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Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,118 Documents
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Use of pediatric logistic organ dysfunction in determining prognostic among pediatric intensive care unIt patIents Lulu Honna; Silvia Triratna; Triwani Triwani; Theodorus Theodorus
Paediatrica Indonesiana Vol 50 No 6 (2010): November 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (126.074 KB) | DOI: 10.14238/pi50.6.2010.347-50

Abstract

Background Pediatric intensive care unit is the place for caring the children \\lith higher risk of mortality, usually with multiple organ dysfunction syndrome (MODS) that can increase difficulty in detennining prognostic. Th erefore, an objective severity of illness and organ dysfunction score is needed. Pediatric logistic organ dysfunction (PELOD) score can be considered as a representative for probability of death and predicting the prognostic.Objective To determine the prognostic of patients in PICU Mohammad Hoesin hospital (RSMH), Palembang, using PELOD score.Methods An observational study was conducted from April-September 2009 among PICU patients. PELOD score was assessed in the first 24 hour. S tatistical analysis was performed using Z-Mann Whitney test, Hosmer-Lemeshow goodness-of-fit, ROC curve and survival analysis Kaplan Meier (KM).Results There were 45 (55%) boys and 36 (44%) girls with mean age 51 (SD 6 ,4 7) months. Children with MODS were 75%. Death was 37 (45%) and survival was 44 (54%) with mean length of stay was 181,92 (SE 30,23) hours. PELOD score was from 0 to 51. The best PELOD score related to death in coordinate point was 20,5 with ROC 0,862. Length of stay in grup \\lith PELOD score < 20.5 was 371.22 (SE 82.13) hours and > 20.5 was 93 (SE 17.48) hours (log rank P=0.000). S urvival function KM showed that the higher PELOD score, the shorter length of stay in PICU.Henceforth, the higher probability prediction of mortality.Conclusion PELOD score can be used as a prognostic predictor of mortality among PICU patients in Mohammad Hoesin Hospital (RSMH), Palemhang.
Third trimester maternal 1,25-dihydroxyvitamin D and neonatal birth weight Yusrawati Yusrawati; Meldafia Idaman; Nur Indrawati Lipoeto
Paediatrica Indonesiana Vol 57 No 2 (2017): March 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (878.198 KB) | DOI: 10.14238/pi57.2.2017.67-9

Abstract

AbstractBackground The main cause of neonatal mortality is low birth weight. Active form of vitamin D (1,25-dihydroxyvitamin D) increase the efficiency of calcium and phosphorous absorption in intestinal. Deficiency 1,25-dihydroxyvitamin D in pregnant woman was hipothesized relates with low birth weight in neonate.Objective To determine the relationship between maternal 1,25-dihydroxyvitamin D level and neonatal birth weight.Methods This was an observational study with cohort design to 47 women in the third trimester pregnancy. This study was cond  ucted on August to December 2014. Subjects were taken from Ibu dan Anak Hospital, Padang, West Sumatera. Maternal blood from antecubital vein was examined for 1,25-dihydroxyvitamin D concentration using enzyme-linked immunosorbent assay (ELISA). Neonatal birth weights were measured right after delivery.  Data were analyzed by Pearson’s correlation and linear regression tests.Results A positive correlation was found between maternal 1,25-dihydroxyvitamin D level and neonatal birth weight (R=0.910; R2=0.821; P=0.000). The 1,25-dihydroxyvitamin D level had an 82.1% contribution to the baby’s birth weight, while other factors not assessed in this study had less of an effect.Conclusion There was positive correlation between maternal 1,25-dihydroxyvitamin D levels in the third trimester of pregnancy and neonatal birth weight
Enteral Vs. Parenteral Nutrition: Advantages and Disadvantages Duna Penn
Paediatrica Indonesiana Vol 36 No 5-6 (1996): May - June 1996
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi36.5-6.1996.91-7

Abstract

The goal of nutritional support is to maintain or replete lean body mass, to support host defense mechanisms, to avoid specific nutritional deficiencies, and in gen­eral to improve clinical outcome in a malnourished patient or in at risk to develop mal- nourishment. Nutritional support can be instituted by enteral or parenteral route; each has its advantages and disadvantages. Which mode of delivery is chosen much depends on the clinical condiron of the patient. In general enteral route is preferred, since it is more physiological; however, in certain condition where enteral route is either impossible or dangerous, parenteral nutrition can be used as an alternative which might be life sav­ing. The advantages and disadvantages of nutritional support delivery is discussed briefly and comprehensively.The goal of nutritional support is to maintain or replete lean body mass, to support host defense mechanisms, to avoid specific nutritional deficiencies, and in gen­eral to improve clinical outcome in a malnourished patient or in at risk to develop mal- nourishment. Nutritional support can be instituted by enteral or parenteral route; each has its advantages and disadvantages. Which mode of delivery is chosen much depends on the clinical condiron of the patient. In general enteral route is preferred, since it is more physiological; however, in certain condition where enteral route is either impossible or dangerous, parenteral nutrition can be used as an alternative which might be life sav­ing. The advantages and disadvantages of nutritional support delivery is discussed briefly and comprehensively.
Determinants of infant care practices in Minangkabau ethnic Masruli Masruli; Hari Basuki
Paediatrica Indonesiana Vol 52 No 5 (2012): September 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.964 KB) | DOI: 10.14238/pi52.5.2012.280-3

Abstract

Background Child care practices are important for growthand development, and are influenced by cultural determinants.Indicators of infant care practices have not been determined forthe Minangkabau ethnic group.Objective To determine indicators of infant care among aMinangkabau ethnic community.Methods A cross􀁈sectional study was done in Solok, WestSumatera, a region populated by largely Minangkabau ethnicgroups. Infant feeding care (IFC), infant health care (IHC), infantclean care (ICC), and infant psychosocial stimulation care (IPSe)were the components of infant care used as indicators. Data onthese four components were obtained through interviews withparents and direct observation. A score was assigned to eachcomponent. We used the confirmatory factors analysis (CFA)method to determine whether the indicators were valid in thestudied population.Results We enrolled 417 infants in the study, v.ith a mean age of8.7 months, and 51.6% were female. IFC scores were fairin 72.7%,high in 20.4%, and low in 6.7%. IHC scores were poor in 25.7%,fair in 58.8%, and good in 15.5%. ICC scores were poor in 0.7%,fair in 42.2%, and good in 58.1 %. IPSC scores were poor in 10.6%,fair in 84.9%, and high in 4.5%. On CFA, ICC contributed least tothe indicator model (A: 0.17). ICC and IPSC had fair contributionsto the model (A: 0.5 and 0.47, respectively). Goodness of fit of themodel was good (P>0.05). Root mean square error approximationwas <0.08 and goodness of fit index was >0.9.Conclusions Infant clean care was the most significant contributorto the infant care practice indicator in the Minangkabau ethniccommunity. Similar studies need to be done in other Indonesianethnic groups. [Paediatr Indones. 2012;52:280,3].
Risk of nutritional status on diarrhea among under five children Wiliam Jayadi Iskandar; I wayan Sukardi; Yati Soenarto
Paediatrica Indonesiana Vol 55 No 4 (2015): July 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.677 KB) | DOI: 10.14238/pi55.4.2015.235-8

Abstract

Background Diarrhea is still the leading cause of children’s mortality worldwide and the main cause of malnutrition. Meanwhile, malnourished children are proven to have more severe, prolonged, and frequent episodes of diarrhea, making them a vicious circle.Objective To investigate the risk of nutritional status on diarrheal severity and duration as well as length of hospital stay.Methods We conducted a cross sectional study involving 176 under five children who admitted to Mataram Province Hospital with acute diarrhea since January until December 2013. We analyzed data using logistic regression model.Results Most subjects were infants (median 12 months, range 1-53), male (56.8%), well-nourished (85.8%), admitted with acute watery diarrhea (97.2%), mild-to-moderate dehydration (71.6%), diarrhea severity score ≥11 (74.4%), duration of diarrhea ≤7 days (96.6%), and length of stay <5 days (73.3%). Logistic regression model indicated significant risk of nutritional status on length of hospital stay (adjusted OR 2.09, 95% CI 1.06 to 6.38), but neither diarrheal severity (adjusted OR 1.03, 95% CI 0.38 to 2.80) nor duration of diarrhea (adjusted OR = 1.17, 95% CI = 0.13 to 10.89) indicated significant risks. However, malnourished children had more severe (76% versus 74.2%) and longer duration (4% versus 3.3%) of diarrhea than well-nourished children.Conclusion Nutritional status is the risk for length of hospital stay in under-five children admitted with acute diarrhea. [
Association between neutropenia and death rate of bacterial neonatal sepsis Elly Noer Rochmah; Ekawaty Lutfia Haksari; Sri Mulatsih
Paediatrica Indonesiana Vol 48 No 5 (2008): September 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (102.474 KB) | DOI: 10.14238/pi48.5.2008.284-7

Abstract

Background Neonatal sepsis remains a crucial problem with highmorbidity and mortality. Not less than four million neonates dieevery year, 99% of which occur in developing countries withinfection as the main cause (36%) of death. The prognosticfactors of bacterial neonatal sepsis vary. However the death ratein neonatal sepsis with neutropenia is suspected to be higher thanthat in non-neutropenic condition.Objectives The purpose of this study was to identify whetherneutropenia would increase the death risk of bacterial neonatalsepsis.Methods We conducted a retrospective cohort study. Subjectswere neonates at Instalasi Maternal Perinatal (IMP) of Dr. SardjitoHospital in Yogyakarta who met the eligibility criteria. Duringthe five-year period Qanuary 2002- January 2007), out of 1821cases of suspected neonatal sepsis, 365 (16.7%) were found tohave bacterial cause in the culture of body's fluid (blood, urine,and cerebrospinal). Out of these 16.7% patients suffering fromneutropenia, 39.6% patients died, whereas 9.1 o/o patients weresurvive [RR 4.72, (95% CI: 2.49 to 8.93), P < 0.01].Conclusion Neonates suffering bacterial sepsis with neutropeniahad death risk 4.7 times higher than those who did not haveneutropenia.
Limitations of the Indonesian Pediatric Tuberculosis Scoring System in the context of child contact investigation Rina Triasih; Stephen M. Graham
Paediatrica Indonesiana Vol 51 No 6 (2011): November 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.6.2011.332-7

Abstract

tuberculosis (TB) was developed to address the problem of overdiagnosis. The implementation of this scoring system in children who have household TB contacts has not been evaluated.Objective To evaluate the performance of the Indonesian pediatric tuberculosis scoring system in the context of contact investigation.Methods A cross-sectional study was conducted in the Yogyakarta municipality, between August 2010 and March 2011. Subjects were children under the age of 15 years, living in the same house with an adult who had pulmonary TB. Subjects underwent history taking, physical examinations, tuberculin skin tests (TST) and chest X-rays. Sputum smear was performed in symptomatic children. We compared outcomes of the Indonesian pediatric TB scoring system to that of rigorous clinical assessment.Results A total of 146 eligible children of 82 source cases were recruited into the study. Sixty-eight (47%) children had positive TST tuberculin skin tests. Using the scoring system, 47% of the subjects were diagnosed to have TB disease, while only 10% were diagnosed with TB using rigorous clinical assessment. With rigorous clinical assessment, 40% of the subjects were diagnosed as having latent TB infection (LTBI), while none of the subjects were diagnosed as LTBI using the scoring system.Conclusion The use of the Indonesian pediatric TB scoring system in children with household TB contact may lead to overdiagnosis of TB disease.
Association of geohelminths infection and asthma in elementary school children in Kalibaru, North Jakarta Jaya A Effendi; Mardjanis Said; Partini P Trihono
Paediatrica Indonesiana Vol 50 No 2 (2010): March 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.2.2010.80-5

Abstract

Background Asthma inflammation process and geohelminthinfection have the same immune response. Epidemiological studiesin developed countries show the increased asthma prevalenceand decreased geohelminth infection, while developing countriesusually have low asthma prevalence but high geohelminthinfection.Objectives To determine asthma proportion in children withgeohelminth infection and relationship between asthma andgeohelminth prevalence of elementary school students in NorthJakarta.Method A cross sectional study was done in February 2009 at anElementary School in North Jakarta. Asthma was diagnosed usingISAAC questionnaire which was answered by parents. We didfecal analysis using ether formaline test to establish geohelminthinfection.Results The proportion of students with asthma was 11.5%(33 of 286 children). Most of them were male, aged 6-10 yearsold, and well nourished. Geohelminth infection was foundin 71.9%of the students. Most of children with geohelminthinfection were male (55%), aged 6-10 years old (63%), and wellnourished (64%). Proportion of asthma in children with andwithout geohelminth infection is 12.6% and 8.8%, respectively.Geohelminth infection consisted of ascariasis (80%), trichuriasis(39%), and ankylostomiasis (9%). There was no significantrelationship between asthma and geohelminth infection(P=0.357), nor between asthma and ascariasis (P=0.202), asthmaand trichiuriasis (P=0.133).Conclusions The occurrence of asthma in children withgeohelminth infection is 12.6% and there is no difference ofasthma incidence among children with or without geohelminthinfection.
Prevalence of Heart Disease of Elementary Schoolchildren in a Well-To-Do Population Group, Jakarta 1973 Maemunah B. Affandi; L.A. Tamaela; R. Widodo Talogo
Paediatrica Indonesiana Vol 19 No 1-2 (1979): January - February 1979
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi19.1-2.1979.41-6

Abstract

This study, using as the screening method the presence of heart murmurs, yielded only 28 suspected cases of heart disease. Eight out of the 28 cases were definitely heart disease cases. Two with acquired heart disease (mitral insufficiency) and six with congenital heart disease (4 ventricular septal defect, one atrial septal defect, one patent ductus arteriosus). Growth retardation was observed in 7 children regarding their heights and weights which were less than the lower limit for the normal heights and weights for schoolchildren in Jakarta.
Neutrophil, TLR2, and TLR4 expression in newborns at risk of sepsis Ari Yunanto; Agustina Tri Endharti; Aris Widodo
Paediatrica Indonesiana Vol 53 No 3 (2013): May 2013
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (297.282 KB) | DOI: 10.14238/pi53.3.2013.132-7

Abstract

Background There is increasing evidence that toll-like receptors (TLR) play a key role in the mediation of systemic responses to invading pathogens during sepsis. Saliva is an important body fluid for detecting physiological and pathological conditions of the human body. Neutrophils are participants in the acute response against pathogens in many tissues, and their influx into the oral cavity may occur at any time.Objective To compare mean neutrophils and the expression of TLR2 and TLR4 in saliva and blood of newborns at risk for sepsis to those of healthy newborns.Methods This cross-sectional study was conducted from July to December 2011 in the Division of Neonatology, Department of Child Health, Ulin General Hospital, Lambung Mangkurat University Medical School, Banjarmasin. Case subjects were newborns with sepsis risk factors (30 infants), while 30 healthy infants were in the control group. Saliva and blood specimen examinations were performed in the Biomedical Laboratory of Brawijaya University Medical School, Malang. We used T-test for statistical analyses.Results From saliva specimens, mean neutrophils were significantly higher in the case group than in the control group [14.43 (SD 12.21) % vs. 5.63 (SD 6.78) %, respectively, (P=0.021)]. In addition, mean TLR2 and mean TLR4 saliva levels were significantly higher in the case group than in the control group [TLR2: 64.97 (SD 26.42) % vs. 40.06 (SD 6.23) %, respectively, (P=0.011); TLR4: 1.5 (SD 1.61) % vs. 0.57 (SD 0.53) %, respectively, (P=0.044)]. From blood specimens, mean neutrophils were also significantly higher in the case group than in the control group [1.09 (SD 0.61)% vs. 0.21 (SD 0.09)%, respectively, (P=0.000)]. Similarly, mean blood TLR2 and TLR4 levels were significantly higher in the case group than in the control group [TLR2: 92.51 (SD 5.51) % vs. 81.74 (SD 11.79) %, respectively, (P=0.003); TLR4: 0.71 (SD 1.42) % vs. 0.12 (SD 0.06) %, respectively, (P=0.000)].Conclusion There are significant increases in neutrophils, as well as neutrophil expression of TLR2 and TLR4 in the saliva and blood from newborns with sepsis risk factors compared to those of healthy newborns. [Paediatr Indones. 2013;53:132-7.]

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