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Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,118 Documents
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Antidiarrheal characteristics of tempe produced traditionally and industrially in children aged 6-24 months with acute diarrhea Yati Soenarto; Sudigbia I; Herman Herman; Karmini M; Karyadi D
Paediatrica Indonesiana Vol 41 No 3-4 (2001): March 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.2.2001.88-95

Abstract

A randomized controlled double-blind clinical trial was conducted to evaluate tempe-based formulated foods fortreatment of young Indonesian children suffering from acute diarrhea. A total of 214 cases aged between 6 and 24 monthsvisiting two teaching hospitals, i.e., Sardjito hospital (n=102) in Yogyakarta and Karyadi hospital (n=112) in Semarang. Twocases from one hospital were dropped because they moved to other towns. In addition to their hospital food given duringhospitalization and daily food at home, 72 cases were given tempe-based formulated foods with tempe produced traditionally(group TT), 72 were given tempe produced industrially (group IT), whereas a control group of 68 received soybean powderformulated foods (group IS). Formula feedings were started immediately following WHO (world health organization) standardoral rehydration therapy (ORT) and continued at the patients homes for up to 90 consecutive days, including feedings duringhospitalization. Follow-up observations at patients homes were conducted twice weekly. The initial clinical characteristics ofthe cases in each group were similar. Using analysis of variance there was a non significant trend towards a shorter durationof diarrhea in the groups using tempe based formula (p=0.079). Using the t-test, the duration of diarrhea appeared to besignificantly shorter only for the group using formula with traditional tempe compared with the group using soy formula(p=0.035). The total amount of feeding formula and the total amount of calories consumed at the hospital and at home wassimilar for all three groups, although the group receiving the control formula consumed a somewhat higher amount of breastmilk (p=0.045) and a lower amount of solid food at home. Weight for age was below normal at the start of the study or afterrehydration (Z-score between -1.0 and -1.4) and approached the normal value at the end of the study for all three groups (Zscorebetween -0.51 and -0.27). The increase in Z-score was highest in the groups receiving tempe based formula (+1.0 inthe TT group and +0.9 in the IT group) and lowest in the IS group (+0.7). This implies that a tempe based formula can diminishthe duration of acute diarrhea and improve weight gain following an episode of acute diarrhea.
Serum C - Reactive Protein Level and Peripheral Blood Picture in Children with Pneumonia IGL Sidiartha; BNP Arhana; P Suwendra; Sudaryat S
Paediatrica Indonesiana Vol 38 No 3-4 (1998): March - April 1998
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (389.688 KB) | DOI: 10.14238/pi38.3-4.1998.62-7

Abstract

This cross sectional study aimed to determine the relation between serum C-reactive protein (CRP) levels and peripheral blood picture in children with bronchopneumonia, conducted at the Division of Pulmonology, Sanglah Hospital, Denpasar during 3 months (December 1996 to February 1997). Serum CRP levels, hemoglobin, leukocyte count, neutrophil count and ESR values in 30 cases between 1 month and 4.5 years (20 male and 10 female) were measured. Bronchopneumonia was mostly found in < 1 year old (67%) and with male to female ratio of 2:1. High CRP serum level (>12 microgram/ml) was found in 33% of 30 cases. Anemia was found in 37%, leukocytosis in 50%, increase segment neutrophil ratio in 30%, increase of ESR in 40% and increase of body temperature more than 38°C in 4 7% of the cases. Neutrophilia, increase of ESR and increase of body temperature were found statistically significant difference between the positive CRP and negative CRP group. Most bronchopneumonia patients in this study were probably caused by non bacteria. Neutrophilia, higher ESR and higher body temperature could be used as an indicator of bacterial infection besides the increase of serum CRP levels.
Chest x-ray findings and outcomes of children with suspected ventilator-associated pneumonia Neni Sumarni; Muhammad Sholeh Kosim; Mohammad Supriatna; Eddy Sudijanto
Paediatrica Indonesiana Vol 52 No 4 (2012): July 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.108 KB) | DOI: 10.14238/pi52.4.2012.233-8

Abstract

Background Ventilator-associated pneumonia (VAP) is anosocomial infection in patients who have received mechanicalventilation (MV), either by endotracheal intubation ortracheostomy, for more than 48 hours. YAP represents 80% ofall hospital-acquired pneumonias. VAP incidence varies from5.1 %-33.3%. The modified clinical pulmonary infection scoreis a criteria for diagnosing suspected YAP and typically includesradiographic evidence. YAP is associated with significantmorbidity and mortality.Objective To determine the relationship between chest x-rayfindings and outcomes in children Mth suspected VAP.Methods This retrospective study was held in Dr. Kariadi Hospitalfrom January - December 2010. Data was collected from medicalrecords of pediatric ICU (PICU) patients with suspected VAP.Chest x-ray findings and patient outcomes were recorded. X-rayfindings were assessed by the on-duty radiologist. Chi square testwas used for statistical analysis.Results Subjects were 30 children consisting of 14 males and 16females. Patient outcomes were 23 patients survived and 7 patientsdied. Chest x-ray findings were categorized into the followinggroups and compared to patient survivability: diffuse infiltrates76.7% (OR=0.694; P=0.532; 95% CI 0.102 to 4.717), localhedinfiltrates 13.3% (OR=4.200; P=0.225; 95% CI 0.470 t037.49),and no infiltrates 10% (OR=1.222; P=0.436; 95% CI 0.593 to0.926). None of the x-ray findings had a significant correlationto patient outcomes.Conclusion There was no significant relationship between chestx-ray findings and outcomes in children with suspected VAP.[Paediatr rndones. 2012;52:233-8].
Breastfeeding and decreased risk for childhood obesity Aspri Sulanto; Setya Wandita; Madarina Julia
Paediatrica Indonesiana Vol 52 No 1 (2012): January 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (105.562 KB) | DOI: 10.14238/pi52.1.2012.1-5

Abstract

Background Breast milk promotes infant growth and appropriateweight gain, minimizing the risk for malnutrition, and possiblyfor obesity.Objective To determine the influence of infant breastfeedingpractices on the risk for obesity in children aged 6 to 8 years.Methods We conducted a case-control study comparingbreastfeeding practices between obese and non-obese children.Subjects were selected from two elementary schools in Yogyakarta.Case subjects had body mass index (BMI)-for-age <::: + 2 SD(WHO 2007 growth reference curve). Control subjects had BMIfor-age SD between-2and+1 SD, and were matched for age andgender to the case subjects. Subjects' mothers filled questionnaireson their breastfeeding practices.Results We recruited 68 pairs of obese and non-obese subjects,4 7 (69%) pairs of boys and 21 (31 %) pairs of girls. The meanduration of breastfeeding in the obese group was shorter thanthat of the non-obese group, 12.9 months (SD 9.78) vs. 16.1months (8.39), respectively, a mean difference of 3.24 months(95% CI 0.14 to 6.32). Partially breastfed and formula-fed childrenhad significantly higher odds for obesity compared to that ofexclusively breastfed children, OR4.70 (95% CI 3.96 to 5.43) forpartial breastfeeding and 6.20 (95% CI 4.67 to 7.73) for formulafeeding. The risk for obesity also declined with longer durationsof breastfeeding.Conclusion Exclusive infant breastfeeding and longer durationof breastfeeding lowered the risk for childhood obesity in childrenaged 6-8 years. [Paediatr lndones. 2012;52: 1-5]. 
Blood glucose levels in healthy, term, appropriate for gestational age, exclusively breastfed infants Lineus Hewis; Rulina Suradi; Taralan Tambunan
Paediatrica Indonesiana Vol 45 No 1 (2005): January 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (477.125 KB) | DOI: 10.14238/pi45.1.2005.7-13

Abstract

Objective This study aimed to determine blood glucose levels ofhealthy, term, appropriate for gestational age (AGA), exclusivelybreastfed infants at the age of 6, 12, 24, 48, and 72 hours of life,and to investigate the incidence of hypoglycemia in those infants.Methods All healthy, term, AGA infants born in CiptoMangunkusumo General Hospital, Jakarta, who were exclusivelybreastfed during the recruitment period of December 2003 untilFebruary 2004, were included in this study. These infants weresubjected to blood glucose level determination at the age of 6, 12,24, 48, or 72 hours of life, and the clinical signs of hypoglycemiawere monitored.Results Two hundred and fifteen blood samples taken from 137newborns were studied. There was no incidence of hypoglycemiaobserved, whether symptomatic or asymptomatic. The range ofblood glucose levels was between 41 mg/dl and 115 mg/dl. Themeans and the standard deviations (SD) of the blood glucose lev-els of the 6-, 12-, 24-, 48- and 72-hour old infants were 59.7 (11.98)mg/dl, 64.1 (13.51) mg/dl, 65.9 (14.42) mg/dl, 67.0 (14.95) mg/dl,and 78.6 (16.51) mg/dl, respectively.Conclusions The current concern for hypoglycemia in the popu-lation of healthy, term, AGA, exclusively breastfed infants duringthe first few days of life was not proven to exist. Therefore, there isno reason to resort to prelacteal feeding in such infants
The effect of neonatal asphyxia on renal function Elly Nova Lubis; Srie Yanda; Khainir Akbar; Guslihan Dasa Tjipta; Dachrul Aldy
Paediatrica Indonesiana Vol 41 No 7-8 (2001): July 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.4.2001.175-9

Abstract

Neonatal asphyxia can cause renal perfusion and dilution disorders and also glomerular filtration abnormality. The purpose of this study was to find renal dysfunction, which caused by neonatal asphyxia. The study was performed by cross sectional for newborn babies with asphyxia based on Apgar score in the first minute. Newborn babies without asphyxia were as control. In both group, the first micturition times were recorded, total urine output in 24 hours were counted, the mean of blood urea and creatinine serum level value examined and also glomerular filtration rate. Statistical analysis has been performed by using Fisher Exact test, Student t test and Wilcoxon Rank Sum test. All of babies in the asphyxiated and non asphyxiated group had the first micturition in 24 hours after delivery. Significant difference of oliguria incidence was found in the asphyxiated group compared to the control group (p<0,05). The mean of blood urea and creatinine serum level was significantly higher in asphyxiated (p<0,05). The mean of glomerular filtration rate in the asphyxiated group was not significantly different to the control group (p>0,05). According to the degree of asphyxia we found significantly different of renal dysfunction (p<0,05). It was concluded that the asphyxia could cause the occurrence of renal dysfunction. 
Apert Syndrome Nengah Suparta; Hartono Hartono; Sunartini Sunartini
Paediatrica Indonesiana Vol 31 No 11-12 (1991): November - December 1991
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A case of Apert syndrome in a male child of 5 months old hos been reported. The diagnosis was based on the clinical appearance (phenotype) showing acrocephaly and syndactily of both hands and feet, supported by skull rontgenography and ultrasonography.The patient was the third child from normal parents, and the two other children were normal. Apert syndrome is a genetic dominant automal disease; and because there were no other sufferer from the family history, the occurrence of this syndrome has been caused by a new mutation. Symptomatic therapy such as the administration of acetazolamide for hydrocephalus and vitamin suplement to improve his general condition and even physical physiotherapy have been carried out. Genetic counselling to the couple has been provided as well.
Effect of iron ... zinc fortified milk on iron status and functional outcomes in underweight children Endang Dewi Lestari; Saptawati Bardosono; Leilani Lestarina; Harsono Salimo
Paediatrica Indonesiana Vol 49 No 3 (2009): May 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.517 KB) | DOI: 10.14238/pi49.3.2009.139-148

Abstract

Background Iron and zinc are essential micronutrients duringschool-age period. Milk could be an alternative medium formineral fortification because it is consumed frequently bychildren.Objective To evaluate the effect of iron-zinc fortified milksupplementation on iron status and functional outcomes inunderweight children.Methods 44 2 underweight subjects aged 7-10 years attending 10primary schools in Jakarta and Solo were recruited in the study.Subjects who had chronic illnesses, severe anemia, thalassemiaor cow's milk allergy were excluded. Blood samples were analyzedto determine hemoglobin, serum ferritin and serum zinc. SerumCRP was measured in sub sampled subjects (n= 60). Subjectswere randomizedly allocated to receive iron-zinc fortified milk(n = 225) and standard milk (n = 217) for six months. The fortifiedmilk will provide additional6.3 mg iron and 1.5 mg zinc per day (2feeds). The main outcomes measured were iron status, cognitivefunction, growth, physical fitness and morbidity.Results Study groups were comparable at baseline. The fortifiedmilk group had better physical fitness score and exercise durationat baseline. Both milk supplementations reduced the prevalenceof anemia and iron deficiency. Fortified milk improved the speedprocessing score (P< 0.0001), height (P<0.0001) and sittingheight (P=O.Ol) significantly.Conclusion Supplementation of milk reduces the prevalence ofanemia and iron deficiency. Zinc-iron fortified milk gives positiveimpact on cognitive performance, growth, and physical fitness.
Risk factors for hypertensive crisis in children with acute glomerulonephritis Sherly Yuniarchan; Risky Vitria Prasetyo; Ninik Asmaningsih Soemyarso; Mohammad Sjaifullah Noer
Paediatrica Indonesiana Vol 56 No 2 (2016): March 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.518 KB) | DOI: 10.14238/pi56.2.2016.101-6

Abstract

Background Hypertensive crisis occurs in 1-4% of the hypertensive pediatric population, mostly due to acute glomerulonephritis (AGN). Some factors have been suggested to affect blood pressure (BP) in children, such as age, sex, race/ethnicity, obesity, and socioeconomic status, but little is known for risk factors for hypertensive crisis in AGN.Objective To analyze the risk factors for hypertensive crisis in children with AGN.Methods Retrospectively, we studied possible risk factors for hypertensive crisis in children with AGN at Dr. Soetomo Hospital from 2007 to 2011. Hypertensive crisis was defined as systolic BP ≥180 mmHg or diastolic BP ≥120 mmHg (for children ≥ 6 years of age); and systolic and/or diastolic BP >50% above the 95th percentile (for children aged <6 years). We evaluated the demographic and clinical characteristics as potential risk factors. Statistical analysis was done with Chi-square, Fisher’s exact, and logistic regression tests. Variables with P <0.25 in the univariable analysis were further analyzed by the multivariable logistic regression model. A P value of < 0.05 was considered statistically significant.Results There were 101 children included (mean age 9.7 (SD 2.17) years), with a male-to-female ratio of 2.7:1. Hypertensive crisis occurred in 42 (41.6%) children, of whom 8 had hypertensive urgency and 34 had hypertensive emergency. Proteinuria was seen in 53 children with AGN (52.5%) and was the significant risk factor for hypertensive crisis in our subjects (OR=2.75; 95%CI 1.16 to 6.52; P=0.021). Gender, clinical profiles, ethnicity, nutritional status, blood urea nitrogen (BUN), and glomerular filtration rate (GFR) were not significant risk factors for hypertensive crisis.Conclusion Proteinuria is the significant risk factor for hypertensive crisis in children with AGN.
The occurrence of pulmonary hypertension in patients with thalassemia major Hasan Basri; Armijn Firman; Kusnandi Rusmil; Eddy Fadlyana
Paediatrica Indonesiana Vol 43 No 5 (2003): September 2003
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.461 KB) | DOI: 10.14238/pi43.5.2003.162-4

Abstract

Background The life of patients with thalassemia major dependson blood transfusions, while repeated blood transfusions may causeadverse effects such as iron deposition in various organs, includ-ing heart and lungs, which eventually increases the pulmonaryarterial pressure.Objective This study was proposed to know the occurrence ofpulmonary hypertension in patients with thalassemia major, mea-sured by echocardiography in the Thalassemia Clinic, Departmentof Child Health, Medical School, Padjadjaran University/HasanSadikin Hospital, Bandung.Methods A descriptive cross-sectional study was carried outon 30 patients with thalassemia major, aged 10-14 year-old whoreceived repeated blood transfusions. The study was conductedfrom April to May 2002. Subjects were examined right after ablood transfusion completed and the pulmonary arterial pres-sure was assessed using Doppler–echocardiography and 2-Dechocardiography.Results Twenty two out of 30 subjects showed pulmonary hyper-tension, with pulmonary arterial pressure ranged between 32.3 to46.2 mmHg. According to the age group, pulmonary hypertensionwas found in 12 out of 17 subjects aged 10-12 years old and 10out of 13 subjects aged 13-14 years old.Conclusion The occurrence of pulmonary hypertension in patientswith thalassemia major at Hasan Sadikin Hospital was 22/30 andseemed to increase with the age of the patients

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