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INDONESIA
Jurnal Penelitian Kesehatan Suara Forikes
Published by Forum Ilmiah Kesehatan
ISSN : 20863098     EISSN : 25027778     DOI : -
Core Subject : Health,
Journal of Health Research "Forikes Voice" is a medium for the publication of articles on research and review of the literature. We accept articles in the areas of health such as public health, medicine, nursing, midwifery, nutrition, pharmaceutical, environmental health, health technology, clinical laboratories, health education, and health popular.
Arjuna Subject : -
Articles 1,733 Documents
Dampak Kesehatan Mental Pada Tenaga Kesehatan Dan Pasien di ICU Dengan Covid-19: A Literature Review Nor Rahayu; Nurlaila Fitriani; Supratman Supratman
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf13208

Abstract

The increase in Covid-19 has had a considerable impact in the health service sector, including in the Intensive Care Unit. The impact felt by health workers and patients in the Intensive Care Unit, is not only in terms of physical, but also psychological. Psychological responses are felt differently. The purpose of this literature review is to identify more deeply, the impact of mental health on health workers and patients with Covid-19 in the ICU. Search articles using three databases, namely PubMed, Sciencedirect, Willey Online Library. Based on the search results, 324 articles were found, and 9 of them according to the inclusion and exclusion criteria were used. It was concluded that Covid-19 had a negative impact on the mental health of health workers and patients with Covid-19 in the Intensive Care Unit.Keywords: Covid-19; mental health; health workers; patient; Intensive Care UnitABSTRAK Peningkatan Covid-19 memberi dampak cukup besar di bidang pelayanan kesehatan termasuk di Intensive Care Unit. Dampak yang dirasakan oleh tenaga kesehatan dan pasien di Intensive Care Unit, tidak hanya dari segi fisik, tetapi juga psikologis. Respon psikologis yang dirasakan berbeda-beda. Tujuan literature review ini adalah untuk mengidentifikasi secara lebih dalam, dampak kesehatan mental pada tenaga kesehatan dan pasien dengan Covid-19 di ICU. Pencarian artikel menggunakan tiga database, yaitu PubMed, Sciencedirect, Willey Online Library. Berdasarkan hasil pencarian didapatkan 324 artikel, dan 9 di antaranya sesuai dengan kriteria inklusi dan ekslusi digunakan. Disimpulkan bahwa Covid-19 berdampak buruk pada kesehatan mental tenaga kesehatan dan pasien dengan Covid-19 di Intensive Care Unit.Kata kunci: Covid-19; kesehatan mental; tenaga kesehatan; pasien; Intensif Care Unit
Konsumsi Daun Bayam untuk Meningkatkan Kadar Hemoglobin Pada Ibu Hamil Misrawati Misrawati; Nur Asmi; Marliah Marliah
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf.v13i2.1867

Abstract

 Spinach leaves are rich in iron content. The purpose of this study was to determine the effect of consuming spinach leaves on increasing Hb levels in pregnant women at Antang Raya Makassar Health Center. The design of this research was one group pretest-posttest. The research subjects were 15 pregnant women in the second trimester at the Antang Raya Health Center who were selected by purposive sampling technique. Hb level data was measured digitally using the Hemoglobin Testing System Quick-Check. Data were analyzed descriptively followed by paired sample t-test. The results of the analysis showed that the average Hb level of pregnant women before consuming spinach leaves was 2.00 g/dl and after that was 2.67 g/dl. The p value was 0.000 so it can be concluded that there is a difference in Hb levels between before and after consuming spinach leaves.Keywords: spinach leaves; hemoglobin; pregnant mother ABSTRAK Daun bayam kaya akan kandungan zat besi. Tujuan penelitian ini adalah mengetahui pengaruh konsumsi daun bayam terhadap peningkatan kadar Hb pada ibu hamil di Puskesmas Antang Raya Makassar. Rancangan penelitian ini adalah one group pretest-posttest. Subyek penelitian adalah 15 ibu hamil trimester II yang di Puskesmas Antang Raya yang dipilih dengan teknik purposive sampling. Data kadar Hb diukur secara digital menggunakan Hemoglobin Testing System Quick-Check. Data dianalisis secara deskriptif dilanjutkan dengan paired sample t-test. Hasil analisis menunjukkan bahwa rerata kadar Hb ibu hamil sebelum mengonsumsi daun bayam adalah 2,00 g/dl dan sesudahnya adalah 2,67 g/dl. Nilai p adalah 0,000 sehingga disimpulkan bahwa ada perbedaan kadar Hb antara sebelum dan sesudah mengonsumsi daun bayam.Kata kunci: daun bayam; hemoglobin; ibu hamil
Aplikasi Teori Comfort dapat Meningkatkan Kenyamanan Bayi dengan Masalah Keperawatan Disorganisasi Perilaku Nyimas Sri Wahyuni; Yeni Rustina; Defi Effendi
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf.v13i2.1777

Abstract

The action procedure for low birth weight (LBW) infants during treatment causes the baby to respond to nursing problems with disorganization of infant behavior. This study aims to describe the approach of Kolcaba's Comfort theory in meeting the disorganized needs of infants' behavior. This study method was carried out by case reports. Nursing interventions were carried out with a comfort nursing process, by creating physical, psychospiritual, sociocultural and environmental comfort for the baby. Based on the evaluation, it was concluded that three out of five infants with LBW were in a transcendence comfort level which indicated that the infants felt comfortable after the intervention. Kolcaba's Comfort theory can be applied in neonatal care because the care is carried out holistically and is able to create baby comfort.Keywords: low birth weight babies; baby behavior; convenience theory ABSTRAK Prosedur tindakan untuk bayi berat lahir rendah (BBLR) selama dirawat menyebabkan bayi berespon dengan masalah keperawatan disorganisasi perilaku bayi. Studi ini bertujuan untuk menggambarkan pendekatan teori Comfort Kolcaba dalam memenuhi kebutuhan disorganisasi perilaku bayi. Metode studi ini dilakukan dengan laporan kasus. Intervensi keperawatan dilakukan dengan proses keperawatan Comfort, dengan menciptakan kenyamanan bayi secara fisik, psikospiritual, sosiokultural dan lingkungan. Berdasarkan evaluasi disimpulkan bahwa tiga dari lima bayi dengan BBLR berada dalam tingkat kenyamanan transcendence yang menunjukkan bahwa bayi merasa nyaman setelah dilakukan intervensi. Teori Comfort Kolcaba dapat diterapkan dalam perawatan neonatal karena perawatan dilakukan secara holistik dan mampu menciptakan kenyamanan bayi.Kaca kunci: bayi berat lahir rendah; perilaku bayi; teori kenyamanan
Gambaran Personal Hygiene dan Sanitasi Industri Rumah Tangga Produksi Tahu di Wilayah Kapas, Kabupaten Bojonegoro Nazahah Hunafa; Narwati Narwati; Winarko Winarko
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf.v13i2.1679

Abstract

Personal hygiene of food handlers at tofu production IRTPs in the Cotton Area is known to not use PPE, smoke in the workplace, and pack directly by hand. The purpose of this study was to describe personal hygiene and sanitation for the home industry of tofu production in the Kapas Region, Bojonegoro Regency. This type of research is descriptive, with a population of all home industries producing tofu in the Cotton Region as many as 5 IRTPs. The test parameters were Escherichia coli on the palm swab sample of the handler and MPN Coliform on the tofu soaked water source sample. Data were analyzed descriptively. The results showed that the personal hygiene of the handlers was in sufficient category (47.69%). Industrial sanitation conditions are categorized as sufficient (44%). The swab results of 5 samples of the handlers' palms were all negative for Escherichia coli and the tofu soaking water source did not exceed the maximum limit of the MPN Coliform parameter as many as 3 industries.Keywords: personal hygiene; household food industry sanitation; Escherichia coli; MPN ColiformABSTRAK Personal hygiene penjamah makanan di IRTP produksi tahu di Wilayah Kapas diketahui tidak menggunakan APD, merokok di tempat kerja, dan pengemasan langsung dengan tangan. Tujuan penelitian ini adalah menggambarkan personal hygiene dan sanitasi industri rumah tangga produksi tahu di Wilayah Kapas, Kabupaten Bojonegoro. Jenis penelitian ini adalah deskriptif, dengan populasi seluruh industri rumah tangga produksi tahu di Wilayah Kapas sejumlah 5 IRTP. Parameter uji berupa Escherichia coli pada sampel swab telapak tangan penjamah dan MPN Coliform pada sampel sumber air rendaman tahu. Data dianalisis secara deskriptif. Hasil penelitian menunjukkan bahwa personal hygiene penjamah berkategori cukup (47,69%). Kondisi sanitasi industri berkategori cukup (44%). Hasil swab 5 sampel telapak tangan penjamah seluruhnya adalah negatif Escherichia coli dan sumber air rendaman tahu dalam keadaan tidak melebihi batas maksimum parameter MPN Coliform sebanyak 3 industri.Kata kunci: personal hygiene; sanitasi industri rumah tangga pangan; Escherichia coli; MPN Coliform
Relaksasi Benson Dan Pengaruhnya Terhadap Nyeri Pasien Rawat Inap Penyakit Arteri Koroner (CAD) Ai Cahyati; Lia Herliana
Jurnal Penelitian Kesehatan SUARA FORIKES 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf.v0i0.1745

Abstract

Coronary heart disease is the most common heart function disorder which is characterized by a lack of oxygenated blood supply to the myocardium caused by coronary artery atherosclerosis, with the initial symptoms of severe pain in the chest area and does not subside when it lasts more than 20 minutes. One of the cognitive behavioral interventions that can be done is Benson relaxation. The purpose of this study was to analyze the effect of Benson's relaxation on pain perception in patients with coronary heart disease. The design of this research was pretest-posttest with control group. Samples were 30 patients with coronary heart disease who were treated at RSUD Dr. Soekardjo Tasikmalaya. In the pretest and posttest phases, pain levels were measured with a scale of 0 to 10. The results of the comparison test showed p value = 0.02, thus there was a difference in pain levels between before and after Benson relaxation. Furthermore, it was concluded that relaxation is effective for reducing pain in patients with coronary heart disease. Keywords: coronary heart disease; Benson's relaxation; pain scale ABSTRAK Penyakit jantung koroner adalah gangguan fungsi jantung yang paling sering ditemukan yang ditandai dengan kurangnya suplai darah beroksigen ke miokardium yang disebabkan oleh aterosklerosis arteri koroner, dengan gejala awal yaitu nyeri hebat di area dada dan tidak berkurang ketika melebihi 20 menit. Salah satu intervensi perilaku kognitif yang bisa dilakukan adalah relaksasi Benson. Tujuan dari penelitian ini adalah untuk menganalisis pengaruh relaksasi Benson terhadap persepsi nyeri pasien dengan penyakit jantung koroner. Rancangan penelitian ini adalah pretest-posttest with control group. Sampel adalah 30 pasien penyakit jantung koroner yang dirawat di RSUD Dr. Soekardjo Tasikmalaya. Pada fase pretest dan posttest dilakukan pengukuran tingkat nyeri dengan skala 0 sampai 10. Hasil uji komparasi menunjukkan nilai p = 0,02, dengan demikian ada perbedaan tingkat nyeri antara sebelum dan sesudah dilakukan relaksasi Benson. Selanjutnya disimpulkan bahwa relaksasi efektif untuk menurunkan nyeri pada pasien dengan penyakit jantung koroner.Kata kunci: penyakit jantung koroner; relaksasi Benson; skala nyeri
Support Tipe Keluarga Terhadap Kegagalan Cakupan ASI Eksklusif Sunarto Sunarto; Ayesha Hendriana Ngestiningrum; Wiwin Fajar Suryani
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf.v13i2.1974

Abstract

Research on exclusive breastfeeding coverage is often associated with direct variables such as; husband's support, information support, promotion, mother's knowledge, mother's job, socio-cultural, attitude and behavior of health workers. This study focuses on family type support as an indirect factor that affects the failure of exclusive breastfeeding in the working area of Sine Health Center, Ngawi. The purpose of this study was to determine the effect of nuclear family and extended family support on exclusive breastfeeding. This type of research is observational with a cross-sectional approach. The subjects of this study were 31 mothers who had babies aged one month. The method of data collection was using guided interviews, which contained 28 questions. The data analysis technique was the proportion and prevalensice ratio, while the proof of the hypothesis was done by using the Chi-Square test. The results showed that the most education was basic education, the most occupations were housewives, and the highest income was Rp. 1,500,000 to Rp. 2,500,000. Negative family support was more often received by breastfeeding mothers from extended family types. Negative family support had an effect on the failure of exclusive breastfeeding by 64.3%. Positive family support but the effect of exclusive breastfeeding failure was 23.5%. Negative family support was a risk factor for failure in exclusive breastfeeding with a prevalensice ratio of 2.73. The results of the Chi-Square test showed p = 0.022, meaning that there was a relationship between family support and exclusive breastfeeding in the first month of birth (0-1 month). It was concluded that negative family support regarding exclusive breastfeeding had an impact on the failure of the exclusive breastfeeding program. Negative family support is played predominantly by grandmother's decisions. The existence of breastfeeding mothers in the extended family type is at risk of experiencing failure in exclusive breastfeeding due to the grandmother's dominance factor. Information support and continuous health education are needed for grandmothers, husbands and other family members about the importance of exclusive breastfeeding for infants aged 0-6 months through various media.Keywords: family support; family type; exclusive breastfeeding ABSTRAK Penelitian tentang cakupan ASI eksklusif sering dikaitkan dengan variabel langsung seperti; dukungan suami, dukungan informasi, promosi, pengetahuan ibu, pekerjaan ibu, sosial budaya, sikap dan perilaku petugas kesehatan. Penelitian ini berfokus pada support tipe keluarga sebagai faktor tidak langsung yang mempengaruhi kegagalan ASI eksklusif di wilayah kerja Puskesmas Sine, Ngawi. Tujuan penelitian ini adalah untuk mengetahui pengaruh support keluarga tipe nuclear family dan extended family terhadap pemberian ASI eksklusif. Jenis penelitian ini adalah observasional dengan pendekatan cross-sectional. Subyek penelitian ini adalah 31 ibu yang memiliki bayi usia satu bulan. Metode pengumpulan data adalah menggunakan wawancara terbimbing, yang berisi 28 pertanyaan. Teknik analisis data adalah proporsi dan rasio prevalensisi, sedangkan pembuktian hipotesis dilakukan dengan menggunakan uji Chi-Square. Hasil penelitian menujukkan bahwa pendikan terbanyak adalah pendidikan dasar, pekerjaan terbanyak adalah ibu rumah tangga, penghasilan terbanyak adalah Rp 1.500.000 sampai Rp 2.500.000. Support keluarga negatif lebih sering diterima oleh ibu menyusui dari tipe keluarga extended family. Support keluarga negatif memberikan pengaruh terhadap kegagalan pemberian ASI eksklusif sebesar 64,3%. Support keluarga positif tetapi memberikan efek kegagalan ASI eksklusif sebesar 23,5%. Support keluarga negatif merupakan faktor resiko penyebab kegagalan dalam pemberian ASI eksklusif dengan besar rasio prevalensisi = 2,73. Hasil uji Chi-Square menunjukkan p = 0,022, artinya terdapat hubungan antara support keluarga dengan pemberian ASI eksklusif pada bulan pertama kelahiran (0-1 bulan). Disimpulkan bahwa support keluarga negatif tentang ASI eksklusif berdampak pada kegagalan program pemberian ASI eksklusif. Support keluarga negatif diperankan secara dominan oleh keputusan nenek. Keberadaan ibu menyusui di tipe keluarga extended family beresiko mengalami kegagalan dalam pemberian ASI secara eksklusif dari faktor dominasi nenek. Diperlukan dukungan informasi dan pemberian pendidikan kesehatan terus menerus kepada nenek, suami dan anggota keluarga lainnya tentang pentingnya ASI eksklusif pada bayi usia 0-6 bulan melalui berbagai media.Kata kunci: support keluarga; tipe keluarga; ASI eksklusif
Hubungan antara Pengetahuan, Sikap, Perilaku Terkait Anemia dan Asupan Zat Besi dengan Kejadian Anemia pada Mahasiswi Baru STIKes Mitra Keluarga Mayang Dwi Saputri; Noerfitri Noerfitri
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf13216

Abstract

Anemia is a health problem worldwide, especially in developing countries. This study aims to analyze the relationship between knowledge, attitudes, behavior related to anemia and iron intake with the incidence of anemia in new students of STIKes Mitra Keluarga. The design of this study was cross-sectional. The research subjects were 120 new students of STIKes Mitra Keluarga selected by consecutive sampling technique. Data on knowledge, attitudes, and behaviors related to anemia were obtained through a questionnaire. Data on iron intake were obtained through recall-24H, and data on anemia status were obtained through Medical Check-up (MCU) results for new students. The p values for each independent variable were 0.001, 0.920, 0.204 and 0.001 respectively. Furthermore, it was concluded that the factors related to the incidence of anemia were knowledge and iron intake.Keywords: anemia; knowledge; iron intake ABSTRAK Anemia merupakan salah satu masalah kesehatan di seluruh dunia terutama di negara sedang berkembang. Penelitian ini bertujuan untuk menganalisis hubungan antara pengetahuan, sikap, perilaku terkait anemia dan asupan zat besi dengan kejadian anemia pada mahasiswi baru STIKes Mitra Keluarga. Desain penelitian ini adalah cross-sectional. Subjek penelitian adalah 120 mahasiswi baru STIKes Mitra Keluarga yang dipilih dengan teknik consecutive sampling. Data mengenai pengetahuan, sikap, dan perilaku terkait anemia diperoleh melalui kuesioner. Data mengenai asupan zat besi diperoleh melalui recall-24H, dan data mengenai status anemia diperoleh melalui hasil Medical Check-up (MCU) mahasiswi baru. Nilai p untuk masing-masing variabel bebas secara berurutan adalah 0,001, 0,920, 0,204 dan 0,001. Selanjutnya disimpulkan bahwa faktor yang berhubungan dengan kejadian anemia adalah pengetahuan dan asupan zat besi.Kata kunci: anemia; pengetahuan; asupan zat besi
Efektifitas Konseling Antenatal Terpadu Terhadap Pengetahuan Ibu Hamil di Puskesmas Pabuaran Tumpeng, Tangerang Yenny Aulya; Ira Kuswandari; Anni Suciawati; Febry Mutiariami
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf.v13i2.1889

Abstract

Pregnancy is a normal reproductive process that requires special self-care so that the mother and fetus are in good health. This study aims to determine the effectiveness of integrated antenatal counseling on knowledge about pregnant women's visits at the Pabuaran Tumpeng Public Health Center. The design of this research was one group pretest-posttest. The subjects were 40 pregnant women who were selected by accidental sampling technique. Data about knowledge were collected through filling out questionnaires, then data analysis was carried out using the Wilcoxon test. The results showed that the mother's knowledge in the pretest phase was mostly in the sufficient category (62.5%); while in the posttest phase it increased to good category (75%). The results of the statistical test showed the value of p = 0.000 (there was a significant difference). Furthermore, it was concluded that integrated antenatal counseling was effective in increasing mother's knowledge about pregnant women's visits.Keywords: integrated antenatal care; counseling; knowledge; visit ABSTRAK Kehamilan merupakan proses reproduksi yang normal yang memerlukan perawatan diri secara khusus agar ibu dan janin dalam keadaan sehat. Penelitian ini bertujuan untuk mengetahui efektivitas konseling antenatal terpadu terhadap pengetahuan tentang kunjungan ibu hamil di Puskesmas Pabuaran Tumpeng. Rancangan penelitian ini adalah one group pretest-posttest. Subyek adalah 40 ibu hamil yang dipilih dengan teknik accidental sampling. Data tentang pengetahuan dikumpulkan melalui pengisian kuesioner, lalu dilakukan analisis data menggunakan uji Wilcoxon. Hasil penelitian menunjukkan bahwa pengetahuan ibu pada fase pretest sebagian besar berada dalam kategori cukup (62,5%); sedangkan pada fase posttest mengalami peningkatan menjadi kategori baik (75%). Hasil uji statistik menunjukkan nilai p = 0,000 (ada perbedaan secara signifikan). Selanjutnya disimpulkan bahwa konseling antenatal terpadu efektif untuk meningkatkan pengetahuan ibu tentang kunjungan ibu hamil.Kata kunci: antenatal terpadu; konseling; pengetahuan; kunjungan 
Determinan Kejadian Hipertensi dalam Kehamilan Suparji Suparji; Heru Santoso Wahito Nugroho; Karwati Karwati; Yessy Dessy Arna
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf13212

Abstract

Hypertension in pregnancy is a blood vessel disorder that occurs during pregnancy or occurs during pregnancy or the puerperium. Hypertension in pregnancy is still one of the causes of maternal death. The purpose of this study was to determine the effect of a history of hypertension, obesity, use of hormonal contraception on the incidence of hypertension in pregnancy. This type of research was analytic observational, with a cross-sectional design. The population of this study was 332 pregnant women who visited and registered in Maospati Heath Center, Magetan Regency. The sample size in this study was 182 pregnant women who were selected by simple random sampling technique. Data were collected through filling out questionnaires and verbal autopsy documents, maternity medical records, and registers for the cohort of pregnant women. The data were analyzed descriptively, followed by the Chi square test, and ended with the logistic regression test. The results of the analysis showed that the p-values for each factor were: history of hypertension = 0.01, history of obesity = 0.024, history of hormonal family planning = 0.21. Furthermore, it was concluded that a history of hypertension and a history of obesity were the determinants of hypertension in pregnancy in Maospati, Magetan.Keywords: hypertension in pregnancy; history of hypertension; history of obesity ABSTRAK Hipertensi dalam kehamilan adalah gangguan pembuluh darah yang terjadi pada kehamilan atau timbul pada masa kehamilan atau nifas. Hipertensi dalam kehamilan masih menjadi salah satu penyebab kematian ibu. Tujuan penelitian ini adalah untuk mengetahui pengaruh riwayat hipertensi, obesitas, penggunaan kontrasepsi hormonal terhadap kejadian hipertensi pada kehamilan. Jenis penelitian ini adalah observasional analitik, dengan desain cross-sectional. Populasi penelitian ini adalah 332 ibu hamil yang berkunjung dan tercatat di Puskesmas Maospati, Kabupaten Magetan. Besar sampel dalam penelitian ini adalah 182 ibu hamil yang dipilih dengan teknik simple random sampling. Data dikumpulkanmelalui pengisian kuesioner dan dokumen otopsi verbal, rekam medis bersalin, dan register kohort ibu hamil. Data dianalisis secara deskriptif, dilanjutkan dengan uji Chi square, dan diakhiri dengan uji regresi logistik. Hasil analisis menunjukkan bahwa nilai p untuk masing-masing faktor adalah: riwayat hipertensi = 0,01, riwayat obesitas = 0,024, riwayat KB hormonal = 0,21. Selanjutnya disimpulkan bahwa riwayat hipertensi dan riwayat obesitas adalah determinan dari hipertensi daloam kehamilan di Maospati, Magetan.Kata kunci: hipertensi dalam ehamilan; riwayat hipertensi; riwayat obesitas
Pengaruh Variasi Konsentrasi Ekstrak Daun Kelor (Moringa oleifera Lamk) Terhadap Efek Antiinflamasi Sediaan Emulgel Octavianus Robby; Fransisca Gloria; Tunik Saptawati
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 13, No 2 (2022): April 2022
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf.v13i2.1820

Abstract

Moringa is a plant that is often used as a treatment and contains phytochemical compounds, one of which is a flavonoid that can be used as an anti-inflammatory. The purpose of this study was to formulate the ethanolic extract of Moringa leaves in the form of an emulgel with various extract concentrations of 5%, 7.5%, 10%. Emulgel formula consists of ethanol extract of Moringa leaves, carbopol 940, TEA, tween 80, methyl paraben, propyl paraben, propylene glycol and aquadest. Examination of the physical characteristics of the emulgel included: organoleptic, homogeneity, pH, spreadability, adhesion. The emulgel preparation was tested for its anti-inflammatory effect on male white rats of the wistar strain induced by carrageenan. The data obtained were analyzed statistically, namely the Anova test. The results of the examination of the characteristics of the emulgel which included organoleptic, homogeneity, pH, dispersion, and adhesion met the requirements for topical preparations. In the anti-inflammatory effect test of formula III, the highest percentage of inflammation reduction was 14.40% compared to the negative control, formula I and formula II. The Aova test results showed a p value <0.05. It was concluded that there were significant differences in the effect of variations in the concentration of Moringa leaf extract.Keywords: emulgel; Moringa leaf extract; anti-inflammatory ABSTRAK Kelor merupakan tanaman yang sering dimanfaatkan sebagai pengobatan dan mengandung senyawa fitokimia yang salah satunya adalah flavonoid yang dapat digunakan sebagai antiinflamasi. Tujuan penelitian ini adalah memformulasikan ekstrak etanol daun kelor dalam bentuk sediaan emulgel dengan variasi konsentrasi ekstrak 5%, 7,5%, 10%. Formula emulgel terdiri dari ekstrak etanol daun kelor, carbopol 940, TEA, tween 80, metil paraben, propil paraben, propilenglikol dan aquadest. Pemeriksaan karakteristik fisik emulgel meliputi: organoleptis, homogenitas, pH, daya sebar, daya lekat. Sediaan emulgel diuji efek antiinflamasi pada tikus putih jantan galur wistar yang diinduksi karagenan. Data yang diperoleh dianalisis secara statistik yaitu uji Anova. Hasil pemeriksaan karakteristik emulgel yang meliputi organoleptis, homogenitas, pH, daya sebar, daya lekat memenuhi syarat sediaan topikal. Pada uji efek antiinflamasi formula III, nilai persen penurunan radang yang paling tinggi yaitu 14,40% dibandingkan kontrol negatif, formula I dan formula II. Hasil uji Aova menunjukkan nilai p <0,05. Disimpulkan bahwa terdapat perbedaan efek secara signifikan dari variasi konsentrasi ekstrak daun kelor.Kata kunci: emulgel; ekstrak daun kelor; antiinflamasi

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