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Pharmacy Study Program, Faculty of Mathematics and Natural Science, Sam Ratulangi University, Manado, North Sulawesi, Indonesia, 95115
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INDONESIA
PHARMACON
Published by Universitas Sam Ratulangi
ISSN : 23022493     EISSN : 27214923     DOI : 10.35799
Core Subject : Health,
Medicine & Pharmacology
Pharmacon is the journal published by Pharmacy Study Program, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Indonesia (P-ISSN: 2302-2493 E-ISSN: 2721-4923). Pharmacon was established in 2012 and published four times a year. Pharmacon is an open access journal and has been indexed by main indexing Google Scholar, GARUDA, Crossref.
Arjuna Subject : -
Articles 1,131 Documents
 76   77   78   79   80 
IDENTIFIKASI DAN UJI RESISTENSI BAKTERI DARI PLAK GIGI DENGAN AMALGAM DI PUSKESMAS TIKALA BARU TERHADAP ANTIBIOTIK GOLONGAN METRONIDAZOL DAN KUINOLON Fabanyo, Nurhidayanti
PHARMACON Vol 6, No 3 (2017): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.6.2017.16886

Abstract

IDENTIFIKASI DAN UJI RESISTENSI BAKTERI DARI PLAK GIGI DENGAN AMALGAM DI PUSKESMAS TIKALA BARU TERHADAP ANTIBIOTIK GOLONGAN METRONIDAZOL DAN KUINOLON Nurhidayanti fabanyo1), Fatimawali1), gayatri citraningtyas1)1)Program studi farmasi FMIPA UNSRAT Manado, 95115 ABSTRACT            One of the problems about oral and dental health is dental plaque. Plaque is a soft layer formed from a mixture of macrophages, leukocytes, enzymes, inorganic components, extracellular matrix, oral epithelial, food debris and bacteria attached to the surface of the tooth. The aim of this research was to investigate the bacteria isolated from dental plaque of patients with amalgam droplets that were resistant to the antibiotic class of Metronidazole and Quinolone. This research used descriptive explorativ method with dental plaque sample from 3 patients at Tikala Baru Public Health Center for bacterial isolation. The results showed that there were 3 types of bacteria, namely Brucella sp., Staphylococcus sp and Phenylobacterium sp of 15 bacterial isolates. All identified bacteria were resistant to antibiotic metronidazole and sensitive to ciprofloxacin.Keywords: Dental plaque, bacteria, resistant, metronidazole, ciprofloxacin ABSTRAK Salah satu masalah tentang kesehatan mulut dan gigi, yaitu plak gigi. Plak adalah lapisan lembut yang terbentuk dari campuran antara makrofag, leukosit, enzim, komponen anorganik, matriks ekstraseluler, epitel rongga mulut, sisa-sisa makanan serta bakteri yang melekat dipermukaan gigi. Tujuan dari penelitian ini adalah untuk mengidentifikasi bakteri yang diisolasi dari plak gigi pasien dengan tumpatan amalgam yang resisten terhadap antibiotik golongan metronidazol dan kuinolon. Penelitian ini menggunakan metode deskriptif eksploratif dengan sampel plak gigi dari 3 orang pasien di Puskesmas Tikala Baru untuk dilakukan isolasi bakteri. Hasil penelitian menunjukkan terdapat 3 jenis bakteri, yaitu Brucella sp., Staphylococcus sp dan Phenylobacterium sp yang didapat dari 15 isolat bakteri. Semua bakteri yang teridentifikasi telah resisten terhadap antibiotik metronidazol dan sensitif terhadap siprofloxacin. Kata kunci : Plak gigi, bakteri, resisten, metronidazol, siprofloxacin  
EFEKTIVITAS ANTIBAKTERI EKSTRAK BIJI BENGKUANG (Pachyrrhizus erosus) TERHADAP PERTUMBUHAN Streptococcus mutans SECARA IN VITRO Supari, Ian Handry
PHARMACON Vol 5, No 3 (2016): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.5.2016.12935

Abstract

EFEKTIVITAS ANTIBAKTERI EKSTRAK BIJI BENGKUANG (Pachyrrhizus erosus) TERHADAP PERTUMBUHAN Streptococcus mutans SECARA IN VITRO Ian Handry Supari1), Michael A. Leman1), Kustina Zuliari1) 1)Program Studi Pendidikan Dokter Gigi, Fakultas Kedokteran, UNSRAT, Manado, 95115   ABSTRACT Dental caries is an oral health problems that often occurs. Streptococcus mutans is a bacteria main causes of dental caries. Research using natural materials has been carried out. One of the useful plants is the Yam. Yam seed (Pachyrrhizus erosus) contains flavonoids, saponins, tannins, quinones, alkaloids, triterpenoids. This study aims to determine the effectiveness of antibacterial Yam seeds extract on the growth of Streptococcus mutans in vitro. This research was a laboratory experimental with the study design post test only control group design. Testing methods used in this study was modified Kirby-Bauer method using the sinks. MHA media provided as many as five a petri dish with 15 wells, five wells filled with a solution of yam seeds extract, five wells filled amoxicilin and five other wells filled with ethanol 96 %. Observation were made after twenty-four hours the incubation.The result showed that yam seeds extract has antibacterial effect to inhibit the growth of streptococcus mutans bacteria, but the inhibition zone smaller than amoxicillin. Keywords: Yam seeds (Pachyrrhizus erosus), Streptococcus mutans, inhibition zone   ABSTRAK Karies gigi merupakan masalah kesehatan gigi dan mulut yang sering terjadi. Streptococcus mutants merupakan bakteri utama penyebab karies gigi. Penelitian dengan menggunakan bahan alam telah banyak dilakukan. Salah satu tumbuhan yang bermanfaat ialah bengkuang. Biji bengkuang (Pachyrrhizus erosus) mengandung senyawa antibakteri antara lain flavonoid, saponin, tanin, kuonin, alkaloid, dan triterpenoid. Tujuan penelitian ini adalah untuk mengetahui efektivitas ekstrak biji bengkuang terhadap pertumbuhan Streptococcus mutans secara in vitro. Penelitian ini merupakan penelitian eksperimental laboratoris dengan rancangan penelitian post test only control group design. Metode pengujian yang digunakan dalam penelitian ini ialah metode modifikasi Kirby-Bauer dengan menggunakan sumuran. Media MHA disediakan sebanyak lima cawan petri dengan 15 buah sumur, lima sumur diisi dengan larutan ekstrak biji bengkuang, lima sumur diisi amoksisilin dan lima sumur lainnya diisi dengan etanol 96%. Pengamatan dilakukan setelah 24 jam masa inkubasi. Hasil penelitian ini menunjukan bahwa ekstrak biji bengkuang memiliki efek antibakteri untuk menghambat pertumbuhan bakteri Streptococcus mutans, tetapi zona hambatnya lebih kecil dibandingkan dengan antibiotik amoksisilin. Kata kunci: biji bengkuang (Pachyrrhizus erosus), Streptococcus mutans, zona hambat  
EVALUASI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL SPONS Aplysina sp. DIPESISIR PANTAI LEMBEH KOTA BITUNG Hendra, Hendra; Yudistira, Adithya; Sumantri, Surya
PHARMACON Vol 9, No 3 (2020): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.9.2020.30032

Abstract

ABSTRACT Aplysina sp., is one of the marine biota, which forms the coral reefs that contain active compounds, whose percentage of activity is greater than the compounds produced by terrestrial plants. This study aims to analyze the antioxidant activity of the sponge Aplysina sp. Sponge sample Aplysina sp., obtained from the waters of the Lembeh Strait, Bitung. This research is an experimental laboratory by testing the ethanol extract of sponge Aplysina sp., with the DPPH method [1,1-diphenyl-2-picrilhidrazil] to analyze antioxidant activity using a spectrophotometer UV-Vis. The results of this study showed that the ethanolic extract of the sponge Aplysina sp. Lembeh straits waters have antioxidant activity in each concentration test. The highest concentration has an antidote to free radical activity by reaching a percentage of 24,83%. Keywords : Aplysina sp., Antioxidants, Ethanol, DPPH ABSTRAK Spons Aplysina sp. merupakan salah satu biota laut penyusun terumbu karang yang mengandung senyawa aktif yang presentase keaktifannya lebih besar dibandingkan dengan senyawa-senyawa yang dihasilkan oleh tumbuhan darat.Penelitian ini bertujuan untuk menganalisis aktivitas antioksidan dari spons Aplysina sp. Sampel spons Aplysina sp. di peroleh dari perairan Selat Lembeh, Bitung. Penelitian ini merupakan eksperimental laboratorium dengan pengujian terhadap ektrak etanol spons Aplysina sp.dengan metode DPPH [1,1-difenil-2-pikrilhidrazil] untuk menganalisis aktivitas antioksidan dengan menggunakan sprektrofotometer UV-Vis. Hasil penelitian ini memperlihatkan ekstrak etanol spons Aplysina sp.di perairan selat lembeh mempunyai aktivitas antioksidan disetiap konsentrasi pengujiannya. Konsetrasi tertinggi memliki aktivitas penangkal radikal bebas dengan mencapai presentase 24,83%. Kata kunci :Aplysina sp., Antioksidan, Etanol, DPPH
PERBEDAAN JUMLAH PERTUMBUHAN KOLONI BAKTERI RONGGA MULUT SEBELUM DAN SESUDAH MENGGUNAKAN OBAT KUMUR YANG MENGANDUNG CHLORHEKSIDINE Patabnag, Widya A.
PHARMACON Vol 5, No 1 (2016): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.5.2016.11220

Abstract

PERBEDAAN JUMLAH PERTUMBUHAN KOLONI BAKTERI RONGGA MULUT SEBELUM DAN SESUDAH MENGGUNAKAN OBAT KUMUR YANG MENGANDUNG CHLORHEKSIDINE Widya A.Patabang1), Michael A.Leman1), Jimmy Maryono1) 1)Program Studi Pendidikan Dokter Gigi Fakultas Kedokteran   ABSTRACT Mouthwashes often used for daily plaque control, especially for individuals with poor oral clearance. Rinsing with mouthwash can eliminate bacteria in the oral cavity between teeth that are not reached by the toothbrush. Chlorheksidine, a kind of antiseptic used by many health experts as a good dental cleaning and dental disease treatment drugs. Chlorheksidine also grouped into two groups: chlorheksidine nonalcoholic and alcoholic chlorheksidine. The purpose of this study to determine differences in the number of bacterial colonies growing oral cavity before and after using mouthwash containing chlorheksidine. This study is a quasi-experimental research (quasi experiment) with pretest and postest study design controlled group that carried out in the Laboratory of Microbiology, Faculty of Medicine Unsrat with a sample of 10 people. Criteria for inclusion in this study are 20-25 years old, with good oral clearens, and willing to participate in research. Exclusion criteria in this study is taking drugs orally or systemic antibiotics, using braces and there are lesions in the oral cavity.The average value before rinsing with chlorheksidine that 105CFU/mL, and after gargling with chlorheksidine that 101CFU/mL with the differences 104CFU/mL. Conclusion :The results showed that a decline in growth in the number of colonies of bacteria of the oral cavity after rinsing with mouthwash which containing chlorheksidine. Key words :mouthwashes, colonies of bacteria, chlorheksidine     ABSTRAK Obat kumur sering digunakan untuk kontrol plak sehari-hari, khususnya bagi individu dengan kebersihan mulut yang buruk. Berkumur dengan obat kumur dapat menghilangkan bakteri rongga mulut di cela-cela gigi yang tidak terjangkau oleh sikat gigi. Chlorheksidine jenis antiseptik yang banyak digunakan oleh para ahli kesehatan gigi baik sebagai pembersih dan obat pengobatan penyakit gigi. Chlorheksidine dikelompokkan menjadi dua kelompok yaitu chlorheksidine tanpa alkohol dan chlorheksidine beralkohol. Tujuan penelitian ini untuk mengetahui perbedaan jumlah pertumbuhan koloni bakteri rongga mulut sebelum dan sesudah menggunakan obat kumur yang mengandung chlorheksidine.Penelitian ini merupakan penelitian eksperimental semu (quasi eksperiment) dengan rancangan penelitian pretest dan postestcontrolled grup yang dilaksanakan di Laboratorium Mikrobiologi Fakultas Kedokteran Unsrat dengan sampel sebanyak 10 orang. Kriteria inklusi dalam penelitian ini yaitu berusia 20-25 tahun, kebersihan mulut yang baik, dan bersedia berpartisipasi dalam penelitian. Kriteria ekslusi dalam penelitian ini yaitu mengonsumsi obat-obatan oral maupun antibiotik sistemik, menggunakan kawat gigi dan terdapat lesi dalam rongga mulut.  Hasil penelitian menunjukkan nilai rata-rata sebelum berkumur dengan chlorheksidine yaitu 105CFU/mL dan sesudah berkumur dengan chlorheksidine yaitu 101CFU/mL dengan nilai selisih 104CFU/mL. Kesimpulan Penurunan pertumbuhan jumlah koloni bakteri rongga mulut sesudah berkumur dengan obat kumur yang mengandung chlorheksidine.   Kata kunci : obat kumur, koloni bakteri, chlorheksidine  
UJI EFEK ANALGETIK EKSTRAK ETANOL DAUN LAMTORO (Leucaena Leucocephala (LAM) de Wit) PADA MENCIT PUTIH JANTAN (Mus musculus) Ishak, Megawati
PHARMACON Vol 6, No 4 (2017): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.6.2017.17728

Abstract

UJI EFEK ANALGETIK EKSTRAK ETANOL DAUN LAMTORO (Leucaena Leucocephala (LAM) de Wit) PADA MENCIT PUTIH JANTAN (Mus musculus) Megawati Ishak1), Widdhi Bodhi1), Gayatri Citraningtyas1)1)Jurusan Farmasi, FMIPA, Universitas Sam Ratulangi, Manado, 95115 ABSTRACT             Pain is defined as an unpleasant sensory and emotional experience associated with tissue damage. People used lamtoro leaves to reduce muscle pain, burns, and swelling. So it is suspected that the lamtoro plant has an analgesic effect. (Leucaena leucocephala (Lam) de Wit) contains potencial active flavonoids to reduce pain. The aim of this research was to evaluate the analgetic effect of leaf extract of lamtoro with dose of 0.54 g, 0.72 gand 1.08 g in male white mice. The subjects of this study were 15 males of white mice divided into 5 groups: negative control group (CMC 1%), positive control group (Paracetamol), and treatment group (lamtoro leaf extract). The test of analgesic effect was done by giving heat stimulation with temperature of 55ºC. Response of mice was observed in the form of licking movement of hind legs and jumping movement. Observation performed for 1 minute. Observation done before giving of test substance, then consecutively giving at the minute of 30, 60, 90, and 120, respectively. The results showed that the extract of lamtoro leaf with dose of 0.54 g, 0.72 g, and 1.08 g had analgesic effect on male white mice. It was concluded that leaf extract of lamtoro had an analgesic effect on male mice that were induced in thermic.  Keywords: Analgesic effect, leaf lamtoro, white male mice  ABSTRAKNyeri didefenisikan sebagai suatu pengalaman sensorik dan emosional yang tidak menyenangkan yang berhubungan dengan kerusakan jaringan. Sebagian masyarakat menggunakan daun lamtoro untuk mengurangi nyeri otot, luka bakar, dan bengkak. sehingga diduga bahwa tanaman lamtoro mempunyai efek analgetik. Daun lamtoro (Leucaena leucocephala (Lam) de Wit) mengandung zat aktif flavonoid yang berpotensi untuk mengurangi rasa nyeri. Penelitian ini bertujuan untuk mengetahui ada tidaknya efek analgetik dari ekstrak daun lamtoro dengan dosis 0,54 g, 0,72 g, dan 1,08 g pada mencit putih jantan. Subjek penelitian ini ialah 15 ekor mencit putih jantan yang dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (CMC 1%), kelompok kontrol positif (Parasetamol), dan kelompok perlakuan (ektrak daun lamtoro). Pengujian efek analgetik dilakukan dengan cara memberikan rangsangan panas dengan suhu 55ºC. Respon mencit yang diamati yaitu berupa gerakan menjilat kaki belakang dan melompat. Pengamatan dilakukan selama 1 menit. Pengamatan dilakukan sebelum pemberian zat uji, kemudian berturut-turut pada menit ke-30, 60, 90, dan 120. Hasil penelitian menunjukan ekstrak daun lamtoro dengan dosis 0,54 g, 0,72 g dan 1,08 g memiliki efek analgetik pada mencit putih jantan. Dengan demikian dapat disimpulkan bahwa ekstrak daun lamtoro memiliki efek analgetik pada mencit putih jantan yang di induksi secara termik.  Kata kunci : Analgetik, Daun Lamtoro, Mencit Putih Jantan
UJI EFEK EKSTRAK ETANOL KULIT TERUNG UNGGU (Solanum melongena L.) TERHADAP KADAR GULA DARAH PADA TIKUS PUTIH JANTAN GALUR WISTAR (Rattus norvegicus) Aer, Brenda Natalia
PHARMACON Vol 2, No 4 (2013)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.3103

Abstract

This study aimed to determine the effect of ethanol extract eggplant rind (SolanummelongenaL.) on blood sugar levels in white male wistar induced by sucrose. Extraction is done bymaceration with 95% ethanol. The subject of the experiment were 15 white male wistarwhich were divided into 3 (three) groups namely positive control group using metformin 9mg/Kg body weight, negative control group using CMC 1% and treatment group with thedose of 0,02 g/200 g body weight, 0,01 g/200 g body weight and 0,1 g/200 g body weight.The data is processed using ANOVA and LSD test to compare between the positive controlgroup, negative control group, and treatment group. The analysis revealed a significantdifference between negative control group and treatment group, negative control group andpositive control group, but did not show a significant difference between positive controlgroup and treatment group.Key words : Solanummelongena L., Eggplant Rind, Blood Sugar Level, Sucrose
UJI EFEK ANTIINFLAMASI EKSTRAK ETANOL KULIT BATANG JAMBU BIJI (PSIDIUM GUAJAVA) TERHADAP EDEMA KAKI TIKUS JANTAN GALUR WISTAR Lanti, Deliyana; Fatimawali, Fatimawali; Wullur, Adeanne
PHARMACON Vol 1, No 2 (2012)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.1.2012.508

Abstract

Inflamation is a protective response of body from injury of cell. Edema is one ofinflammation sign. Guava stem leather contains of flavonoid which has potency to inhibitedema. The aims of this research were to study antiinflamation effect of ethanolic extractofguava stem leather (Psidium guajava L.) on edema of white mice strain wistar legs.Thesubjects in this research were 25 wistar male which divided into 5 groups, namely negativecontrol (aquades), positive control (indometasin) and extract group with concentration 1%,2% and 4%. Every group consists of five mices. Aquades, indometasin and extractsupplementation were done per oral, followed with 5% of white egg induction on mice leftleglead to edema formation.Measurement of edema volume was done using plestimometer,and observation of edema were made every hour during 7 hours. Data which obtained wereanalyzed with ANOVA, if there is a differences between treatment, analysis continue to LSDtest. The result shows that supplementation of ethanolic extract of guava stem leatherconcentration 1% and 2 % decrease edema significantly with percent of inhibition 37,37 and32,59%, but supplementation of ethanolic extract of guava stem leather concentration 1% didnot shows inhibition effect .Keywords: guava stem leather, antiinflamation, edema
POTENSI EKSTRAK ETANOL TANGKAI DAUN TALAS (Colocasia esculenta [L]) SEBAGAI ALTERNATIF OBAT LUKA PADA KULIT KELINCI (Oryctolagus cuniculus) Wijaya, Bryan Alfonsius
PHARMACON Vol 3, No 3 (2014)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.3.2014.5419

Abstract

ABSTRACTTaro (Colocasia esculenta [L]) is a cylindrical shaped plant that has a pseudo stalk and lightbrown colored bulbs. The heart shaped leaves are elongated and the leaf surfaces arewaterproof which presumably can heal wounds . The purpose of this study was to test theethanol extract of taro leaf stalk as an alternative drug in the skin wounds of rabbits(Oryctolagus cuniculus) and phytochemical screening of compounds which act to curewounds. Nine rabbits were used as test animals and were divided into 3 groups (treatment A,B, and C). Treatment A: wound was given ± 0.2 g betadine drug (positive control), treatmentB: wound was given ± 0.2 g Taro stem extract, treatment C: wound was given no treatment(negative control). The wound was smeared 2 times a day using betadine liquid (positivecontrol) and the wound was smeared 2 times a day by using Taro stem extract. Observationsof the injuries were done every day (day 0 to day 9). From the observations, it can beinferred that Taro stem extract has potential as an alternative drug to cuts because itdemonstrated wound healing activity on rabbit skin, so the test showed that Taro stems andleaves contain the phytochemical extracts saponins, flavonoids, tannins, alkaloids, steroidsand terpenoids.Key words : Taro Leaf Stem, Rabbit, Cut, Phytochemistry TestABSTRAKTalas (Colocasia esculenta [L]) merupakan tumbuhan yang memiliki tangkai daun yangsemu, berbentuk silindris dan memiliki umbi berwarna coklat muda, sedangkan pada bagiandaun berbentuk seperti jantung yang memanjang dan permukaan daun yang tahan air(waterproof) yang di duga dapat menyembuhkan luka. Tujuan dari penelitian ini ialah untukmenguji ekstrak etanol tangkai daun Talas sebagai alternatif obat luka pada kulit kelinci(Oryctolagus cuniculus) dan skrining senyawa fitokimia yang berperan sebagai obat luka.Hewan uji yang digunakan sebanyak 9 ekor kelinci yang dibagi menjadi 3 kelompok(perlakuan A, B, dan C). Perlakuan A : luka diberi ± 0,2 g obat betadine (kontrol positif),perlakuan B : luka diberi ± 0,2 g ekstrak tangkai daun Talas, perlakuan C : luka tanpaperlakuan (kontrol negatif). Luka dioles 2 kali sehari dengan menggunakan betadine cair(kontrol positif) dan luka dioles 2 kali sehari dengan menggunakan ekstrak tangkai daunTalas. Pengamatan luka dilakukan setiap hari (hari ke-0 sampai hari ke-9), dari hasilpengamatan disimpulkan ekstrak batang Talas dapat berpotensi sebagai alternatif obat lukasayatan karena telah menunjukkan aktivitas penyembuhan luka pada kulit kelinci, sehinggadilakukan uji fitokimia yang menunjukkan bahwa ekstrak tangkai daun Talas mengandungansaponin, flavonoid, tanin, alkaloid, steroid dan terpenoid.Kata kunci : Tangkai Daun Talas, Kelinci, Luka, Uji Fitokimia
STRATEGI PENGEMBANGAN INSTALASI FARMASI RSUD DATOE BINANGKANG DI KABUPATEN BOLAANG MONGONDOW MENGGUNAKAN ANALISIS SWOT Ardiany, Wahyu M.; Citraningtyas, Gayatri; Mpila, Deby A.
PHARMACON Vol 9, No 3 (2020): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.9.2020.30023

Abstract

ABSTRACTPharmacy Installation plays a role in providing quality health services in Hospitals, it was necessary to have an analysis of the development strategy of the Pharmacy Installation at RSUD Datoe Binangkang in accordance with internal and external conditions.  This studied aims to determine the development strategy in the Pharmacy Installation of RSUD Datoe Binangkang used SWOT analysis. The methods used in this research are quantitative and qualitative methods with descriptive research designs used questionnaires, interviews and observations.  The results showed that the Pharmacy Installation of RSUD Datoe Binangkang was at coordinates point x = 1,048 and    y = 0,779. The Pharmacy Installation of RSUD Datoe Binangkang was at the first quadrant and it can be said to be strong and likely. Conclusions gained that the strategy used was an aggressive strategy. Keywords: Development strategy, Pharmacy Installation, SWOT  ABSTRAKInstalasi Farmasi berperan dalam memberikan pelayanan kesehatan yang berkualitas di Rumah Sakit, sehingga diperlukan adanya analisis strategi pengembangan Instalasi Farmasi di RSUD Datoe Binangkang yang sesuai dengan kondisi internal dan eksternal. Penelitian ini bertujuan untuk menentukan strategi pengembangan di Instalasi Farmasi RSUD Datoe Binangkang dengan menggunakan analisis SWOT. Metode yang digunakan dalam penelitian ini merupakan metode kuantitatif dan kualitatif dengan rancangan penelitian deskriptif menggunakan kuisioner, wawancara dan observasi. Hasil penelitian menunjukan bahwa Instalasi Farmasi RSUD Datoe Binangkang berada pada titik koordinat x = 1,048 dan y = 0,779. Instalasi Farmasi RSUD Datoe Binangkang berada pada kuadran pertama sehingga dapat dikatakan kuat dan berpeluang. Kesimpulan yang didapat bahwa strategi yang digunakan adalah strategi agresif. Kata kunci: Strategi pengembangan, Instalasi Farmasi, SWOT
ANALISIS RHODAMIN B PADA LIPSTIK YANG BEREDAR DI PASAR KOTA MANADO Mamoto, Lidya Valda; Fatimawali, Fatimawali; Citraningtyas, Gayatri
PHARMACON Vol 2, No 2 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.1689

Abstract

Rhodamin B is a synthetic dye that banned for use in cosmetics and is certified as ahazardous material according to Minister of Health of Indonesian Republic No.376/Menkes/Per/1990 because it cause liver damage, kidney and lymph glands damage,followed with anatomy changes such as organ enlargement. Rhodamin B dye is often usedfor food and beverage products. The study was conducted to identify Rhodamin B in lipstickin the market of Manado City. Samples was taken from 3 main market in Manado city,namely Karombasan market, Pasar 45 market, and Bersehati market. Samples were soakedwith amonia solution, then using wool yarn to extract rhodamin B dye, followed byidentification using thin layer chromatography (TLC) then detected with UV light 254 and366 nm. Rhodamin B was evaluated using UV-Vis spectrophotometry. The result shows that9 examined samples doesn’t contain rhodamin BKeywords : Rhodamin B, Lipstick, thin layer chromatography (TLC), UV-VisSpectrophotometry.

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