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Pharmacy Study Program, Faculty of Mathematics and Natural Science, Sam Ratulangi University, Manado, North Sulawesi, Indonesia, 95115
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INDONESIA
PHARMACON
Published by Universitas Sam Ratulangi
ISSN : 23022493     EISSN : 27214923     DOI : 10.35799
Core Subject : Health,
Medicine & Pharmacology
Pharmacon is the journal published by Pharmacy Study Program, Faculty of Mathematics and Natural Sciences, Sam Ratulangi University, Indonesia (P-ISSN: 2302-2493 E-ISSN: 2721-4923). Pharmacon was established in 2012 and published four times a year. Pharmacon is an open access journal and has been indexed by main indexing Google Scholar, GARUDA, Crossref.
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Articles 1,131 Documents
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ISOLASI DAN IDENTIFIKASI FLAVONOID DALAM DAUN LAMUN (SYRINGODIUM ISOETIFOLIUM) Rompas, Romario Aldi; Edy, Hosea Jaya; Yudistira, Adithya
PHARMACON Vol 1, No 2 (2012)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.1.2012.487

Abstract

Sea grass is a group of flowering plant, leaved, has its own roots and live in a shallow water.It usually used to capture sediment, compost, and as antioxidant. The use of sea grass onhuman needs to be conducted. Because of its potency and its component such as flavonoids, aresearch to identify kind of flavonoids in sea grass must be conducted. The aims of thisresearch are to isolate and identify flavonoids in sea grass (Syringodium isoetifolium) usingthin layer chromatography and spectrophotometer UV-Vis. Extraction was done withmaceration using ethanol 96% as solvent. Isolation was done by Thin Layer ChromatographyGF 6054, and n-butanol : acetic acid : water (BAA) (4:1:5). There are two spot after isolatewith TLC, the first is yellow spot with Rf 0,4 and second is red with Rf 0,8. Identification offlavonoids was done using spectrophotometer UV-Vis. Based on results, sea grass consist onflavonoids, suspected chalcon group.Keywords : sea grass, flavonoids, thin layer chromatography, UV-vis
ANALISIS KEPUASAN PASIEN POLIKLINIK GIGI DAN MULUT RUMAH SAKIT TINGKAT III 07.06.01 ROBERT WOLTER MONGINSIDI TERHADAP PELAYANAN BPJS KESEHATAN BULAN AGUSTUS 2015 Calvin Nathanael1), Vonny N. Nathanael, Calvin
PHARMACON Vol 5, No 2 (2016): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.5.2016.12178

Abstract

ANALISIS KEPUASAN PASIEN POLIKLINIK GIGI DAN MULUT RUMAH SAKIT TINGKAT III 07.06.01 ROBERT WOLTER MONGINSIDI TERHADAP PELAYANAN BPJS KESEHATAN BULAN AGUSTUS 2015 Calvin Nathanael1), Vonny N. S. Wowor1), Michael A. Leman1) 1Program Studi Pendidikan Dokter Gigi Fakultas Kedokteran Universitas Sam Ratulangi Manado Email: calvin.meliala@gmail.com   ABSTRACT Health is the basic human need that must be fulfilled by people. Indonesian Government has implemented National Health Insurance as an effort to guarantee every citizen’s life basic needs. National Health Insurance in Indonesia that is considered as social health insurance system is conducted by BPJS Kesehatan since 2014. BPJS Kesehatan that has been being already operated for more than a year in Indonesia has eight targets to achieve in 2019. One of those targets is that 85% of participants are satisfied with the service done by BPJS Kesehatan. The purpose of this study is to find out the satisfaction of the patient’s of Poliklinik Gigi dan Mulut Rumah Sakit Tingkat III 07.06.01 Robert Wolter Monginsidi towards the services given by BPJS Kesehatan. The type of this study is a descriptive analytic study with cross sectional method. The sampling method used in this study is purposive sampling with 61 sample. The patient’s satisfaction is measured with SERVQUAL and analyzed with Importance Performance Analysis to find out which service items that those need to be improved. The data was collected using two type of questionnaires. They were given before and after the patients got the service. The result shows that services given by BPJS Kesehatan towards the patient’s of Polinklinik Gigi dan Mulut Rumah Sakit Tingkat III 07.06.01 Robert Wolter Monginsidi is still less satisfying. The management then should focus to improve their service performances for the better and satisfying service in the future. Key words: Satisfaction, BPJS Kesehatan , SERVQUAL, importance performance analysis ABSTRAK Kesehatan merupakan kebutuhan dasar yang mutlak dipenuhi oleh setiap manusia. Pemerintah Indonesia melaksanakan Jaminan Kesehatan Nasional sebagai upaya untuk menjamin warga negaranya dapat memenuhi kebutuhan dasar hidup yang layak. Jaminan Kesehatan Nasional di Indonesia yang tergolong sistem jaminan kesehatan sosial diselenggarakan oleh BPJS Kesehatan mulai tahun 2014. BPJS Kesehatan yang telah beroperasi lebih dari setahun di Indonesia memiliki delapan target yang ingin dicapai pada tahun 2019, salah satunya ialah 85% peserta puas dengan layanan BPJS Kesehatan. Tujuan penelitian ini ialah untuk mengetahui kepuasan pasien yang berkunjung ke Poliklinik Gigi dan Mulut Rumah Sakit Tingkat III 07.06.01 Robert Wolter Monginsidi terhadap pelayanan BPJS Kesehatan. Jenis penelitian ini ialah deskriptif analitik dengan metode cross sectional. Metode penarikan sampel yang digunakan yaitu purposive sampling dengan jumlah sampel sebanyak 61 orang. Kepuasan pasien diukur menggunakan metode SERVQUAL dan dianalisis menggunakan Importance Performance Analysis untuk mengetahui item pelayanan mana saja yang kinerjanya perlu ditingkatkan. Data diperoleh dengan menggunakan kuesioner sebelum pasien mendapatkan pelayanan dan setelah pasien selesai mendapatkan pelayanan.Hasil penelitian menunjukkan pelayanan BPJS Kesehatan terhadap pasien Polinklinik Gigi dan Mulut Rumah Sakit Tingkat III 07.06.01 Robert Wolter Monginsidi masih kurang memuaskan. Manajemen perlu fokus pada pembenahan kinerja pelayanan sehingga lebih baik dan memuaskan di masa mendatang. Kata kunci: Kepuasan, BPJS Kesehatan , SERVQUAL, importance performance analysis
AKTIVITAS ANTIMIKROBA DARI EKSTRAK ASCIDIAN Herdmania momus PADA MIKROBA PATOGEN MANUSIA Mujipradhana, Vidhiya N.
PHARMACON Vol 7, No 3 (2018): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.7.2018.20601

Abstract

AKTIVITAS ANTIMIKROBA DARI EKSTRAK ASCIDIAN Herdmania momus PADA MIKROBA PATOGEN MANUSIAVidhiya Nanda Mujipradhana1), Defny S. Wewengkang1), Edi Suryanto2)1)Program Studi Farmasi FMIPA UNSRAT Manado, 951152)Program Studi Kimia FMIPA UNSRAT Manado, 95115ABSTRACTAscidian is one of the marine biota that has not received serious attention, but has considerable potentially in Indonesian waters. Potential ascidians serve a exploratory material for the search for new bioactive compounds as drug candidates for the pharmaceutical world. This study aims to determine the antimicrobial activity of extract and ascidian fraction of Herdmania momus obtained from Manado bay againts Staphylococcus aureus microbes, Escherichia coli, and Candida albicans. Samples were extracted by maceration and fractionation using ethanol, methanol, chloroform, and n-hexane. Antimicrobial activity was performed by agar diffusion method (Kirby and Bauer). The results showed that rough extract of ethanol, methanol fraction, chloroform fraction, and n-hexane fraction effectively inhibited microbial Staphylococcus aureus, Escherichia coli, and Candida albicans, extracts and fractions were categorized medium except for n-hexane fraction againts Candida albicans microorganisms were very strong categorized based on the theory of Davis and Stout.Keywords : Ascidian Herdmania momus, antimicrobial activity, inhibitory zone, Staphylococcus aureus, Escherichia coli, Candida albicans.ABSTRAKAscidian merupakan salah satu biota laut yang belum mendapat perhatian yang serius, namun mempunyai potensi yang cukup besar di perairan Indonesia. Ascidian potensial dijadikan sebagai bahan eksplorasi pencarian senyawa bioaktif baru sebagai calon obat untuk dunia farmasi. Penelitian ini bertujuan untuk menentukan adanya aktivitas antimikroba dari estrak dan fraksi ascidian Herdmania momus yang diperoleh dari teluk Manado terhadap mikroba Staphylococcus aureus, Escherichia coli, dan Candida albicans. Sampel diekstraksi secara maserasi dan fraksinasi menggunakan etanol, metanol, kloroform, dan n-heksana. Aktivitas antimikroba dilakukan dengan metode difusi agar (Kirby dan Bauer). Hasil penelitian menunjukkan bahwa ekstrak kasar etanol, fraksi metanol, fraksi kloroform, dan fraksi n-heksana efektif menghambat mikroba Staphylococcus aureus, Escherichia coli, dan Candida albicans, ekstrak dan fraksi dikategorikan sedang kecuali untuk fraksi n-heksana terhadap mikroba Candida albicans dikategorikan sangat kuat berdasarkan teori Davis dan Stout.Kata Kunci : Ascidian Herdmania momus, aktivitas antimikroba, zona hambat, Staphylococcus aureus, Escherichia coli, Candida albicans. 
AKTIVITAS ANTIOKSIDAN EKSTRAK KULIT BIJI BUAH PINANG YAKI (Areca Vestiaria Giseke) YANG DI EKSTRAKSI SECARA SOKLET Mamonto, Siti Iqroma
PHARMACON Vol 3, No 3 (2014)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.3.2014.5399

Abstract

ABSTRACT This study was conducted to determine the antioxidant activity of extracts of seed coat Yaki Pinang (Areca Vestiaria Giseke) were extracted in soxhlet using methanol, ethyl acetate and chloroform as well as antioxidant test method FRAP (Ferric Reducing Antioxidant Power) using UV-Vis spectrophotometer. The results showed Soxhlet method using methanol solvent have antioxidant activity of gallic acid equivalent to the value of the methanol extract of 59.33 EN ag/g, then the EN Chloroform 18.8 ag/g, ethyl acetate 46.26 EN ag/g,   Key words : FRAP, Antioxidant, Areca Vestiaria Giseke, Spectrophotometer UV-Vis       ABSTRAK Penelitian ini dilakukan untuk mengetahui aktivitas antioksidan ekstrak kulit biji Pinang Yaki (Areca Vestiaria Giseke) yang diekstraksi secara soxhlet menggunakan pelarut metanol, etil asetat dan kloroform serta uji antioksidan metode FRAP (Ferric Reducing Antioxidant Power) menggunakan Spektrofotometer UV-Vis. Hasil penelitian menunjukkan metode soxhlet dengan menggunakan pelarut metanol memiliki aktivitas antioksidan dengan nilai equivalen asam galat ekstrak metanol sebesar 59,33 E N ag/g, kemudian pada Kloroform 18,8 E N ag/g, etil asetat 46,26 E N ag/g,   Kata kunci : FRAP, Antioksidan, Areca Vestiaria Giseke dan Spektrofotometer UV-Vis        
ANALISIS KEPUASAN PASIEN RAWAT JALAN TERHADAP PELAYANAN DI INSTALASI FARMASI RUMAH SAKIT BHAYANGKARA MANADO Kaunang, Venesya Natalia Putri; Citraningtyas, Gayatri; Lolo, Widya Astuty
PHARMACON Vol 9, No 1 (2020)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.9.2020.27445

Abstract

ABSTRACT Patient satisfaction is an important indicator for service quality and has implications for the delivery of services more efficiently in meeting patient needs. A good quality of service will provide patients satisfaction to and it will affect patients to hospital if needed. The purpose of this study was to determine the satisfaction of outpatients with services in the Pharmacy Installation at the Bhayangkara Hospital in Manado. The type and design of the study used is a type of descriptive research with a cross-sectional approach. Patient satisfaction was measured using the SERVQUAL (Service Quality) method. The result of this study, tangible   (-0.26), assurance (0-305), empathy (-0.37), responsiveness (-0.69), and the lowest is reliability (-0.86). It can be concluded that the overall satisfaction score is in the negative index, meaning that the patient is not satisfied with the services provided at the Pharmacy Installation. Keywords: Patient Satisfaction, SERVQUAL, Pharmacy Installation, Bhayangkara Hospital Manado. ABSTRAKKepuasan pasien merupakan indikator penting bagi kualitas pelayanan dan memiliki implikasi bagi penyelenggaraan pelayanan lebih efisien dalam memenuhi kebutuhan pasien. Kualitas pelayanan yang baik akan memberikan kepuasan kepada pasien serta kepuasan pasien akan memengaruhi pasien untuk kembali lagi ke Rumah Sakit tersebut bila membutuhkan. Tujuan dari penelitian ini untuk mengetahui kepuasan pasien rawat jalan terhadap pelayanan di Instalasi Farmasi Rumah Sakit Bhayangkara Manado. Jenis dan rancangan penelitian yang digunakan adalah jenis penelitian deskriptif dengan pendekatan secara cross-sectional. Kepuasan pasien diukur menggunakan metode SERVQUAL (Service Quality). Hasil penelitian ini. secara berturut-turut yaitu reliability  (-0.86), responsiveness (-0.69), emphaty (-0.37), assurance (0-305) dan yang terendah adalah tangible (-0.26) secara berturut-turut yaitu reliability  (-0.86), responsiveness (-0.69), emphaty (-0.37), assurance (0-305) dan yang terendah adalah tangible (-0.26). Kesimpulannya yaitu nilai kepuasan secara keseluruhan berada pada indeks negatif, artinya bahwa pasien belum merasa puas terhadap pelayanan yang diberikan di Instalasi Farmasi. Kata kunci : Kepuasan Pasien, SERVQUAL, Instalasi Farmasi, Rumah Sakit Bhayangkara Manado
GKANDUNGAN VINKRISTIN PADA KULTUR KALUS Catharaanthus roseus (L) G. DON YANG DIBERI PERLAKUAN TRIPTOFAN DAN VINDOLIN Lombonbitung, Ellen
PHARMACON Vol 4, No 4 (2015): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.4.2015.10201

Abstract

KANDUNGAN VINKRISTIN PADA KULTUR KALUS Catharaanthus roseus (L) G. DON YANG DIBERI PERLAKUAN TRIPTOFAN DAN VINDOLIN Ellen Lombonbitung1), W. Tilaar1), Dingse Pandiangan2) 1)Program Studi Agronomi, Pasca Sarjana Universitas Sam Ratulangi Manado 2)Jurusan Biologi Fak. MIPA Universitas Samratulangi Manado.   ABSTRACT Catharanthus roseus (L) G. Don also called Tapak dara plant is cultivated plant, besides its function as ornamental plant but also can be functioned as medicinal plant. Alkaloid compounds from this plant has been isolated and used as an anti cancer drug, are vinblastine and vincristine. Vinblastin and vincristine were poor alkaloid compounds produced in plants. Vincristine made from joined catharantine and vindolin, cause it is expected that vindolin be able to increase the content of  vincristine. The research was carried out to knew the vincristine content of  callus culture were given tryptophan treatment and vindolin. The research plan used was completely random design, by tryptophan combination (0, 75 and 150 mg/L) and Vindolin (0, 0,2, 0,4 and 0,6 mg/L), factorial. The vincristine content was determined  by high performance liquid chromatography (HPLC). Based on HPLC data, it was made standar curve and regression linear equation that describe the relationship between standar vincristine concentration of area. The obtained result from the research proved the tryptophan and vindoline treatment affecting the vincristine content. The highest vincristine content was showed to T1V0 treatment (Tryptophan 150 mg/L and Vindolin 0 mg/L), is 2,352 µg/g dw.   Keywords : Vincristine, Tryptophan, Vindolin ABSTRAK Catharanthus roseus (L) G. Don yang disebut juga tanaman tapak dara merupakan tanaman yang banyak dibudidayakan selain sebagai tanaman hias juga berkhasiat obat. Senyawa kelompok alkaloid dari tanaman ini telah diisolasi dan dijadikan obat anti kanker, yaitu vinblastin dan vinkristin. Vinblastin dan vinkristin adalah senyawa alkaloid yang sangat kecil dihasilkan dalam tanaman. Produksi alkaloid dari Catharanthus roseus (L) G. Don   Vinkristin terbentuk dari gabungan katarantin dengan vindolin, karena itu diharapkan dengan vindolin dapat meningkatkan kandungan vinkristin. Penelitian dilakukan untuk mengetahui Kandungan  Vinkristin pada Kultur Kalus Catharanthus roseus (L) G. Don yang diberi Perlakuan Triptofan dan Vindolin. Rancangan penelitian yang digunakan adalah Rancangan Acak Lengkap (RAL) secara faktorial dengan  perlakuaan kombinasi triptofan (0, 0,75 dan 150 mg/L) dan vindolin (0, 0,2, 0,4 dan 0,6 mg/L). Kandungan Vinkristin ditentukan dengan menggunakan metoda Kromatografi Cair Kinerja Tingggi (KCKT). Berdasarkan hasil KCKT dibuat kurva standar      dan persamaan regresi yang menggambarkan hubungan antara konsentrasi vinkristin standar terhadap luas area. Hasil yang diperoleh dari penelitian ini membuktikan perlakuan triptofan dan vindolin mempengaruhi kandungan vinkristin. Kandungan vinkristin tertinggi berada pada perlakuan T1V0 (Triptofan 75 mg/L dan Vindolin 0 mg/L), yaitu sebesar 2,352 µg/g bk. Kata Kunci : Vinkristin, Triptofan, Vindolin   
FORMULASI SEDIAAN SABUN CAIR ANTISEPTIK EKSTRAK ETANOL BUNGA PACAR AIR (Impatiens balsamina L.) DAN UJI EFEKTIVITASNYA TERHADAP BAKTERI Staphylococcus aureus SECARA In Vitro Dimpudus, Stefanie A.
PHARMACON Vol 6, No 3 (2017): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.6.2017.16885

Abstract

FORMULASI SEDIAAN SABUN CAIR ANTISEPTIK EKSTRAK ETANOL BUNGA PACAR AIR (Impatiens balsamina L.) DAN UJI EFEKTIVITASNYA TERHADAP BAKTERI Staphylococcus aureus SECARA In VitroStefanie Amelia Dimpudus1), Paulina V.Y.Yamlean1), Adithya Yudistira1)1)Program Studi Farmasi FMIPA UNSRAT Manado, 95115 ABSTRACT Garden balsam (Impatiens balsamina L.) contains anthocyanin compounds, which have antioxidant and antibacterial. The aim of this research is to formulate the liquid soap from the ethanol extract of Garden balsam and to test the antibacterial effectiveness of liquid soap from the ethanol extract of Garden balsam with concentration of 5%, 10% and 15% to Staphylococcus aureus bacteria growth. Liquid soap formulations from the ethanol extract of Garden balsam with concentration 5%, 10% and 15% then done by organoleptic test, pH, high foam, moisture content, free alkali and weight type test. Testing of antibacterial effectiveness on growth of Staphylococcus aureus was done by diffusion method. The results of quality test of liquid soap that meets the requirements according to standard of SNI were organoleptic test, pH, high foam, moisture content, free alkali and weight type test. The results of antibacterial effectiveness test of liquid soap from the ethanol extract of Garden balsam obtained that can inhibit Staphylococcus aureus bacteria, that is with concentration 5%, 10% and 15% which fall into category of medium inhibition zone. Keywords: Garden balsam, Liquid Soap, Antibacterial Effectiveness Test ABSTRAK Bunga Pacar air (Impatiens balsamina L.) mengandung senyawa antosianin yang bersifat sebagai antiosksidan dan antibakteri. Penelitian ini bertujuan untuk memformulasi sediaan sabun cair ekstrak etanol bunga Pacar air dan menguji efektivitas antibakteri sabun cair ekstrak etanol bunga Pacar air dengan konsentrasi 5%, 10% dan 15% terhadap pertumbuhan bakteri Staphylococcus aureus. Formulasi sabun cair ekstrak etanol bunga Pacar air dengan konsentrasi 5%, 10% dan 15% dilakukan pengujian organoleptik, pH, tinggi busa, kadar air, kadar alkali bebas dan bobot jenis. Pengujian efektivitas antibakteri terhadap pertumbuhan Staphylococcus aureus dilakukan dengan metode difusi. Hasil pengujian mutu sabun cair yang memenuhi persyaratan sesuai standar yang ditetapkan SNI ialah uji organoleptik, pH, tinggi busa, kadar air, kadar alkali bebas dan bobot jenis. Hasil uji efektivitas antibakteri sabun cair ekstrak etanol bunga Pacar air yang diperoleh dapat menghambat bakteri Staphylococcus aureus, yakni dengan konsentrasi 5 %, 10% dan 15% masuk dalam kategori zona hambat yang sedang.Kata Kunci: Bunga Pacar Air, Sabun Cair, Uji Efektivitas Antibakteri 
Uji Efektivitas Eksrak Kulit Pisang Goroho (Musa Acuminate L.) Terhadap Penurunan Kadar Glukosa Darah pada Tikus Putih Jantan Galur Wistar yang diinduksi Sukrosa Syamsuddin, Sri Murti Sari; Edy, Hosea Jaya; Supriati, Hamidah Sri
PHARMACON Vol 2, No 1 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.890

Abstract

ABSTRACT The objectives of this research were to study the effect of Goroho banana (Musa Acuminate L.) peel extract on the decreasing of blood glucose content  of white male wistar induced with sucrose. This research using Randomized Controlled Group Design .The subjects in these research were 15 mices which divided into 3 groups, namely negative control (aquadest),  treatments groupusing Goroho banana peel extract 0,03 g/KgBB, and positive control using metformin 45 mg/KgBB. Data were obtained from fasting blood glucose examination, 30 minutes after induced with sucrose, and at 15, 30, 60, and 120 minutes treatment. Data analyzed statistically using ANOVA (Analysis Of Variant), the results extract goroho banan peel provide an effect on blood glucose content. LSD (Least Significant Different) domonstrate distinct difference, significant effect between negative group with treatment, negative group with positive group, but did not show differences between treatment group with positive group. Is Goroho banana peel extract exhibit activity to decrease blood glucose content of white male wistar induced with sucrose. Keywords: Musa acuminate L. goroho banana peel, blood glucose content, sucrose
POTENSI DRUG RELATED PROBLEMS (DRPs) PADA PASIEN GAGAL GINJAL DI RAWAT INAP RSUP PROF. DR. R. D. KANDOU MANADO Luntungan, Prilly
PHARMACON Vol 5, No 3 (2016): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.5.2016.12934

Abstract

POTENSI DRUG RELATED PROBLEMS (DRPs) PADA PASIEN GAGAL GINJAL DI RAWAT INAP RSUP PROF. DR. R. D. KANDOU MANADO   Prilly Luntungan1), Heedy Tjitrosantoso1), Paulina V. Y. Yamlean1) 1)Program Studi Farmasi FMIPA UNSRAT Manado, 95115   ABSTRACT The use of drugs to patients with kidney failure can cause Drug Related Problems (DRPs). DRPs are any incidents involving medication therapy of patients who are actually or potentially will affect the outcome of desired therapeutic. This research aims to determine the Drug Related Problems (DRPs) in patients with renal failure in the inpatient department of Prof. DR. R. D. Kandou Manado. This study was conducted prospectively during May 2016 for inpatient B Hospital Prof. DR. R. D. Kandou Manado. This research was conducted on 27 patients with a medical record of chronic kidney disease. The results showed the number of drug-related problems are known to potentially experience DRPs are indications without treatment (3.6%), without therapy indication (0%), improper drug selection (0%), sub-therapeutic doses (36.9%), excessive drug dose (3.3%) and patients failed to receive medications (56.2%). Keywords: Kidney Failure, Chronic Kidney Disease, Drug Related Problems ABSTRAK Penggunaan obat terhadap pasien gagal ginjal memungkinkan terjadinya Drug Related Problems (DRPs). DRPs merupakan setiap kejadian yang melibatkan terapi pengobatan pasien yang secara nyata atau potensial akan mempengaruhi hasil terapi yang diinginkan. Penelitian ini bertujuan untuk mengetahui Drug Related Problems (DRPs) pada pasien gagal ginjal di rawat inap RSUP Prof. DR. R. D. Kandou Manado. Penelitian ini dilakukan secara prospektif selama bulan Mei 2016 di instalasi rawat inap B RSUP Prof. DR. R. D. Kandou Manado. Penelitian ini dilakukan terhadap 27 catatan rekam medik pasien dengan penyakit gagal ginjal kronik. Hasil penelitian menunjukkan jumlah masalah terkait obat yang diketahui berpotensi mengalami DRPs yaitu indikasi tanpa terapi (3,6%), terapi tanpa indikasi (0%), pemilihan obat tidak tepat (0%), dosis sub terapi (36,9%), dosis obat berlebih (3,3%) dan penderita gagal menerima obat (56,2%). Kata kunci : Gagal Ginjal, Gagal Ginjal Kronik, Drug Related Problems
FAKTOR PENYEBAB MEDICATION ERROR DI INSTALASI GAWAT DARURAT (IGD) RUMAH SAKIT BHAYANGKARA TK.III MANADO Angkow, Leydia; Citraningtyas, Gayatri; Wiyono, Weny
PHARMACON Vol 8, No 3 (2019)
Publisher : PHARMACON

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACTPatients who enter the ECU room need fast and appropriate help, but in reality there are reports of Medication Errors in the ECU. The purpose of this research is to find out the causes factors of Medication Error in the prescribing and dispensing phase. This research is a descriptive study with prospective data collection using questionnaires. The results showed that the factors causing Medication Error on prescribing phase error included the workloads that were unbalanced of workloads and human resources (HR), interruptions which were interrupted by ringing the telephone, communication such as the incomplete writing of drug names, environmental conditions such as the temperature working area was less supportive while working, and education, namely prescription writing that does not meet the prescription completeness requirements. Factors that causes Medication Error on dispensing phase include workloads of health workers are not able to solve on the every of their own job, interruptions that interrupting working by telephone ringing, environmental conditions on the work area temperature is less supportive when working, education such as preparation of drugs that are not in recipe request, and communication, namely the communication system regarding the stock of pharmaceutical supplies in the Pharmacy Installation did not run smoothly.Keywords: Causes, Medication Error, Emergency Room, Bhayangkara Hospital.ABSTRAKPasien yang masuk IGD perlu pertolongan yang cepat dan tepat, namun kenyataannya terdapat pelaporan kejadian Medication Error di IGD. Tujuan penelitian yaitu mengetahui faktor penyebab Medication Error pada fase prescribing dan dispensing. Penelitian ini merupakan penelitian deskriptif dengan pengambilan data secara prospektif menggunakan kuisioner. Hasil penelitian menunjukkan bahwa faktor penyebab Medication Error fase prescribing meliputi beban kerja yaitu beban kerja dan SDM tidak seimbang, gangguan/interupsi bekerja yaitu terganggu dengan dering telepon, komunikasi yaitu penulisan nama obat tidak lengkap, kondisi lingkungan yaitu suhu area kerja kurang mendukung saat bekerja, dan edukasi yaitu penulisan resep yang tidak memenuhi syarat kelengkapan resep. Faktor penyebab Medication Error fase dispensing meliputi beban kerja yaitu tenaga kesehatan tidak mampu menyelesaikan sendiri setiap pekerjaan, gangguan/interupsi bekerja yaitu terganggu dengan dering telepon, kondisi lingkungan yaitu suhu area kerja kurang mendukung saat bekerja, edukasi yaitu penyiapan obat yang tidak sesuai permintaan resep dan komunikasi yaitu sistem komunikasi mengenai stok perbekalan farmasi di Instalasi Farmasi tidak berjalan lancar. Kata Kunci: Faktor penyebab, Medication Error, Instalasi Gawat Darurat, Rumah Sakit Bhayangkara

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