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Paediatrica Indonesiana
Published by Ikatan Dokter Anak Indonesia
ISSN : 00309311     EISSN : 2338476X     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.
Arjuna Subject : -
Articles 2,118 Documents
 40   41   42   43   44 
Neonatal Tetanus H. Tjandra; M. Munir
Paediatrica Indonesiana Vol 18 No 9-10 (1978): September - October 1978
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (203.983 KB) | DOI: 10.14238/pi18.9-10.1978.263-8

Abstract

Analysis of 108 cases of Neonatal Tetanus by using a scoring system (Tjandra et al., 1974) revealed that 18 patients belonged to Grade I with a mortality rate of 5.6%; 43 belonged to Grade II with a mortality nate of 58.1%; and 47 belonged to Grade III with 91.5% mortality. The differences of mortality between the 3 groups are statistically significant. Mortality rate of 1973 was the lowest (50%) compared to that of 1972 (75%); 1974 (72.2%) and 1975 (61.4%). However, the number of patients belonging to Grade I in 1973 was the highest, 36.4%; whereas that of 1972 was 16.7%; 1974 was 11.1% and 1975 was 9.1 %. Classification of severity in Neonatal Tetanus is therefore, not only important for selecting a "treatment of choice" by comparing mortality rates of those having the same grade of severity, but may be also very useful in determining the method of treatment for different levels of severity.
Influence of socioeconomic status on the association between low weight at birth and stunted growth or overweight in rural and urban Indonesian prepubertal children Madarina Julia; M. M. van Weissenbruch; H. A. Delemarre-van de Waal; Achmad Surjono
Paediatrica Indonesiana Vol 48 No 4 (2008): July 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi48.4.2008.214-9

Abstract

Background Low birth weight (LBW) has been associated with in-creased risk for both stunted growth andand overweight later in life.Objective To assess relative contribution of LBW on the preva-lence of stunted growth or overweight in rural and urban Indo-nesian children in Indonesia.Methods This is a cross-sectional survey of 2 833 (1125 rural and1708 urban) school-aged prepubertal children. Each child had dataon age, sex, stature, BMI (body mass index) and birth weight.Results Compared to the urban population, the prevalence ofstunted growth was significantly higher in the rural, i.e. 16.3 vs.32.7%, P<O.OOl. However, there was no significant difference iinn the prevalence of LBW in the two communities. While overall,stunted children were more likely to be born with LBW, OR 1.80(95%CI 1.31; 2.47), P<O.OOl. After stratifying data into rural andurban residences, the contribution of LBW on the risk of stuntedgrowth appeared to be only significant in the urban population, OR2.42 (95%CI 1.59; 3.68), P<O.OOl. In the rural, similar proportionsof LBW were found in stunted and not stunted children. Test of in-teraction showed that this difference in OR was significant, the ratioof OR 1.88 (95%CI 1.11; 3.17), P=0.02. We observed no associationbetween LBW and overweight.Conclusions In rural area, LBW is not an important contributorfor stunted growth, while in urbanarea LBW is an important riskfactor for stunted growth. As there is no significant difference inthe prevalence of LBW between the two communities, the dif-ference in the prevalence of stunted growth is more likely to beassociated with different pattern of post-natal growth
Nutritional status and physical activity of childhood leukemia survivors Conny Tanjung; Johannes Bondan Lukito; Prima Dyarti Meylani
Paediatrica Indonesiana Vol 54 No 2 (2014): March 2014
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.806 KB) | DOI: 10.14238/pi54.2.2014.67-72

Abstract

Background Acute lymphoblastic leukemia (ALL), the mostcommon malignancy of childhood, has an overall cure rate ofapproximately 80%. Long-term survivors of childhood ALL areat increased risk for obesity and physical inactivity that may leadto the development of diabetes, dyslipidemia, metabolic syndrome,as well as cardiovascular dis eases, and related mortality in theyears following treatment.Objective To evaluate the physical activity and the propensityfor developing obesity longer term in ALL survivors.Methods This retrospective cohort study included all ALLsurvivors from Pantai Indah Kapuk (PIK) Hospital. We assessedtheir physical activity and nutritional status at the first time ofALL diagnosis an d at the time of interview.Results Subjects were 15 ALL survivors aged 7 to 24 years. Themedian fo llow up time was 6.4 years (range 3 to 10 years). Only2 out of 15 survivors were overweight and n one were obese.All survivors led a sedentary lifestyle. Most female subjectshad increased BMI, though most were not overweight/obese.Steroid therapy in the induction phase did not increase the riskof developing obesity in ALL survivors.Conclusion Lon g-term survivors of childh ood ALL do not meetphysical activity recommendations according to the CDC (Centersfor Disease Control). Howevei; steroid therapy do not seem tolead to overweight/obesity in ALL survivors.
Incidence and factors associated with mortality of neonatal sepsis I Made Kardana
Paediatrica Indonesiana Vol 51 No 3 (2011): May 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.172 KB) | DOI: 10.14238/pi51.3.2011.144-8

Abstract

Background Neonatal sepsis is one of the major causes of mortality and long term morbidity in neonates, particularly in premature and low birth weight infants. The incidence of neonatal sepsis varies from 1 to 4 in 1000 live births in developed countries and 10 to 50 in 1000 live births in developing countries. The mortality rate of neonatal sepsis remains high, especially in developing countries.Objective To describe the incidence, mortality rate, and factors associated 'With mortality in neonatal sepsis in Sanglah Hospital, Denpasar.Methods A retrospective, cohort study was conducted in the Perinatology Ward, Department of Child Health, Sanglah Hospital, Denpasar, Bali from January to December 2008. One hundred thirty􀁄eight patients 'With neonatal sepsis were enrolled in this study. Patients' characteristic data were collected including sex, mode of delivery (spontaneous, non􀁄spontaneous), condition at birth (vigorous, asphyxic), gestational age (premature, full tenn), birth weight «2500 grams, > 2500 grams), and sepsis classifica􀁄tion (early onset sepsis, late onset sepsis). Outcomes were grouped into alive and dead.Results A total of 138 cases of neonatal sepsis were reviewed, 59.4% of whom were boys, 63.0% spontaneously delivered,39.1 % asphyxic, 53.6% 'With low birth weight, 50.7% premature, and84.8% with early onset sepsis. The incidence of neonatal sepsis was 5% of babies admitted, 'With a mortality rate of 28.3%. Low birth weight and prematurity were significantly associated withmortality in neonatal sepsis (RR8.4, 95% CI 2.4 to 29.0, P = 0.001 and RR3.4, 95% ClI.O to 11.0, P 􀀂 0.042, respectively). Conclusion The incidence of neonatal sepsis in Sanglah Hospital was 5% of babies admitted, with a mortality rate of 28.3%. Low birth weight and prematurity were significantly associated with mortality in neonatal sepsis. 2011;51:144-8].
Correlation between serum zinc level and simple febrile seizure in children Lusiana Margaretha; Nurhayati Masloman
Paediatrica Indonesiana Vol 50 No 6 (2010): November 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (127.763 KB) | DOI: 10.14238/pi50.6.2010.326-30

Abstract

Background Simple febrile seizure is the most common form of seizure which occurs during childhood period. Zinc, one of microelements in human body, has an important role in central nervous system formation.Objectives To find out serum zinc level in simple febrile seizure patients and the correlation between serum zinc level and simplefebrile seizure.Methods This cros-sectional study was conducted at R. D. Kandoll Hospital, Tingkat III Teling Hospital and Pancaran Kasih Hospital, Manado on April 5th - June 15th, 2009.Results Diagnosis for febrile v.ithout seizure patients were 12 with acute respiratory tract infection (ARl), 6 dengue hemorrhagic fever (DHF), 6 acute diarrhea v.ithout dehydration and 1 ARI with DHF, while simple febrile seizure were 19 ARI, five acute diarrhea v.ithout dehydration and one ARI v.ith DHF. There were no significant differences of age, gender and nutritional status in two groups. F amily history of febrile seizure, febrile period and body temperature in two groups were significantly different. Mean serum zinc level in simple febrile seizure and febrile v.ithout seizure were 8.83 μmol/L and 13.72 μmol/L, respectively. Mean serum zinc level in simple febrile seizure children with seizure period <5 minutes, 5-<10 minutes and 10-15 minutes were 10.27 (SD 0.25)  μmol/L, 9.02 (SD 0.81) ) μmol/L and 6.90 (SD) 0.98 μmol/L, respectively.Conclusions There is correlation between serum zinc level and simple febrile seizure. The lesser serum zinc level, the longer duration of seizure occurs in simple febrile seizure.
Effect of fresh blood transfusion in the treatment of sclerema neonatorum Erwin Sarwono; F. X. Marseno; R. Kwari Satjadibrata; A. R. Polanunu
Paediatrica Indonesiana Vol 13 No 4 (1973): April 1973
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi13.4.1973.120-33

Abstract

There is still confusion in the proper knowledge of Sclerema. At least 3 different conditions with induration of the subcutaneous fat in the neonatal period and in the first months of life exist which are called Sclerema (Djojodiguno, 1965; Nelson, 1959). In this paper, sclerema neonatonun is defined a.s a condition characterized by a diffuse rapidly spreading, non-edematous, tallow-like hardening of the subcutaneous tissue of infants in the first weeks of life. The skin of the involved areas cannot be picked up and the subcutaneous tissue seems fixed on to the subjacent muscles and bones (Hughes and Hammond, 1948).
Clinical features and specific lgE in babies and children with cow's milk allergy Syawitri P. Siregar; Ida Mardiati; Arwin P. Akib
Paediatrica Indonesiana Vol 39 No 3-4 (1999): March - April 1999
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi39.3-4.1999.83-7

Abstract

A discriptive prospective study was done on babies & children not olderthan 3 years of age who came to Pediatric Allergy & Immunology Clinic, Medical School, University of Indonesia - Cipto Mangunkusumo Hospital, Jakarta, during the period of April I 996-March I 997. Screening test included interview, physical examination elimination and open provocation. The aim of the study was to determine clinical features and specific lgE of babies and children with cow's milk allergy (CMA). Among 541 patients, 18 were diagnosed as CMA. The most common clinical symptoms was cronic and recurrent cough (CFC), while only 5 patients were suffering from diarrhea. Specific IgE examination gave positive results on 7 patients, skin tests were positive in 11 patients, and increased total lgE count were found in 13 patients. All CMA patients had family history of atopies.
Risk factors for cefotaxime resistance in children with pneumonia Anak Agung Made Sucipta; Ida Bagus Subanada; Samik Wahab
Paediatrica Indonesiana Vol 52 No 5 (2012): September 2012
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.291 KB) | DOI: 10.14238/pi52.5.2012.255-9

Abstract

Background Pneumonia is a health problem in developingcountries, often caused by bacterial agents. The 'Widespreaduse of cefotaxime, a third􀁒generation of cephalosporin, may leadto increased incidence of resistance to this antibiotic. Severalstudies have reported on risk factors associated v.ith resistanceto cefotaxime.Objective To identify risk factors for cefotaxime resistance inchildren 'With pneumonia.Methods We performed a case􀁒control study at Sanglah Hospitalbetween January 2006􀁒December 2010. The case group includedchildren with blood culture􀁒positive pneumonia and resistanceto cefotaxime by sensitivity test. The control group was selectedfrom the same population as the case group, but the bacteriaisolated from these subjects were sensitive to cefotaxime. Wetested the folloMng risk factors for resistance to cefotaxime:age :53 years, microorganism species, history of antimicrobialuse, and history of hospitalization within the prior 3 months.Chi square test and logistic regression analysis were performedto determine any associations between the four potential riskfactors and resistance to cefotaxime. A P<0.05 was consideredto be statistically significant.Results Univariate analysis showed that the risk factors forresistance to cefotaxime were history of antimicrobial use in theprior 3 months (OR 2.79; 95%CI 1.40 to 5.55; P􀁓O.OOI) andhistory of hospitalization Mthin the prior 3 months (OR 5.57;95%CI 1.95 to 15.87; P=<O.OOOl). By multivariate analysis,risk factors associated Mth resistance to cefotaxime were historyof antimicrobial use in the prior 3 months (OR 2.4; 95%CI 1.18to 4.86; P=0.015), history of hospitalization within the prior 3months (OR 4.7; 95%CI 1.62 to 13.85; P􀁓0.004), and historyof breast feeding for less than 2 months (OR 2.3; 95%CI 1.0 to5.4; P􀁓0.042).Conclusion History of antimicrobial use and history ofhospitalization within the prior 3 monthsweresignificantrisk factors for resistance to cefotaxime in children Mth pneumonia.[Paediatr Indanes. 2012;52:255-9].
Melatonin level and sleep disorders in adolescents Andre Inigo; Hesti Lestari; Nurhayati Masloman; Julius Lolombulan
Paediatrica Indonesiana Vol 55 No 4 (2015): July 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (236.981 KB) | DOI: 10.14238/pi55.4.2015.215-8

Abstract

Background Sleep disorder is defined as a disturbance in the quality and time of sleep. Decreased melatonin levels have been noted in people with sleep disorders. Melatonin is a neurohormone, produced mainly by the pineal gland, as well as a small part of the retina. Its function is to maintain normal circadian rhythms and it is related to sleep regulation in humans.Objective To assess for a relationship between melatonin levels and sleep disorders in adolescents.Methods We conducted a cross-sectional study on students of two secondary schools in Tuminting, Manado, North Sulawesi, from May to June 2013. Subjects were obtained by consecutive sampling for a total of 44 adolescents aged 12-15 years. Subjects filled questionnaires, underwent wrist actigraphy, and provided blood specimens for examination of melatonin levels. We used descriptive and logistic regression analyses to assess for relationships between variables.Results Thirty (68.2%) subjects experienced sleep disorders. There was a significant association between decreased melatonin levels and the higher incidence of sleep disturbances (P = 0.02).Conclusion There is a correlation between melatonin levels in adolescents with sleep disorders. Decreased melatonin levels are associated with sleep disorders.
Survival and prognostic factors of childhood acute lymphoblastic leukemia Emelyana Permatasari; Endang Windiastuti; Hindra lrawan Satari
Paediatrica Indonesiana Vol 49 No 6 (2009): November 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (969.198 KB) | DOI: 10.14238/pi49.6.2009.365-71

Abstract

Background The treatment protocols of childhood acutelymphoblastic leukemia (ALL) have been improved.Some factors such as age, sex, and nutritional status couldinfluence therapy outcome.Objective To study the survival differences among age, sex,and nutritional status groups in childhood ALL.Methods A retrospective Kaplan-Meier survival analysis ofchildhood ALL was performed in Cipto MangunkusumoHospital since January 1st 1998 until December 31st 2003.We excluded patients aged < 1 years, those with L3 subtype,patients with modified chemotherapy protocol, or withincomplete data.Results A total of 252 patients were analyzed. Overallsurvival of 1-2 year old, > 2-< 10 year old, and 10-18 yearold subjects were 57% (95% CI 38 to 76%), 47% (95% CI40 to 54%), and 35% (95% CI 21 to 49%) respectively (P< 0.05). Five-year -event-free survival (EFS) of 1-2 year old,> 2-< 10 year old, and 10-18 year old subjects were 40%,40%, and 16%, respectively (P <0.05). Overall survival ofmale and female subjects were 46% and 53% respectively(P >0.05). Five-year-EFS of male and female subjects were29% and 45% (P >0.05). Overall survival of well-nourished,undernourished, and malnourished patients were 42%50%and 57% respectively (P >0.05). The five-year-EFS of wellnourished, undernourished, and malnourished subjects were33%,38%, and 51%, respectively (P >0.05).Conclusion Childhood ALL aged 1-2 years had the highestsurvival rate while those of 10-18 year old had the lowest. Therewere no survival rate differences between sex and nutritionalstatus groups.

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