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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Published by Universitas Gadjah Mada
ISSN : 20888139     EISSN : 24432946     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.
Arjuna Subject : -
Articles 515 Documents
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Patients' Perception of Waiting Time and Pharmacy Service of Hospital X Bali Antari, Ni Putu Udayana; Megawati, Fitria; Suwantara, I Putu Tangkas; Palguna, I Gede Rizky; Widnyani, Ni Kadek Indah Amelia; Wahyuni, Ni Wayan Mita Sri
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101783

Abstract

Background: Many hospitals are having problems with waiting times. Meanwhile, the effect of waiting time on perceived pharmacy service quality is inconsistent. Waiting time and pharmacy service quality can influence a hospital's image through patient perception.Objectives: To identify factors influencing patients' perceptions of waiting time and pharmacy service quality.Methods: The study used a cross-sectional design with one hundred samples, which were taken using the convenience sampling method. Data were collected using questionnaires and direct observation at Hospital X and analyzed using SPSS version 26 in a 95% CI.Results: Actual and patient-perceived waiting times differed significantly (Wilcoxon test, P-value 0.005). Age significantly affected patient perceptions of pharmacy service quality in both bivariate and multivariate tests (Chi-square: P-value 0.032; Logistic regression: P-value 0.023, adjusted OR: 2.594 (Min: 1.138; Max: 5.912)). Even though included in the equation, the actual waiting time is not significantly associated with patient perceptions.Conclusion: Patients did not perceive waiting times in accordance with the actual waiting time because emotional factors easily influence the perception of time. Pre-elderly and elderly patients at Hospital X perceive pharmacy services dominantly as good quality. Age significantly influences patients' perception of pharmacy service quality. Actual waiting time may influence patients' perception of pharmacy service quality if other factors are controlled. Hospitals should consider age and emotional factors when waiting for services to maintain patients' good perceptions of pharmacy service.
The Association Between Medication Adherence and Drug-Related Problems (DRPs) with Clinical Outcomes of Diabetes Patients at Public Health Center in Salatiga Hati, Anita Kumala; Yasin, Nanang Munif; Kristina, Susi Ari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.104444

Abstract

Background: Diabetes mellitus (DM) is a disease whose clinical condition can be controlled. The clinical outcomes of DM patients are an important parameter for successful treatment and are influenced by many factors.Objectives: This study aimed to analyze the relationship between medication compliance and drug-related problems (DRPs) with the clinical outcomes of diabetes patients at three Primary Health centers in Salatiga.Methods: An observational study method was adopted with prospective data collection from the medical records and medication compliance observation of type 2 diabetes mellitus (T2DM) patients, in October 2023–April 2024. DRP analysis was based on categories Cipolle, 2012, and medication compliance was measured using the pill count method. Data analysis was conducted using the Spearman test to assess the correlation between medication adherence and HbA1c levels, as well as the occurrence of DRP.Results: A total of 40 subjects participated in this study, with the largest gender being female (72.5%), and hypertension was the most common comorbid condition (55%). The highest compliance rate in patients was 40% and DRP events were detected in 107 cases. The difference in patient HbA1c levels at baseline and the 3rd month showed a significant difference, and 67.5% experienced an increase. Furthermore, there was a strong relationship between compliance and HbA1c achievement (sig = 0.003, r = 0.452), as well as between the incidence of DRP and HbA1c achievement (sig = 0.000, r = 0.644).Conclusion: Compliance and DRPs influenced the HbA1c levels of T2DM patients in PROLANIS across three Public Health Centres in Salatiga.
Assessment of Prescribing Practice for Caesarean Section : Adherence to the Indonesian National Formulary Nurmainah, Nurmainah; Arfida, Khaizurani; Ulfah, Ridha
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.104754

Abstract

Background: The increasing prevalence of Caesarean Section (SC) deliveries and non-compliance with the National Formulary can lead to financial burdens for hospitals due to claim failures and higher drug costs. Understanding this relationship is crucial for improving cost efficiency and ensuring sustainable healthcare financing.Objectives: This study aims to analyse the percentage of prescribing compliance with the National Formulary and its impact on pharmacotherapy costs and the real costs of SC treatment at RSUD Dr. Soedarso.Methods: This research is an observational study with a cross-sectional design. Used medical record data of mild severity SC patients for the period January-December 2023. The sample consisted of 472 patients selected by purposive sampling. Descriptive Analysis and Spearman correlation were used to evaluate the relationship between prescribing compliance, pharmacotherapy cost, and real cost.Results: Adherence to the national formulary (97.10%). Spearman’s correlation analysis shows a significant negative correlation between adherence and pharmacotherapy costs. However, adherence has no significant correlation with total treatment costs, suggesting that factors like length of stay play a greater role.Conclusion: A significant negative correlation exists between compliance and pharmacotherapy cost, but no significant correlation with real costs. Future research should explore the relationship between total treatment costs and Length of Stay (LOS).
Translation and Validation of the Indonesian Version of Oral Chemotherapy Adherence Scale (OCAS) Puspitasari, Atika Wahyu; Kristina, Susi Ari; Satibi, Satibi; Prabandari, Yayi Suryo
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.105128

Abstract

Background: Medication adherence is essential for oral anticancer agents (OAAs) to succeed and maintain the optimal therapeutic outcomes. However, there are no well-established instruments in Indonesia to evaluate adherence to oral chemotherapy by cancer patients.Objectives: This study aimed to validate and translate the Oral Chemotherapy Adherence Scale (OCAS) for cancer patients in Indonesia.Methods: Data were collected from patients taking oral chemotherapy for at least a month at Dharmais Cancer Hospital in Jakarta. OCAS was translated into Indonesian using a forward-backward translation method. Content validity was assessed through expert review to calculate Content Validity Index (CVI), while face validity was evaluated to confirm cultural relevance and readability. Internal consistency was measured using Cronbach's alpha.Results: A total of 131 patients participated from August to December 2021. Content validation by seven experts showed that the mean I-CVI of the items was above 0.79, with an S-CVI of 0.985, reflecting the validity of the items. Furthermore, face validity confirmed the readability and clarity of Indonesian version of OCAS. Reliability testing showed a Cronbach alpha of 0.871, suggesting strong internal consistency.Conclusion: Indonesian OCAS was a valid instrument for evaluating medication adherence in Indonesian cancer patients taking oral chemotherapy. Therefore, it can be used for adherence monitoring in healthcare settings.
Achieving Hospital Efficiency through Inventory Management Strategies: A Systematic Review Sulistioningsih, Emi; Satibi, Satibi; Yuniarti, Endang
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.112087

Abstract

Background: In developing countries, pharmaceutical expenditures account for approximately 40–50% of total hospital costs. Therefore, effective management of medicines and pharmaceutical supplies is essential, as it significantly influences hospital operational efficiency and the quality of healthcare services.Objectives: This study aims to evaluate the impact of Economic Order Quantity (EOQ), Reorder Point (ROP), and Minimum-Maximum Stock Level (MMSL) inventory management methods on hospital efficiency.Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were applied to operate this systematic review. The articles published between 2009 and 2024 were identified through searches of Scopus, PubMed, Google Scholar, and the Garuda database. Studies that reported the application of EOQ, ROP, or MMSL methods in hospital pharmaceutical inventory management were included. A total of nine eligible studies were reviewed and synthesized to evaluate their impact on inventory efficiency indicators.Results: Nine studies met the inclusion criteria. Four studies applied EOQ and ROP methods, while five studies implemented the MMSL methods. The efficiency indicators evaluated inventory value, dead stock, stock out, inventory turnover ratio (ITOR), and customer service level. EOQ and ROP methods were associated with reductions in inventory value and stockouts, as well as improvements in ITOR and customer service levels. The MMSL generally reduced inventory value, stockout frequency, stockout value, and dead stock, either significantly or non-significantly, and increased ITOR. However, one study reported an increase in inventory value due to unstable supply conditions before implementation, and another reported a decrease in ITOR related to ordering policy constraints. Overall, the findings suggest that the EOQ, ROP, and MMSL methods generally improve inventory efficiency; however, several studies reported inconsistent or non-significant effects on certain indicators, such as the inventory turnover ratio and inventory value, under specific operational conditions.Conclusion: This systematic review indicates that the Minimum–Maximum Stock Level and Economic Order Quantity, Reorder Point methods are potentially beneficial strategies for enhancing inventory efficiency in hospital settings.
Multiple Criteria Decision Analysis for Off-Patent Pharmaceuticals in Health Care: Bibliometric Analysis and Scoping Review Ratih Puspita Febrinasari; Erna Kristin; Aiman Hilmi Asaduddin; Meutia Filzan Kamilah; Dinari Febriyanti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.100349

Abstract

Background: Multi-Criteria Decision Analysis (MCDA) is a structured approach used for evaluating complex decisions that involve multiple criteria. In the context of healthcare, its use has grown significantly for benefit–risk assessments, formulary decisions, and reimbursement processes. In developing countries, MCDA has been proposed to support evidence-based evaluation of off-patent pharmaceuticals (OPPs), helping improve public health outcomes and access to quality medicines. However, existing reviews remain limited in scope, emphasizing the need for an updated bibliometric overview of MCDA applications in OPPs.Objectives: This study aims to provide a comprehensive bibliometric analysis of MCDA research in healthcare, with a specific focus on OPPs.Methods: Searches were conducted in Scopus, PubMed, and Epistemonikos from January 1985 to October 2023. Eligible studies included full-text English articles utilizing MCDA in OPP procurement. Data were extracted on decision contexts, criteria, methodologies, and stakeholder involvement. Bibliometric analysis was conducted using Scopus Analyzer, VOSviewer, and Microsoft Excel.Results: A total of 2,210 MCDA-related healthcare articles were identified from 1981 to 2023, with a marked increase after 2013. Dominant themes included decision-making, multicriteria analysis, and healthcare. The identification results showed that A.A. Zaidan was the most prolific author. Citation analysis reported 41,882 citations between 2011 and 2023. The scoping review identified seven studies focusing on MCDA for OPPs, highlighting quality as the most prioritized criterion in procurement frameworks.Conclusion: MCDA frameworks offer a comprehensive approach to improve healthcare decision-making and policy development, particularly in evaluating and procuring OPPs, while supporting adaptable implementation across diverse health systems.
Effectiveness and Limitations of Spiramycin for Toxoplasmosis During Pregnancy: A Systematic Review Noor Laila Harkaningdyah; Salma Auliya Fatimah; Ayu Anggresti; Lavia Dinta Nur Pratiwi; Nabila Risti Rachmadi; Andi Desiah Pranada
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.100761

Abstract

Background: Toxoplasmosis is brought on by the protozoan parasite Toxoplasma gondii. Toxoplasmosis can be transferred from a mother to her fetus during pregnancy, resulting in congenital illness. Spiramycin is administered in the early stages as a kind of prophylaxis for the fetus and can be continued until delivery. If the fetus becomes infected, therapy is altered to a triple mixture of sulfadiazine, folinic acid, and pyrimethamine.Objectives: This article aims to comprehensively review spiramycin as a prophylactic measure for preventing vertical transmission of infection to fetuses and its limitations, including adverse effects.Methods: This study used a systematic review approach of publications indexed in Scopus, PubMed, ScienceDirect, and Web of Science databases from 2014 to 2024. It utilized the PRISMA flow diagram to guide the article selection process until a conclusion was reached.Results: Based on the predetermined inclusion and exclusion criteria and in accordance with the topic of this research objective, six research articles were suitable for review. Among the six reviewed articles, spiramycin is the first-line therapy for preventing vertical transmission of Toxoplasma gondii to the fetus. The most common side effect of using spiramycin in pregnant women is paresthesia.Conclusion: Spiramycin has an important role in preventing congenital toxoplasmosis, but it is not recommended for infected fetuses. Instead, combination therapy is superior for treating infections that have occurred in the fetus.
Effectiveness of Opioids-Adjuvant Analgesics Combinations for Pediatric Cancer Pain: A Systematic Review Ulfa Filliana; Susi Ari Kristina; Bekti Meilani Nurcahya
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.100789

Abstract

Background: The pediatric cancer was reported that they got worst pain and 40% weren’t managed well. The impact of untreated cancer pain is low quality of life and poor pain experienced. Therefore, it is important to know the best analgesic for improving the clinical outcome of pain.Objectives: This study aims to determine the effectiveness of using opioid combined with adjuvant analgesics based on WHO analgesic ladder in pediatric cancer pain.Methods: PubMed and Science Direct were searched for randomized controlled trials and retrospective studies by the keyword’s “opioid”, “adjuvant analgesic”, “pediatric”, “cancer” within 2014-2024. The primary outcome was using Faces Pain Scale, or visual analog scale (VAS), or numerical rating scale (NRS).Results: A result of 556 studies were reviewed. After further inspection of collected studies, only 5 studies achieved all inclusion criteria. The final studies consist of two prospective studies with randomized trial and three retrospective studies. Combination gabapentin or pregabalin as adjuvant analgesic with opioids was better reduced pain intensity and less adverse events than other combinations.Conclusion: This study supports the increased effectiveness of analgesic opioid combined with adjuvant analgesics, compared with single opioid, in the treatment of pediatric cancer pain. Further study inspires researchers to conduct studies using the randomized trial method and continue meta-analysis study especially in pediatric population and developing countries.
Comparing the Effectiveness of Metformin–Acarbose and Metformin–Sulfonylurea Combination Therapies in Patients with Type 2 Diabetes Mellitus at Diponegoro National Hospital Syarifah Khaerunnisa; Eva Annisaa'; Fitri Wulandari
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101082

Abstract

Background: Diabetes mellitus is a major non-communicable disease and accounts for approximately 4% of deaths in Indonesia. The effectiveness of type 2 diabetes mellitus (T2DM) treatment is generally evaluated using HbA1c, fasting blood sugar (FBS), postprandial blood sugar (PPBS), and the incidence of hypoglycemia—the most concerning complication. Multiple combination therapy regimens are available, each with varying levels of effectiveness.Objectives: This study aimed to compare the effectiveness of metformin–sulfonylurea and metformin–acarbose combination therapies in T2DM patients, as measured by HbA1c, FBS, PPBS, and hypoglycemia incidence at Diponegoro National Hospital.Methods: A cross-sectional observational study with a retrospective design was conducted. Secondary data were collected between January 2021 and June 2023 using purposive sampling. Eligible patients had received regular drug therapy for at least three months.Results: Among patients receiving metformin–sulfonylurea, glycemic control was achieved in 82.3% for FBS, 82.3% for PPBS, and 48.4% for HbA1c, with 82.3% showing no hypoglycemia. In patients receiving metformin–acarbose, glycemic control was achieved in 66.1% for FBS, 67.7% for PPBS, and 32.3% for HbA1c, with 96.8% showing no hypoglycemia.Conclusion: Significant differences in effectiveness were observed between metformin–sulfonylurea and metformin–acarbose with respect to FBS and hypoglycemia incidence, whereas no significant differences were found for PPBS and HbA1c. These findings suggest that both regimens are generally effective. Metformin–sulfonylurea may be preferred when stricter glycemic control is desired, while metformin–acarbose may be more suitable for patients at higher risk of hypoglycemia.
Cost-Effectiveness Analysis of Amlodipine–Candesartan and Amlodipine–Furosemide in Hypertensive Inpatients at RSUD Dr. Loekmono Hadi Kudus, 2023 Yulia Pratiwi; Mutia Arum Masitoh; Annis Rahmawaty; Mersi Riyanti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.103302

Abstract

Background: Hypertension is a major public health problem and a leading risk factor for cardiovascular morbidity and mortality. In hospitalized patients, combination antihypertensive therapy is frequently used to achieve optimal blood pressure control, which may lead to increased healthcare costs. Therefore, evaluating the cost-effectiveness of commonly used antihypertensive combinations is essential to support rational drug selection in hospital settings.Objectives: This study aims to analyze the cost-effectiveness of amlodipine–candesartan and amlodipine–furosemide combination therapies for inpatient hypertension treatment at RSUD dr. Loekmono Hadi Kudus in 2023.Methods: This non-experimental, descriptive study employed a retrospective design using medical record and cost data from 88 hypertensive inpatients. Patient characteristics, length of hospital stay, therapeutic effectiveness, and direct medical costs were analyzed. Therapeutic effectiveness was defined as the proportion of patients achieving target blood pressure based on JNC VIII guidelines. Cost-effectiveness was assessed using the Average Cost-Effectiveness Ratio (ACER) and Incremental Cost-Effectiveness Ratio (ICER).Results: The amlodipine–candesartan combination demonstrated a lower ACER (Rp48,229 per 1% effectiveness) than amlodipine–furosemide (Rp90,275). The ICER value (−Rp597,651) indicated that amlodipine–candesartan was both more effective and less costly. Higher costs in the amlodipine–furosemide group were associated with injectable drug use and a greater proportion of prolonged hospital stays.Conclusion: Amlodipine–candesartan was more cost-effective than amlodipine–furosemide for managing hypertensive inpatients. These findings support the preferential use of amlodipine–candesartan when clinically appropriate to optimize both clinical outcomes and healthcare resource utilization.

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