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INDONESIA
BIOEDUSCIENCE
Published by Universitas Muhammadiyah Prof. Dr. Hamka
ISSN : 2614154X     EISSN : 26141558     DOI : -
Core Subject : Science, Education, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education
BIOEDUSCIENCE is an open access journal that publishes research in the field of Biology and Biosain Education such as: Applied and implemented in education and learning, Botany, Zoology, Microbiology, Ecology, Biotechnology, Molecular Biology, Genetics, Bioinformatics, Cell and Developmental Biology, Biodiversity and Bioconservation. BIOEDUSCIENCE is published by Biology Education Study Program, Universitas Muhammadiyah Prof. Dr. Hamka, Indonesia regularly in June and December. ISSN : 2614-1558; P-ISSN : 2614-154X.
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Articles 39 Documents
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Search results for , issue "Vol 4 No 2 (2020): BIOEDUSCIENCE" : 39 Documents clear
Korelasi antara Keterampilan Generik Sains dan Sikap Ilmiah terhadap Hasil Belajar Peserta Didik pada Materi Sistem Koordinasi di Kelas XI SMA Negeri 2 Tasikmalaya Suci Ismiatul Hasanah; Romy Faisal Mustofa; Ryan Ardiansyah
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/424942

Abstract

Background: Various factors can support efforts to improve student learning outcomes, including generic science skills and scientific attitudes. The study aims to determine the correlation between generic science skills and scientific attitudes on student learning outcomes. Methods: This research is a correlational study using a dual paradigm design with two independent variables. The sample was that used was 60 people who came from 11th grade of Science Program. Result: The result of this research is that there is a strong and very significant correlation between generic science skills and scientific attitudes towards learning outcomes. This is supported by the data analysis results, namely a significance value of 0.000 and a correlation coefficient of 0.623. Conclusion: It could be concluded that generic science skills and scientific attitudes contribute to improving student learning outcomes because students who have generic science skills and an excellent scientific attitude will get optimum learning outcomes. Therefore, generic science skills and scientific attitudes that exist in students must continue to be trained and developed.
Analysis of Molecular Interactions of 8-Gingerol Compounds in Ginger (Zingiber officinale) as ACE Inhibitor Yohanes Bare; Mansur s; Aprianus Pani Pili; Maria Helvina
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/424944

Abstract

Background: Hypertension is a disease with increasing characteristics of blood pressure. The ACE gene has a role in the conversion of ATI to ATII in hypertensive conditions. Healing is done by using the 8-gingerol content contained in ginger. The purpose of this study is to analyze the molecular interaction that occurs between 8-gingerol and ACE. Method: ACE model proteins (ID: 3bkk) were obtained from the Bank Data Protein database (PDB) through 8-gingerol ligands (CID: 168114) obtained from the PubChem database. ACE and 8-gingerol were docked by Discovery Study Client 4.1 software. Analysis of amino acid residues, binding energy, Van der Waals forces, and hydrogen bonds formed using Discovery Studio Client 4.1. Results: The interaction between 8-gingerol and ACE showed that there were seven amino acid residues that interacted with 8-gingerol, also found hydrogen bonds, hydrophobic and Van der Waals forces that strengthen and stabilize these bonds. Conclusion: the interaction of 8-ginger with the active side of ACE is determined as an ACE inhibitor, the inhibition is a significant effect on the obstruction of ACE conversion.
Hubungan Kekerabatan Fenetik Famili Apocynaceae Berdasarkan Karakter Morfologi dan Anatomi Ahsanul Buduri Agustiar; Dewi Masyitoh; Irda Dwi Fibriana; Adesilvi Saisatul Khumairoh; Kurnia Alfi Rianti; Norma Fitriani; Muhammad Harissuddin; Hafidha Asni Akmalia
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/424945

Abstract

Background: Biodiversity in Indonesia is so diverse, including in Apocynaceae plants that is why it is important to study the kinship relationship to find out the kinship of Apocynaceae. The purpose of this study was to determine phenetic kinship through morphological and anatomical evidence from four members of the Apocynaceae family. Methods: The method used in this research is descriptive qualitative and quantitative method. The samples in this study were four species of Apocynaceae family members, including Adenium obesum, Plumeria rubra, Catharanthus roseus, and Allamanda cathartica. The indicators used were the morphological traits of stems, leaves, and flowers and the anatomical trait of stomata. Results: The result showed that the phenetic kinship of the four species of the Apocynaceae family member namely Alamanda cathartica had a distant kinship relationship with the other species with a similarity value of 31%. Conclusions: Thus, the familial relationship between species in the Apocynaceae family in terms of morphological and anatomical characters that have a close relationship with Plumeria rubra and Adenium obesum with a similarity value of 44% and the most distant Alamanda cathartica with a similarity value of 31%.
Subchronic Toxicity Test of Indian Almond (Terminalia catappa) Leaves Water Extract on The Liver Histology of Mice (Mus musculus) Nugroho Rudy; Ni Cening Sri Puspa; Retno Aryani; Widha Prahastika; Rudianto Rudianto; Hetty Manurung
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/425173

Abstract

Background: Indian almond (Terminalia catappa) is used as an alternative medicine by the community to treat various diseases. However, limited research has been conducted on the subchronic toxicity of Indian almond water extracts on the liver. Present study aimed to determine the subchronic toxic effects of Indian almond leaf water extract on the liver histology of mice and to evaluate the safe dose of Indian almond leaf water extract with various doses (125, 250, 500, 750 and 1000 mg/kg). Methods: In total of 33 male mice were randomly divided into 11 groups, each group consisting of three mice as replication. For 30 days, mice in five treatment groups were orally treated every day with water extracts of green Indian almond leaf while other five groups were given water extracts of brown Indian almond leaves and compare with control group. At the end of day 30, all mice were sacrificed, and hepar was taken out for histological preparations. The histopathological changes in the liver was observed and assessed based on histological damage in the term of degeneration and necrosis. Results: The administration of green and brown Indian almond water extract at doses of 125, 250, 500, 750 and 1000 mg / kg BB showed a toxic effect on the liver of mice. The toxic effect was due to the high doses, causing a cell swelling damage and increased liver necrosis. Conclusion: Indian almond leaf water extract can cause toxic effects on the liver of mice at the doses implemented.
HA Aktivitas Antimikroba dan Identifikasi Gen Penyandi Enterocins isolat Enterococcus faecalis K2B1 dari Susu Kerbau Belang Toraja: Antimikroba dan Gen Penyandi Hasria Alang; Joni Kusnadi; Tri Ardyati; Suharjono Suharjono
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/425193

Abstract

Background: Enterocin in Enterococcus is coded by enterocin encoding genes namely A, B, P and L50A / B. The purpose of this study was to identify enterocin gene encoding enterococcus faecalis K2B1 probiotic candidate from Belang Toraja buffalo milk and antimicrobial activity to S. typhi. Methods: identification of enterocin gene encoding using ent A, B, P and L50A / B, partial purification using ammonium sulfate on 80 % concentration and antimicrobial activity against to Salmonella typhi using disk diffusion method. The results of PCR amplification are then sequenced and BLASTX on NCBI. Result: Antimicrobial activity of Precipitate and crude against S. typhi are 193 and 201 respectively. Identification gene encoding enterocin shows that Ent A, B and P cannot be amplified and only EntL50A / B can be amplified with a sequence size of 86 bp. The sequence of enterocin encoding genes in E. faecalis K2B1 has 94% similarity with hypothetical protein EB34_00789 E. faecalis on GenBank with accession number RBR60004.1 Conclusion: EntL50A / B E. faecalis K2B1 has a size of 86 bp and is 94% identical to the hypothetical protein EB34_00789 and Enterocin can be used as antimicrobial or bio preservative.
Analisis Kemampuan Literasi Bahasa dalam Konteks Pembelajaran Biologi Jihan Azhaar Ramadhanty; Vita Meylani; Edi Hernawan
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/425194

Abstract

Background: The results of PISA showed that Indonesian students' literacy skills in the field of science are still low. Until now, the cause of the problem is still little information reported. This study was conducted to analyze the language literacy skills of students in biological learning contexts. Methods: the methods used in the research is mixed methods research. This research involved 72 science program students who were selected by purposive sampling. The data were gained by observations, interviews and giving the posttest consisting of 17 questions of multiple-choice based on the Programme for International Student Assessment (PISA) indicator for language literacy in biological learning. Results: That the analysis of language literacy in the context of Biological learning has an excellent literacy with a high category. The research showed that the highest average grade of language literacy was in the integrate and interpret aspects of 75,00. Meanwhile, the lowest average grade in the reflect and evaluate aspects was 57,00. The average overall grade in the language literacy on Biological learning was 70,22. Conclusion: Sustainable literacy activities stimulate higher-order thinking skills, especially in the field of science, because language literacy skills can indirectly affect students' outcomes on scientific skills.
Pengaruh Paparan Asap Rokok Elektrik terhadap Histologi Paru Mencit (Mus musculus L.) Strain Balb/c Jantan Eva Tyas Utami; Bella Dwi Arifianti; Mahriani Mahriani; Susantin Fajariyah
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/425319

Abstract

Background: Electric cigarette is a type of cigarette that change the liquid containing nicotine and other ingredients in the form of steam. This research aimed to identify the effect of exposure to e-cigarette smoke towards the thickness of bronchioles mucosa and the alveolar septa on male Balb'C mice (M. musculus). Methods: This research was an experimental design used 24 male divided into four groups, i.e., control dan three treatment groups. Treatment groups were given different volume of e-cigarettes liquid, i.e., 1 ml; 2 ml; and 4 ml. The exposure of e-cigarette was done in 4 weeks, respectively. Results: Electric cigarette exposure with different fluid volumes leads to an increase in the bronchioles mucosa's thickness and the alveoli septa. Increasing the volume of fluid used results in an increase in bronchioles mucosal thickness, but decreases the alveoli septa's thickness, resulting in destruction and dilatation of the alveoli. Conclusion: Exposure to e-cigarette smoke with a liquid volume of 1 ml affects the increase in the average thickness of the bronchial mucosa and alveoli septa. An increase in the average thickness of the bronchioles mucosa occurs along with increased fluid volume in exposure to e-cigarette smoke.
Pembelajaran Berbasis Budaya Meningkatkan Hasil Belajar Kognitif Siswa SMA di Kota Denpasar I Made Surya Hermawan; Hadi Suwono; Herawati Susilo; Desak Nyoman Budiningsih
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/425582

Abstract

Background: One of the learning objectives is to develop a cognitive process dimension seen in cognitive learning outcomes. In fact, this has not been implemented optimally in the learning process. The Balinese culture-based biology learning model is seen as an alternative to developing the cognitive process dimension. This study aims to reveal the effect of the Balinese culture-based biology learning model through the cognitive learning outcomes of high school students in Denpasar City. Methods: This study was conducted using a non-equivalent pretest-posttest control group design. The research subjects were 144 students who were taken using cluster random sampling technique. The data collection instrument was in the form of multiple choices questions which were categorized into questions of lower-order thinking skills (LOTS) and questions of higher-order thinking skills (HOTS). Results: The results of data analysis showed that: 1) there was a significant difference in cognitive learning outcomes between the experimental class and the control class (p <0.05); 2) the Balinese culture-based biology learning model increased students' cognitive learning outcomes by 18.21%; 3) the Balinese culture-based biology learning model improves lower-order thinking skills (LOTS) by 8.44% and higher-order thinking skills (HOTS) by 17.92%. Conclusions: This study concludes that the Balinese culture-based biology learning model improves cognitive learning outcomes and has the potential to develop higher-order thinking skills of high school students in Denpasar City.
Diferensiasi Gonad Ikan Nilem (Osteochilus vittatus) dengan Perlakuan Suhu: Diferensiasi Gonad Ikan Nilem Aulidya Nurul Habibah; Rika P.C. Pertiwi; Titi Chasanah
BIOEDUSCIENCE Vol 4 No 2 (2020): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/j.bes/425704

Abstract

Background: Gonad differentiation in some teleostei is a critical phase of gonad development. Gonad differentiation in some fish such as the tilapia group is influenced by environmental factors, namely temperature. The aim of this study was to determine the differentiation process of Nilem fish gonads (Osteochilus vittatus) under the influence of temperature. Methods: One day after fertilization (days postfertilization/dpf) fish were exposed to different medium temperature ranges, namely: 28-29 oC, 30-31 oC, 32-33 oC, and room temperature as a control for 35 days. The percentage of fish survival was calculated on the 35th day by calculating the number of surviving fish divided by the total number of fish in 1 tank times 100%. Thirty fish in each treatment were measured for body length at day 10 dpf and day 35 dpf to determine fish growth. Six fish 35 dpf from each treatment were fixed in 70% alcohol for making histological preparations using the paraffin method, Haematoxylin-Eosin staining. Fish survival data growth data in the form of fish length were analyzed using Anova. Gonadal differentiation data were analyzed descriptively. Results: There was no significant difference in the growth of fish in all treatment and control groups. The average survival rate of fish in all treatment and control groups was 100%. Observation of the gonads showed that the gonads were not differentiated in all treatment and control groups. Conclusion: The room temperature range up to 33 oC supports the growth of Nilem fish with gonad development in the indifferent gonad stage.

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