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Journal of Medicine and Health

jmh
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Published by Universitas Kristen Maranatha

ISSN : 24425227 EISSN : - DOI : -

Core Subject : Health, Science,

Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Journal of Medicine and Health (JMH) is an open access journal (OAJ), a periodic scientific publication biannually online published on February and August; using review and screening system by peer group reviewer. JMH receives original research articles which related to medicine, health, new developing therapy from traditional medicine or herbs and developing clinical therapy. JMH also receives otiginal review articles, case report, continuing medicine and health study. Articles should be written in good English or Indonesian language.

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Articles 264 Documents

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A Case Report: Clozapine in Diabetic Patient with Bipolar Mood Disorder _ Vera; Christine Sitha
Journal of Medicine and Health Vol. 1 No. 1 (2015)
Publisher : Universitas Kristen Maranatha

Depression and diabetes are often occur together and their morbidity has a significant impact of health outcomes. Antidepressants dan antipsychotics may cause metabolic abnormalities, as well as neurologic abnormalities. 52 years old diabetic woman presented to Immanuel Teaching Hospital with slurred speech. Since ten years ago, she had bipolarÂ moodÂ disorder, which was recently treated with clozapine. As patient consumed higher dose of clozapine (beyond her psychiatristâ€™s supervision), she had uncontrolled blood glucose level, fever, and slurred speech. The side effects of clozapine (weight gain, increased insulin resistance, dysarthria, fever) were discussed in this case report. During hospitalization, with strict supervision of clozapine use, the symptoms resolved. In diabetic patients with comorbid psychiatric disorders, a good collaboration between internist and psychiatrist is required to manage the patients effectively and comprehensively.Â Keywords: bipolar mood disorder, clozapine, diabetes mellitus, depression

POTENCY OF VINEGAR THERAPY IN OTOMYCOSIS PATIENTS Eman Sulaiman; Bambang Purwanto; Lina Lasminingrum; Yussy Afriani Dewi; Sally Mahdiani
Journal of Medicine and Health Vol. 1 No. 2 (2015)
Publisher : Universitas Kristen Maranatha

Otomycosis is an outer ear canal infection caused by fungi. Clinicians are trying to find out the most effective antifungal drug for treating otomycosis. Traditionally Apple cider vinegar has been used for the treatment of various diseases, including antifungal.The high cost in otomycosis treatment effort, long duration of treatment, high recurrence rate, and the difficulty in the application of drugs in the otomycosis treatment have encouraged the researcher to do this study. Having evaluated Â the improvement of clinical symptoms, otoscopy view and examination of KOH 10% in patients receiving apple cider vinegar therap, this study uses descriptive study design of four otomycosis patients in the ORL HNS outpatient clinic of Hasan Sadikin Hospital Bandung from July to August 2014. Having evaluated a clinical symptoms improvement, it is found out that there is an increase of otoscopy view and examination of KOH 10% in patients receiving apple cider vinegar. In other words, there is an Improvement of clinical symptoms, otoscopy view, and examination of KOH 10% in patients receiving apple cider vinegar therapy. Topical apple cider vinegar therapy gives a good result in the improvement of clinical symptom,otoscopy view, and examination of KOH 10% in otomycosis Â patients.Â Keywords: otomikosis, sign and symptoms improvement, apple cider vinegar.

Peer Reviewers of JMH Volume 1 Number 2 Journal of Medicine and Health
Journal of Medicine and Health Vol. 1 No. 2 (2015)
Publisher : Universitas Kristen Maranatha

We would like to thank our peer reviewers for the precious contributions in providing clinical,scientific, and methodological expertise for JMH Volume 1 Number 2. We appreciate everythoughtful review of submitted manuscripts and for making important contributions to improve thescientific quality of articles published in JMH. We listed the names in alphabetical order.Dr. dr Diana Krisanti Jasaputra, M.Kesdr. Djaja Rusmana, M.Si.Dra Endang Evacuasiany, M.S, AFKdr. Fenny, Sp.PKDr. dr. Hana Ratnawati, M.Kes., PA(K)Prof. Dr. Ida Parwati, dr, SpPK(K), PhDdr. Indra Sapta, Sp.THT-KLIngrid S. Surono, PhD.Dr. dr. Meilinah Hidayat, M.Kesdrg. Monica Irewaty Wibisana, M.Kes Sert Ortdr Sijani Prahastuti,M.Kesdrg.Susiana,Sp.OrtProf. Drs. Sutiman B.Sumitro,SU.,D.ScSylvia Soeng, dr., M.Kes., PA(K)Dr. Teresa Liliana W, S.Si., M.Kes., PA(K)Prof. dr. Wahyuni Lukita Atmadja, PhD.Dr. Yudi Mulyana H.,dr.,SpOG(K)

The Ethanol Extract of Neem Leaf (Azadirachta Indica A. Juss) Effect towards Wound Healing in Male Swiss Webster Mice Hillary L. Mustamu; Endang Evacuasiany; Laella K. Liana
Journal of Medicine and Health Vol. 1 No. 3 (2016)
Publisher : Universitas Kristen Maranatha

accelerates wound healing. We examined the effect of Ethanol Extract of Neem Leaf (EENL) inaccelerating wound healing and compared its potential with povidone iodine. This was ananalytic experimental study, using Complete Randomized Design (CRD) with a comparativemethod. We used 30 male Swiss Webster mice that were divided into five groups (n=6). Eachgroup was given the Ethanol Extract of Neem Leaf (EENL) with a concentration of 25%, 12.5%and 25%, aquades (negative control) and povidone iodine 10% (comparison). The averagewound healing time of EENL 25%, EENL 12.5% , EENL 6.25% , povidone iodine and aquadeswere 11.2; 12.2;13.2;13.2;and 1.3 days respectively. The data was analized with one wayANOVA and showed a highly significant difference of p=0.000. Tukey HSD test showed thatEENL 25% and 12.5% had better potential than povidone iodine 10% and EENL 6.25% had thesame potential with povidone iodine 10%. This study concludes that ethanol extract of neem leafhas an effect in accelerating the duration of wound healing, with EENL 25% as the bestconcentration in accelerating the duration of wound healing.Keywords: neem leaf, Azadirachta indica A. Juss, wound healing, Swiss Webster mice

The Preventive Effect of Fig Leavesâ€™s (Ficus carica L.) towards Colon Histopathological Feature and IL-6 Serum Level on Ulcerative Colitis Induced Mice Hartini Tiono
Journal of Medicine and Health Vol. 1 No. 4 (2016)
Publisher : Universitas Kristen Maranatha

Ulcerative colitis is a chronic inflammatory disease mainly affects sigmoid colon and rectum. The inflammation process will activate NF-ÎºB and leads to proinflamatory cytokine release such as Interleukin-6 (IL-6). Fig leaves contain a high level of flavonoid which can prevent NF-ÎºB activation, and further inhibits IL-6 secretion. This research aims to see the preventive effect of methanolic extract of fig leaves towards colon histopathological feature and IL-6 serum level on ulcerative colitis induced mice. Balb/C male mice were randomly assigned into 5 groups (n=5). The treatment groups were dextran suphate sodium (DSS) control group (group I), methanolic extract of Fig leaves dose 28 mg/ day control group (group II), and methanolic extract of Fig leaves dose 7 mg/ day (group III), 14 mg/ day (group IV), and 28 mg/ day (group V) for 14 days, which at the 8th till 14th day were given DSS to induce colitis. The results showed that both of colon mucosal damage and IL-6 serum level of group I were significantly different from other groups (p=0,029). InÂ conclusion, the methanolic extract of Fig leaves can improve colon mucous damage and decrease IL-6 serum level on ulcerative colitis-induced mice.Â Keywords: ulcerative colitis, fig leaves, colon mucousal damage, interleukin-6

The Effect of Chicken (Gallus gallus domesticus) Eggshellâ€™s Powder towards Wound Healing of Incision Wound on Male Swiss-Webster Mice Rahman A. Nugraha; Harijadi Pramono; Roro Wahyudianingsih
Journal of Medicine and Health Vol. 1 No. 4 (2016)
Publisher : Universitas Kristen Maranatha

Domestic chicken eggshells contain calcium and protein that could be useful in wound healing process. This research was conducted to determine whether domestic chicken eggshells can accelerate wound healing. Twenty one male Swiss-Webster miceÂ with 2 cm incision were divided into 3 groups. Negative control group were given Carboxymethyl cellulose 1% (CMC), positive control group were given feracrylum 1% (FER), and the eggshells group given domestic chicken eggshells powder (KT). Treatment and data mesurement was measured every day untilÂ the 7th day. On the 7thÂ day the average length of the wound were analyzed and the skin tissue is taken for microscopic examination. Data analyzed using one-way ANOVA followed by Post Hoc Least Significant Difference (LSD) with p=0,05. On macroscopic examination, there wereÂ highly significant differences between KT compared to CMC and highly significant differences between KT compared to FER. the average length of wound on the 7th day on KT 0,63 cm shorter than CMC 1,07 (p=0,000) and FER 0,81 cm (p=0,003). On microscopic examination, the degree of reepithelization on KT groups are severe, moderate for collagen density, fibroblasts density, subepithelial neutrophil density, degree of edema, and mild for angiogenesis. We conclude domestic chicken eggshells powder can accelerate wound healing.Â Key words: domestic chicken eggshells, incision wound, wound healing

Topical Effect of Pinneaple (Ananas comosus) Juice in Combustio Healing Process Measured by Granulation Process, Reepitelialisation and Angiogenesis Cherry Azaria; Achadiyani Achadiyani; Reni Farenia
Journal of Medicine and Health Vol. 1 No. 5 (2017)
Publisher : Universitas Kristen Maranatha

Skin protects the body from various trauma, such as high temperature trauma known ascombustio. Pineapple (Ananas comosus) contains lots of substances such as bromelain,antioxidants, and zinc shown to accelerated healing process in previous experiments. Aim ofthis research was to analize the effect of topical pinneaple juice application in combustiohealing process. The method was true experimental laboratory. Wistar ratsâ€™ back skin wereinduced by 100 o C iron plat untill 2 nd degree combustio occured, then divided into two groups(n=20). The treatment group were given topical application of pinneaple juice, then the healingprocess were observed macroscopically and microscopically on day 0, 3, 7, and 14. The resultshowed better wound healing in treatment group on day 14. MANOVA test showed topicalapplication of pinneaple juice accelerated healing process (p=0.001). Treatment group showedbetter histological structure changes, as seen from better granulation tissue formed (p=0.003)and reepithelization (p=0,000), but not from angiogenesis (p=0.733). Conclusion, topicalapplication of pinneaple (Ananas comosus) juice accelerated healing process in 2 nd grade ofcombustio animal model measured by granulation maturation process and reepithelizationprocess, but has no effect on angiogenesis.Keywords : Ananas comosus juice, 2 nd degree combustio, granulation tissue, reepitelisation,angiogenesis.

Snake-Bite with Disseminated Intravascular Coagulation (DIC) and Stage II Hypertension Hendra Subroto; Leni Lismayanti
Journal of Medicine and Health Vol. 1 No. 5 (2017)
Publisher : Universitas Kristen Maranatha

Snake-bite is an important medical emergency case and caused of many hospitaladmission especially in the rural area, forests, plantations and swamps. Despite its importance,there have been fewer proper data of snake-bite incidence in Indonesia. World HealthOrganization estimate that at least 421,000 envenomings and 20,000 deaths from snakebitesoccur each year, especially in South and South East Asia and sub-Saharan Africa. The authorsreport a case of a 76-year-old man came to Hasan Sadikin Hospital with chief complaint woundin his right hand and right forearm from snake-bite. Snake-bites can cause DIC because thevenom activates the coagulation system and cause fibrinolysis which occurs in less than 24hours. Laboratory results, we found abnormalities such as anemia, thrombocytopenia,hypofibrinogenemia, and increased levels of D-dimer. Patients were treated for 8 days and thenallowed to go home. Snake-bite is an occupational disease of farmers, plantation workers,herdsmen, fishermen, other. Snake bite cases require prompt and comprehensive managementso as to minimize the possibility of disability and death.Keywords: snake bite, DIC, hypertension

Correlation between Prostate-Specific-Antigen (PSA) Level and Prostate Volume in Benign Prostatic Hyperplasia at Bhayangkara Hospital Mataram Daniel M Krisna; Akhada Maulana; Erwin Kresnoadi
Journal of Medicine and Health Vol. 1 No. 6 (2017)
Publisher : Universitas Kristen Maranatha

Prostate enlargement is the most quality of life-impacted problem in elderly. Proper diagnoses and prostate volume prediction are important in considering the best treatment. PSA is a glycoprotein specifically secreted by prostate glands and influenced by various condition, such as Benign Prostatic Hyperplasia (BPH). The aim of this study is to identify the correlation between PSA serum level and prostate mass volume. This was a descriptive study with cross-sectional design that conducted at Bhayangkara Hospital Mataram on April 2015. Data were analyzed using Pearson correlation test and multiple regression logistic, to determine the relationship between PSA serum levels and prostate mass volume. The average PSA level was 34,62 ng/mL (1,82-30,70 ng/mL), and the average prostate mass volume were 72,57cc. There was correlation between PSA serum levels with prostate mass volume ( r = 0,384, p = 0,815). Conclusion, there is a relationship between PSA levels with prostate volume in BPH patients in Bhayangkara Mataram hospital.Keywords: Bhayangkara Hospital Mataram, BPH, prostate volume, PSA

The Risk of Falling in Elderly Increased with Age Growth and Unaffected by Gender Susilo, Wilson; Limyati, Yenni; Gunawan, Decky
Journal of Medicine and Health Vol. 1 No. 6 (2017)
Publisher : Universitas Kristen Maranatha

Elderly people are a group of people with age of 60 and above. Studies in United States showed one-third of elderly people experienced fall in their houses and one-forty of them need bedrest in hospital. Falling can cause physical and mental injury. Physical injury manifests as fracture, hematoma, bruises, and dislocation, and mental injury manifests as lack of self esteem. This study aimed to examine the relation between age and gender on risk of fall on elderly people. This is a cross-sectional analytical study involving 23 elderly people from Tulus Kasih Elderly Home that met the inclusion criteria. Risk of fall were checked with Timed Up and Go Test. The data acquired were analyzed with chi-square with Î± = 0,05. As results, age significantly affected risk of fall (p=0.019) but gender did not (p=0.265). We concluded the risk of falling is increased with age and unaffected by gender.Keywords : age, gender, risk of fall, timed up and go test

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