemic stroke, COVID-19, pandemic Abstrak: Saat terjadi pandemi corona virus disease (COVID-19), layanan kegawatdaruratan dan rumah sakit megalami perubahan. Salah satu kasus kegawatdaruratan medik yang menjadi penyebab kematian dan kecacatan serta dapat menimbulkan masalah lainnya jika diabaikan terutama pada pasien usia produktif ialah stroke. Penelitian ini bertujuan untuk mengetahui penanganan stroke pada masa pandemic COVID-19. Jenis penelitian ialah literature review yang menggunakan tiga database yaitu Clinikal key, PubMed dan Google Scholar. Kata kunci yang digunakan dalam pencarian data ialah acute AND stroke AND pandemic. Hasil penelitian mendapatkan penanganan stroke iskemik akut di masa pandemi COVID-19 terdiri dari 3 tahapan yakni prahospitalisasi (edukasi masyarakat, menghubungi bantuan medis, penggunaan alat pelindung diri, pranotifikasi rumah sakit), hospitalisasi (ruang gawat darurat, ruang pencitraan, unit neuroradiologi, ICU dan IMCU), dan pasca hospitalisasi (pendekatan tim terpadu). Simpulan penelitian ini ialah penanganan stroke iskemik akut di masa pandemi COVID-19 dimulai dari sebelum tenaga medis melakukan tindakan sampai setelah tindakan dilaksanakan. Hal utama dalam penanganan stroke iskemik akut di masa pandemi COVID-19 ialah penanganan yang cepat dan tepat, penggunaan alat pelindung diri (APD) yang memadai, dan pemanfaatan alat komunikasi atau perawatan medis jarak jauh.Kata kunci: stroke iskemik akut, pandemi, COVID-19
Gambaran Pasien Stroke Iskemik Akut dengan COVID-19 yang Masuk Ruang Perawatan Intensif Thambas, Anastasia T.; Lalenoh, Diana Ch.; Kambey, Barry I.
e-CliniC Vol 9, No 1 (2021): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.9.1.2021.32302

Abstract

Abstract: Acute ischemic stroke (AIS) has been reported in patients with coronavirus disease 2019 (COVID-19). The cause of AIS in COVID-19 patients has not been fully understood, but COVID-19 is known to cause hypercoagulation characterized by increased d-dimer levels, and cytokine storms.  Some AIS patients with COVID-19 require intensive care. This study was aimed to determine the description of AIS patients with COVID-19 admitted to the intensive care unit. This was a literature review study using three databases, as follows: Pubmed, ClinicalKey, and Science Direct. The keywords used were acute ischemic stroke AND COVID-19 AND intensive care unit. The results showed that after being selected based on inclusion and exclusion criteria, 10 literatures were obtained. There were 20 subjects and most were female (55%) and age group of 60-69 years old (35%). The most common cardiovascular risk factor was hypertension (80%, n=10). There were some increases in the levels of LDH, CRP, d-dimer, ferritinin, and fibrinogen. On radiological examination performed, there were cases with bilateral pulmonary infiltrate (33%) and ground-glass opacities (67%) (n = 6). In conclusion, the characteristics of AIS patients with COVID-19 admitted to the intensive care room were mostly female, age group 60-69 years, had cardiovascular risk factors for hypertension, had elevated levels of LDH, CRP, d-dimer, ferritinin, and fibrinogen, and had ground-glass opacity on radiological imaging.Keywords: acute ischemic stroke, COVID-19, intensive care unit Abstrak: Stroke iskemik akut telah dilaporkan pada pasien dengan coronavirus disease 2019 (COVID-19). Penyebab stroke iskemik akut pada COVID-19 belum diketahui secara menyeluruh, tetapi COVID-19 dapat menyebabkan kejadian hiperkoagulasi ditandai dengan peningkatan kadar d-dimer serta menyebabkan badai sitokin. Beberapa pasien stroke iskemik akut dengan COVID-19 membutuhkan perawatan di ruang perawatan intensif. Penelitian ini bertujuan untuk mengetahui gambaran pasien stroke iskemik akut dengan COVID-19 yang masuk di ruang perawatan intensif. Jenis penelitian ialah literature review dengan pencarian data menggunakan tiga database yaitu Pubmed, ClinicalKey dan Science Direct dengan kata kunci acute ischemic stroke AND COVID-19 AND intensive care unit. Hasil penelitian mendapatkan 10 literatur dengan jumlah subyek penelitian sebanyak 20 orang, jenis kelamin terbanyak ialah perempuan (55%) dengan kelompok usia terbanyak ialah 60-69 tahun (35%). Faktor risiko kardiovaskular yang paling banyak dimiliki subyek penelitian ialah hipertensi (80%, n=10). Terdapat peningkatan kadar LDH, CRP, d-dimer, ferritinin, dan fibrinogen. Pada pemeriksaan radiologi ditemukan bilateral pulmonary infiltrate (33%) dan ground-glass opacitiy (67%) (n=6). Simpulan penelitian ini ialah karakteristik pasien stroke iskemik akut dengan COVID-19 yang masuk ruang perawatan intensif paling banyak ialah perempuan, usia 60-69 tahun, memiliki faktor risiko kardiovaskular hipertensi, mengalami peningkatan kadar LDH, CRP, d-dimer, ferritinin, fibrinogen, dan ditemukan ground-glass opacitiy pada gambaran radiologi.Kata kunci: Stroke iskemik akut, COVID-19, ruang perawatan intensif

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