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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Published by Universitas Gadjah Mada
ISSN : 20888139     EISSN : 24432946     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.
Arjuna Subject : -
Articles 487 Documents
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EFFECT OF GIVING ANTIHYPERTENSIVE DRUG AGAINST REDUCTION OF BLOOD PRESSURE IN ACUTE ISCHEMIC STROKE PATIENTS WHO HOSPITALIZED IN RSUP DR. SARDJITO YOGYAKARTA Wahyu Sedjatiningsih; Zullies Ikawati; Abdul Gofir
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.85

Abstract

Incidence of ischemic stroke 10 times more often than haemorrhagic stroke in the the west countries, but haemorrhagic stroke has a higher risk of mortality than ischemic stroke. One focus of acute stroke management is the management of hypertension. Blood pressure reduction in ischemic stroke patients could potentially reduce the risk of brain edema, the risk of hemorrhage, and prevent further vascular damage. However, an aggressive blood pressure reduction can cause a decrease in perfusion pressure to the ischemic area. Most hypertensive patients require two or more antihypertensive medications to achieve blood pressure targets. This study used observational study design with retrospective data collection on medical records of acute ischemic stroke patients and performed in RSUP Dr. Sardjito Yogyakarta period January 2010-December 2010. Data were analyzed with descriptive analysis and chi-square evaluative analysis on the relationship between the type of therapy with a reduction in blood pressure of acute ischemic stroke patients. Initial antihypertensive medication use in patients with acute ischemic stroke in RSUP Dr. Sardjito were 13 types of five classes of antihypertensive drugs. After getting a single antihypertensive medication, patients who experienced a decrease in systolic blood pressure on day-3 was 60%, while 17% fixed and 23% up and after getting a combination of antihypertensive medications, patients who experienced a decrease in systolic blood pressure on day-3 was 75%, while 10% fixed and 15% rise. Antihypertensive drug therapy alone or in combination had the same ability to lower systolic blood pressure (p = 0.260) and diastolic (p = 0.567) in patients with acute ischemic stroke in RSUP Dr. Sardjito Yogyakarta. Keywords: Hypertension, acute ischemic stroke, single antihypertensive drug, antihypertensive drug combinations, RSUP Dr.Sardjito Yogyakarta
PENGGUNAAN ANTIBIOTIK TERHADAP LUARAN KLINIK PASIEN INFEKSI SALURAN KEMIH AKIBAT KATETERISASI Denia Yuni Wulandari; Djoko Wahyono; Rizka Humardewayanti Asdie
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 6, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.259

Abstract

Infeksi saluran kemih akibat kateterisasi didefinisikan sebagai infeksi pada pasien yang pernah atau masih menggunakan kateter indwelling (menetap). Penggunaan antibiotik secara tidak rasional dapat menimbulkan pengobatan kurang efektif, resiko efek samping, meningkatnya resistensi antibiotik dan tingginya biaya pengobatan. Penelitian ini bertujuan untuk mengetahui rasionalitas penggunaan antibiotik dan pengaruhnya terhadap luaran klinik pasien infeksi saluran kemih akibat kateterisasi.Penelitian ini merupakan penelitian analitik dengan menggunakan desain cohort retrospektif dengan pengambilan data secara retrospektif berdasarkan data catatan medis pasien infeksi saluran kemih akibat kateterisasi di RSUP Dr. Sardjito Yogyakarta periode Januari 2013-November 2015. Pasien yang memenuhi kriteria inklusi dievaluasi rasionalitas penggunaan antibiotiknya dengan metode Gyssens serta outcome klinik setelah terapi antibiotik empiris diberikan selama tiga hari. Data dianalisis dengan uji statistik Chi-square (variabel kategorik).Jumlah pasien pada penelitian ini sebanyak 63 pasien. Hasil penelitian menunjukkan bahwa penggunaan antobiotik empiris yang diberikan pada pasien CAUTI setelah dievaluasi dengan metode Gyssens, dari 63 pasien diketahui 49 (77,77 %) pasien penggunaannya rasional (kategori 0) dan 14 pasien (22,22 %) tidak rasional. Penggunaan antibiotik rasional pada pasien infeksi saluran kemih akibat kateterisasi memberikan luaran klinik lebih baik dibandingkan dengan pasien yang mendapatkan antibiotik tidak rasional.Kata kunci: Infeksi saluran kemih akibat kateterisasi, antibiotik, rasionalitas, luaran klinik, metode Gyssens
PERAN INTERPROFESSIONAL EDUCATION TERHADAP PERSEPSI KETERLIBATAN APOTEKER DALAM KOLABORASI ANTAR PROFESI Dzikrina Ilmanita; M. Rifqi Rokhman
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 4, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.283

Abstract

Kolaborasi antar profesi mengharuskan semua profesi memiliki persepsi yang sama terhadap ranah masing-masing profesi termasuk ranahketerlibatan apoteker. Interprofessional education (IPE) dapat digunakan untuk menyamakan persepsi tersebut. Penelitian dilakukan untuk melihat peran IPE dalam mempengaruhi persepsi mahasiswa kesehatan terhadap keterlibatan apoteker pada kolaborasi antar profesi. Penelitian dilakukan pada Februari sampai Mei 2014 menggunakan rancangan cross sectional dengan alat ukur kuesioner pada satu univeritas yang sudah menerapkan IPE dan 1 universitas lainnya yang belum menerpkan IPE. Kuesioner mengukur tiga bentuk keterlibatan apoteker dalam kolaborasi antar profesi yaitu keterlibatan apoteker dalam IPE, kewenangan apoteker, dan tanggung jawab apoteker. Pengambilan sampel dengan metode kuota sampling ditetapkan 225 responden mahasiswa kesehatan yang terbagi menjadi kelompok yang sudah dan belum mendapatkan IPE. Data dianalisis menggunakan two way anova, one way anova,dan uji Tukey. Hasil penelitian menunjukkan mahasiswa yang sudah mendapat IPE secara signifikan mempunyai tingkat kesetujuan yang lebih tinggi pada 84,6% pertanyaan tentang keterlibatan apoteker dalam kolaborasi antar profesi, 33,3% pertanyaantentang tanggung jawab apoteker, dan 33,3% pertanyaan tentang kewenangan apoteker. Mahasiswa kedokteran, kedokteran gigi maupun farmasi yang sudah mendapatkan IPE memiliki tingkat percaya diri yang homogen. Tingkat percaya diri mahasiswa farmasi yang sudah mendapat IPE lebih tinggi daripada mahasiswa farmasi yang belum mendapat IPE. Kata kunci: kolaborasi antar profesi, interprofessional education, apoteker, mahasiswa kesehatan
HUBUNGAN KUALITAS PELAYANAN RAWAT JALAN PADA ERA JAMINAN KESEHATAN NASIONAL TERHADAP KEPUASAN PASIEN Heru Nurcahyo; Marchaban Marchaban; Sumarni Sumarni
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 5, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.135

Abstract

Peningkatan jumlah pasien di era Jaminan Kesehatan Nasional di puskesmas harus diikuti peningkatan pelayanan yang maksimal serta ditunjang dengan pengukuran kepuasan pasien terhadap pelayanan yang diberikan agar didapatkan masukan untuk program berkelanjutan. Tujuan penelitian untuk mengetahui variabel bebas Tangibles (bukti fisik), Reliability (reliabilitas), Responsiveness (daya tanggap), Assurance (jaminan), dan Empathy (empati), manakah yang masing-masing paling dominan berpengaruh terhadap kepuasan pasien dan untuk mengetahui apakah variabel bebas secara simultan berpengaruh terhadap kepuasan pasien. Populasi adalah pasien rawat jalan ke Puskesmas Margadana bulan Januari sampai Februari 2015. Pengambilan sampel akan dilakukan dengan menggunakan metode non-probability sampling dengan teknik purposive sampling. Metode pengumpulan data menggunakan kuesioner, jumlah koresponden 100 pasien, instrumen yang digunakan dalam penelitian ini adalah SERQUAL dengan uji analis regesi linear. Hasil berdasarkan nilai uji t yang paling berpengaruh terhadap variabel kepuasan konsumen adalah variabel Tangibles (bukti fisik), dan Assurance (jaminan). dengan nilai uji t signifikansi variabel bukti langsung sebesar 0,01<0,05 dan variabel jaminan 0,00<0,05. Berdasarkan nilai F hitung sebesar 22,99 dengan angka signifikansi (P value) sebesar 0,00. Dengan tingkat signifikansi 95% (α =0,05). Angka signifikansi (P value) sebesar 0,00<0,05 berarti variabel bebas mempunyai pengaruh signifikan secara simultan terhadap kepuasan pasien. Puskesmas Margadana Kota Tegal telah memperikan pelayanan baik dan variabel yang paling berpengaruh terhadap kepuasan konsumen adalah Tangibles (bukti fisik), dan Assurance (jaminan).
EVALUASI DISTRIBUSI DAN PENGGUNAAN OBAT PASIEN RAWAT JALAN DI RUMAH SAKIT ORTOPEDI Heru Sasongko; Satibi Satibi; Achmad Fudholi
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 4, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.273

Abstract

Manajemen obat yang baik merupakan salah satu aspek yang berpengaruh pada pelayanan kefarmasian. Tahap distribusi merupakan tahapan dari siklus manajemen obat yang sangat penting dan kompleks, sedangkan penggunaan obat merupakan tahap yang penting dan menjadi orientasi utama dalam pelayanan kefarmasian. Tujuan dalam penelitian ini adalah mengevaluasi pengelolaan obat tahap distribusi dan penggunaan pada pasien rawat jalan. Rancangan penelitian deskriptif observasional, data diambil secara retrospektif dan concurrent. Data berupa kualitatif dan kuantitatif disertai wawancara dengan pihak terkait. Pengambilan data selama bulan Februari – Maret 2014. Seluruh tahap pengelolaan obat diukur efisiensinya dengan menggunakan indikator WHO, Pudjaningsih, dan Depkes RI kemudian dibandingkan dengan nilai terbaik hasil penelitian terpilih. Hasil evaluasi tahap distribusi adalah kecocokan jumlah obat dengan kartu stok 99,33%, sistem penyimpanan obat secara First In First Out dan First Expired First Out, persentase stok mati 3,33%, kecepatan pelayanan resep yaitu 7 menit untuk sediaan jadi, untuk sediaan racik kurang dari 20 menit, jumlah obat yang diserahkan 100%, keterjaringan resep 100%, tidak adanya kesalahan pemberian obat 100%. Tahap penggunaan menunjukan hasil jumlah item obat perlembar resep 2,2 item, peresepan antibiotik 10,57%, peresepan obat generik 70,18%, peresepan injeksi 1,48%, kesesuaian dengan formularium 95,76%, obat yang dilabeli benar 100%, pasien faham cara penggunaan 100%. Kesimpulannya belum semua indikator dalam tahap distribusi dan penggunaan efisien. Kata kunci: distribusi, penggunaan, rawat jalan
Correspondence Analysis between Me Too Drugs Formulation with Patent Information and the Analytical Method (Case Study: Amlodipine Tablets - PT Indofarma (PERSERO) Tbk.) Fetrikani Andartaji; Gede Bayu Suparta; Marchaban Marchaban
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.33260

Abstract

One of the blockbuster drugs that has been off-patent and attract domestic pharmaceutical industry to produce a lot of version of me too is anti-hypertensive drugs Norvask®, in which the active ingredient is the salt form of amlodipine besylate. The goal of this study is to verify the conformity between me too drugs formulation and patent information (Case study: Amlodipine Tablets – PT Indofarma (Persero) Tbk). The results are expected to change the views of people who often doubt that me too drugs quality are smaller than patent drugs. The analysis method used in this study is performed descriptively. Information about amlodipine formulation obtained from PT Indofarma (Persero) Tbk is verified with the active substance test results obtained from amlodipine drugs on the market. After that, the total results can be compared with the proprietary patent information obtained from United States Patent and Trademark Office (USPTO) website. The result showed that there is a compatibilty between formulation of me too drugs and patent information (Case Study: Amlodipine – PT Indofarma (Persero) Tbk) in major issues such as compotition, active ingredient, level of active ingredient, dosage form and production process. Profile dissolution which is owned by amlodipine tablet from PT Indofarma (Persero) Tbk remains equivalent to the innovator product (Norvask®), although there was a modification by adding an excipient X. Amlodipine tablet generic produced by PT Indofarma (Persero) Tbk is me too 100% (identical).
SECONDARY PREVENTION TO REDUCE THE OCCURRENCE OF RECURRENT STROKE ON ISCHEMIC STROKE Hidayah Karuniawati; Zullies Ikawati; Abdul Gofir
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 5, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.23

Abstract

One of the purpose from stroke theraphy is to prevent recurrent stroke using secondary prevention by administering antiplatelet/anticoagulant, antihypertensive, antidyslipidemia, and antihyperglycemic. This study aimed to find the influence of secondary prevention on the occurrence of recurrent stroke and determine the factors that involve in the occurrence of recurrent stroke. This research was conducted with a quantitative approach and retrospective case-control study. The subjects were 165 respondents consisted of 82 respondents in the case group and 83 respondents in the control group. Data were analyzed using bivariate/chi square and logistic regression multivariate test. The result showed that the secondary prevention and patient’s compliance reduced the incident of recurrent stroke. The rate of recurrent stoke was decreased from 68% to 24% by antiplatelet therapy and compliance, from 69% to 23% by antihypertensive and compliance, from 54% to 29% by antidislipidemic and compliance, from 52% to 23% by antihiperglikemic and compliance, and the combination of these four secondary preventions reduced the recurrent stroke from 52% to 13%. Multivariate analysis showed that the several factors involved in determining the rate of recurrent stroke, namely patiens who did not use antihypertensive therapy (P=0,000; OR 9.871), had systolic blood pressure≥140mmHg (P=0,011; OR 3,156), HDL<40mg/dl (P=0,005; OR 3,594), and the lack of exercise (P=0,048; OR 2,365).Keyword: recurrent stroke, secondary prevention, compliance, antihypertensive therapy
THERAPY COST ANALYSIS AND EFFECTIVENESS OF TREATMENT OF OUTPATIENT WITH TYPE 2 DIABETES MELLITUS AT RSUD SLEMAN YOGYAKARTA Pratiwi Dinaryanti; Achmad Fudholi; Tri Murti Andayani
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.54

Abstract

Diabetes is a chronic disease that can significantly increase a person›s risk of having complications. These complications not only cause the inability of the body that will affect the quality of life, but also need big cost. This research was conducted to analyze the costs and effectiveness of therapies of outpatient with type 2 diabetes mellitus. A crosssectional observational method was performed on 100 patient who were admitted to the Department of Endocrinology of the Sleman Hospital between December 2010 to January 2011. Data were taken in 2 ways: concurrent and retrospective, with accidental sampling technique. The subject of this research were outpatient with type 2 diabetes mellitus at RSUD Sleman Yogyakarta, who have used the antidiabetic therapy for at least three months of therapy before the quality of life measurement. The costs that are measured are direct medical costs, antidiabetic costs, complication costs, laboratory examination costs, and administration costs. The effectiveness of treatment parameters was measured based on the percentage of patients with fasting blood glucose level (GDP) and post-prandial blood glucose (GDPP) which reached the target in the third month of therapy, and achievement of the quality of life research subjects. The Lowest total cost of therapy was the use of glibenclamide, it was 49.730,00, the highest total cost of therapy was the use of insulin, it was Rp. 411.045,50. T test results with 95% confidence level indicates that the patient characteristics and medication adherence complications affect the patients quality of life, whereas non-pharmacological therapy (exercise and diet) did not significantly influence the patients quality of life. The results of measurements of quality of life showed metformin achieved the best quality of life than the other antidiabetic, i.e. 72.53. Based on the effectiveness of the three parameters (measurement of quality of life and levels of GDP and GDPP) note that metformin therapy tend to be more effective compared with other antidiabetic therapies.Key words: Diabetes mellitus type 2, cost analysis, effectiveness, antidiabetic, RSUD Sleman Yogyakarta.
PENGARUH BAURAN PEMASARAN TERHADAP TAHAP KEPUTUSAN DOKTER MEMILIH VAKSIN HEPATITIS B UNTUK ORANG DEWASA DI RUMAH SAKIT Abdul Aziz Setiawan; Masruchin Masruchin; T. Djoharsyah
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 6, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.345

Abstract

Penyakit hepatitis telah menjadi masalah kesehatan di dunia, diperkirakan 1 juta orang meninggal setiap tahunnya akibat sirosis dan kanker hati. Di Indonesia diperkirakan 13 juta orang menderita hepatitis B, sekitar 50% berpotensi menjadi penyakit hepatitis kronis, bila tidak diobati secara baik maka 10% diantaranya dapat menjadi liver fibrosis sebagai cikal bakal kanker hati. Tujuan penelitian ini adalah untuk mengetahui dan menganalisis pengaruh bauran pemasaran terhadap tahap keputusan dokter melakukan vaksinasi hepatitis B untuk orang dewasa di Rumah Sakit Cipto Mangunkusumo, Jakarta.  Pengumpulan data yang dilakukan dalam penelitian ini adalah survey-cross sectional dari bulan  Agustus 2012 sampai dengan bulan Desember 2012 di Rumah Sakit Cipto Mangunkusumo, Jakarta. Pengambilan sampel dilakukan secara non-probabilitas sampling – purposive sampling sebanyak 61 dokter internist, 21 dokter internist diambil untuk uji pendahuluan dan 40 dokter internist diambil setelah uji validitas dan realibilitas. Pengujian hipotesa menggunakan analisa regresi berganda, uji t dan uji F pada tingkat kepercayaan 95% (a = 5%). Hasil analisa menunjukkan uji koefisien determinasi variabel produk, harga, tempat dan promosi memberikan kontribusi pengaruh sebesar 24,8% terhadap tahap keputusan dokter. Variabel harga dan promosi secara parsial berpengaruh signifikan terhadap tahap keputusan dokter. Sedangkan secara simultan terdapat pengaruh secara signifikan antara variabel produk, harga, tempat dan promosi terhadap tahap keputusan dokter di Rumah Sakit Cipto Mangunkusumo, Jakarta.
EVALUATION OF VALPROIC ACID DOSE USED FOR PAEDIATRIC WITH EPILEPSY Herningtyas Nautika Lingga; Lukman Hakim; I Dewa Putu Pramantara
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 3, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.112

Abstract

Epilepsy is a chronic disease in neurology and the second most common disorder after stroke. Valproic acid is categorised to the medicine with a narrow therapeutic index which requires monitoring of plasma drug levels and dose adjustments to prevent toxic effects. This study aimed to determine the estimated value of valproic acid concentration in serum and clinical outcomes in paediatric patients with epilepsy observed from seizure-free duration at Sleman Regional General Hopital, Yogyakarta. This study was a retrospective study with descriptive observational design. Subjects were paediatric patients with epilepsy who received valproic acid treatment over the period of January 2010-December 2012, 1 to 18 years old, boys or girls who were routinely controlled for at least 6 consecutive months. Clinical outcomes were observed through the duration of the seizure-free which were devided into 2 categories i.e. <6 months (unfavorable outcome), and ≥ 6 months (a good outcome). The proportion of 99 patients who met the inclusion criteria were 27.28% less than or equal to 5 years old, whereas 5-12 years and 12-18 years age groups had the same percentage which was 36.36%. From the calculation, average estimated value of valproic acid concentrations in serum for girls group were as much as 86.32±49.25 mg/L and 33.26±22.06 mg/L, while in boys group were as much as 94.91±44.72 mg/L and 38.57±20.72 mg/L. Based on the duration of seizure free, clinical outcome showed that the percentage of patients in monotherapy group had good and poor outcomes with 52.33% and 46.67% respectively, while 61.54% and 38.46% of patients in polytherapy group had good and poor outcome respectively.Keywords: Epilepsy, Valproic Acid, Clinical Outcome, Paediatric

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