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Florentinus Dika Octa Riswanto
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Faculty of Pharmacy, Universitas Sanata Dharma, Indonesia
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Jurnal Farmasi Sains dan Komunitas
Published by Universitas Sanata Dharma
ISSN : 16935683     EISSN : 25277146     DOI : https://doi.org/10.24071/
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community / J Pharm Sci Community) firstly published in 2003, is a peer-reviewed, open access scientific journal that publishes research articles, review articles, as well as short communication in various pharmaceutical fields, including Pharmaceutical Technology and Pharmaceutics, Pharmaceutical Analysis, Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Biology, Community Pharmacy, and Clinical Pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 13 Documents
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Search results for , issue "Vol 21, No 2 (2024)" : 13 Documents clear
Nanoemulgel Formulation of Eleutherine palmifolia Onion Bulb Extract and Its Effectiveness in Wound Healing Faisal, Muhammad; Chabib, Lutfi; Dewi, Melynia Sintha; Gani, Michael Raharja; Dwiastuti, Rini
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 2 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007454

Abstract

Eleutherine palmifolia onion, an indigenous medicinal plant from Borneo, is empirically applied to treat wound healing. The objective of this study is to formulate its extract and assess its in vivo wound healing activity. Eleutherine palmifolia onion was extracted with a 96% ethanol solvent. The extract of the Dayak onion bulb was then formulated into a nanoemulsion by applying the DOE method of 2-level factorial design. Four nanoemulsion formulations were further analyzed to obtain the optimal formulation. The particle size analysis and % transmittance was performed using a particle size analyzer and an ultraviolet-visible spectrophotometer. Furthermore, the data were analyzed using the Minitab 19 application with the DOE factorial design method. The three nanoemulgel formulations containing 2.5, 5.0, and 7.5% extract were further investigated for wound healing efficacy in rats. The duration of wound closure was analyzed using paired t-tests. The best nanoemulsion formulation was made with 22.5 mL of Tween 80 and 2 mL of isopropyl myristate oil. This produced particles that were 12.13 nm in size and a 99.12% transmittance rate. Wound length measurements were taken daily for 15 days. The statistical test results of p0.05 indicate that the nanoemulgel of the extract has significant activity in wound healing. The optimal nanoemulsion formula is formula A, and the effective dose of Dayak onion extract nanoemulgel is 5% and 7.5% concentrations, with a wound healing time of 13 days.
Analysis on the Acceptance of COVID-19 Vaccine Administration for Children in Indonesia Based on the Theory of Planned Behavior Hasymi, Liana Fitriani; Mardiati, Nurul; Kusuma Dewi, Ratih Puspita; Rizal, Rizal; Jayanto, Imam; Nurmansyah, Dian
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 2 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.006160

Abstract

The administration of COVID-19 vaccine in children aims to control the spread of this disease in Indonesia. Parents make the decision whether to vaccinate their children against COVID-19 or not. This study was conducted to analyze parents’ acceptance of the COVID-19 vaccination for children in Indonesia based on the Theory Planned Behavior (TPB). The research design used a cross-sectional survey involving 400 parents of children aged 6-11 years in Indonesia in 34 provinces. Samples were purposively selected based on inclusion criteria: parents are older than 18 years, parents of children aged 6-11 years and live in Indonesia. The exclusion criteria were parents of children who recovered from COVID-19 less than 3 months and children with COVID-19 contraindications. The chi-squared test was conducted to determine the correlation between parents’ acceptance and TPB constructs that include attitudes, subjective norms and behavioral control. A multivariate logistic regression analysis was employed to analyze the TPB construct with the largest contribution on parents’ acceptance of the COVID-19 vaccination. The results showed high acceptance toward COVID-19 vaccination for children aged 6-11 years (98.5%). Positive subjective norms and positive behavioral control also contributed to the parental acceptance of the COVID-19 vaccine for children in Indonesia (p-value = 0.000), in which subjective norms had the largest influence (sig. 0.096 value with Exp B value of 6.203). TPB is a useful framework in developing proper interventions to raise the vaccination acceptance of parents in Indonesia.
Evaluation of Antibiotics Used in Pediatric Outpatients with Acute Respiratory Infection at a Private Hospital in Yogyakarta Kurniasari, Margaretha Wulan; Hartayu, Titien Siwi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 21, No 2 (2024)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007707

Abstract

Ensuring patient safety and optimal health outcomes in the healthcare system requires appropriate and rational use of medicines. One of the prescription issues noted in the pediatric clinic at a private hospital is the high use of antibiotics for acute respiratory infections. This study aimed to improve antibiotics used in outpatient pediatric clinic. This study was a descriptive analysis with a cross-sectional study design, combining quantitative and qualitative methods. The population was all prescriptions in January - March 2023. By using a purposive sampling method, there were 340 prescriptions obtained. The instruments of the study were data collection sheets and in-depth interview guidelines. Data were analyzed using the triangulation method. The antibiotic prescription rate was 64% (n=340). There were patients with Azithromycin and Erythromycin who received antibiotics below the dosing recommendations. Observation of patients’ treatment process showed that prescribers did not always suggest the laboratory examinations. Based on in-depth interviews of prescribers, they prescribed antibiotics based on the patient’s clinical examination. Based on in-depth interviews with the hospital managers, there was a tendency to choose a strategy which was a combination of educational and managerial strategies. The strategies to improve the quality of the antibiotics used include conducting training programs for the prescribers and developing standard treatment guidelines.

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